ViewGene
Locus Name:
GeneID:
Location:

GeneID:2222
TrivialName: PA14_18110
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_18110
PAO1 Ortholog Locus:PA3571
Sequence Length:924
Protein Length:307
Start: 1554397
Stop: 1553474
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06959.1|AE004778_3 (AE004778) transcriptional regulator MmsR [Pseudomonas aeruginosa PAO1]
Identities = 306/307 (99%), Positives = 307/307 (100%)
Sequence:
ATGGACTATATTGCGGAGCCGGCTACCGACATGTCGCACACCTCCGACTGGCCCCTGCCGGCCGACAGCCTG
CGCTTGCCGATCCCGGCGGCGCTGCTGGAGAAACTGGCGGTCCACCCGCTCAGCCGCGACCTCTACCCCACC
TCCCTGGGCCACTACCGGCGCGCCCGCGACCACCGCATGAGCCGCGAGCGCCATGACGAGCACCTGCTGATC
TATTGCAGCGAAGGCCAGGGCCTGTTGCGCGTGCGCGAGGGCGAGGCCTGGCGCGAATACCGGGTCGGCAGC
GGCGACCTGCTCTGGCTGCCGCCGGGCATGGCCCACGACTACGCCGCCGACGACCGCCAACCCTGGACCATC
TTTTGGACCCACCTGCGCGGCGACAGCGCCACCTGGCTGCAACACAGCGCCGGCTACCGCGACACCCCGCTG
CGCCATTGGGGCCTGCAACACGCCCTGCTCGGCGGCTTCGAGCAACTGCTGGAGGTGCGCCACAGCGGCTAC
CGCTTCCAGCACTTCCTGCTCGCCGCCAGCCGCATGCGCAGCCTGCTCTGCCAGCTACCGCTGCTGCGCCCG
CTGCGCGAGGGCAGCCTGGACCTCGACGGGCTGCACGCCTACATGCGTGAACACCTGCATGCGCGCCTCGAA
CTGGAACGCCTGGCGGCCTTCTGCAACCTGTCGAAGTTCCATTTCGTCAGTCGCTACAAGGCGATCACCGGC
CGTACGCCTATCCAGCACTTCCTGCACCTGAAGATCGAGTACGCCTGCCAGTTGCTGGACAGCAGCGACCAG
AGCGTGGCCCGGGTCGGCCAGGCGGTCGGCTACGACGACAGCTACTACTTCTCGCGCCTGTTCAGCAAGGTC
ATGGGTTTGTCGCCGAGCGCCTACCGACAGCGGGTAAGGCAGGGCGAGGGAGGAGCCTGA
Translation:
MDYIAEPATDMSHTSDWPLPADSLRLPIPAALLEKLAVHPLSRDLYPTSLGHYRRARDHRMSRERHDEHLLI
YCSEGQGLLRVREGEAWREYRVGSGDLLWLPPGMAHDYAADDRQPWTIFWTHLRGDSATWLQHSAGYRDTPL
RHWGLQHALLGGFEQLLEVRHSGYRFQHFLLAASRMRSLLCQLPLLRPLREGSLDLDGLHAYMREHLHARLE
LERLAAFCNLSKFHFVSRYKAITGRTPIQHFLHLKIEYACQLLDSSDQSVARVGQAVGYDDSYYFSRLFSKV
MGLSPSAYRQRVRQGEGGA*
AnnotationID:2230GeneID:2222
AnnotatorUID: diggins
Modification Date/Time: 2005-04-20 06:06:16
Gene Name:mmsR
Confidence Code:1
GeneProduct: transcriptional regulator MmsR
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG2207,smart00342
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO79501.1| (AE016945) transcriptional regulator [Bacteroides thetaiotaomicron
           VPI-5482]
          Length = 295

 Score =  154 bits (390), Expect = 5e-37
 Identities = 91/287 (31%), Positives = 155/287 (54%), Gaps = 23/287 (8%)








 
Structural Features:
COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription]
CD-Length = 127 residues,  96.1% aligned
Score = 81.5 bits (200), Expect = 2e-16
Identities = 41/122 (33%), Positives = 63/122 (51%)

smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein
CD-Length = 84 residues, 100.0% aligned
Score = 78.7 bits (194), Expect = 2e-15
Identities = 33/84 (39%), Positives = 45/84 (53%)








   
Genomic Context:






   
Comment:


















    ReferenceID:4447




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:21593




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31969




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:2222_cdd.html


    		




 
URL:

















    ReferenceID:34156




  
Author/Investigator(s):
        Steele MI, Lorenz D, Hatter K, Park A, Sokatch JR.





  
Title:
        Characterization of the mmsAB operon of Pseudomonas aeruginosa PAO encoding methylmalonate-semialdehyde dehydrogenase and 3-hydroxyisobutyrate dehydrogenase.




  
PubMed:
        1339433


MedLine:
        




    
Source:
J Biol Chem. 1992 Jul 5;267(19):13585-92.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1339433









           
Homologs By Global Alignment 

           

       



     
Gene ID:2222
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
3773
                           PA3571_tr
                           translation of PA3571
                           307
                           99.67
                           99.99
                           0
                           1646.0
     

     
     
115985
                           gb|AAG06959.1|AE004778_3
                           (AE004778) transcriptional regulator MmsR [Pseudomonas aeruginosa PAO1]
                           307
                           99.67
                           99.99
                           0
                           1646.0
     

     
     
115986
                           gb|AAA25890.1|
                           (M84911) member of the AraC/XylS family of transcriptional regulators [Pseudomonas aeruginosa]
                           307
                           99.34
                           99.99
                           0
                           1643.0
     

     
     
3774
                           PA0748_tr
                           translation of PA0748
                           353
                           30.87
                           41.07
                           93
                           352.0
     

     
     
115987
                           gb|AAG04137.1|AE004510_1
                           (AE004510) still frameshift probable transcriptional regulator [Pseudomonas aeruginosa PAO1]
                           353
                           30.87
                           41.07
                           93
                           352.0
     

     






      

          
GC ORFID: 45224How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3571Glimmer Score: 

          
Start: 3399539Stop: 3400462

          
Length: 924


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3571 translation of PA3571Homolog Bit Score 638.0

          
Other Homologs:  t_PA0748 (ORF: BLASTX 137.0), t_PA3571 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGGACTATATTGCGGAGCCGGCTACCGACATGTCGCACACCTCCGACTGGCCCCTGCCGGCCGACAGCCTG 
CGCTTGCCGATCCCGGCGGCGCTGCTGGAGAAACTGGCGGTCCACCCGCTCAGCCGCGACCTCTACCCCACC 
TCCCTGGGCCACTACCGGCGCGCCCGCGACCACCGCATGAGCCGCGAGCGCCATGACGAGCACCTGCTGATC 
TATTGCAGCGAAGGCCAGGGCCTGTTGCGCGTGCGCGAGGGCGAGGCCTGGCGCGAATACCGGGTCGGCAGC 
GGCGACCTGCTCTGGCTGCCGCCGGGCATGGCCCACGACTACGCCGCCGACGACCGCCAACCCTGGACCATC 
TTTTGGACCCACCTGCGCGGCGACAGCGCCACCTGGCTGCAACACAGCGCCGGCTACCGCGACACCCCGCTG 
CGCCATTGGGGCCTGCAACACGCCCTGCTCGGCGGCTTCGAGCAACTGCTGGAGGTGCGCCACAGCGGCTAC 
CGCTTCCAGCACTTCCTGCTCGCCGCCAGCCGCATGCGCAGCCTGCTCTGCCAGCTACCGCTGCTGCGCCCG 
CTGCGCGAGGGCAGCCTGGACCTCGACGGGCTGCACGCCTACATGCGTGAACACCTGCATGCGCGCCTCGAA 
CTGGAACGCCTGGCGGCCTTCTGCAACCTGTCGAAGTTCCATTTCGTCAGTCGCTACAAGGCGATCACCGGC 
CGTACGCCTATCCAGCACTTCCTGCACCTGAAGATCGAGTACGCCTGCCAGTTGCTGGACAGCAGCGACCAG 
AGCGTGGCCCGGGTCGGCCAGGCGGTCGGCTACGACGACAGCTACTACTTCTCGCGCCTGTTCAGCAAGGTC 
ATGGGTTTGTCGCCGAGCGCCTACCGACAGCGGGTAAGGCAGGGCGAGGGAGGAGCCTGA