ViewGene
Locus Name:
GeneID:
Location:

GeneID:816
TrivialName: PA14_61250
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_61250
PAO1 Ortholog Locus:PA4628
Sequence Length:1464
Protein Length:487
Start: 5467349
Stop: 5468812
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08016.1|AE004877_3 (AE004877) lysine-specific permease [Pseudomonas aeruginosa PAO1]
Identities = 487/487 (100%), Positives = 487/487 (100%)
Sequence:
ATGACTGACCTGAACACCAGCCAGGGCCAGCAACTGCGGCGGGTGCTCAAGCCGCGCCACCTGAACATGATC
GCCATCGGCGGCTCCATCGGCACCGGGCTGTTCGTCGCCTCCGGGGCCACCGTGGCCACCGCCGGGCCCGGC
GGTGCGCTGCTTTCCTACGCCCTGATCGGGCTGATGGTGTACTTCCTCATGACCAGTCTCGGCGAGATGGCC
GCCTACATGCCCGTTTCCGGCTCGTTCTGCACCTATGGCAGCCGGTTCGTCGAAGATGGCTTCGGTTTCGCC
CTCGGCTGGAACTACTGGTACAACTGGGCGGTGACCATTGCCGCGGAACTGGTGGCGGCGCAACTGGTGATG
AGTTTCTGGTTCCCCGAGGTGCCGGGCATCTACTGGAGCGCGATCTTCCTGGGCATCATGTTCGGCCTCAAC
GTGATTTCCGCGCGTGGCTTCGGCGAGAGCGAATTCTGGTTCGCCCTGATCAAGGTAGTCACGGTGGTGATC
TTCATCGGCGTCGGCCTGGCGACCATCTTCGGCATCATGCATGGCGTGGAGTCGCCCGGCTTCAGCAACTTC
ACCATGGGCGACGCGCCCTTCGTCGGCGGCTTCCAGGCAATGGTCGGGGTGGCGATGATCGCCGGCTTCTCG
TTCCAGGGCACCGAGTTGATCGGCATCGCCGCCGGTGAATCGGAAAATCCGCGGAAGAACATCCCGATCGCC
ATTCGCCAGGTGTTCTGGCGCATCCTGATGTTCTACATCCTGGCGATCTTCGTGATCGGCATGCTGATTCCC
TACACCGACCCGAACCTGCTGAAGAACGATGCCAGCGACATCAGCGTGTCGCCCTTCACCCTGCTCTTCGAG
CGCGCCGGCTTCGCCGCGGCGGCCGGAGTGATGAACGCGGTGATCCTCTCGGCGATCCTCTCCGCCGGCAAC
TCCGGCATGTACGCCTCGACCCGGATGCTCTACAACCTCGCCCTCGAGGGCAAGGCACCGCGCCTGTTCTCC
CGTGTCTCGCGCAGCGGCGTGCCACGCAATGCGCTGTACGCCACTACCCTGGTCGGCGCCCTGTGCTTCCTC
ACTTCGGCCTTCGGCGACAGCACCGTCTACACATGGCTGCTGAACACCTCGGGCATGTGCGGCTTCATCGCC
TGGCTGGGCATCGCCATCTCCCACTATCGCTTCCGCAAGGGCTACCTGGCCCAGGGCGGCCGCCTGGAAGAC
CTGCCCTACCGGGCCAAGCTGTTCCCCTTCGGCCCGCTGTTCGCCTTCGCCCTGTGCATGGTCATCACCCTC
GGGCAGAACTACCAGGCGCTGGTGGGCGAACGCATCGACTGGATCGGCCTCCTCGCCACCTACATCAGCCTG
CCGCTGTTCCTGGCGATCTGGCTGGGATACCGCTGGAAGAAGCGCGCGCGCTTCGTTCGCTACCACGAAATG
GACGTCAGCCCGACCAATACCTGA
Translation:
MTDLNTSQGQQLRRVLKPRHLNMIAIGGSIGTGLFVASGATVATAGPGGALLSYALIGLMVYFLMTSLGEMA
AYMPVSGSFCTYGSRFVEDGFGFALGWNYWYNWAVTIAAELVAAQLVMSFWFPEVPGIYWSAIFLGIMFGLN
VISARGFGESEFWFALIKVVTVVIFIGVGLATIFGIMHGVESPGFSNFTMGDAPFVGGFQAMVGVAMIAGFS
FQGTELIGIAAGESENPRKNIPIAIRQVFWRILMFYILAIFVIGMLIPYTDPNLLKNDASDISVSPFTLLFE
RAGFAAAAGVMNAVILSAILSAGNSGMYASTRMLYNLALEGKAPRLFSRVSRSGVPRNALYATTLVGALCFL
TSAFGDSTVYTWLLNTSGMCGFIAWLGIAISHYRFRKGYLAQGGRLEDLPYRAKLFPFGPLFAFALCMVITL
GQNYQALVGERIDWIGLLATYISLPLFLAIWLGYRWKKRARFVRYHEMDVSPTNT*
AnnotationID:825GeneID:816
AnnotatorUID: diggins
Modification Date/Time: 2005-05-06 13:01:04
Gene Name:lysP
Confidence Code:2
GeneProduct:APC family lysine-specific permease
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(27) Transport of small molecules
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0833,COG1113,KOG1286
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAC90139.1| (AJ414147) putative lysine-specific permease [Yersinia pestis CO92]
          Length = 503

 Score =  726 bits (1873), Expect = 0.0
 Identities = 349/481 (72%), Positives = 411/481 (85%), Gaps = 1/481 (0%)

>gb|AAL21104.1| (AE008798) APC family lysine-specific permease [Salmonella
           typhimurium LT2]
          Length = 489

 Score =  724 bits (1869), Expect = 0.0
 Identities = 345/475 (72%), Positives = 400/475 (84%)








 
Structural Features:
COG0833, LysP, Amino acid transporters 
[Amino acid transport and metabolism]
CD-Length = 541 residues,  88.9% aligned
Score =  627 bits (1619), Expect = 2e-180
Identities = 260/482 (53%), Positives = 344/482 (71%), Gaps = 3/482 (0%)

COG1113, AnsP, Gamma-aminobutyrate permease and related permeases 
[Amino acid transport and metabolism]
CD-Length = 462 residues,  98.5% aligned
Score =  357 bits (919), Expect = 3e-99
Identities = 181/473 (38%), Positives = 268/473 (56%), Gaps = 20/473 (4%)

KOG1286, Amino acid transporters 
[Amino acid transport and metabolism]
CD-Length = 554 residues,  86.6% aligned
Score =  353 bits (906), Expect = 8e-98
Identities = 181/483 (37%), Positives = 256/483 (53%), Gaps = 17/483 (3%)






   
Genomic Context:






   
Comment:


















    ReferenceID:1635




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:18777




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31593




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:816_cdd.html


    		




 
URL:

















    ReferenceID:33327




  
Author/Investigator(s):
        Steffes C, Ellis J, Wu J, Rosen BP.





  
Title:
        The lysP gene encodes the lysine-specific permease.




  
PubMed:
        1315732


MedLine:
        




    
Source:
J Bacteriol. 1992 May;174(10):3242-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1315732

















    ReferenceID:33328




  
Author/Investigator(s):
        Popkin PS, Maas WK.





  
Title:
        Escherichia coli regulatory mutation affecting lysine transport and lysine decarboxylase.




  
PubMed:
        6767681


MedLine:
        




    
Source:
J Bacteriol. 1980 Feb;141(2):485-92.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6767681









           
Homologs By Global Alignment 

           

       



     
Gene ID:816
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
1467
                           PA4628_tr
                           translation of PA4628
                           487
                           99.99
                           99.99
                           0
                           2525.0
     

     
     
53383
                           gb|AAG08016.1|AE004877_3
                           (AE004877) lysine-specific permease [Pseudomonas aeruginosa PAO1]
                           487
                           99.99
                           99.99
                           0
                           2525.0
     

     
     
53388
                           emb|CAD02582.1|
                           (AL627273) lysine-specific permease [Salmonella enterica subsp. enterica serovar Typhi]
                           490
                           70.61
                           82.04
                           4
                           1859.0
     

     
     
53387
                           gb|AAO68356.1|
                           (AE016836) lysine-specific permease [Salmonella enterica subsp. enterica serovar Typhi Ty2]
                           490
                           70.61
                           82.04
                           4
                           1859.0
     

     
     
53386
                           gb|AAL21104.1|
                           (AE008798) APC family lysine-specific permease [Salmonella typhimurium LT2]
                           490
                           70.61
                           82.04
                           4
                           1859.0
     

     






      

          
GC ORFID: 43818How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4628Glimmer Score: 

          
Start: 4731029Stop: 4732492

          
Length: 1464


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4628 translation of PA4628Homolog Bit Score 977.0

          
Other Homologs:  t_PA4981 (ORF: BLASTX 375.0), t_PA4628 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACTGACCTGAACACCAGCCAGGGCCAGCAACTGCGGCGGGTGCTCAAGCCGCGCCACCTGAACATGATC 
GCCATCGGCGGCTCCATCGGCACCGGGCTGTTCGTCGCCTCCGGGGCCACCGTGGCCACCGCCGGGCCCGGC 
GGTGCGCTGCTTTCCTACGCCCTGATCGGGCTGATGGTGTACTTCCTCATGACCAGTCTCGGCGAGATGGCC 
GCCTACATGCCCGTTTCCGGCTCGTTCTGCACCTATGGCAGCCGGTTCGTCGAAGATGGCTTCGGTTTCGCC 
CTCGGCTGGAACTACTGGTACAACTGGGCGGTGACCATTGCCGCGGAACTGGTGGCGGCGCAACTGGTGATG 
AGTTTCTGGTTCCCCGAGGTGCCGGGCATCTACTGGAGCGCGATCTTCCTGGGCATCATGTTCGGCCTCAAC 
GTGATTTCCGCGCGTGGCTTCGGCGAGAGCGAATTCTGGTTCGCCCTGATCAAGGTAGTCACGGTGGTGATC 
TTCATCGGCGTCGGCCTGGCGACCATCTTCGGCATCATGCATGGCGTGGAGTCGCCCGGCTTCAGCAACTTC 
ACCATGGGCGACGCGCCCTTCGTCGGCGGCTTCCAGGCAATGGTCGGGGTGGCGATGATCGCCGGCTTCTCG 
TTCCAGGGCACCGAGTTGATCGGCATCGCCGCCGGTGAATCGGAAAATCCGCGGAAGAACATCCCGATCGCC 
ATTCGCCAGGTGTTCTGGCGCATCCTGATGTTCTACATCCTGGCGATCTTCGTGATCGGCATGCTGATTCCC 
TACACCGACCCGAACCTGCTGAAGAACGATGCCAGCGACATCAGCGTGTCGCCCTTCACCCTGCTCTTCGAG 
CGCGCCGGCTTCGCCGCGGCGGCCGGAGTGATGAACGCGGTGATCCTCTCGGCGATCCTCTCCGCCGGCAAC 
TCCGGCATGTACGCCTCGACCCGGATGCTCTACAACCTCGCCCTCGAGGGCAAGGCACCGCGCCTGTTCTCC 
CGTGTCTCGCGCAGCGGCGTGCCACGCAATGCGCTGTACGCCACTACCCTGGTCGGCGCCCTGTGCTTCCTC 
ACTTCGGCCTTCGGCGACAGCACCGTCTACACATGGCTGCTGAACACCTCGGGCATGTGCGGCTTCATCGCC 
TGGCTGGGCATCGCCATCTCCCACTATCGCTTCCGCAAGGGCTACCTGGCCCAGGGCGGCCGCCTGGAAGAC 
CTGCCCTACCGGGCCAAGCTGTTCCCCTTCGGCCCGCTGTTCGCCTTCGCCCTGTGCATGGTCATCACCCTC 
GGGCAGAACTACCAGGCGCTGGTGGGCGAACGCATCGACTGGATCGGCCTCCTCGCCACCTACATCAGCCTG 
CCGCTGTTCCTGGCGATCTGGCTGGGATACCGCTGGAAGAAGCGCGCGCGCTTCGTTCGCTACCACGAAATG 
GACGTCAGCCCGACCAATACCTGA