ViewGene
Locus Name:
GeneID:
Location:

GeneID:2264
TrivialName: PA14_17270
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_17270
PAO1 Ortholog Locus:PA3639
Sequence Length:951
Protein Length:316
Start: 1483003
Stop: 1483953
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07027.1|AE004783_12 (AE004783) acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit) [Pseudomonas aeruginosa PAO1]
Identities = 316/316 (100%), Positives = 316/316 (100%)
Sequence:
ATGAACCCGAACTTTCTTGATTTCGAACAGCCGATCGCCGACCTGCAAGCCAAGATCGAAGAGCTGCGCCTG
GTGGGCAACGACAATGCGCTGAACATCAGCGACGAAATCTCGCGTCTGCAGGACAAGAGCAAGGCGCTCACC
GAAAACATCTTCGGCAATCTGTCCAGTTGGCAGATCGCCCAGCTCGCGCGCCATCCCAAGCGTCCCTATACC
CTCGACTACATCGGCTACCTGTTCAGCGATTTCGAGGAACTGCACGGCGACCGGCATTTCGCCGACGACCCG
GCGATCGTCGGCGGCGTTGCCCGCCTCGACGGTTCCCCGGTGATGGTCATCGGCCACCAGAAAGGCCGCGAA
GTCCGTGAGAAGGTCCGGCGCAACTTCGGCATGCCGCGTCCGGAAGGCTATCGCAAGGCCTGCCGCCTGATG
GAAATGGCCGAACGCTTCAAGATGCCGATCCTGACCTTCATCGACACGCCCGGCGCCTACCCGGGCATCGAT
GCCGAGGAACGCGGCCAGAGCGAGGCGATCGCCTGGAACCTGCGGGTGATGGCGCGACTGAAGACGCCGATC
ATCGCCACCGTGATCGGCGAGGGCGGTTCCGGCGGCGCGCTGGCCATCGGTGTCTGCGACCAGTTGAACATG
CTGCAATACTCCACCTATTCGGTGATCTCGCCGGAAGGCTGCGCCTCCATCCTCTGGAAGACCGCCGAGAAG
GCGCCGGAAGCCGCCGAGGCCATGGGTATCACCGCCGAGCGCCTGAAAGGCCTGGGCATCGTCGACAAGGTC
ATCGACGAACCGCTGGGCGGCGCCCATCGCGATCCGGCGAGCATGGCCGAATCGATCCGTGGCGAACTGCTG
GCGCAACTGAAGATGCTCCAGGGCCTGGAAATGGGTGAGTTGCTGGAGCGTCGTTACGACCGCCTGATGAGC
TACGGCGCGCCGTAA
Translation:
MNPNFLDFEQPIADLQAKIEELRLVGNDNALNISDEISRLQDKSKALTENIFGNLSSWQIAQLARHPKRPYT
LDYIGYLFSDFEELHGDRHFADDPAIVGGVARLDGSPVMVIGHQKGREVREKVRRNFGMPRPEGYRKACRLM
EMAERFKMPILTFIDTPGAYPGIDAEERGQSEAIAWNLRVMARLKTPIIATVIGEGGSGGALAIGVCDQLNM
LQYSTYSVISPEGCASILWKTAEKAPEAAEAMGITAERLKGLGIVDKVIDEPLGGAHRDPASMAESIRGELL
AQLKMLQGLEMGELLERRYDRLMSYGAP*
AnnotationID:2272GeneID:2264
AnnotatorUID: danlee
Modification Date/Time: 2006-01-31 14:02:41
Gene Name:accA
Confidence Code:2
GeneProduct:acetyl-CoA carboxylase, carboxyl transferase, alpha subunit
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0825,pfam03255
Secondary Functional Category(ies):
EC Number:6.4.1.2
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO55070.1| (AE016861) acetyl-CoA carboxylase, carboxyl transferase, alpha
           subunit [Pseudomonas syringae pv. tomato str. DC3000]
          Length = 315

 Score =  553 bits (1424), Expect = e-157
 Identities = 272/314 (86%), Positives = 292/314 (92%)

>gb|AAC73296.1| (AE000127) acetylCoA carboxylase, carboxytransferase component,
           alpha subunit [Escherichia coli K12]
          Length = 319

 Score =  441 bits (1134), Expect = e-123
 Identities = 219/317 (69%), Positives = 259/317 (81%), Gaps = 3/317 (0%)








 
Structural Features:
COG0825, AccA, Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]
CD-Length = 317 residues,  99.4% aligned
Score =  503 bits (1297), Expect = 2e-143
Identities = 213/315 (67%), Positives = 252/315 (80%)

pfam03255, ACCA, Acetyl co-enzyme A carboxylase carboxyltransferase 
alpha subunit.
CD-Length = 145 residues, 100.0% aligned
Score =  225 bits (574), Expect = 1e-59
Identities = 87/145 (60%), Positives = 109/145 (75%)






   
Genomic Context:






   
Comment:


















    ReferenceID:4531




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21677




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31904




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2264_cdd.html


    		




 
URL:

















    ReferenceID:34195




  
Author/Investigator(s):
        Best EA, Knauf VC.





  
Title:
        Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.




  
PubMed:
        7693652


MedLine:
        




    
Source:
J Bacteriol. 1993 Nov;175(21):6881-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7693652

















    ReferenceID:34196




  
Author/Investigator(s):
        Kiatpapan P, Kobayashi H, Sakaguchi M, Ono H, Yamashita M, Kaneko Y, Murooka Y.





  
Title:
        Molecular characterization of Lactobacillus plantarum genes for beta-ketoacyl-acyl carrier protein synthase III (fabH) and acetyl coenzyme A carboxylase (accBCDA), which are essential for fatty acid biosynthesis.




  
PubMed:
        11133475


MedLine:
        




    
Source:
Appl Environ Microbiol. 2001 Jan;67(1):426-33.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11133475

















    ReferenceID:34197




  
Author/Investigator(s):
        Kimura Y, Miyake R, Tokumasu Y, Sato M.





  
Title:
        Molecular cloning and characterization of two genes for the biotin carboxylase and carboxyltransferase subunits of acetyl coenzyme A carboxylase in Myxococcus xanthus.




  
PubMed:
        10986250


MedLine:
        




    
Source:
J Bacteriol. 2000 Oct;182(19):5462-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10986250









           
Homologs By Global Alignment 

           

       



     
Gene ID:2264
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3852
                           PA3639_tr
                           translation of PA3639
                           316
                           99.99
                           99.99
                           0
                           1629.0
     

     
     
118145
                           gb|AAG07027.1|AE004783_12
                           (AE004783) acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit) [Pseudomonas aeruginosa PAO1]
                           316
                           99.99
                           99.99
                           0
                           1629.0
     

     
     
118146
                           gb|AAO55070.1|
                           (AE016861) acetyl-CoA carboxylase, carboxyl transferase, alpha subunit [Pseudomonas syringae pv. tomato str. DC3000]
                           316
                           86.07
                           92.40
                           1
                           1423.0
     

     
     
118147
                           gb|AAN67228.1|AE016350_1
                           (AE016779) acetyl-CoA carboxylase, carboxyl transferase, alpha subunit [Pseudomonas putida KT2440]
                           316
                           86.07
                           92.08
                           1
                           1417.0
     

     
     
118148
                           gb|AAM86669.1|AE013912_13
                           (AE013912) acetyl CoA carboxylase, carboxytransferase component, alpha subunit [Yersinia pestis KIM]
                           319
                           70.53
                           82.44
                           3
                           1154.0
     

     






      

          
GC ORFID: 45266How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3639Glimmer Score: 

          
Start: 3470934Stop: 3469984

          
Length: 951


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA3639 translation of PA3639Homolog Bit Score 632.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4636 (ORF: BLASTX 557.0), t_PA3639 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACCCGAACTTTCTTGATTTCGAACAGCCGATCGCCGACCTGCAAGCCAAGATCGAAGAGCTGCGCCTG 
GTGGGCAACGACAATGCGCTGAACATCAGCGACGAAATCTCGCGTCTGCAGGACAAGAGCAAGGCGCTCACC 
GAAAACATCTTCGGCAATCTGTCCAGTTGGCAGATCGCCCAGCTCGCGCGCCATCCCAAGCGTCCCTATACC 
CTCGACTACATCGGCTACCTGTTCAGCGATTTCGAGGAACTGCACGGCGACCGGCATTTCGCCGACGACCCG 
GCGATCGTCGGCGGCGTTGCCCGCCTCGACGGTTCCCCGGTGATGGTCATCGGCCACCAGAAAGGCCGCGAA 
GTCCGTGAGAAGGTCCGGCGCAACTTCGGCATGCCGCGTCCGGAAGGCTATCGCAAGGCCTGCCGCCTGATG 
GAAATGGCCGAACGCTTCAAGATGCCGATCCTGACCTTCATCGACACGCCCGGCGCCTACCCGGGCATCGAT 
GCCGAGGAACGCGGCCAGAGCGAGGCGATCGCCTGGAACCTGCGGGTGATGGCGCGACTGAAGACGCCGATC 
ATCGCCACCGTGATCGGCGAGGGCGGTTCCGGCGGCGCGCTGGCCATCGGTGTCTGCGACCAGTTGAACATG 
CTGCAATACTCCACCTATTCGGTGATCTCGCCGGAAGGCTGCGCCTCCATCCTCTGGAAGACCGCCGAGAAG 
GCGCCGGAAGCCGCCGAGGCCATGGGTATCACCGCCGAGCGCCTGAAAGGCCTGGGCATCGTCGACAAGGTC 
ATCGACGAACCGCTGGGCGGCGCCCATCGCGATCCGGCGAGCATGGCCGAATCGATCCGTGGCGAACTGCTG 
GCGCAACTGAAGATGCTCCAGGGCCTGGAAATGGGTGAGTTGCTGGAGCGTCGTTACGACCGCCTGATGAGC 
TACGGCGCGCCGTAA