ViewGene
Locus Name:
GeneID:
Location:

GeneID:903
TrivialName: PA14_15310
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_15310
PAO1 Ortholog Locus:PA3770
Sequence Length:1470
Protein Length:489
Start: 1297693
Stop: 1299162
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07157.1|AE004796_2 (AE004796) inosine-5'-monophosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
Identities = 489/489 (100%), Positives = 489/489 (100%)
Sequence:
ATGCTGCGAATCAGTCAAGAAGCCCTGACTTTCGACGACGTCCTTCTGATCCCCGGTTATTCCGAAGTCCTG
CCCAAGGACGTGAGTTTGAAAACTCGCCTGACCCGCGGCATCGAACTGAACATCCCGCTGGTATCCGCCGCG
ATGGATACCGTGACCGAAGCCCGCCTGGCCATCGCCATGGCCCAGGAAGGCGGCATCGGCATCATCCACAAG
AACATGGGCATCGAGCAGCAGGCCGCGGAAGTCCGCAAGGTCAAGAAGCACGAGACGGCCATCGTCCGCGAC
CCGGTCACCGTGACCCCCTCGACCAAGATCATCGAACTGCTGCAGATGGCCCGCGAGTACGGCTTCTCCGGC
TTCCCGGTGGTGGAGCAGGGCGAGCTGGTCGGTATCGTCACCGGTCGCGACCTGCGGGTGAAGCCGAACGCC
GGCGATACCGTCGCCGCGATCATGACCCCGAAGGACAAGCTGGTCACCGCCCGCGAAGGCACCCCGCTGGAA
GAGATGAAGGCCAAGCTCTACGAGAACCGCATCGAGAAGATGCTGGTAGTCGACGAGAACTTCTACCTGCGT
GGCCTGGTGACCTTCCGTGACATCGAGAAGGCCAAGACCTACCCGCTGGCGTCCAAGGACGAGCAGGGCCGC
CTGCGCGTCGGTGCCGCCGTCGGCACCGGCGCCGATACCGGCGAGCGCGTCGCCGCGCTGGTCGCCGCCGGG
GTCGACGTGGTGGTGGTGGACACCGCTCACGGCCACTCCAAGGGCGTGATCGAGCGCGTGCGCTGGGTCAAG
CAGACCTTCCCGGACGTCCAGGTGATCGGCGGCAACATCGCCACCGCCGAGGCCGCCAAGGCCCTCGCCGAG
GCTGGCGCCGACGCGGTCAAGGTCGGCATCGGCCCGGGCTCGATCTGCACCACCCGCATCGTCGCCGGTGTC
GGCGTGCCGCAGATCTCCGCCATCGCCAACGTCGCCGCCGCCCTCGAGGGCACCGGCGTACCGCTGATCGCC
GACGGCGGCATCCGCTTCTCCGGCGACCTGGCCAAGGCCATGGTCGCCGGCGCCTACTGCGTGATGATGGGC
TCGATGTTCGCCGGTACCGAGGAAGCGCCGGGCGAGATCGAGCTGTTCCAGGGCCGTTCCTACAAGTCCTAC
CGCGGCATGGGTTCGCTGGGCGCCATGTCCGGCTCCCAGGGCTCGTCCGACCGCTACTTCCAGGACGCCTCC
GCCGGCGCCGAGAAGCTGGTGCCGGAAGGCATCGAGGGTCGCGTGCCGTACAAGGGTGCCTTGTCCGCCATC
GTCCACCAACTGATGGGCGGCCTGCGCGCCGCCATGGGCTACACCGGCAGCGCCGACATCCAGCAGATGCGC
ACGCAGCCGCAGTTCGTCCGGATCACCGGCGCGGGCATGGCCGAGTCCCATGTCCACGACGTCCAGATCACC
AAGGAAGCCCCCAACTACCGGGTTGGTTGA
Translation:
MLRISQEALTFDDVLLIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHK
NMGIEQQAAEVRKVKKHETAIVRDPVTVTPSTKIIELLQMAREYGFSGFPVVEQGELVGIVTGRDLRVKPNA
GDTVAAIMTPKDKLVTAREGTPLEEMKAKLYENRIEKMLVVDENFYLRGLVTFRDIEKAKTYPLASKDEQGR
LRVGAAVGTGADTGERVAALVAAGVDVVVVDTAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAE
AGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG
SMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGALSAI
VHQLMGGLRAAMGYTGSADIQQMRTQPQFVRITGAGMAESHVHDVQITKEAPNYRVG*
AnnotationID:912GeneID:903
AnnotatorUID: diggins
Modification Date/Time: 2005-04-22 13:01:27
Gene Name:guaB
Confidence Code:2
GeneProduct:inosine-5-monophosphate dehydrogenase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:IMP dehydrogenase/GMP reductase
Functional Category Confidence Code:5
COGs:pfam00478,KOG2550,COG0516
Secondary Functional Category(ies):
EC Number:1.1.1.205
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66656.1|AE016293_6 (AE016777) inosine-5-monophosphate dehydrogenase [Pseudomonas
           putida KT2440]
          Length = 489

 Score =  775 bits (2000), Expect = 0.0
 Identities = 390/489 (79%), Positives = 440/489 (89%)

>gb|AAB18618.1| (M10101) IMP dehydrogenase [Escherichia coli]
          Length = 488

 Score =  643 bits (1659), Expect = 0.0
 Identities = 324/490 (66%), Positives = 400/490 (81%), Gaps = 4/490 (0%)








 
Structural Features:
pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain.
CD-Length = 468 residues, 100.0% aligned
Score =  637 bits (1645), Expect = 0.0
Identities = 280/472 (59%), Positives = 355/472 (75%), Gaps = 6/472 (1%)

KOG2550, IMP dehydrogenase/GMP reductase 
[Nucleotide transport and metabolism]
CD-Length = 503 residues,  94.0% aligned
Score =  413 bits (1062), Expect = 6e-116
Identities = 197/480 (41%), Positives = 287/480 (59%), Gaps = 16/480 (3%)

COG0516, GuaB, IMP dehydrogenase/GMP reductase 
[Nucleotide transport and metabolism]
CD-Length = 170 residues,  96.5% aligned
Score =  143 bits (361), Expect = 1e-34
Identities = 54/164 (32%), Positives = 76/164 (46%)






   
Genomic Context:






   
Comment:


















    ReferenceID:1809




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:18951




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31785




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:903_cdd.html


    		




 
URL:

















    ReferenceID:34274




  
Author/Investigator(s):
        Tiedeman AA, Smith JM.





  
Title:
        Nucleotide sequence of the guaB locus encoding IMP dehydrogenase of Escherichia coli K12.




  
PubMed:
        2860637


MedLine:
        




    
Source:
Nucleic Acids Res. 1985 Feb 25;13(4):1303-16.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2860637









           
Homologs By Global Alignment 

           

       



     
Gene ID:903
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1604
                           PA3770_tr
                           translation of PA3770
                           489
                           99.99
                           99.99
                           0
                           2441.0
     

     
     
57874
                           gb|AAG07157.1|AE004796_2
                           (AE004796) inosine-5'-monophosphate dehydrogenase [Pseudomonas aeruginosa PAO1]
                           489
                           99.99
                           99.99
                           0
                           2441.0
     

     
     
57875
                           gb|AAN66656.1|AE016293_6
                           (AE016777) inosine-5-monophosphate dehydrogenase [Pseudomonas putida KT2440]
                           489
                           79.75
                           89.97
                           0
                           2000.0
     

     
     
57876
                           gb|AAO54970.1|
                           (AE016861) inosine-5-monophosphate dehydrogenase [Pseudomonas syringae pv. tomato str. DC3000]
                           489
                           79.55
                           88.75
                           0
                           1986.0
     

     
     
57881
                           emb|CAA47328.1|
                           (X66859) IMP dehydrogenase [Acinetobacter calcoaceticus]
                           489
                           70.55
                           82.61
                           1
                           1731.0
     

     






      

          
GC ORFID: 43905How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3770Glimmer Score: 

          
Start: 3656244Stop: 3654775

          
Length: 1470


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3770 translation of PA3770Homolog Bit Score 944.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4540 (ORF: BLASTX 772.0), t_PA3770 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCTGCGAATCAGTCAAGAAGCCCTGACTTTCGACGACGTCCTTCTGATCCCCGGTTATTCCGAAGTCCTG 
CCCAAGGACGTGAGTTTGAAAACTCGCCTGACCCGCGGCATCGAACTGAACATCCCGCTGGTATCCGCCGCG 
ATGGATACCGTGACCGAAGCCCGCCTGGCCATCGCCATGGCCCAGGAAGGCGGCATCGGCATCATCCACAAG 
AACATGGGCATCGAGCAGCAGGCCGCGGAAGTCCGCAAGGTCAAGAAGCACGAGACGGCCATCGTCCGCGAC 
CCGGTCACCGTGACCCCCTCGACCAAGATCATCGAACTGCTGCAGATGGCCCGCGAGTACGGCTTCTCCGGC 
TTCCCGGTGGTGGAGCAGGGCGAGCTGGTCGGTATCGTCACCGGTCGCGACCTGCGGGTGAAGCCGAACGCC 
GGCGATACCGTCGCCGCGATCATGACCCCGAAGGACAAGCTGGTCACCGCCCGCGAAGGCACCCCGCTGGAA 
GAGATGAAGGCCAAGCTCTACGAGAACCGCATCGAGAAGATGCTGGTAGTCGACGAGAACTTCTACCTGCGT 
GGCCTGGTGACCTTCCGTGACATCGAGAAGGCCAAGACCTACCCGCTGGCGTCCAAGGACGAGCAGGGCCGC 
CTGCGCGTCGGTGCCGCCGTCGGCACCGGCGCCGATACCGGCGAGCGCGTCGCCGCGCTGGTCGCCGCCGGG 
GTCGACGTGGTGGTGGTGGACACCGCTCACGGCCACTCCAAGGGCGTGATCGAGCGCGTGCGCTGGGTCAAG 
CAGACCTTCCCGGACGTCCAGGTGATCGGCGGCAACATCGCCACCGCCGAGGCCGCCAAGGCCCTCGCCGAG 
GCTGGCGCCGACGCGGTCAAGGTCGGCATCGGCCCGGGCTCGATCTGCACCACCCGCATCGTCGCCGGTGTC 
GGCGTGCCGCAGATCTCCGCCATCGCCAACGTCGCCGCCGCCCTCGAGGGCACCGGCGTACCGCTGATCGCC 
GACGGCGGCATCCGCTTCTCCGGCGACCTGGCCAAGGCCATGGTCGCCGGCGCCTACTGCGTGATGATGGGC 
TCGATGTTCGCCGGTACCGAGGAAGCGCCGGGCGAGATCGAGCTGTTCCAGGGCCGTTCCTACAAGTCCTAC 
CGCGGCATGGGTTCGCTGGGCGCCATGTCCGGCTCCCAGGGCTCGTCCGACCGCTACTTCCAGGACGCCTCC 
GCCGGCGCCGAGAAGCTGGTGCCGGAAGGCATCGAGGGTCGCGTGCCGTACAAGGGTGCCTTGTCCGCCATC 
GTCCACCAACTGATGGGCGGCCTGCGCGCCGCCATGGGCTACACCGGCAGCGCCGACATCCAGCAGATGCGC 
ACGCAGCCGCAGTTCGTCCGGATCACCGGCGCGGGCATGGCCGAGTCCCATGTCCACGACGTCCAGATCACC 
AAGGAAGCCCCCAACTACCGGGTTGGTTGA