ViewGene
Locus Name:
GeneID:
Location:

GeneID:7233
TrivialName: PA14_23450
AnnotatorUID: urbach
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23450
PAO1 Ortholog Locus:
Sequence Length:954
Protein Length:317
Start: 2039196
Stop: 2040149
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homolog: gb|AAM27716.1|AF498411_13 (AF498411) ORF_13; similar to NAD dependent epimerase/dehydratase family [Pseudomonas aeruginosa]
Sequence:
ATGAGAGTCTTTCTTACTGGTATAACGGGCTTTGTTGGGCTTGCTACTTCAAAGCGTCTACTGCAAGAGGGG
CATTGTGTGCGAGCGGCAGTGCGTGATGCCAATCCAGCGCTTGCGCAAGAAGTTGAGCAGGTTGTTTTTGGG
AATTTGGTAAAGCACGACTGGGCTTCTTCGCTTGAGGGGCAAGAGGTAGTGATACACTGTGCTGCTCGTGTT
CATGTGATGAAGGATGCATCCCGCGACCCTTTGAGTGAGTTTCGACGGGTCAATGTTGAGGGTACCCTAAAT
CTAGCGCGCCAGGCGGCGAAAGCTGGCGTCAAGAGGTTTGTTTTCATTAGCTCAATAAAGGTCAATGGTGAA
AGTACTAGACTGGGTGTTCCTTATACCGCTGATGATATTGCCATGCCGCTTGATCCATATGGCGTTTCCAAA
CTTGAGGCTGAACAGAAGCTGCTCTCTCTAGCCGCTCGGGTTGACATGGAAGTGAGCATAATACGGCCGGTT
TTGGTATATGGGCCAGGTGTAAAGGCGAATTTTTTGAGCATGATGGAATGGCTGAAAAAAGGAATGCCATTG
CCTCTTGGCGCTATTGATAATAAGCGTAGTCTGGTTGCGTTGGACAATCTGGTTGATCTTATTCTCACTTGT
ATGAAACATCCGGCTGCCGCAAATCAGATATTTCTCGTCAGCGACGATGAGGATCTTTCCACCACAGAATTA
TTGCGGCGTACCGGCAAAGCGATGGGGCGTCCAGCCAGGTTGATACCCATTCCATCTCGGTTTCTCGGTTTT
TCCGCTCGCTTGCTCGGTAAGCCGGCTATTGTGCAGCGTCTGTGCGAGTCGCTACAGGTCGATATTGAAAAG
ACTCGAGACCTGTTAGGCTGGCAGCCTCCTGTCAGCGTAGATGAAGCCTTGCATAAGACTGTGCATCACTTC
TTGGAGCATCAACAATAA
Translation:
MRVFLTGITGFVGLATSKRLLQEGHCVRAAVRDANPALAQEVEQVVFGNLVKHDWASSLEGQEVVIHCAARV
HVMKDASRDPLSEFRRVNVEGTLNLARQAAKAGVKRFVFISSIKVNGESTRLGVPYTADDIAMPLDPYGVSK
LEAEQKLLSLAARVDMEVSIIRPVLVYGPGVKANFLSMMEWLKKGMPLPLGAIDNKRSLVALDNLVDLILTC
MKHPAAANQIFLVSDDEDLSTTELLRRTGKAMGRPARLIPIPSRFLGFSARLLGKPAIVQRLCESLQVDIEK
TRDLLGWQPPVSVDEALHKTVHHFLEHQQ*
AnnotationID:7250GeneID:7233
AnnotatorUID: danlee
Modification Date/Time: 2005-10-14 13:01:44
Gene Name:ORF_13
Confidence Code:3
GeneProduct:similar to NAD dependent epimerase/dehydratase family
Cell Localization:()
Synonyms:orfM
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(7) Cell wall / LPS / capsule
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0451
Secondary Functional Category(ies):putative enzyme
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
gi|20559953|gb|AAM27716.1|  ORF_13; similar to NAD dependent epimerase/dehydratase family 
            [Pseudomonas aeruginosa]
 gi|20559786|gb|AAM27565.1|  ORF_13; similar to NAD dependent epimerase/dehydratase family 
            [Pseudomonas aeruginosa]
          Length=317

 Score =  623 bits (1606),  Expect = 3e-177
 Identities = 317/317 (100%), Positives = 317/317 (100%), Gaps = 0/317 (0%)






 
Structural Features:
COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer 
membrane / Carbohydrate transport and metabolism].
             CD-Length = 314 residues,  99.7% aligned
             Score =  174 bits (441), Expect = 1e-44

pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. 
             CD-Length = 310 residues, 100.0% aligned
             Score =  125 bits (316), Expect = 7e-30






   
Genomic Context:
Part of variable O-antigen biosynthetic locus in P. aeruginosa.







   
Comment:
Identical to ORF_13 found in P. aeruginosa serotypes 010 and 019.



















    ReferenceID:38221




  
Author/Investigator(s):
        Raymond,C.K., Sims,E.H., Kas,A., Spencer,D.H., Kutyavin,T.V., Ivey,R.G., Zhou,Y., Kaul,R., Clendenning,J.B. and Olson,M.V.





  
Title:
        Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa




  
PubMed:
        12057956


MedLine:
        




    
Source:
J. Bacteriol. 184 (13), 3614-3622 (2002)







    
Reference Type:Journal 







    
Data:


    		




 
URL: