ViewGene
Locus Name:
GeneID:
Location:

GeneID:2413
TrivialName: PA14_17900
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_17900
PAO1 Ortholog Locus:PA3587
Sequence Length:921
Protein Length:306
Start: 1538266
Stop: 1537346
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06975.1|AE004779_7 (AE004779) transcriptional regulator MetR [Pseudomonas aeruginosa PAO1]
Identities = 305/306 (99%), Positives = 306/306 (100%)
Sequence:
ATGCTCGAACTTCGCCACCTCAAGACCCTGCACGCGCTGCGCGAAGCCGACAGCCTGGTGGAAGCCGCCGAG
CGCCTGCACCTTACCCAGTCGGCGCTGTCGCACCAGTTCAAGGAACTGGAAGAGCGCCTGGGCATGCAGTTG
TTCGTGCGCAAGACCAAGCCGGTACGCTTCACCAGCGCCGGGCTGCGCCTGCTGCAACTGGCCGACTCGCTG
CTGCCCCAACTGCGCACCGCCGAGCGCGACCTGGCACGGCTCGCCGGCGGTACCGCCGGGCGCCTGCACATG
GCCATCGAATGCCACAGTTGCTTCCAGTGGCTGATGCCGACCATCGACCAGTTCCGCGACGCCTGGCCGGAA
GTCGAACTGGACCTGGCCTCGGGCTTCTCCTTCGCGCCGCTGCCGGCCCTGGCCCGCGGCGACCTCGACCTG
GTGGTAACCGCCGACCCGATCGAGTTGCCCGGCATCACCTACGTGCCACTGTTCACCTACGAAGCGCTGCTG
GCGGTGGCCAACCAGCATGCCCTGGCTGGCCGGCCGTACGTCGTCCCGGAGGATCTGGAGCGGGAAACCCTG
ATCACCTATCCGGTGGAACGCGACCGTCTCGACGTCTTCACCCGCTTCCTCGACCCCGCCGACGTGGAGCCG
GCGCAGGTGCGCATAGCCGAGCTGACCGTGATGATGATGCAACTGGTGGCCTCCGGTCGCGGCGTCTGCTGC
CTGCCGAACTGGGCCCTGCACGAGTACAGCTCGCGCGGCTACGTGACGGCCCGGCGCCTCGGTGAAAAGGGC
CTGTACTGCACGCTCTTCGCCGCCATCCGCACGGACATGTTCGATGCGCCATTCATGCGCGACTTCCTGCTC
ACCGCCAAGGACACCTCCTTCGCCACCCTCGAAGGGGTCAGCGCCGCCAAGGGCTGA
Translation:
MLELRHLKTLHALREADSLVEAAERLHLTQSALSHQFKELEERLGMQLFVRKTKPVRFTSAGLRLLQLADSL
LPQLRTAERDLARLAGGTAGRLHMAIECHSCFQWLMPTIDQFRDAWPEVELDLASGFSFAPLPALARGDLDL
VVTADPIELPGITYVPLFTYEALLAVANQHALAGRPYVVPEDLERETLITYPVERDRLDVFTRFLDPADVEP
AQVRIAELTVMMMQLVASGRGVCCLPNWALHEYSSRGYVTARRLGEKGLYCTLFAAIRTDMFDAPFMRDFLL
TAKDTSFATLEGVSAAKG*
AnnotationID:2421GeneID:2413
AnnotatorUID: diggins
Modification Date/Time: 2005-04-20 11:11:22
Gene Name:metR
Confidence Code:2
GeneProduct:transcriptional regulator MetR
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:transcriptional activator MetR
Functional Category Confidence Code:5
COGs:COG0583,pfam03466
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO57636.1| (AE016871) transcriptional activator MetR [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 305

 Score =  548 bits (1411), Expect = e-155
 Identities = 267/305 (87%), Positives = 292/305 (95%)

>emb|CAE42819.1| (BX640418) transcriptional regulatory protein [Bordetella
           pertussis]
          Length = 309

 Score =  383 bits (984), Expect = e-106
 Identities = 187/306 (61%), Positives = 235/306 (76%)

>gb|AAN83183.1|AE016769_298 (AE016769) Transcriptional activator protein metR [Escherichia coli
           CFT073]
          Length = 317

 Score =  267 bits (683), Expect = 5e-71
 Identities = 140/305 (45%), Positives = 197/305 (64%), Gaps = 5/305 (1%)






 
Structural Features:
COG0583, LysR, Transcriptional regulator [Transcription]
CD-Length = 297 residues,  95.6% aligned
Score =  135 bits (340), Expect = 1e-32
Identities = 101/288 (35%), Positives = 136/288 (47%), Gaps = 6/288 (2%)

pfam03466, LysR_substrate, LysR substrate binding domain. 
The structure of this domain is known and is similar 
to the periplasmic binding proteins.
CD-Length = 209 residues,  96.2% aligned
Score =  116 bits (291), Expect = 8e-27
Identities = 62/201 (30%), Positives = 89/201 (44%)






   
Genomic Context:






   
Comment:


















    ReferenceID:4829




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21975




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31956




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2413_cdd.html


    		




 
URL:

















    ReferenceID:34163




  
Author/Investigator(s):
        Plamann LS, Stauffer GV.





  
Title:
        Nucleotide sequence of the Salmonella typhimurium metR gene and the metR-metE control region.




  
PubMed:
        3040668


MedLine:
        




    
Source:
J Bacteriol. 1987 Sep;169(9):3932-7.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=3040668









           
Homologs By Global Alignment 

           

       



     
Gene ID:2413
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
4064
                           PA3587_tr
                           translation of PA3587
                           306
                           99.67
                           99.99
                           0
                           1565.0
     

     
     
121928
                           gb|AAG06975.1|AE004779_7
                           (AE004779) transcriptional regulator MetR [Pseudomonas aeruginosa PAO1]
                           306
                           99.67
                           99.99
                           0
                           1565.0
     

     
     
121929
                           gb|AAO57636.1|
                           (AE016871) transcriptional activator MetR [Pseudomonas syringae pv. tomato str. DC3000]
                           306
                           87.25
                           95.42
                           1
                           1411.0
     

     
     
121930
                           gb|AAN66688.1|AE016297_2
                           (AE016778) transcriptional activator MetR [Pseudomonas putida KT2440]
                           306
                           84.96
                           94.44
                           1
                           1381.0
     

     
     
121931
                           gb|AAN68304.1|AE016464_8
                           (AE016784) transcriptional activator MetR [Pseudomonas putida KT2440]
                           309
                           76.05
                           88.34
                           3
                           1275.0
     

     






      

          
GC ORFID: 45415How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3587Glimmer Score: 

          
Start: 3415670Stop: 3416590

          
Length: 921


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3587 translation of PA3587Homolog Bit Score 607.0

          
Other Homologs:  psyr_15may02_Scaffold5_revised_gene6138 (ORF: BLASTX 548.0), t_PA3587 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCTCGAACTTCGCCACCTCAAGACCCTGCACGCGCTGCGCGAAGCCGACAGCCTGGTGGAAGCCGCCGAG 
CGCCTGCACCTTACCCAGTCGGCGCTGTCGCACCAGTTCAAGGAACTGGAAGAGCGCCTGGGCATGCAGTTG 
TTCGTGCGCAAGACCAAGCCGGTACGCTTCACCAGCGCCGGGCTGCGCCTGCTGCAACTGGCCGACTCGCTG 
CTGCCCCAACTGCGCACCGCCGAGCGCGACCTGGCACGGCTCGCCGGCGGTACCGCCGGGCGCCTGCACATG 
GCCATCGAATGCCACAGTTGCTTCCAGTGGCTGATGCCGACCATCGACCAGTTCCGCGACGCCTGGCCGGAA 
GTCGAACTGGACCTGGCCTCGGGCTTCTCCTTCGCGCCGCTGCCGGCCCTGGCCCGCGGCGACCTCGACCTG 
GTGGTAACCGCCGACCCGATCGAGTTGCCCGGCATCACCTACGTGCCACTGTTCACCTACGAAGCGCTGCTG 
GCGGTGGCCAACCAGCATGCCCTGGCTGGCCGGCCGTACGTCGTCCCGGAGGATCTGGAGCGGGAAACCCTG 
ATCACCTATCCGGTGGAACGCGACCGTCTCGACGTCTTCACCCGCTTCCTCGACCCCGCCGACGTGGAGCCG 
GCGCAGGTGCGCATAGCCGAGCTGACCGTGATGATGATGCAACTGGTGGCCTCCGGTCGCGGCGTCTGCTGC 
CTGCCGAACTGGGCCCTGCACGAGTACAGCTCGCGCGGCTACGTGACGGCCCGGCGCCTCGGTGAAAAGGGC 
CTGTACTGCACGCTCTTCGCCGCCATCCGCACGGACATGTTCGATGCGCCATTCATGCGCGACTTCCTGCTC 
ACCGCCAAGGACACCTCCTTCGCCACCCTCGAAGGGGTCAGCGCCGCCAAGGGCTGA