ViewGene
Locus Name:
GeneID:
Location:

GeneID:70
TrivialName: PA14_45890
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_45890
PAO1 Ortholog Locus:PA1436
Sequence Length:3111
Protein Length:1036
Start: 4080262
Stop: 4077152
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04825.1|AE004573_4 (AE004573) probable RND efflux transporter [Pseudomonas aeruginosa PAO1]
Identities = 1035/1036 (99%), Positives = 1035/1036 (99%)
Sequence:
GTGACGCCGCGCGCCGGGATTTCCGGCTGGTGCGTACGGCACCCGATCGCCACCGCGCTGCTGACCCTGGCC
TCGCTGCTGCTGGGGCTGCTGGCGTTCCTCCGGCTCGGCGTGGCGCCGTTGCCGGAGGCGGACTTCCCGACC
ATCCAGATCAACGCCTTGCTGCCCGGCGGTAGCCCGGAAACCATGGCCTCGTCGGTGGCCACCCCCTTGGAA
GTGCAGTTCAGCGCGATTCCCGGGATCACCGAGATGACCTCCAGCAGCGCCCTGGGCACTACCACCCTGACC
CTGCAGTTCAGCCTCGACAAGAGCATCGACGTCGCCGCCCAGGAAGTCCAGGCGGCGATCAACGCCGCGGCC
GGGCGGCTGCCGGTGGACATGCCGAACCTGCCGACCTGGCGCAAGGTCAACCCGGCGGACAGCCCGATCATG
ATCCTGCGGGTCAACTCGGAGATGATGCCGCTGATCGAACTCAGCGATTACGCCGAGACCATCCTCGCCCGC
CAGCTCAGCCAGGTGAACGGCGTGGGGCAGATCTTCGTGGTCGGCCAGCAGCGCCCGGCGATCCGCATCCAG
GCCCAGCCGGAGAAGCTCGCCGCCTACCAGCTGACCCTGGCCGACCTGCGCCAGTCGTTGCAGTCGGCCAGC
GTCAACCTGGCCAAGGGTGCGCTCTACGGCGAGGGGCGGGTGTCGACCCTCGCGGCCAACGACCAGTTGTTC
AACGCCAGCGACTATGACGACCTGGTGGTCGCCTACCGCCAGGGCGCGCCGGTGTTCCTCAAGGACGTGGCG
CGGATCGTCTCGGCGCCCGAGGACGACTACGTGCAGGCCTGGCCGAACGGGGTGCCCGGGGTGGCGCTGGTG
ATCCTGCGCCAGCCTGGGGCGAACATCGTCGATACCGCCGACGCGATCCAGGCCGCGCTGCCACGCCTGCGC
GAGATGCTCCCGGCGACCATCGAGGTAGACGTGCTCAACGACCGCACCCGGACCATCCGCTCGTCGTTGCAC
GAGGTCGAACTGACCCTGCTGCTGACCATTGGCCTGGTGGTGCTGGTGATGGGCCTGTTCCTCCGCCAGCTG
TCGGCGACCCTGATCGTCGCTACGGTGCTGGCGGTGTCCCTGAGCGCCAGCTTCGCGGCGATGTACGTGCTC
GGCTTCACCCTCAACAACCTGACCCTGGTGGCGCTGATCATCGCCGTCGGCTTCATCGTCGACGACGCCATC
GTGGTCGTGGAGAACATCCACCGACACCTGGAAGCGGGCGCCTCGAAGGTCGAGGCGGCGCTCAAGGGCGCG
GCGGAGATCGGCTTTACCGTGATTTCCATCAGCTTCTCGCTGATCGCCGCGTTCATTCCCCTGCTGTTCATG
GGCGGGATCGTCGGCCGGCTGTTCCGCGAATTCGCGGTCAGCGTGACGGTGGCGATCCTGATCTCGGTGGTC
GCTTCGCTGACCCTGGCGCCGATGCTGGCTTCGCGCTTCATGCCGGCATTGCGGCATGCCGAAGCGCCGAGA
AAGGGCTTCGCCGAATGGCTGACCGGCGGCTACGAACGCGGCCTGCGCTGGGCGCTCGGGCACCAGCGGCTG
ATGCTGGTCGGCTTCGCCTTTACCGTGCTGGTGGCGGTGGCCGGCTACGTCGGGATTCCCAAGGGTTTCTTC
CCCTTGCAGGACACCGCCTTCGTCTTCGGCACGAGCCAGGCTGCCGAGGATATCTCCTACGACGACATGGTC
GCCAAGCACCGGCAACTGGCCGAGATCATCGCCAGCGACCCGGCGGTGCAGAGCTACAACCATGCGGTGGGC
GTCACCGGCGGTAGCCAGAGCCTGGCCAACGGGCGTTTCTGGATCGTCCTCAAGGACCGTGGCGAGCGCGAT
GTCTCGGTCGGCGAGTTCATCGACCGGCTGCGCCCGCAACTGGCCAAGGTGCCGGGAATCATGCTCTACCTG
CGCGCGGCGCAGGACATCAACCTCAGTTCCGGACCCTCGCGGACCCAGTACCAGTACGCCCTGCGCAGCAGC
GACAGCACCCAGCTGGCGCTCTGGGCGCAACGCCTCACCGAGCGCCTGAAGCAGGTGCCGGGGCTGATGGAT
GTGTCCAACGACCTGCAGGTCGGCGCCAGCGTCACCGCGCTGGACATCGACCGGGTGGCCGCGGCGCGTTTC
GGCCTCAGCGCCGAGGATGTCAGCCAGACCCTCTACGACGCCTTCGGCCAGCGCCAGGTCGGCGAGTACCAG
ACCGAGGTCAACCAGTACAAGGTGGTCCTCGAACTCGATGCGCGCCAGCGCGGCCGCGCGGAAAGCCTGGAC
TGGTTCTACCTGCGCTCGCCGCTGAGCGGCGAGATGGTCCCGCTGTCGGCCATCGCCAAGGTCGCGGCGCCG
CGCTCCGGGCCGCTGCAGATCAACCACAACGGCATGTTCCCGGCGGTCAACCTGTCCTTCAACCTGGCTGCC
GGGGTGTCTCTCGGCGAGGCGGTGCAGGCGGTGCAGCGCGCCCAGGAGGAGATCGGCATGCCCTCGACCATT
ATCGGCGTGTTCCAGGGCGCGGCGCAGGCCTTCCAGAGTTCGCTGGCCTCGCAACCGCTGCTGATCCTCGCC
GCGCTGATTGCGGTGTACATCATCCTCGGCGTGCTCTACGAGAGTTTCGTGCATCCGCTGACGATCCTTTCG
ACCCTGCCCTCGGCGGGGATCGGCGCGGTGTTCCTGCTCTGGGCCTGGGGCCAGGACTTCTCGATCATGGCG
CTGATCGGCATCGTGCTGCTGATCGGTATCGTCAAGAAGAACGGCATCCTCATGGTCGACTTCGCCATCGTC
GCCCAGCGCGAGCAGGGCATGAGCGCGGAGCAGGCGATCTACCAGGCCTGCCTGACCCGTTTCCGGCCGATC
ATGATGACCACCCTGGCCGCGCTGCTGGGCGCGATACCCCTGATGATCGGCTTCGGCACCGGTTCCGAGCTG
CGCCAGCCTCTGGGCATCGCGGTGGTCGGCGGGCTGCTGGTGAGCCAGGTGCTGACCCTGTTCAGCACGCCG
GTGGTATACCTGGCCCTGGAGCGGCTGTTCCACCGGCGCGGGGCGACGACCTCGGACGGCGGAACCGCTGGG
GCGACGGCGACATGA
Translation:
MTPRAGISGWCVRHPIATALLTLASLLLGLLAFLRLGVAPLPEADFPTIQINALLPGGSPETMASSVATPLE
VQFSAIPGITEMTSSSALGTTTLTLQFSLDKSIDVAAQEVQAAINAAAGRLPVDMPNLPTWRKVNPADSPIM
ILRVNSEMMPLIELSDYAETILARQLSQVNGVGQIFVVGQQRPAIRIQAQPEKLAAYQLTLADLRQSLQSAS
VNLAKGALYGEGRVSTLAANDQLFNASDYDDLVVAYRQGAPVFLKDVARIVSAPEDDYVQAWPNGVPGVALV
ILRQPGANIVDTADAIQAALPRLREMLPATIEVDVLNDRTRTIRSSLHEVELTLLLTIGLVVLVMGLFLRQL
SATLIVATVLAVSLSASFAAMYVLGFTLNNLTLVALIIAVGFIVDDAIVVVENIHRHLEAGASKVEAALKGA
AEIGFTVISISFSLIAAFIPLLFMGGIVGRLFREFAVSVTVAILISVVASLTLAPMLASRFMPALRHAEAPR
KGFAEWLTGGYERGLRWALGHQRLMLVGFAFTVLVAVAGYVGIPKGFFPLQDTAFVFGTSQAAEDISYDDMV
AKHRQLAEIIASDPAVQSYNHAVGVTGGSQSLANGRFWIVLKDRGERDVSVGEFIDRLRPQLAKVPGIMLYL
RAAQDINLSSGPSRTQYQYALRSSDSTQLALWAQRLTERLKQVPGLMDVSNDLQVGASVTALDIDRVAAARF
GLSAEDVSQTLYDAFGQRQVGEYQTEVNQYKVVLELDARQRGRAESLDWFYLRSPLSGEMVPLSAIAKVAAP
RSGPLQINHNGMFPAVNLSFNLAAGVSLGEAVQAVQRAQEEIGMPSTIIGVFQGAAQAFQSSLASQPLLILA
ALIAVYIILGVLYESFVHPLTILSTLPSAGIGAVFLLWAWGQDFSIMALIGIVLLIGIVKKNGILMVDFAIV
AQREQGMSAEQAIYQACLTRFRPIMMTTLAALLGAIPLMIGFGTGSELRQPLGIAVVGGLLVSQVLTLFSTP
VVYLALERLFHRRGATTSDGGTAGATAT*
AnnotationID:80GeneID:70
AnnotatorUID: diggins
Modification Date/Time: 2005-05-27 07:07:12
Gene Name:
Confidence Code:3
GeneProduct:putative RND efflux transporter
Cell Localization:()
Synonyms:PA1436
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(3) Antibiotic resistance and susceptibility
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam00873,COG0841
Secondary Functional Category(ies):transport of small molecules
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO54832.1| (AE016860) AcrB/AcrD/AcrF family protein [Pseudomonas syringae pv.
            tomato str. DC3000]
          Length = 1034

 Score = 1460 bits (3779), Expect = 0.0
 Identities = 739/1021 (72%), Positives = 869/1021 (85%)

>dbj|BAC49167.1| (AP005949) AcrB/AcrD/AcrF family protein [Bradyrhizobium japonicum
            USDA 110]
          Length = 1048

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 531/1019 (52%), Positives = 734/1019 (72%), Gaps = 11/1019 (1%)

>dbj|BAA15929.1| (D90845) Acriflavin resistance protein D. [Escherichia coli]
          Length = 1040

 Score =  946 bits (2446), Expect = 0.0
 Identities = 504/1018 (49%), Positives = 693/1018 (68%), Gaps = 9/1018 (0%)








 
Structural Features:
pfam00873, ACR_tran, AcrB/AcrD/AcrF family.
CD-Length = 1017 residues,  99.9% aligned
Score =  814 bits (2104), Expect = 0.0
Identities = 360/1020 (35%), Positives = 560/1020 (54%), Gaps = 16/1020 (1%)

COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms]
CD-Length = 1009 residues, 100.0% aligned
Score =  908 bits (2348), Expect = 0.0
Identities = 390/1018 (38%), Positives = 573/1018 (56%), Gaps = 15/1018 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14045




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17285




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37417




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:70_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:70
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
141
                           PA1436_tr
                           translation of PA1436
                           1036
                           99.90
                           99.90
                           0
                           5100.0
     

     
     
13379
                           gb|AAG04825.1|AE004573_4
                           (AE004573) probable RND efflux transporter [Pseudomonas aeruginosa PAO1]
                           1036
                           99.80
                           99.90
                           0
                           5097.0
     

     
     
13380
                           gb|AAO54832.1|
                           (AE016860) AcrB/AcrD/AcrF family protein [Pseudomonas syringae pv. tomato str. DC3000]
                           1040
                           71.25
                           83.84
                           10
                           3770.0
     

     
     
13381
                           emb|CAE28924.1|
                           (BX572604) RND efflux transporter [Rhodopseudomonas palustris CGA009]
                           1057
                           52.22
                           70.29
                           33
                           2714.0
     

     
     
13384
                           emb|CAD18350.1|
                           (AL646083) PROBABLE DRUG EFFLUX TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]
                           1047
                           51.09
                           66.76
                           25
                           2535.0
     

     






      

          
GC ORFID: 43072How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1436Glimmer Score: 

          
Start: 873647Stop: 876757

          
Length: 3111


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1436 translation of PA1436Homolog Bit Score 1969.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4945 (ORF: BLASTX 1459.0), t_PA2527 (ORF: BLASTX 961.0), t_PA2526 (ORF: BLASTX 899.0), psyr_15may02_Scaffold1_revised_gene1404 (ORF: BLASTX 853.0), t_PA1436 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGACGCCGCGCGCCGGGATTTCCGGCTGGTGCGTACGGCACCCGATCGCCACCGCGCTGCTGACCCTGGCC 
TCGCTGCTGCTGGGGCTGCTGGCGTTCCTCCGGCTCGGCGTGGCGCCGTTGCCGGAGGCGGACTTCCCGACC 
ATCCAGATCAACGCCTTGCTGCCCGGCGGTAGCCCGGAAACCATGGCCTCGTCGGTGGCCACCCCCTTGGAA 
GTGCAGTTCAGCGCGATTCCCGGGATCACCGAGATGACCTCCAGCAGCGCCCTGGGCACTACCACCCTGACC 
CTGCAGTTCAGCCTCGACAAGAGCATCGACGTCGCCGCCCAGGAAGTCCAGGCGGCGATCAACGCCGCGGCC 
GGGCGGCTGCCGGTGGACATGCCGAACCTGCCGACCTGGCGCAAGGTCAACCCGGCGGACAGCCCGATCATG 
ATCCTGCGGGTCAACTCGGAGATGATGCCGCTGATCGAACTCAGCGATTACGCCGAGACCATCCTCGCCCGC 
CAGCTCAGCCAGGTGAACGGCGTGGGGCAGATCTTCGTGGTCGGCCAGCAGCGCCCGGCGATCCGCATCCAG 
GCCCAGCCGGAGAAGCTCGCCGCCTACCAGCTGACCCTGGCCGACCTGCGCCAGTCGTTGCAGTCGGCCAGC 
GTCAACCTGGCCAAGGGTGCGCTCTACGGCGAGGGGCGGGTGTCGACCCTCGCGGCCAACGACCAGTTGTTC 
AACGCCAGCGACTATGACGACCTGGTGGTCGCCTACCGCCAGGGCGCGCCGGTGTTCCTCAAGGACGTGGCG 
CGGATCGTCTCGGCGCCCGAGGACGACTACGTGCAGGCCTGGCCGAACGGGGTGCCCGGGGTGGCGCTGGTG 
ATCCTGCGCCAGCCTGGGGCGAACATCGTCGATACCGCCGACGCGATCCAGGCCGCGCTGCCACGCCTGCGC 
GAGATGCTCCCGGCGACCATCGAGGTAGACGTGCTCAACGACCGCACCCGGACCATCCGCTCGTCGTTGCAC 
GAGGTCGAACTGACCCTGCTGCTGACCATTGGCCTGGTGGTGCTGGTGATGGGCCTGTTCCTCCGCCAGCTG 
TCGGCGACCCTGATCGTCGCTACGGTGCTGGCGGTGTCCCTGAGCGCCAGCTTCGCGGCGATGTACGTGCTC 
GGCTTCACCCTCAACAACCTGACCCTGGTGGCGCTGATCATCGCCGTCGGCTTCATCGTCGACGACGCCATC 
GTGGTCGTGGAGAACATCCACCGACACCTGGAAGCGGGCGCCTCGAAGGTCGAGGCGGCGCTCAAGGGCGCG 
GCGGAGATCGGCTTTACCGTGATTTCCATCAGCTTCTCGCTGATCGCCGCGTTCATTCCCCTGCTGTTCATG 
GGCGGGATCGTCGGCCGGCTGTTCCGCGAATTCGCGGTCAGCGTGACGGTGGCGATCCTGATCTCGGTGGTC 
GCTTCGCTGACCCTGGCGCCGATGCTGGCTTCGCGCTTCATGCCGGCATTGCGGCATGCCGAAGCGCCGAGA 
AAGGGCTTCGCCGAATGGCTGACCGGCGGCTACGAACGCGGCCTGCGCTGGGCGCTCGGGCACCAGCGGCTG 
ATGCTGGTCGGCTTCGCCTTTACCGTGCTGGTGGCGGTGGCCGGCTACGTCGGGATTCCCAAGGGTTTCTTC 
CCCTTGCAGGACACCGCCTTCGTCTTCGGCACGAGCCAGGCTGCCGAGGATATCTCCTACGACGACATGGTC 
GCCAAGCACCGGCAACTGGCCGAGATCATCGCCAGCGACCCGGCGGTGCAGAGCTACAACCATGCGGTGGGC 
GTCACCGGCGGTAGCCAGAGCCTGGCCAACGGGCGTTTCTGGATCGTCCTCAAGGACCGTGGCGAGCGCGAT 
GTCTCGGTCGGCGAGTTCATCGACCGGCTGCGCCCGCAACTGGCCAAGGTGCCGGGAATCATGCTCTACCTG 
CGCGCGGCGCAGGACATCAACCTCAGTTCCGGACCCTCGCGGACCCAGTACCAGTACGCCCTGCGCAGCAGC 
GACAGCACCCAGCTGGCGCTCTGGGCGCAACGCCTCACCGAGCGCCTGAAGCAGGTGCCGGGGCTGATGGAT 
GTGTCCAACGACCTGCAGGTCGGCGCCAGCGTCACCGCGCTGGACATCGACCGGGTGGCCGCGGCGCGTTTC 
GGCCTCAGCGCCGAGGATGTCAGCCAGACCCTCTACGACGCCTTCGGCCAGCGCCAGGTCGGCGAGTACCAG 
ACCGAGGTCAACCAGTACAAGGTGGTCCTCGAACTCGATGCGCGCCAGCGCGGCCGCGCGGAAAGCCTGGAC 
TGGTTCTACCTGCGCTCGCCGCTGAGCGGCGAGATGGTCCCGCTGTCGGCCATCGCCAAGGTCGCGGCGCCG 
CGCTCCGGGCCGCTGCAGATCAACCACAACGGCATGTTCCCGGCGGTCAACCTGTCCTTCAACCTGGCTGCC 
GGGGTGTCTCTCGGCGAGGCGGTGCAGGCGGTGCAGCGCGCCCAGGAGGAGATCGGCATGCCCTCGACCATT 
ATCGGCGTGTTCCAGGGCGCGGCGCAGGCCTTCCAGAGTTCGCTGGCCTCGCAACCGCTGCTGATCCTCGCC 
GCGCTGATTGCGGTGTACATCATCCTCGGCGTGCTCTACGAGAGTTTCGTGCATCCGCTGACGATCCTTTCG 
ACCCTGCCCTCGGCGGGGATCGGCGCGGTGTTCCTGCTCTGGGCCTGGGGCCAGGACTTCTCGATCATGGCG 
CTGATCGGCATCGTGCTGCTGATCGGTATCGTCAAGAAGAACGGCATCCTCATGGTCGACTTCGCCATCGTC 
GCCCAGCGCGAGCAGGGCATGAGCGCGGAGCAGGCGATCTACCAGGCCTGCCTGACCCGTTTCCGGCCGATC 
ATGATGACCACCCTGGCCGCGCTGCTGGGCGCGATACCCCTGATGATCGGCTTCGGCACCGGTTCCGAGCTG 
CGCCAGCCTCTGGGCATCGCGGTGGTCGGCGGGCTGCTGGTGAGCCAGGTGCTGACCCTGTTCAGCACGCCG 
GTGGTATACCTGGCCCTGGAGCGGCTGTTCCACCGGCGCGGGGCGACGACCTCGGACGGCGGAACCGCTGGG 
GCGACGGCGACATGA