ViewGene
Locus Name:
GeneID:
Location:

GeneID:4047
TrivialName: PA14_19630
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_19630
PAO1 Ortholog Locus:PA3438
Sequence Length:561
Protein Length:186
Start: 1695275
Stop: 1694715
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06826.1|AE004764_12 (AE004764) GTP cyclohydrolase I precursor [Pseudomonas aeruginosa PAO1]
Identities = 186/186 (100%), Positives = 186/186 (100%)
Sequence:
ATGAACCCAGCACTTTCCCAGCATTACCGGGAGATCCTCGTCGGTCTCGGCGAAGACCCGCAGCGCGAAGGC
CTGCTCGACACCCCGAAGCGCGCGGCCAAGGCCATGCAGTACCTCTGCCACGGCTATGGCCAGACCCTGGAG
GAAATCGTCAACGGCGCGCTGTTCGCCTCGGACAACGATGAAATGGTCATCGTCCGCGACATCGAGCTGTAC
TCCCTGTGCGAACACCACCTCCTGCCCTTCATCGGCAAGGCTCATGTGGCGTACATTCCCACCGGCAAGGTG
CTCGGCCTGTCGAAGGTGGCGCGGATCGTCGACATGTTCGCCCGCCGCCTGCAGATCCAGGAGAACCTCACC
CGGCAGATCGCCGAGGCGGTCCGCCAGGTGACCAGCGCCGCCGGCGTGGCGGTAGTGATCGAGGCCCAGCAC
ATGTGCATGATGATGCGCGGGGTGGAGAAGCAGAACTCGCAGATGTTCACCTCGGTGATGCTCGGCGCGTTC
CGCGACTCGAACACCACCCGCCAGGAATTTCTGCAATTGATCGGAAGGAGCAAGTGA
Translation:
MNPALSQHYREILVGLGEDPQREGLLDTPKRAAKAMQYLCHGYGQTLEEIVNGALFASDNDEMVIVRDIELY
SLCEHHLLPFIGKAHVAYIPTGKVLGLSKVARIVDMFARRLQIQENLTRQIAEAVRQVTSAAGVAVVIEAQH
MCMMMRGVEKQNSQMFTSVMLGAFRDSNTTRQEFLQLIGRSK*
AnnotationID:4054GeneID:4047
AnnotatorUID: diggins
Modification Date/Time: 2005-04-18 18:06:03
Gene Name:folE1
Confidence Code:2
GeneProduct:GTP cyclohydrolase I precursor
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:cd00642,pfam01227,COG0302
Secondary Functional Category(ies):
EC Number:3.5.4.16
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO54709.1| (AE016860) GTP cyclohydrolase I [Pseudomonas syringae pv. tomato
           str. DC3000]
          Length = 187

 Score =  322 bits (824), Expect = 9e-88
 Identities = 159/186 (85%), Positives = 178/186 (95%)

>gb|AAO90329.1| (AE016962) GTP cyclohydrolase I [Coxiella burnetii RSA 493]
          Length = 184

 Score =  247 bits (631), Expect = 2e-65
 Identities = 118/182 (64%), Positives = 147/182 (80%)






 
Structural Features:
cd00642, GTP_cyclohydro1, GTP cyclohydrolase I (GTP-CH-I) 
catalyzes the conversion of GTP into dihydroneopterin triphosphate.
CD-Length = 185 residues,  98.4% aligned
Score =  257 bits (658), Expect = 6e-70
Identities = 107/182 (58%), Positives = 137/182 (75%)

pfam01227, GTP_cyclohydroI, GTP cyclohydrolase I. 
CD-Length = 101 residues, 100.0% aligned
Score =  116 bits (292), Expect = 2e-27
Identities = 50/105 (47%), Positives = 60/105 (57%), Gaps = 4/105 (3%)

COG0302, FolE, GTP cyclohydrolase I [Coenzyme metabolism]
CD-Length = 195 residues,  92.8% aligned
Score =  281 bits (720), Expect = 4e-77
Identities = 112/181 (61%), Positives = 134/181 (74%)







   
Genomic Context:






   
Comment:


















    ReferenceID:8096




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25239




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32130




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4047_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:4047
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6288
                           PA3438_tr
                           translation of PA3438
                           186
                           99.99
                           99.99
                           0
                           941.0
     

     
     
173197
                           gb|AAG06826.1|AE004764_12
                           (AE004764) GTP cyclohydrolase I precursor [Pseudomonas aeruginosa PAO1]
                           186
                           99.99
                           99.99
                           0
                           941.0
     

     
     
173198
                           gb|AAO54709.1|
                           (AE016860) GTP cyclohydrolase I [Pseudomonas syringae pv. tomato str. DC3000]
                           187
                           85.02
                           95.18
                           1
                           824.0
     

     
     
173199
                           gb|AAN68124.1|AE016444_4
                           (AE016783) GTP cyclohydrolase I [Pseudomonas putida KT2440]
                           186
                           79.56
                           91.39
                           0
                           781.0
     

     
     
6289
                           PA1674_tr
                           translation of PA1674
                           186
                           78.49
                           85.48
                           5
                           743.0
     

     






      

          
GC ORFID: 47049How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3438Glimmer Score: 

          
Start: 3258657Stop: 3259217

          
Length: 561


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3438 translation of PA3438Homolog Bit Score 367.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene5034 (ORF: BLASTX 325.0), t_PA1674 (ORF: BLASTX 292.0)

          
GC ORF Sequence

           
ATGAACCCAGCACTTTCCCAGCATTACCGGGAGATCCTCGTCGGTCTCGGCGAAGACCCGCAGCGCGAAGGC 
CTGCTCGACACCCCGAAGCGCGCGGCCAAGGCCATGCAGTACCTCTGCCACGGCTATGGCCAGACCCTGGAG 
GAAATCGTCAACGGCGCGCTGTTCGCCTCGGACAACGATGAAATGGTCATCGTCCGCGACATCGAGCTGTAC 
TCCCTGTGCGAACACCACCTCCTGCCCTTCATCGGCAAGGCTCATGTGGCGTACATTCCCACCGGCAAGGTG 
CTCGGCCTGTCGAAGGTGGCGCGGATCGTCGACATGTTCGCCCGCCGCCTGCAGATCCAGGAGAACCTCACC 
CGGCAGATCGCCGAGGCGGTCCGCCAGGTGACCAGCGCCGCCGGCGTGGCGGTAGTGATCGAGGCCCAGCAC 
ATGTGCATGATGATGCGCGGGGTGGAGAAGCAGAACTCGCAGATGTTCACCTCGGTGATGCTCGGCGCGTTC 
CGCGACTCGAACACCACCCGCCAGGAATTTCTGCAATTGATCGGAAGGAGCAAGTGA