ViewGene
Locus Name:
GeneID:
Location:

GeneID:855
TrivialName: PA14_47690
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_47690
PAO1 Ortholog Locus:PA1277
Sequence Length:1473
Protein Length:490
Start: 4246354
Stop: 4244882
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04666.1|AE004557_7 (AE004557) cobyric acid synthase [Pseudomonas aeruginosa PAO1]
Identities = 489/490 (99%), Positives = 490/490 (100%)
Sequence:
ATGAGTGATCGCGGACGGACCCTGATGGTCCAGGGCACCACCTCGGACGCCGGCAAGAGCACCCTGGTGACC
GCGCTGTGCCGCTGGCTGGCCCGGCGCGGCGTCGCGGTGGTGCCGTTCAAGCCGCAGAACATGGCGCTGAAC
AGCGCGGTCACCGCCGACGGCGGCGAGATCGGCCGCGCCCAGGCGGTCCAGGCCCAGGCCTGCCGGCTGGCG
CCGCACACCGACATGAACCCGGTGCTGCTCAAGCCGAACACCGACATCGGCGCCCAGGTGATCATCCATGGC
CGCGCGGTGACCAGCATGGACGCCGCCGCCTACCACGACTACAAGCGCGTGGCGATGGAAGCGGTGCTGGCT
TCCCATGGGCGGCTCGCCGCCGCCTACCGGGTGGTGATGGTGGAGGGCGCCGGCTCGCCGGCGGAGATCAAC
CTGCGCGCCAACGACATCGCCAACATGGGCTTCGCCGAAGCGGTGGATTGCCCGGTGATCCTGGTCGCCGAT
ATCGACCGCGGCGGGGTCTTCGCCCACCTGGTCGGCACCCTGGAACTGCTCTCCGACTCGGAGCGGGAGCGG
GTCAAGGGCTTCGTCATCAATCGCTTCCGCGGCGACATCGCCCTGCTGCAACCCGGCCTCGACTGGCTGGAG
GCGCGCACCGGCAAGCCGGTGCTCGGCGTGCTGCCCTATGTCAGCGACCTGCACCTGGAGGCGGAGGACGCC
ATCGACACGCGCCAGGCGGCCAAGGTCGGGCCGCGCCTGAAGGTGGTGGTGCCGGTGCTGCCGAGGATCAGC
AACCACACCGATTTCGATCCGCTGCGCCTGCACCCCCAGGTCGAGTTGAGCTTCGTCGGCCCCGGCCAGGCG
CTGCCGTCGGCGGACCTGATCGTCCTGCCCGGCTCGAAGAGCGTGCGCGCCGACCTCGCGGCGCTGCGCGAG
CGTGGCTGGGACGAGGCGATCCTCCGTCACCTGCGCTACGGCGGTCGCCTGCTGGGGATCTGCGGCGGCCTG
CAGATGCTCGGCGAGCGCCTGCACGATCCGCTCGGCCTGGAAGGCGCGGCCGGCAGCAGCGCTGGCCTCGGC
CTGCTGGCGTTGGAAACGACCCTGGAGGCGGACAAGCAATTGCGCAACGTACAGGGCCGCCTGAGCCTGGAG
GACGCGCCGCTGTCGGGCTACGAGATCCATGCAGGGGTCACTCGTGGCGAGGCCCTGGCGCGGCCGGCGGTG
GTGCTCGACGATGGCCGCGCGGATGGTGCCCGCAGCGTCGACGGGAACGTCATGGGCACCTACCTGCACGGC
CTGTTCGAATCCACCGCGGCCTGTTCGGCGCTGCTGCGCTGGGCCGGCCTGCGCGAGGTCCAGGCGGTGGAC
TACCAGGCCTTGCGCGAACGCGACATCGAGCGGCTCGCCGACCTGGTCGAGCGCAACCTGGATACCGGGCGA
TTGCTCGCCCTCTGCGGAGAACCCCATGCGTGA
Translation:
MSDRGRTLMVQGTTSDAGKSTLVTALCRWLARRGVAVVPFKPQNMALNSAVTADGGEIGRAQAVQAQACRLA
PHTDMNPVLLKPNTDIGAQVIIHGRAVTSMDAAAYHDYKRVAMEAVLASHGRLAAAYRVVMVEGAGSPAEIN
LRANDIANMGFAEAVDCPVILVADIDRGGVFAHLVGTLELLSDSERERVKGFVINRFRGDIALLQPGLDWLE
ARTGKPVLGVLPYVSDLHLEAEDAIDTRQAAKVGPRLKVVVPVLPRISNHTDFDPLRLHPQVELSFVGPGQA
LPSADLIVLPGSKSVRADLAALRERGWDEAILRHLRYGGRLLGICGGLQMLGERLHDPLGLEGAAGSSAGLG
LLALETTLEADKQLRNVQGRLSLEDAPLSGYEIHAGVTRGEALARPAVVLDDGRADGARSVDGNVMGTYLHG
LFESTAACSALLRWAGLREVQAVDYQALRERDIERLADLVERNLDTGRLLALCGEPHA*
AnnotationID:864GeneID:855
AnnotatorUID: diggins
Modification Date/Time: 2005-02-22 18:06:08
Gene Name:cobQ
Confidence Code:2
GeneProduct:cobyric acid synthase
Cell Localization:()
Synonyms:cbiP
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1492,pfam01656
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67298.1|AE016356_6 (AE016780) cobyric acid synthase [Pseudomonas putida KT2440]
          Length = 484

 Score =  783 bits (2022), Expect = 0.0
 Identities = 393/480 (81%), Positives = 427/480 (88%)

>gb|AAO55233.1| (AE016861) cobyric acid synthase [Pseudomonas syringae pv. tomato
           str. DC3000]
          Length = 486

 Score =  782 bits (2020), Expect = 0.0
 Identities = 391/480 (81%), Positives = 426/480 (88%)

>gb|AAN54111.1|AE015548_8 (AE015548) cobyric acid synthase CobQ [Shewanella oneidensis MR-1]
          Length = 510

 Score =  577 bits (1487), Expect = e-164
 Identities = 302/503 (60%), Positives = 371/503 (73%), Gaps = 27/503 (5%)






 
Structural Features:
COG1492, CobQ, Cobyric acid synthase [Coenzyme metabolism]
CD-Length = 486 residues, 100.0% aligned
Score =  650 bits (1679), Expect = 0.0
Identities = 269/486 (55%), Positives = 320/486 (65%), Gaps = 3/486 (0%)

pfam01656, CbiA, Cobyrinic acid a,c-diamide synthase.
CD-Length = 232 residues,  99.1% aligned
Score =  209 bits (533), Expect = 5e-55
Identities = 111/230 (48%), Positives = 134/230 (58%), Gaps = 1/230 (0%)






   
Genomic Context:






   
Comment:


















    ReferenceID:1713




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:18855




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37485




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:855_cdd.html


    		




 
URL:

















    ReferenceID:38033




  
Author/Investigator(s):
        Crouzet J, Levy-Schil S, Cameron B, Cauchois L, Rigault S, Rouyez MC, Blanche F, Debussche L, Thibaut D.





  
Title:
        Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cob




  
PubMed:
        1655697


MedLine:
        




    
Source:
J Bacteriol. 1991 Oct;173(19):6074-87.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1655697









           
Homologs By Global Alignment 

           

       



     
Gene ID:855
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1539
                           PA1277_tr
                           translation of PA1277
                           490
                           99.79
                           99.99
                           0
                           2482.0
     

     
     
55446
                           gb|AAG04666.1|AE004557_7
                           (AE004557) cobyric acid synthase [Pseudomonas aeruginosa PAO1]
                           490
                           99.79
                           99.99
                           0
                           2482.0
     

     
     
55447
                           gb|AAN67298.1|AE016356_6
                           (AE016780) cobyric acid synthase [Pseudomonas putida KT2440]
                           490
                           80.20
                           87.14
                           6
                           2015.0
     

     
     
55448
                           gb|AAO55233.1|
                           (AE016861) cobyric acid synthase [Pseudomonas syringae pv. tomato str. DC3000]
                           490
                           79.79
                           86.93
                           4
                           2010.0
     

     
     
55449
                           emb|CAD16097.1|
                           (AL646069) PROBABLE COBYRIC ACID SYNTHASE PROTEIN [Ralstonia solanacearum]
                           500
                           69.20
                           77.60
                           15
                           1735.0
     

     






      

          
GC ORFID: 43857How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1277Glimmer Score: 

          
Start: 707555Stop: 709027

          
Length: 1473


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1277 translation of PA1277Homolog Bit Score 960.0

          
Other Homologs:  psyr_15may02_Scaffold5_revised_gene6473 (ORF: BLASTX 780.0), t_PA1277 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAGTGATCGCGGACGGACCCTGATGGTCCAGGGCACCACCTCGGACGCCGGCAAGAGCACCCTGGTGACC 
GCGCTGTGCCGCTGGCTGGCCCGGCGCGGCGTCGCGGTGGTGCCGTTCAAGCCGCAGAACATGGCGCTGAAC 
AGCGCGGTCACCGCCGACGGCGGCGAGATCGGCCGCGCCCAGGCGGTCCAGGCCCAGGCCTGCCGGCTGGCG 
CCGCACACCGACATGAACCCGGTGCTGCTCAAGCCGAACACCGACATCGGCGCCCAGGTGATCATCCATGGC 
CGCGCGGTGACCAGCATGGACGCCGCCGCCTACCACGACTACAAGCGCGTGGCGATGGAAGCGGTGCTGGCT 
TCCCATGGGCGGCTCGCCGCCGCCTACCGGGTGGTGATGGTGGAGGGCGCCGGCTCGCCGGCGGAGATCAAC 
CTGCGCGCCAACGACATCGCCAACATGGGCTTCGCCGAAGCGGTGGATTGCCCGGTGATCCTGGTCGCCGAT 
ATCGACCGCGGCGGGGTCTTCGCCCACCTGGTCGGCACCCTGGAACTGCTCTCCGACTCGGAGCGGGAGCGG 
GTCAAGGGCTTCGTCATCAATCGCTTCCGCGGCGACATCGCCCTGCTGCAACCCGGCCTCGACTGGCTGGAG 
GCGCGCACCGGCAAGCCGGTGCTCGGCGTGCTGCCCTATGTCAGCGACCTGCACCTGGAGGCGGAGGACGCC 
ATCGACACGCGCCAGGCGGCCAAGGTCGGGCCGCGCCTGAAGGTGGTGGTGCCGGTGCTGCCGAGGATCAGC 
AACCACACCGATTTCGATCCGCTGCGCCTGCACCCCCAGGTCGAGTTGAGCTTCGTCGGCCCCGGCCAGGCG 
CTGCCGTCGGCGGACCTGATCGTCCTGCCCGGCTCGAAGAGCGTGCGCGCCGACCTCGCGGCGCTGCGCGAG 
CGTGGCTGGGACGAGGCGATCCTCCGTCACCTGCGCTACGGCGGTCGCCTGCTGGGGATCTGCGGCGGCCTG 
CAGATGCTCGGCGAGCGCCTGCACGATCCGCTCGGCCTGGAAGGCGCGGCCGGCAGCAGCGCTGGCCTCGGC 
CTGCTGGCGTTGGAAACGACCCTGGAGGCGGACAAGCAATTGCGCAACGTACAGGGCCGCCTGAGCCTGGAG 
GACGCGCCGCTGTCGGGCTACGAGATCCATGCAGGGGTCACTCGTGGCGAGGCCCTGGCGCGGCCGGCGGTG 
GTGCTCGACGATGGCCGCGCGGATGGTGCCCGCAGCGTCGACGGGAACGTCATGGGCACCTACCTGCACGGC 
CTGTTCGAATCCACCGCGGCCTGTTCGGCGCTGCTGCGCTGGGCCGGCCTGCGCGAGGTCCAGGCGGTGGAC 
TACCAGGCCTTGCGCGAACGCGACATCGAGCGGCTCGCCGACCTGGTCGAGCGCAACCTGGATACCGGGCGA 
TTGCTCGCCCTCTGCGGAGAACCCCATGCGTGA