ViewGene
Locus Name:
GeneID:
Location:

GeneID:7237
TrivialName: PA14_23370
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23370
PAO1 Ortholog Locus:
Sequence Length:1137
Protein Length:378
Start: 2028084
Stop: 2029220
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Sequence:
ATGCGAAAGAAGACTCTTTGTGTGTTTGGTACGCGGCCGGAGGCTATCAAAATGGCCCCGGTAACCCTGGCA
TTGGCGGACGATGATCGTTTCGAGGCGAGGGTATGCGTTACCGGCCAGCATCGTGAGATGCTTGACCAAGTC
TTGAATCTCTTCAAGATCGTCCCTGACTTCGATCTCAATATCATGCGTTCGGGGCAGGATCTGACTGATGTA
ACTGTTGCCATTCTGCAAGGAATGAAAGACGTTTTCTCTCAGTTCAAGCCCGATATCGTTCTTGTCCATGGC
GATACAGCCACGACGTTGGCTGCTAGCCTTGCTGCTTATTATCATCAGATCCCGGTTGCCCATGTCGAGGCG
GGATTGCGGACAGGGAACATGTATTCTCCGTGGCCTGAAGAGGGCAATCGGAAATTAACTGGTGCCTTAGCC
TGTCTTCACTTTGCTCCAACGGAGACTTCTAGGGACAACTTGCTTAGGGAAGGGATATCCGCCGAGCGAATT
CGTGTGACCGGAAATACTGTTATCGATGCCTTGTTAAATGTTGTGCAACGCTTGGAGCAAGATATGGAGCTT
GCCAGCGAGGCGGCGGCTCCGACTGAGTTTCTTGACTCCTCACGCAGGTTCATTCTTGTCACTGGCCATCGC
CGTGAAAGCTTTGGCGGAGGTTTCGAACGCATCTGTCAAGCACTGGGCGTGGTTGCAAGGAATCACCCAGAG
ATCGATATTGTTTATCCCGTTCATCTGAATCCGAATGTACGAGAGCCGGTCAATCGTCTACTTTCAGATGTT
CAGAACATTCATCTTATAGAGCCGTTGGACTATCTCCCTTTCGTTCATTTGATGAGCCGTGCTCATGTTATT
CTCACCGATTCCGGTGGTATTCAGGAGGAAGCGCCTTCGTTAGGTAAGCCCGTTTTGGTCATGCGGGAGACG
ACGGAGCGCCCGGAGGCTGTTGCCGCAGGAACCGTCAAGTTGGTCGGGACAGAAATCAAGAATATAGTTAAT
GAGCTTGAGCGTTTACTGGTAGATGAATCTGCCTATCGAAAAATGAGTTTTGCCCATAACCCTTACGGTGAT
GGAATGGCGAGTAAGCGAATCATTGACAGCCTCTTGGATGCGAAGAGAGGCGAGTAA
Translation:
MRKKTLCVFGTRPEAIKMAPVTLALADDDRFEARVCVTGQHREMLDQVLNLFKIVPDFDLNIMRSGQDLTDV
TVAILQGMKDVFSQFKPDIVLVHGDTATTLAASLAAYYHQIPVAHVEAGLRTGNMYSPWPEEGNRKLTGALA
CLHFAPTETSRDNLLREGISAERIRVTGNTVIDALLNVVQRLEQDMELASEAAAPTEFLDSSRRFILVTGHR
RESFGGGFERICQALGVVARNHPEIDIVYPVHLNPNVREPVNRLLSDVQNIHLIEPLDYLPFVHLMSRAHVI
LTDSGGIQEEAPSLGKPVLVMRETTERPEAVAAGTVKLVGTEIKNIVNELERLLVDESAYRKMSFAHNPYGD
GMASKRIIDSLLDAKRGE*
AnnotationID:7245GeneID:7237
AnnotatorUID: danlee
Modification Date/Time: 2005-10-14 12:12:46
Gene Name:ORF_5
Confidence Code:3
GeneProduct:similar to UDP-N-acetylglucosamine 2-epimerase
Cell Localization:()
Synonyms:orfK
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(7) Cell wall / LPS / capsule
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0381, pfam02350
Secondary Functional Category(ies):ptative enzyme
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
gi|20559945|gb|AAM27708.1|  ORF_5; similar to UDP-N-acetylglucosamine 2-epimerase [Pseudomonas aeruginosa]
gi|20559778|gb|AAM27557.1|  ORF_5; similar to UDP-N-acetylglucosamine 2-epimerase [Pseudomonas aeruginosa]
     Length=361
     Score =  712 bits (1839),  Expect = 0.0
     Identities = 361/361 (100%), Positives = 361/361 (100%), Gaps = 0/361 (0%)






 
Structural Features:
COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].
             CD-Length = 383 residues,  95.6% aligned
             Score =  464 bits (1195), Expect = 8e-132

pfam02350, Epimerase_2, UDP-N-acetylglucosamine 2-epimerase.
             CD-Length = 344 residues,  99.7% aligned
             Score =  367 bits (944), Expect = 1e-102






   
Genomic Context:
Part of variable O-antigen biosynthetic locus in P. aeruginosa.







   
Comment:
Most similar to the variant of ORF_5 found in P. aeruginosa serotypes 010 and 019.



















    ReferenceID:38216




  
Author/Investigator(s):
        Raymond,C.K., Sims,E.H., Kas,A., Spencer,D.H., Kutyavin,T.V., Ivey,R.G., Zhou,Y., Kaul,R., Clendenning,J.B. and Olson,M.V.





  
Title:
        Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa




  
PubMed:
        12057956


MedLine:
        




    
Source:
J. Bacteriol. 184 (13), 3614-3622 (2002)







    
Reference Type:Journal 







    
Data:


    		




 
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