ViewGene

Locus Name:
GeneID:
Location:

GeneID:6450
TrivialName: PA14_15450
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_15450
PAO1 Ortholog Locus:
Sequence Length:366
Protein Length:121
Start: 1308685
Stop: 1308320
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: emb|CAD97550.1| (AJ564903) coregulator protein [uncultured bacterium]
Identities = 121/121 (100%), Positives = 121/121 (100%)
Sequence:
ATGAACGCCTACACGGTGTCCCGGCTGGCTCTTGATGCCGGGGTGAGCGTGCATATCGTGCGCGACTACCTG
CTGCGCGGATTGCTGCGCCCGGTGGCGTGCACACCAGGCGGCTACGGCTTGTTCGATGACGCCGCCTTGCAA
CGGCTGTGCTTCGTGCGGGCGGCCTTCGAGGCGGGCATCGGCCTCGACGCGCTGGCGCGGCTGTGCCGGGCG
CTGGATGCGGCGGACGGCGACGAAGCGGCCGCGCAGCTTGCCCTGCTGCGTCAGTTCGTCGAGCGTCGGCGC
GAAGCGTTGGCCGATCTGGAAGTGCAGTTGGCCACCCTGCCGACCGAGCCGGCACAGCACGCGGAGAGTCTG
CCATGA
Translation:
MNAYTVSRLALDAGVSVHIVRDYLLRGLLRPVACTPGGYGLFDDAALQRLCFVRAAFEAGIGLDALARLCRA
LDAADGDEAAAQLALLRQFVERRREALADLEVQLATLPTEPAQHAESLP*
AnnotationID:6451GeneID:6450
AnnotatorUID: danlee
Modification Date/Time: 2005-10-17 16:04:10
Gene Name:merD
Confidence Code:2
GeneProduct:Mercuric resistence transcriptional repressor protein MerD
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:mercury resistance
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:cd01111
Secondary Functional Category(ies):Adaptation, protection
EC Number:
Status:ACTIVE
Pathway:
mercury resistance
Homology:
gi|68526339|gb|EAN49311.1|  regulatory protein, MerR [Ralstonia metallidurans CH34]
gi|56130732|ref|YP_145635.1|  putative secondary regulatory protein [Ralstonia metallidurans CH34]
gi|39777490|gb|AAR31065.1|  mercury coregulator protein [Wautersia eutropha]
gi|72384296|ref|YP_293649.1|  Mercuric resistence transcriptional repressor protein MerD [Ralstonia eutropha JMP134]
     Length=121
     Score =  237 bits (604),  Expect = 9e-62
     Identities = 121/121 (100%), Positives = 121/121 (100%), Gaps = 0/121 (0%)

gi|2944143|gb|AAC38221.1|  MerD [Pseudomonas stutzeri]
     Length=121
     Score =  235 bits (599),  Expect = 4e-61
     Identities = 120/121 (99%), Positives = 121/121 (100%), Gaps = 0/121 (0%)

gi|43719|emb|CAA77324.1|  merD protein [Pseudomonas aeruginosa]
gi|6706115|emb|CAB65955.1|  MerD protein [Acinetobacter lwoffii]
gi|6706109|emb|CAB65951.1|  MerD protein [Acinetobacter lwoffii]
gi|127003|sp|P06689|MERD_PSEAE  HTH-type transcriptional regulator merD (Mercuric resistance protein merD)
     Length=121
     Score =  234 bits (598),  Expect = 5e-61
     Identities = 120/121 (99%), Positives = 120/121 (99%), Gaps = 0/121 (0%)
Structural Features:
cd01111, HTH_MerD, Helix-turn-helix transcription regulator MerD. The putative secondary regulator of 
mercury resistance (mer) operons, MerD, has been shown to down regulate the expression of this operon in 
gram-negative bacteria. It binds to the same operator DNA as MerR that activates transcription of the operon 
in the presence of mercury ions. 
             CD-Length = 102 residues, 100.0% aligned
             Score =  112 bits (280), Expect = 2e-26
Genomic Context:
Comment:
ReferenceID:12709
Author/Investigator(s): GenNotator
Title:
PubMed:
MedLine:
Source:
Reference Type:BLASTP
Data:
URL:
ReferenceID:16951
Author/Investigator(s): Schneiker,S., Keller,M., Droge,M., Lanka,E., Puhler,A. and Selbitschka,W.
Title: The genetic organization and evolution of the broad host range mercury resistance plasmid pSB102 isolated from a microbial population residing in the rhizosphere of alfalfa
PubMed: 11812851
MedLine: 21671848
Source:
JOURNAL   Nucleic Acids Res. 29 (24), 5169-5181 (2001)
Reference Type:Journal
Data:
URL:
ReferenceID:30005
Author/Investigator(s): GenNotator
Title: CDD Search
PubMed:
MedLine:
Source:
Reference Type:RPSBLAST
Data:
URL:
Homologs By Global Alignment
Gene ID:6450

Identity:

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
HomologID Accession Description Length PctIdentity PctSimilarity Gaps Score
199478 emb|CAD97550.1| (AJ564903) coregulator protein [uncultured bacterium] 121 99.99 99.99 0 604.0
199479 gb|AAC38221.1| (U80214) MerD [Pseudomonas stutzeri] 121 99.17 99.99 0 599.0
199480 emb|CAA77324.1| (Z00027) merD protein [Pseudomonas aeruginosa] 121 99.17 99.17 0 598.0
199481 emb|CAB65955.1| (AJ251540) MerD protein [Acinetobacter lwoffii] 121 99.17 99.17 0 598.0
199482 emb|CAB65951.1| (AJ251538) MerD protein [Acinetobacter lwoffii] 121 99.17 99.17 0 598.0
GC ORFID: 49452How Found: Glimmer
GC_TrimmedSeqID: 69Blast Result ID
Subject Sequence Name: Glimmer Score:
Start: 3645252Stop: 3645617
Length: 366
Start Codon: ATGTruncated Start:
Stop Codon: TGATruncated Stop:
Homolog: Homolog Bit Score
Other Homologs:
GC ORF Sequence
ATGAACGCCTACACGGTGTCCCGGCTGGCTCTTGATGCCGGGGTGAGCGTGCATATCGTGCGCGACTACCTG
CTGCGCGGATTGCTGCGCCCGGTGGCGTGCACACCAGGCGGCTACGGCTTGTTCGATGACGCCGCCTTGCAA
CGGCTGTGCTTCGTGCGGGCGGCCTTCGAGGCGGGCATCGGCCTCGACGCGCTGGCGCGGCTGTGCCGGGCG
CTGGATGCGGCGGACGGCGACGAAGCGGCCGCGCAGCTTGCCCTGCTGCGTCAGTTCGTCGAGCGTCGGCGC
GAAGCGTTGGCCGATCTGGAAGTGCAGTTGGCCACCCTGCCGACCGAGCCGGCACAGCACGCGGAGAGTCTG
CCATGA