ViewGene
Locus Name:
GeneID:
Location:

GeneID:24
TrivialName: PA14_15740
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_15740
PAO1 Ortholog Locus:PA3763
Sequence Length:3897
Protein Length:1298
Start: 1338564
Stop: 1342460
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07150.1|AE004795_2 (AE004795) phosphoribosylformylglycinamidine synthase [Pseudomonas aeruginosa PAO1]
Identities = 1297/1298 (99%), Positives = 1298/1298 (100%)
Sequence:
ATGCTGATCCTGCGCGGCGCTCCCGCCCTTTCCGCTTTCCGCCACGGCAAACTGCTCGAGCAACTGACCCAG
CACGTACCTGCCGTTACCGGGCTGTACGCTGAGTTCGCGCATTTCGCCGACGTCACCGGCGCGCTCACCGCC
GACGAGGAGCAGGTGCTGGCGCGGCTGCTGAAATACGGCCCGAGCGTGCCGGTGCAGGAGCCCAGCGGCCGG
CTGTTCCTGGTGGTGCCGCGCTTCGGCACCATCTCGCCGTGGTCGAGCAAGGCCTCCGACATCGCCCGCAAC
TGCGGCCTGGCGAAGATCGACCGGCTGGAGCGCGGCATTGCCTACTATGTGCAGGGCGAACTGTCTGAGAGC
GACGCCCAACAGGTCGCCGCCCGCCTGCATGACCGCATGACCCAACTGGTGCTGGACCGCCTGGAAGGCGCC
GCCGAGCTGTTCAGCCATGCGCAGCCCCGCCCGCTCACCGCCGTCGACGTGCTTGGCGGCGGTCGCGCCGCG
CTGGAGAAGGCCAACGTCGAGCTGGGCCTGGCCCTGGCCGAGGACGAGATCGACTACCTGCTGAAGAGCTTC
GGCGAACTGGGGCGCAACCCGCACGACGTCGAGCTGATGATGTTCGCCCAGGCCAACTCCGAGCATTGCCGG
CACAAGATCTTCAATGCCAGTTGGGACATCGACGGGCAGGCCCAGGACAAGAGCCTGTTCGGCATGATCAAG
AACACCTACGAGATGAACCGCGAAGGCGTGCTGTCCGCATACAAGGACAACGCCGCGGTCATCGTCGGCCAT
GTCGCCGGGCGTTTCTTCCCCGATCCGCAGACCCGCGAATACGCCGCCAGCCGCGAGCCGGTGCAGATCCTG
ATGAAGGTGGAGACCCACAACCACCCGACCGCCATCGCGCCGTTCCCCGGTGCCTCCACCGGTTCCGGCGGC
GAGATCCGCGACGAGGGCGCCACCGGCCGCGGCGCCAAGCCGAAGGCCGGCCTGACCGGCTTCACCGTGTCC
AACCTGCAGATCCCCGGTTTCGAACAGCCCTGGGAAGTGCCCTACGGCAAGCCCGAGCGCATCGTCACCGCG
CTGGACATCATGGTCGAGGGCCCGCTGGGCGGCGCCGCGTTCAACAACGAGTTCGGCCGTCCGGCGCTGACC
GGCTACTTCCGTACCTTCGAGCAGAAGATCGCTACCCCTCACGGCGAGGAAGTGCGCGGCTACCACAAGCCG
ATCATGCTCGCCGGCGGCATGGGCAACATTCGCGACGAACACGTGCAGAAGGGCGAGATCAGCGTCGGCGCC
AAGCTCATCGTCCTTGGCGGCCCGGCCATGCTGATCGGCCTGGGCGGCGGCGCCGCCTCTTCGATGGCCACC
GGCGCCAGCTCCGCCGACCTCGACTTCGCCTCGGTGCAGCGCGACAACCCGGAAATGGAGCGACGTTGCCAG
GAAGTGATCGACCGCTGCTGGCAGCTCGGCGAGCGCAACCCGATCAGCTTCATCCATGACGTCGGTGCCGGC
GGCCTGTCCAACGCCCTGCCGGAACTGATCAACGACGGCGGCCGCGGCGGTCGCTTCGAGCTGCGCGCGGTG
CCCAACGACGAGCCGGGCATGAGCCCGCTGGAAATCTGGTGCAACGAGTCGCAGGAGCGCTACGTGCTGTCG
GTGGACGCCGCCGACTTCGAGACCTTCAAGGCCATCTGCGAGCGCGAGCGCTGCCCGTTCGCGGTGGTCGGC
GAGGCCATCGAGCAGCGCCAGCTGACCGTCGCCGACAGCCATTTCGACAACAAGCCGGTGGACATGCCGCTG
GAAGTCCTGCTCGGCAAGGCGCCGCGCATGCACCGCGCGGTCACCCGCGAGGCCGAGCTGGGTGACGATTTC
GACGCCGCCGGGCTGGAGCTGCAGGAAAGCGTCGAGCGCGTCCTGCGCCATCCCGCCGTGGCCAGCAAGAGC
TTCCTGATCACCATCGGCGACCGCACCATCACCGGGCTGGTGGCCCGCGACCAGATGGTCGGGCCCTGGCAG
GTGCCGGTGGCCGACTGCGCCGTCACCGCCACCAGCTTCGACGTCTACACCGGCGAGGCCATGGCGATGGGC
GAGCGCACCCCGCTGGCGCTGCTGGACGCCCCGGCTTCCGGACGCATGGCCATCGGCGAGACGGTCACCAAC
CTGGCTGCCGCGCGTATCGGCAAGCTGTCCGACATCAAGCTTTCCGCCAACTGGATGGCCGCCGCCGGCCAC
CCCGGCGAGGACGCGCGCCTGTATGACACGGTCAAGGCCGTGGGCATGGAACTGTGTCCGGAACTGGGCATC
ACCATCCCGGTGGGCAAGGACTCGATGTCCATGAAGACCCGCTGGCAGGACAATGGCGAGGACAAGAGCGTC
ACTTCTCCGGTCTCGCTGATCGTCACCGGCTTCGCTCCGGTCGCCGACGTGCGCCAGAGCCTGACCCCGCAA
CTGCGCCTGGACAAGGGCGAGACCGACCTGATCCTGATCGATCTCGGCCGCGGCAAGAACCGTCTCGGCGGC
TCGATCCTGGCCCAGGTCCACGGCAAGCTCGGCCGCGCCGTGCCGGACGTCGACGACGCCGAGGACCTGAAA
GCCTTCTTCGCGGTGATCCAGGGGCTCAATGCCGACGGCCATATCCTCGCCTACCACGACCGTTCCGACGGC
GGCCTGATCACCAGCGTGCTGGAGATGGCCTTCGCCGGTCACTGCGGCGTCGAGCTGAACCTCGATGCCCTG
GCCGATAGCCGCGAAGAGCTGGCGGCCGTGTTGTTCAGCGAGGAACTGGGCGCGGTGATCCAGGTTCGCGAG
GGCGCCACTCCGGAAGTCCTCGCGCAGTTCAGCGCCGCCGGTCTCGACGACTGCGTGGCGGTGATCGGCCAG
CCGGTCAACGGCTACGAGATCAACCTGAACTACAACGGCGAGACCGTCTACAGCGCCCAGCGCCGCATCCTG
CAACGCATCTGGAGCGAGACCAGCTACCAGATCCAGCGTCTGCGCGACAACGCCGACTGCGCCGAGCAGGAG
TTCGACGCGTTGCTGGACGAAGACAACCCCGGGCTGTCGATCAAGCTCAGCTACGACGTCAACGATGACATC
GCCGCGCCCTACATCAAGAAGGGCGTGCGGCCGAAAGTGGCGATCCTCCGCGAGCAGGGCGTCAACGGCCAG
GTGGAGATGGCCGCGGCGTTCGACCGCGCCGGCTTCGCCGCGATCGACGTGCACATGAGCGACATCCTCGCC
GGGCGGGTCGACCTGGACGCCTTCAAGGGCCTGGTGGCCTGCGGTGGCTTCTCCTACGGCGACGTGCTCGGC
GCCGGCGAGGGCTGGGCCAAGTCGATCCTCTTCAACGCCCGCGCCCGCGACGGCTTCCAGGCCTTCTTCGCG
CGCAAGGACAGCTTCGCCCTCGGCGTCTGCAACGGCTGCCAGATGATGTCCAACCTGCACGAGCTGATTCCC
GGCACCGAGTTCTGGCCGCACTTCGTGCGCAACCGTTCCGAGCAGTTCGAGGCGCGGGTGGCGATGGTCCAG
GTGCAGGAGTCGTCGTCGATCTTCCTGCAGGGCATGGCCGGTTCGCGCCTGCCGATCGCCATCGCCCATGGC
GAAGGCCATGCGGAGTTCGAGTCGGAGGAAGCGTTGCTCGAGGCCGACCTTTCCGGCTGCGTGTCGCTGCGT
TTCGTCGACAACCACGGCAAGGTCACCGAAGCCTACCCGGCCAACCCCAACGGGTCGCCGCGCGGCATCACC
GGGCTGAGCAGCCGCGACGGCCGGGTCACCATCATGATGCCGCACCCCGAGCGGGTGTTCCGCGCCGTGCAG
AATTCCTGGCGTCCGGACGACTGGCAGGAAGACGGCGGCTGGCTGCGCATGTTCCGCAACGCCCGGGTCTGG
GTGGACTGA
Translation:
MLILRGAPALSAFRHGKLLEQLTQHVPAVTGLYAEFAHFADVTGALTADEEQVLARLLKYGPSVPVQEPSGR
LFLVVPRFGTISPWSSKASDIARNCGLAKIDRLERGIAYYVQGELSESDAQQVAARLHDRMTQLVLDRLEGA
AELFSHAQPRPLTAVDVLGGGRAALEKANVELGLALAEDEIDYLLKSFGELGRNPHDVELMMFAQANSEHCR
HKIFNASWDIDGQAQDKSLFGMIKNTYEMNREGVLSAYKDNAAVIVGHVAGRFFPDPQTREYAASREPVQIL
MKVETHNHPTAIAPFPGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKPERIVTA
LDIMVEGPLGGAAFNNEFGRPALTGYFRTFEQKIATPHGEEVRGYHKPIMLAGGMGNIRDEHVQKGEISVGA
KLIVLGGPAMLIGLGGGAASSMATGASSADLDFASVQRDNPEMERRCQEVIDRCWQLGERNPISFIHDVGAG
GLSNALPELINDGGRGGRFELRAVPNDEPGMSPLEIWCNESQERYVLSVDAADFETFKAICERERCPFAVVG
EAIEQRQLTVADSHFDNKPVDMPLEVLLGKAPRMHRAVTREAELGDDFDAAGLELQESVERVLRHPAVASKS
FLITIGDRTITGLVARDQMVGPWQVPVADCAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAIGETVTN
LAAARIGKLSDIKLSANWMAAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMSMKTRWQDNGEDKSV
TSPVSLIVTGFAPVADVRQSLTPQLRLDKGETDLILIDLGRGKNRLGGSILAQVHGKLGRAVPDVDDAEDLK
AFFAVIQGLNADGHILAYHDRSDGGLITSVLEMAFAGHCGVELNLDALADSREELAAVLFSEELGAVIQVRE
GATPEVLAQFSAAGLDDCVAVIGQPVNGYEINLNYNGETVYSAQRRILQRIWSETSYQIQRLRDNADCAEQE
FDALLDEDNPGLSIKLSYDVNDDIAAPYIKKGVRPKVAILREQGVNGQVEMAAAFDRAGFAAIDVHMSDILA
GRVDLDAFKGLVACGGFSYGDVLGAGEGWAKSILFNARARDGFQAFFARKDSFALGVCNGCQMMSNLHELIP
GTEFWPHFVRNRSEQFEARVAMVQVQESSSIFLQGMAGSRLPIAIAHGEGHAEFESEEALLEADLSGCVSLR
FVDNHGKVTEAYPANPNGSPRGITGLSSRDGRVTIMMPHPERVFRAVQNSWRPDDWQEDGGWLRMFRNARVW
VD*
AnnotationID:34GeneID:24
AnnotatorUID: diggins
Modification Date/Time: 2005-04-22 11:11:24
Gene Name:purL
Confidence Code:2
GeneProduct:phosphoribosylformylglycinamidine synthase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0046,COG0047
Secondary Functional Category(ies):
EC Number:6.3.5.3
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66662.1|AE016294_4 (AE016777) phosphoribosylformylglycinamidine synthase [Pseudomonas
            putida KT2440]
          Length = 1299

 Score = 2261 bits (5859), Expect = 0.0
 Identities = 1105/1299 (85%), Positives = 1210/1299 (93%), Gaps = 1/1299 (0%)

>gb|AAN81529.1|AE016764_211 (AE016764) Phosphoribosylformylglycinamidine synthase [Escherichia
            coli CFT073]
          Length = 1295

 Score = 1713 bits (4437), Expect = 0.0
 Identities = 845/1295 (65%), Positives = 1013/1295 (78%), Gaps = 6/1295 (0%)








 
Structural Features:
COG0046, PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, 
synthetase domain 
[Nucleotide transport and metabolism]
CD-Length = 743 residues,  98.7% aligned
Score =  775 bits (2002), Expect = 0.0
Identities = 322/826 (38%), Positives = 409/826 (49%), Gaps = 105/826 (12%)

COG0047, PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, 
glutamine amidotransferase domain 
[Nucleotide transport and metabolism]
CD-Length = 231 residues,  99.6% aligned
Score =  272 bits (698), Expect = 3e-73
Identities = 107/258 (41%), Positives = 141/258 (54%), Gaps = 29/258 (11%)






   
Genomic Context:






   
Comment:


















    ReferenceID:51




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17193




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31794




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:24_cdd.html


    		




 
URL:

















    ReferenceID:34269




  
Author/Investigator(s):
        Schendel FJ, Mueller E, Stubbe J, Shiau A, Smith JM.





  
Title:
        Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization.




  
PubMed:
        2659070


MedLine:
        




    
Source:
Biochemistry. 1989 Mar 21;28(6):2459-71.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2659070

















    ReferenceID:34270




  
Author/Investigator(s):
        Sampei G, Mizobuchi K.





  
Title:
        The organization of the purL gene encoding 5'-phosphoribosylformylglycinamide amidotransferase of Escherichia coli.




  
PubMed:
        2531746


MedLine:
        




    
Source:
J Biol Chem. 1989 Dec 15;264(35):21230-8.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2531746









           
Homologs By Global Alignment 

           

       



     
Gene ID:24
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
51
                           PA3763_tr
                           translation of PA3763
                           1298
                           99.92
                           99.99
                           0
                           6715.0
     

     
     
10967
                           gb|AAG07150.1|AE004795_2
                           (AE004795) phosphoribosylformylglycinamidine synthase [Pseudomonas aeruginosa PAO1]
                           1298
                           99.92
                           99.99
                           0
                           6715.0
     

     
     
10968
                           gb|AAN66662.1|AE016294_4
                           (AE016777) phosphoribosylformylglycinamidine synthase [Pseudomonas putida KT2440]
                           1299
                           85.06
                           93.14
                           1
                           5861.0
     

     
     
10969
                           gb|AAO54980.1|
                           (AE016861) phosphoribosylformylglycinamidine synthase [Pseudomonas syringae pv. tomato str. DC3000]
                           1298
                           84.59
                           92.75
                           0
                           5843.0
     

     
     
10970
                           gb|AAF94031.1|
                           (AE004171) phosphoribosylformylglycinamidine synthase [Vibrio cholerae O1 biovar eltor str. N16961]
                           1300
                           66.69
                           79.38
                           5
                           4563.0
     

     






      

          
GC ORFID: 43026How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3763Glimmer Score: 

          
Start: 3615373Stop: 3611477

          
Length: 3897


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3763 translation of PA3763Homolog Bit Score 2591.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4548 (ORF: BLASTX 2267.0), t_PA3763 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCTGATCCTGCGCGGCGCTCCCGCCCTTTCCGCTTTCCGCCACGGCAAACTGCTCGAGCAACTGACCCAG 
CACGTACCTGCCGTTACCGGGCTGTACGCTGAGTTCGCGCATTTCGCCGACGTCACCGGCGCGCTCACCGCC 
GACGAGGAGCAGGTGCTGGCGCGGCTGCTGAAATACGGCCCGAGCGTGCCGGTGCAGGAGCCCAGCGGCCGG 
CTGTTCCTGGTGGTGCCGCGCTTCGGCACCATCTCGCCGTGGTCGAGCAAGGCCTCCGACATCGCCCGCAAC 
TGCGGCCTGGCGAAGATCGACCGGCTGGAGCGCGGCATTGCCTACTATGTGCAGGGCGAACTGTCTGAGAGC 
GACGCCCAACAGGTCGCCGCCCGCCTGCATGACCGCATGACCCAACTGGTGCTGGACCGCCTGGAAGGCGCC 
GCCGAGCTGTTCAGCCATGCGCAGCCCCGCCCGCTCACCGCCGTCGACGTGCTTGGCGGCGGTCGCGCCGCG 
CTGGAGAAGGCCAACGTCGAGCTGGGCCTGGCCCTGGCCGAGGACGAGATCGACTACCTGCTGAAGAGCTTC 
GGCGAACTGGGGCGCAACCCGCACGACGTCGAGCTGATGATGTTCGCCCAGGCCAACTCCGAGCATTGCCGG 
CACAAGATCTTCAATGCCAGTTGGGACATCGACGGGCAGGCCCAGGACAAGAGCCTGTTCGGCATGATCAAG 
AACACCTACGAGATGAACCGCGAAGGCGTGCTGTCCGCATACAAGGACAACGCCGCGGTCATCGTCGGCCAT 
GTCGCCGGGCGTTTCTTCCCCGATCCGCAGACCCGCGAATACGCCGCCAGCCGCGAGCCGGTGCAGATCCTG 
ATGAAGGTGGAGACCCACAACCACCCGACCGCCATCGCGCCGTTCCCCGGTGCCTCCACCGGTTCCGGCGGC 
GAGATCCGCGACGAGGGCGCCACCGGCCGCGGCGCCAAGCCGAAGGCCGGCCTGACCGGCTTCACCGTGTCC 
AACCTGCAGATCCCCGGTTTCGAACAGCCCTGGGAAGTGCCCTACGGCAAGCCCGAGCGCATCGTCACCGCG 
CTGGACATCATGGTCGAGGGCCCGCTGGGCGGCGCCGCGTTCAACAACGAGTTCGGCCGTCCGGCGCTGACC 
GGCTACTTCCGTACCTTCGAGCAGAAGATCGCTACCCCTCACGGCGAGGAAGTGCGCGGCTACCACAAGCCG 
ATCATGCTCGCCGGCGGCATGGGCAACATTCGCGACGAACACGTGCAGAAGGGCGAGATCAGCGTCGGCGCC 
AAGCTCATCGTCCTTGGCGGCCCGGCCATGCTGATCGGCCTGGGCGGCGGCGCCGCCTCTTCGATGGCCACC 
GGCGCCAGCTCCGCCGACCTCGACTTCGCCTCGGTGCAGCGCGACAACCCGGAAATGGAGCGACGTTGCCAG 
GAAGTGATCGACCGCTGCTGGCAGCTCGGCGAGCGCAACCCGATCAGCTTCATCCATGACGTCGGTGCCGGC 
GGCCTGTCCAACGCCCTGCCGGAACTGATCAACGACGGCGGCCGCGGCGGTCGCTTCGAGCTGCGCGCGGTG 
CCCAACGACGAGCCGGGCATGAGCCCGCTGGAAATCTGGTGCAACGAGTCGCAGGAGCGCTACGTGCTGTCG 
GTGGACGCCGCCGACTTCGAGACCTTCAAGGCCATCTGCGAGCGCGAGCGCTGCCCGTTCGCGGTGGTCGGC 
GAGGCCATCGAGCAGCGCCAGCTGACCGTCGCCGACAGCCATTTCGACAACAAGCCGGTGGACATGCCGCTG 
GAAGTCCTGCTCGGCAAGGCGCCGCGCATGCACCGCGCGGTCACCCGCGAGGCCGAGCTGGGTGACGATTTC 
GACGCCGCCGGGCTGGAGCTGCAGGAAAGCGTCGAGCGCGTCCTGCGCCATCCCGCCGTGGCCAGCAAGAGC 
TTCCTGATCACCATCGGCGACCGCACCATCACCGGGCTGGTGGCCCGCGACCAGATGGTCGGGCCCTGGCAG 
GTGCCGGTGGCCGACTGCGCCGTCACCGCCACCAGCTTCGACGTCTACACCGGCGAGGCCATGGCGATGGGC 
GAGCGCACCCCGCTGGCGCTGCTGGACGCCCCGGCTTCCGGACGCATGGCCATCGGCGAGACGGTCACCAAC 
CTGGCTGCCGCGCGTATCGGCAAGCTGTCCGACATCAAGCTTTCCGCCAACTGGATGGCCGCCGCCGGCCAC 
CCCGGCGAGGACGCGCGCCTGTATGACACGGTCAAGGCCGTGGGCATGGAACTGTGTCCGGAACTGGGCATC 
ACCATCCCGGTGGGCAAGGACTCGATGTCCATGAAGACCCGCTGGCAGGACAATGGCGAGGACAAGAGCGTC 
ACTTCTCCGGTCTCGCTGATCGTCACCGGCTTCGCTCCGGTCGCCGACGTGCGCCAGAGCCTGACCCCGCAA 
CTGCGCCTGGACAAGGGCGAGACCGACCTGATCCTGATCGATCTCGGCCGCGGCAAGAACCGTCTCGGCGGC 
TCGATCCTGGCCCAGGTCCACGGCAAGCTCGGCCGCGCCGTGCCGGACGTCGACGACGCCGAGGACCTGAAA 
GCCTTCTTCGCGGTGATCCAGGGGCTCAATGCCGACGGCCATATCCTCGCCTACCACGACCGTTCCGACGGC 
GGCCTGATCACCAGCGTGCTGGAGATGGCCTTCGCCGGTCACTGCGGCGTCGAGCTGAACCTCGATGCCCTG 
GCCGATAGCCGCGAAGAGCTGGCGGCCGTGTTGTTCAGCGAGGAACTGGGCGCGGTGATCCAGGTTCGCGAG 
GGCGCCACTCCGGAAGTCCTCGCGCAGTTCAGCGCCGCCGGTCTCGACGACTGCGTGGCGGTGATCGGCCAG 
CCGGTCAACGGCTACGAGATCAACCTGAACTACAACGGCGAGACCGTCTACAGCGCCCAGCGCCGCATCCTG 
CAACGCATCTGGAGCGAGACCAGCTACCAGATCCAGCGTCTGCGCGACAACGCCGACTGCGCCGAGCAGGAG 
TTCGACGCGTTGCTGGACGAAGACAACCCCGGGCTGTCGATCAAGCTCAGCTACGACGTCAACGATGACATC 
GCCGCGCCCTACATCAAGAAGGGCGTGCGGCCGAAAGTGGCGATCCTCCGCGAGCAGGGCGTCAACGGCCAG 
GTGGAGATGGCCGCGGCGTTCGACCGCGCCGGCTTCGCCGCGATCGACGTGCACATGAGCGACATCCTCGCC 
GGGCGGGTCGACCTGGACGCCTTCAAGGGCCTGGTGGCCTGCGGTGGCTTCTCCTACGGCGACGTGCTCGGC 
GCCGGCGAGGGCTGGGCCAAGTCGATCCTCTTCAACGCCCGCGCCCGCGACGGCTTCCAGGCCTTCTTCGCG 
CGCAAGGACAGCTTCGCCCTCGGCGTCTGCAACGGCTGCCAGATGATGTCCAACCTGCACGAGCTGATTCCC 
GGCACCGAGTTCTGGCCGCACTTCGTGCGCAACCGTTCCGAGCAGTTCGAGGCGCGGGTGGCGATGGTCCAG 
GTGCAGGAGTCGTCGTCGATCTTCCTGCAGGGCATGGCCGGTTCGCGCCTGCCGATCGCCATCGCCCATGGC 
GAAGGCCATGCGGAGTTCGAGTCGGAGGAAGCGTTGCTCGAGGCCGACCTTTCCGGCTGCGTGTCGCTGCGT 
TTCGTCGACAACCACGGCAAGGTCACCGAAGCCTACCCGGCCAACCCCAACGGGTCGCCGCGCGGCATCACC 
GGGCTGAGCAGCCGCGACGGCCGGGTCACCATCATGATGCCGCACCCCGAGCGGGTGTTCCGCGCCGTGCAG 
AATTCCTGGCGTCCGGACGACTGGCAGGAAGACGGCGGCTGGCTGCGCATGTTCCGCAACGCCCGGGTCTGG 
GTGGACTGA