ViewGene
Locus Name:
GeneID:
Location:

GeneID:982
TrivialName: PA14_48240
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_48240
PAO1 Ortholog Locus:PA1238
Sequence Length:1449
Protein Length:482
Start: 4294069
Stop: 4295517
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04627.1|AE004553_4 (AE004553) probable outer membrane component of multidrug efflux pump [Pseudomonas aeruginosa PAO1]
Identities = 476/482 (98%), Positives = 478/482 (99%)
Sequence:
ATGCCGCTTGCCAGTCATCTGCGTTGCGTGGCGCTGGCGCTGGGGATCTCCACCGCGCTGGGCTGCGCGAAC
CGCAACCAACCCGCGCCACGCGCGGAAAGCCTCGACCCTGGCCTGTCGAGGGTGGCGGGAACCCGCGGCGAC
GCGCTGCCCGCCCAGTGGTGGACGCTCTACCAGGACCCTGGGCTGAACCACCTGGTGGCCGCCGCGCTGCGC
CACAACCGCGACCTGGCCGCAGCCGATGCCCATGCCCGCGCGCTCCTCGGCCATCTGCGCGGCGCACAGGGC
GAACGCTGGCCACGGACCGAGGTCGGCTATGGCTACCAGTATGGGCGCGACGGCGACGACCAGACCCTCGCC
GAAGCCACCGACGAGGAGCTGCGCAGCCAGTGGAAACACACCGCCCGCCTCGACCTGTCCTACCAGTTGGAC
CTGTGGGGCGAAGTCCGCGCCCGCATCGCCGCGGCGAAGGCGGATGCCGAAGCGGCGCAAGCGGCGCGCGAC
CTGCTCAGGGTCAGCGTGGCCAGCCAGACCACCCTCGCCTACGTCCGCGCCTGCGCCCTGGCGCGACGGGCA
GAGGTACAACGCCGATCGGTCGGCCTGCTCGACGCGAGCCTGGCGCTGAGCGAACGCCAGCTCGCCGCCGGC
CTTTCCAGCGAGCTGCAGCGACGCCGGCTGCTGGCCTTGCGCGAGCGGACCCGCGCCGCGCTGCCGATGCTC
GAGGCGCGGCGGCGCGCGGCACTCTACGAACTGGCGCTGCTCAGCGGGCGCTCGCCGCGCCAGTTGGACGCT
CCTGCCGCGACCTGCGCCGGCATACCGCAACTGCGCCGTGCCCTGCCCACCGGCGACGGCTGGAGCCTGCTG
GCGCGCCGCCCGGACGTCCGCGCGGCCGAGCGCCGGCTCGCCGCCGCCGACGCCCGGCGCGCGCTGGCCGAA
GCCGAGCTGTACCCGCGCATCAGCTTCGCCGTCGGCGCCGAAACCTCCGCAGCGACCCTCGCCGGCCTCGGC
GGCAGCGGCGCGCTAGCCTACGCGGCCGGTCCTCTGCTGGGCTGGCGCTTCCCCAACCGGGAAAGCGCGCGA
GGCCGCCTGGACAGCGCAGCGGCAGAGCGCGACGCCGCTCTGGCGCGCTTCGACGGAGCGGTGCTCGGCGCC
CTGCGCGAGGTCGAGCGTGCCTTGGCGCTGTATGCCGGCGAGCGCCAGCGGCGTGCCGACCTCCAGCGTGCC
CTCGACGAGCAGCGCCACGCCTACCGGTTGGCGCGCAGCAACTATCGCGCCGGCGCCCTCGATGCCCTCGAG
CTGCTCGACAGTCAACGCAGCCTGGTCGCCGACCGGGCGCGCCTGGTCGACGCCGAGATGCGCGTCGCCGAG
CGCCAGGTCGAACTGTTCCGGGCTCTCGGCGGCGGCTGGCAAGCCGCTCCCAGCCCCTCCCACCAGGATAAC
GGACAATGA
Translation:
MPLASHLRCVALALGISTALGCANRNQPAPRAESLDPGLSRVAGTRGDALPAQWWTLYQDPGLNHLVAAALR
HNRDLAAADAHARALLGHLRGAQGERWPRTEVGYGYQYGRDGDDQTLAEATDEELRSQWKHTARLDLSYQLD
LWGEVRARIAAAKADAEAAQAARDLLRVSVASQTTLAYVRACALARRAEVQRRSVGLLDASLALSERQLAAG
LSSELQRRRLLALRERTRAALPMLEARRRAALYELALLSGRSPRQLDAPAATCAGIPQLRRALPTGDGWSLL
ARRPDVRAAERRLAAADARRALAEAELYPRISFAVGAETSAATLAGLGGSGALAYAAGPLLGWRFPNRESAR
GRLDSAAAERDAALARFDGAVLGALREVERALALYAGERQRRADLQRALDEQRHAYRLARSNYRAGALDALE
LLDSQRSLVADRARLVDAEMRVAERQVELFRALGGGWQAAPSPSHQDNGQ*
AnnotationID:991GeneID:982
AnnotatorUID: diggins
Modification Date/Time: 2005-02-22 09:09:26
Gene Name:
Confidence Code:3
GeneProduct:putative outer membrane component of multidrug efflux pump
Cell Localization:()
Synonyms:PA1238
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(3) Antibiotic resistance and susceptibility
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1538,pfam02321
Secondary Functional Category(ies):membrane protein
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67683.1|AE016398_7 (AE016781) multidrug efflux MFS outer membrane protein, putative
           [Pseudomonas putida KT2440]
          Length = 473

 Score =  410 bits (1054), Expect = e-114
 Identities = 222/463 (47%), Positives = 293/463 (63%), Gaps = 6/463 (1%)








 
Structural Features:
COG1538, TolC, Outer membrane protein 
[Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]
CD-Length = 457 residues,  93.0% aligned
Score =  168 bits (425), Expect = 2e-42
Identities = 141/430 (32%), Positives = 205/430 (47%), Gaps = 5/430 (1%)

pfam02321, OEP, Outer membrane efflux protein. 
CD-Length = 188 residues,  96.8% aligned
Score = 70.4 bits (172), Expect = 4e-13
Identities = 52/182 (28%), Positives = 85/182 (46%), Gaps = 1/182 (0%)






   
Genomic Context:






   
Comment:


















    ReferenceID:1967




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19109




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37548




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:982_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:982
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1756
                           PA1238_tr
                           translation of PA1238
                           482
                           98.75
                           99.17
                           0
                           2383.0
     

     
     
61775
                           gb|AAG04627.1|AE004553_4
                           (AE004553) probable outer membrane component of multidrug efflux pump [Pseudomonas aeruginosa PAO1]
                           482
                           98.75
                           99.17
                           0
                           2383.0
     

     
     
61776
                           gb|AAN67683.1|AE016398_7
                           (AE016781) multidrug efflux MFS outer membrane protein, putative [Pseudomonas putida KT2440]
                           489
                           46.01
                           60.53
                           23
                           1059.0
     

     
     
61777
                           emb|CAE33576.1|
                           (BX640446) probable outer membrane efflux protein [Bordetella bronchiseptica] [Bordetella bronchiseptica RB50]
                           493
                           38.33
                           52.53
                           31
                           757.0
     

     
     
61778
                           emb|CAE36945.1|
                           (BX640428) probable outer membrane efflux protein [Bordetella parapertussis]
                           493
                           38.33
                           52.53
                           31
                           757.0
     

     






      

          
GC ORFID: 43984How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1238Glimmer Score: 

          
Start: 659839Stop: 658391

          
Length: 1449


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1238 translation of PA1238Homolog Bit Score 922.0

          
Other Homologs:  t_PA1238 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCCGCTTGCCAGTCATCTGCGTTGCGTGGCGCTGGCGCTGGGGATCTCCACCGCGCTGGGCTGCGCGAAC 
CGCAACCAACCCGCGCCACGCGCGGAAAGCCTCGACCCTGGCCTGTCGAGGGTGGCGGGAACCCGCGGCGAC 
GCGCTGCCCGCCCAGTGGTGGACGCTCTACCAGGACCCTGGGCTGAACCACCTGGTGGCCGCCGCGCTGCGC 
CACAACCGCGACCTGGCCGCAGCCGATGCCCATGCCCGCGCGCTCCTCGGCCATCTGCGCGGCGCACAGGGC 
GAACGCTGGCCACGGACCGAGGTCGGCTATGGCTACCAGTATGGGCGCGACGGCGACGACCAGACCCTCGCC 
GAAGCCACCGACGAGGAGCTGCGCAGCCAGTGGAAACACACCGCCCGCCTCGACCTGTCCTACCAGTTGGAC 
CTGTGGGGCGAAGTCCGCGCCCGCATCGCCGCGGCGAAGGCGGATGCCGAAGCGGCGCAAGCGGCGCGCGAC 
CTGCTCAGGGTCAGCGTGGCCAGCCAGACCACCCTCGCCTACGTCCGCGCCTGCGCCCTGGCGCGACGGGCA 
GAGGTACAACGCCGATCGGTCGGCCTGCTCGACGCGAGCCTGGCGCTGAGCGAACGCCAGCTCGCCGCCGGC 
CTTTCCAGCGAGCTGCAGCGACGCCGGCTGCTGGCCTTGCGCGAGCGGACCCGCGCCGCGCTGCCGATGCTC 
GAGGCGCGGCGGCGCGCGGCACTCTACGAACTGGCGCTGCTCAGCGGGCGCTCGCCGCGCCAGTTGGACGCT 
CCTGCCGCGACCTGCGCCGGCATACCGCAACTGCGCCGTGCCCTGCCCACCGGCGACGGCTGGAGCCTGCTG 
GCGCGCCGCCCGGACGTCCGCGCGGCCGAGCGCCGGCTCGCCGCCGCCGACGCCCGGCGCGCGCTGGCCGAA 
GCCGAGCTGTACCCGCGCATCAGCTTCGCCGTCGGCGCCGAAACCTCCGCAGCGACCCTCGCCGGCCTCGGC 
GGCAGCGGCGCGCTAGCCTACGCGGCCGGTCCTCTGCTGGGCTGGCGCTTCCCCAACCGGGAAAGCGCGCGA 
GGCCGCCTGGACAGCGCAGCGGCAGAGCGCGACGCCGCTCTGGCGCGCTTCGACGGAGCGGTGCTCGGCGCC 
CTGCGCGAGGTCGAGCGTGCCTTGGCGCTGTATGCCGGCGAGCGCCAGCGGCGTGCCGACCTCCAGCGTGCC 
CTCGACGAGCAGCGCCACGCCTACCGGTTGGCGCGCAGCAACTATCGCGCCGGCGCCCTCGATGCCCTCGAG 
CTGCTCGACAGTCAACGCAGCCTGGTCGCCGACCGGGCGCGCCTGGTCGACGCCGAGATGCGCGTCGCCGAG 
CGCCAGGTCGAACTGTTCCGGGCTCTCGGCGGCGGCTGGCAAGCCGCTCCCAGCCCCTCCCACCAGGATAAC 
GGACAATGA