pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family)
contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the
C-terminal helix-turn-helix domain of resolvase - see pfam02796.
CD-Length = 139 residues, 99.3% aligned
Score = 124 bits (313), Expect = 6e-30
COG1961, PinR, Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair].
CD-Length = 222 residues, 88.3% aligned
Score = 89.8 bits (222), Expect = 2e-19
Genomic Context:
Comment:
Associated with transposons identified in strains resistant to mercury or multiple antibiotics, in some
cases producint metallo-beta-lactamases.
ReferenceID:16222
Author/Investigator(s):
GenNotator
Title:
PubMed:
MedLine:
Source:
Reference Type:
BLASTP
Data:
URL:
ReferenceID:16953
Author/Investigator(s):
Walsh,T.R., Toleman,M.A., Hryniewicz,W., Bennett,P.M. and
Jones,R.N.
Title:
Evolution of an integron carrying blaVIM-2 in Eastern Europe:
report from the SENTRY Antimicrobial Surveillance Program
Toleman,M.A., Biedenbach,D., Bennett,D., Jones,R.N. and Walsh,T.R.
Title:
Genetic characterization of a novel metallo-beta-lactamase gene, blaIMP-13, harboured by a novel Tn5051-type transposon disseminating carbapenemase genes in Europe: report from the SENTRY worldwide antimicrobial surveillance programme