ViewGene
Locus Name:
GeneID:
Location:

GeneID:7371
TrivialName: PA14_41563
AnnotatorUID: danlee
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_41563
PAO1 Ortholog Locus:PA1778
Sequence Length:738
Protein Length:245
Start: 3711641
Stop: 3712378
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: PA1778 [gene=cobA] [prot=uroporphyrin-III C-methyltransferase], Length = 245, Score = 483 bits (1242), Expect = e-137, Identities = 244/245 (99%), Positives = 245/245 (99%). Replaces GeneID5787 (PA14_41565).
Sequence:
atgagcggtaaggtctggctggtgggtgcgggtcccggcgatccggaactgttgaccctgaaggcagttcgc
gccctgcaggacgcggatgtggtgatggtcgacgatttggtcaacccgagcatactggagcactgtccgtcc
gcccgggtggtccgggtcggcaaacgcggcggctgccgctccacaccgcaggacttcatccagcgcctgatg
ctgcggcatgcccgccagggacgcagcgtggtgcgcctgaaaggcggcgatccatgcatcttcggccgcgcc
ggcgaagaagccgaatggctggcccggcacgggatagacagcgagatagtgaacggcatcaccgccgggctg
gctggcgccactgcctgcggcataccgctgacctaccgcggcatcagccgcggcgtgaccctggtgaccgcg
catacccaggacgacagcccgctggcctgggaagccctggcacgcagcggtaccacgctggtggtctacatg
ggcgtcgcccgactcgcggagatccaggccgggctgctggctggaggcatggccgaggatacgccgctggcg
atgatcgagaacgccaccttgggcaaccagcgcgaatgccgcagcaacctcggcgagctactgcgggacgcc
ggacgtttcgccttgaaaagcccggcgatcctggtgatcggcgaagtaacccgcgacatcgtgtcgcaaccg
atttccctgagcgcctga
Translation:
MSGKVWLVGAGPGDPELLTLKAVRALQDADVVMVDDLVNPSILEHCPSARVVRVGKRGGCRSTPQDFIQRLM
LRHARQGRSVVRLKGGDPCIFGRAGEEAEWLARHGIDSEIVNGITAGLAGATACGIPLTYRGISRGVTLVTA
HTQDDSPLAWEALARSGTTLVVYMGVARLAEIQAGLLAGGMAEDTPLAMIENATLGNQRECRSNLGELLRDA
GRFALKSPAILVIGEVTRDIVSQPISLSA*
AnnotationID:7284GeneID:7371
AnnotatorUID: danlee
Modification Date/Time: 2005-12-02 15:03:28
Gene Name:cobA
Confidence Code:2
GeneProduct:uroporphyrin-III C-methyltransferase
Cell Localization:()
Synonyms:PA1778
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:S-adenosyl-L-methionine:uroporphyrinogen III
Functional Category Confidence Code:5
COGs:COG0007, pfam00590, COG2875
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
gi|9947758|gb|AAG05167.1|  uroporphyrin-III C-methyltransferase [Pseudomonas aeruginosa PAO1]
gi|15596975|ref|NP_250469.1|  uroporphyrin-III C-methyltransferase [Pseudomonas aeruginosa PAO1]
          Length=245

 Score =  461 bits (1185),  Expect = 1e-128
 Identities = 244/245 (99%), Positives = 245/245 (100%), Gaps = 0/245 (0%)

gi|67153429|ref|ZP_00415174.1|  Uroporphyrin-III C-methyltransferase, C-terminal [Azotobacter vinelandii AvOP]
gi|67087562|gb|EAM07028.1|  Uroporphyrin-III C-methyltransferase, C-terminal [Azotobacter vinelandii AvOP]
          Length=245

 Score =  354 bits (909),  Expect = 1e-96
 Identities = 185/245 (75%), Positives = 212/245 (86%), Gaps = 0/245 (0%)

gi|26988815|ref|NP_744240.1|  uroporphyrin-III C-methyltransferase [Pseudomonas putida KT2440]
gi|24983616|gb|AAN67704.1|  uroporphyrin-III C-methyltransferase [Pseudomonas putida KT2440]
          Length=246

 Score =  344 bits (883),  Expect = 1e-93
 Identities = 180/232 (77%), Positives = 200/232 (86%), Gaps = 0/232 (0%)

gi|82737947|ref|ZP_00900789.1|  Uroporphyrin-III C-methyltransferase, C-terminal [Pseudomonas putida F1]
gi|82714952|gb|EAP50024.1|  Uroporphyrin-III C-methyltransferase, C-terminal [Pseudomonas putida F1]
          Length=246

 Score =  344 bits (883),  Expect = 1e-93
 Identities = 181/232 (78%), Positives = 200/232 (86%), Gaps = 0/232 (0%)






 
Structural Features:
COG0007, CysG, Uroporphyrinogen-III methylase [Coenzyme metabolism].
             CD-Length = 244 residues,  95.9% aligned
             Score =  270 bits (693), Expect = 9e-74

pfam00590, TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases.
             CD-Length = 208 residues,  99.5% aligned
             Score =  190 bits (485), Expect = 9e-50

COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].
             CD-Length = 254 residues,  90.6% aligned
             Score =  155 bits (393), Expect = 6e-39






   
Genomic Context:






   
Comment: