ViewGene
Locus Name:
GeneID:
Location:

GeneID:974
TrivialName: PA14_06070
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_06070
PAO1 Ortholog Locus:PA0464
Sequence Length:1425
Protein Length:474
Start: 536757
Stop: 538181
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG03853.1|AE004484_5 (AE004484) two-component sensor CreC [Pseudomonas aeruginosa PAO1]
Identities = 473/474 (99%), Positives = 473/474 (99%)
Sequence:
ATGCCGCTCGGCGTTCGGATCTTCCTGGTCTACTTCCTGTTCGTCGGTCTCACCGGCTACTTCGTGCTGAGC
ACGGTGATGGACGAAGTGCGCCCCGGCGTGCGCCAGTCCACCGAGGAAACCCTGGTGGACACCGCCAACCTG
CTCGCCGAGATCCTCCGCCAGGACGTGAAGAACGGCACCCTGGCACAGAGCGACCTGCCGGAGATGCTCGAG
GACTACGGCAAGCGGGTGCCGCAGGCGGATATCTGGGGCTTGCGCAAGGAGGCGGTGAACCACCGCATCTAC
GTCACCGACGCCAGCGGCAAGGTGCTGCTGGACTCCGCCGGGGTGGCCGTCGGCCAGGACTATTCGCGCTGG
AACGACGTCTACCTAACCCTCCGTGGCCAGTACGGCGCGCGCTCCAGCCGCGAAGACCCGGACGACCCGGAT
TCCTCGGTGATGTACGTGGCGGCGCCGATCAAGGATGCCGGGAAGATCATCGGGGTGGTTTCGGTGGCCAAG
CCGAACAGCAGCCTGCAACCTTACATCGACCGCTCGCAGCGGCGCCTGGCCTGGCTCGGTGCCGGGCTGATC
GCCCTCGGGCTGCTGGTCGGCGGCCTGCTCTCCTGGTGGCTCAGCGGCGCGCTGCGGCGCCTCACCCAGTAC
GCCCAGGCGGTCAGCGAGGGGCGCCGCGCCGAGCTGCCGCGCTATCGCGGCGGCGAGATGGCGCAACTGGCC
GACGCGGTGGAGCGCATGCGCACGCAATTGGAGGGCAAGGACTACGTCGAGCGCTACGTGCATACCCTGACC
CACGAATTGAAGAGCCCGCTGGCGGCGATCCGTGGCGCCGCCGAGTTGCTCGACGGCGAGATGCCGGCCGAA
CAGCGGGCGCGCTTCGTCGGCAACATCGCCGGCGAGAGCGAGCGCCTGCAACAACTGATCGAGCGCCTGCTG
AGCCTGGCCCAGGTGGAGCAGCGGCAAGGCCTGGAGGAGGTCGGCAAGGTCGACCTGCGGGAGATCGCCGCG
TCCCTGCTGGAAGGCCAGGCGGCGCGTATCCAGCGCCAGCGATTGCGGGTGGAGAATCGCCTGGAAGGTCCC
TGCGAGGTTCGCGGCGAGCAGTTCCTGCTGCGCCAGGCGCTGGCCAACCTGCTCGACAACGCCCTCGACTTT
ACCCCGCCCGGCGGCATCCTTCGCCTGCTCGCCGAGGCCGACGGCGAGGGTATCGCCCTGCGCCTGTTCAAC
CAGGGGCCGGCGATTCCCGACTACGCCCTGGCGCGCCTCACCGAACGCTTCTACTCGCTGCCGCGCCCGGCC
AGCGGGCGCAAGAGCACCGGGCTGGGACTGAACTTCGTCGCCGAGGTGGCGCAACTGCATGGCGGCCGGTTG
CAGGTCGGCAATCGCGACGACGGCGTCGAGGCGCTGCTCTGGCTGCCGCGCGGCTGA
Translation:
MPLGVRIFLVYFLFVGLTGYFVLSTVMDEVRPGVRQSTEETLVDTANLLAEILRQDVKNGTLAQSDLPEMLE
DYGKRVPQADIWGLRKEAVNHRIYVTDASGKVLLDSAGVAVGQDYSRWNDVYLTLRGQYGARSSREDPDDPD
SSVMYVAAPIKDAGKIIGVVSVAKPNSSLQPYIDRSQRRLAWLGAGLIALGLLVGGLLSWWLSGALRRLTQY
AQAVSEGRRAELPRYRGGEMAQLADAVERMRTQLEGKDYVERYVHTLTHELKSPLAAIRGAAELLDGEMPAE
QRARFVGNIAGESERLQQLIERLLSLAQVEQRQGLEEVGKVDLREIAASLLEGQAARIQRQRLRVENRLEGP
CEVRGEQFLLRQALANLLDNALDFTPPGGILRLLAEADGEGIALRLFNQGPAIPDYALARLTERFYSLPRPA
SGRKSTGLGLNFVAEVAQLHGGRLQVGNRDDGVEALLWLPRG*
AnnotationID:983GeneID:974
AnnotatorUID: diggins
Modification Date/Time: 2005-03-28 04:04:28
Gene Name:creC
Confidence Code:2
GeneProduct:two-component sensor CreC; catabolite repression sensor kinase for PhoB
Cell Localization:()
Synonyms:blrB
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(28) Two-component regulatory systems
Alternate Gene Product Name:Blr Regulon Signal Sensor
Functional Category Confidence Code:5
COGs:COG0642
Secondary Functional Category(ies):transcriptional regulator
EC Number:2.7.3.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAG59579.1|AE005671_3 (AE005671) catabolite repression sensor kinase for PhoB;
           alternative sensor for pho regulon [Escherichia coli
           O157:H7 EDL933]
          Length = 474

 Score =  431 bits (1107), Expect = e-120
 Identities = 230/474 (48%), Positives = 323/474 (68%), Gaps = 4/474 (0%)

>gb|AAP19618.1| (AE016993) catabolite repression sensor kinase for PhoB,
           alternative sensor for pho regulon [Shigella flexneri 2a
           str. 2457T]
          Length = 474

 Score =  424 bits (1090), Expect = e-118
 Identities = 228/474 (48%), Positives = 321/474 (67%), Gaps = 4/474 (0%)

>gb|AAM86829.1|AE013929_2 (AE013929) catabolite repression sensor kinase for PhoB [Yersinia
           pestis KIM]
          Length = 472

 Score =  413 bits (1062), Expect = e-114
 Identities = 222/473 (46%), Positives = 309/473 (65%), Gaps = 3/473 (0%)






 
Structural Features:
COG0642, BaeS, Signal transduction histidine kinase 
[Signal transduction mechanisms]
CD-Length = 336 residues,  93.2% aligned
Score =  143 bits (359), Expect = 5e-35
Identities = 94/318 (29%), Positives = 147/318 (46%), Gaps = 9/318 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:1951




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:19093




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33792




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:974_cdd.html


    		




 
URL:

















    ReferenceID:35339




  
Author/Investigator(s):
        Niumsup P, Simm AM, Nurmahomed K, Walsh TR, Bennett PM, Avison MB.





  
Title:
        Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of beta-lactamase expression in Aeromonas spp.




  
PubMed:
        12746371


MedLine:
        




    
Source:
J Antimicrob Chemother. 2003 Jun;51(6):1351-8. Epub 2003 May 13.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12746371

















    ReferenceID:35342




  
Author/Investigator(s):
        Todd RB, Lockington RA, Kelly JM.





  
Title:
        The Aspergillus nidulans creC gene involved in carbon catabolite repression encodes a WD40 repeat protein.




  
PubMed:
        10852476


MedLine:
        




    
Source:
Mol Gen Genet. 2000 May;263(4):561-70.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10852476









           
Homologs By Global Alignment 

           

       



     
Gene ID:974
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1738
                           PA0464_tr
                           translation of PA0464
                           474
                           99.78
                           99.78
                           0
                           2388.0
     

     
     
61473
                           gb|AAG03853.1|AE004484_5
                           (AE004484) two-component sensor CreC [Pseudomonas aeruginosa PAO1]
                           474
                           99.78
                           99.78
                           0
                           2388.0
     

     
     
61478
                           emb|CAC01288.1|
                           (AJ276632) Blr Regulon Signal Sensor [Aeromonas hydrophila]
                           475
                           48.84
                           65.89
                           3
                           1106.0
     

     
     
61474
                           gb|AAG59579.1|AE005671_3
                           (AE005671) catabolite repression sensor kinase for PhoB; alternative sensor for pho regulon [Escherichia coli O157:H7 EDL933]
                           479
                           48.43
                           67.43
                           10
                           1114.0
     

     
     
61475
                           dbj|BAB38780.1|
                           (AP002569) catabolite repression sensor kinase for PhoB [Escherichia coli O157:H7]
                           479
                           48.43
                           67.43
                           10
                           1111.0
     

     






      

          
GC ORFID: 43976How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0464Glimmer Score: 

          
Start: 6338099Stop: 6339523

          
Length: 1425


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA0464 translation of PA0464Homolog Bit Score 924.0

          
Other Homologs:  t_PA0464 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCCGCTCGGCGTTCGGATCTTCCTGGTCTACTTCCTGTTCGTCGGTCTCACCGGCTACTTCGTGCTGAGC 
ACGGTGATGGACGAAGTGCGCCCCGGCGTGCGCCAGTCCACCGAGGAAACCCTGGTGGACACCGCCAACCTG 
CTCGCCGAGATCCTCCGCCAGGACGTGAAGAACGGCACCCTGGCACAGAGCGACCTGCCGGAGATGCTCGAG 
GACTACGGCAAGCGGGTGCCGCAGGCGGATATCTGGGGCTTGCGCAAGGAGGCGGTGAACCACCGCATCTAC 
GTCACCGACGCCAGCGGCAAGGTGCTGCTGGACTCCGCCGGGGTGGCCGTCGGCCAGGACTATTCGCGCTGG 
AACGACGTCTACCTAACCCTCCGTGGCCAGTACGGCGCGCGCTCCAGCCGCGAAGACCCGGACGACCCGGAT 
TCCTCGGTGATGTACGTGGCGGCGCCGATCAAGGATGCCGGGAAGATCATCGGGGTGGTTTCGGTGGCCAAG 
CCGAACAGCAGCCTGCAACCTTACATCGACCGCTCGCAGCGGCGCCTGGCCTGGCTCGGTGCCGGGCTGATC 
GCCCTCGGGCTGCTGGTCGGCGGCCTGCTCTCCTGGTGGCTCAGCGGCGCGCTGCGGCGCCTCACCCAGTAC 
GCCCAGGCGGTCAGCGAGGGGCGCCGCGCCGAGCTGCCGCGCTATCGCGGCGGCGAGATGGCGCAACTGGCC 
GACGCGGTGGAGCGCATGCGCACGCAATTGGAGGGCAAGGACTACGTCGAGCGCTACGTGCATACCCTGACC 
CACGAATTGAAGAGCCCGCTGGCGGCGATCCGTGGCGCCGCCGAGTTGCTCGACGGCGAGATGCCGGCCGAA 
CAGCGGGCGCGCTTCGTCGGCAACATCGCCGGCGAGAGCGAGCGCCTGCAACAACTGATCGAGCGCCTGCTG 
AGCCTGGCCCAGGTGGAGCAGCGGCAAGGCCTGGAGGAGGTCGGCAAGGTCGACCTGCGGGAGATCGCCGCG 
TCCCTGCTGGAAGGCCAGGCGGCGCGTATCCAGCGCCAGCGATTGCGGGTGGAGAATCGCCTGGAAGGTCCC 
TGCGAGGTTCGCGGCGAGCAGTTCCTGCTGCGCCAGGCGCTGGCCAACCTGCTCGACAACGCCCTCGACTTT 
ACCCCGCCCGGCGGCATCCTTCGCCTGCTCGCCGAGGCCGACGGCGAGGGTATCGCCCTGCGCCTGTTCAAC 
CAGGGGCCGGCGATTCCCGACTACGCCCTGGCGCGCCTCACCGAACGCTTCTACTCGCTGCCGCGCCCGGCC 
AGCGGGCGCAAGAGCACCGGGCTGGGACTGAACTTCGTCGCCGAGGTGGCGCAACTGCATGGCGGCCGGTTG 
CAGGTCGGCAATCGCGACGACGGCGTCGAGGCGCTGCTCTGGCTGCCGCGCGGCTGA