ViewGene

Locus Name:
GeneID:
Location:

GeneID:6447
TrivialName: PA14_15480
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_15480
PAO1 Ortholog Locus:
Sequence Length:435
Protein Length:144
Start: 1311170
Stop: 1311604
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: emb|CAA83898.1| (Z33490) regulatory protein [Pseudomonas fluorescens]
Identities = 144/144 (100%), Positives = 144/144 (100%)
Sequence:
ATGGAAAACAATTTGGAGAACCTGACCATTGGCGTTTTCGCCAAGGCGGCCGGGGTCAATGTGGAGACCATC
CGTTTCTATCAGCGCAAGGGCTTGTTGCTGGAGCCTGACAAGCCCTATGGCAGCATCCGCCGCTATGGCGAG
GCGGATGTAACGCGGGTGCGCTTCGTGAAATCAGCCCAGCGGCTGGGCTTCAGCCTGGATGAGATCGCCGAG
CTGCTGCGGCTGGAGGATGGCACCCATTGCGAGGAAGCCAGCAGTCTGGCCGAGCACAAGCTCAAGGACGTG
CGCGAGAAAATGGCTGACCTGGCGCGCATGGAGGCCGTGCTGTCTGAGTTGGTGTGCGCCTGCCATGCGCGA
AGGGGGAACGTTTCCTGCCCGCTGATCGCGTCACTACAGGGTGGAGCAAGCTTGGCAGGTTCGGCTATGCCT
TAG
Translation:
MENNLENLTIGVFAKAAGVNVETIRFYQRKGLLLEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAE
LLRLEDGTHCEEASSLAEHKLKDVREKMADLARMEAVLSELVCACHARRGNVSCPLIASLQGGASLAGSAMP
*
AnnotationID:6448GeneID:6447
AnnotatorUID: danlee
Modification Date/Time: 2005-10-17 17:05:41
Gene Name:merR
Confidence Code:2
GeneProduct:Regulatory protein merR
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:cd01108
Secondary Functional Category(ies):adaptation, protection
EC Number:
Status:ACTIVE
Pathway:
Homology:
gi|13310754|gb|AAK18578.1|  Tn501 repressor [Shigella flexneri]
     Length=172
     Score =  283 bits (725),  Expect = 9e-76
     Identities = 144/144 (100%), Positives = 144/144 (100%), Gaps = 0/144 (0%)

gi|68560157|ref|ZP_00599477.1|  regulatory protein, MerR [Ralstonia metallidurans CH34]
gi|607154|emb|CAA83898.1|  regulatory protein [Pseudomonas fluorescens]
gi|607168|emb|CAA83897.1|  regulatory protein [Pseudomonas sp.]
gi|43715|emb|CAA77320.1|  merR protein (repressor/inducer) [Pseudomonas aeruginosa]
gi|56068726|emb|CAI11288.1|  activator/repressor of mer operon [Ralstonia metallidurans CH34]
gi|60392654|sp|P0A183|MERR_PSEAE  Mercuric resistance operon regulatory protein
gi|2944139|gb|AAC38217.1|  MerR [Pseudomonas stutzeri]
gi|1084045|pir||S51755  regulatory protein merR - Pseudomonas sp
     Length=144
     Score =  283 bits (725),  Expect = 9e-76
     Identities = 144/144 (100%), Positives = 144/144 (100%), Gaps = 0/144 (0%)
Structural Features:
cd01108, HTH_CueR, Helix-turn-helix transcription regulator CueR. The CueR-like proteins have been 
shown to activate metal ion efflux and resistance regulons in many eubacterial species. 
             CD-Length = 126 residues, 100.0% aligned
             Score =  162 bits (411), Expect = 2e-41

cd00592, HTH_MERR, Helix-turn-helix transcription regulator MERR, N-terminal domain. The MERR family 
transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, 
drugs, or oxygen radicals in eubacterial and some archaeal species. 
             CD-Length = 99 residues, 100.0% aligned
             Score = 98.1 bits (244), Expect = 4e-22
Genomic Context:
Comment:
ReferenceID:12703
Author/Investigator(s): GenNotator
Title:
PubMed:
MedLine:
Source:
Reference Type:BLASTP
Data:
URL:
ReferenceID:16950
Author/Investigator(s): Misra,T.K., Brown,N.L., Fritzinger,D.C., Pridmore,R.D., Barnes,W.M., Haberstroh,L. and Silver,S
Title: Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory regi and the first two structural genes
PubMed: 6091128
MedLine: 85014891
Source:
JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 81 (19), 5975-5979 (1984)
Reference Type:Journal
Data:
URL:
ReferenceID:29999
Author/Investigator(s): GenNotator
Title: CDD Search
PubMed:
MedLine:
Source:
Reference Type:RPSBLAST
Data:
URL:
Homologs By Global Alignment
Gene ID:6447

Identity:

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
HomologID Accession Description Length PctIdentity PctSimilarity Gaps Score
199241 emb|CAD97554.1| (AJ564903) repressor protein [uncultured bacterium] 144 99.99 99.99 0 725.0
199242 emb|CAA83898.1| (Z33490) regulatory protein [Pseudomonas fluorescens] 144 99.99 99.99 0 725.0
199243 emb|CAA83897.1| (Z33489) regulatory protein [Pseudomonas sp.] 144 99.99 99.99 0 725.0
199244 emb|CAA77320.1| (Z00027) merR protein (repressor/inducer) [Pseudomonas aeruginosa] 144 99.99 99.99 0 725.0
199246 gb|AAC38217.1| (U80214) MerR [Pseudomonas stutzeri] 144 99.99 99.99 0 725.0
GC ORFID: 49449How Found: Glimmer
GC_TrimmedSeqID: 69Blast Result ID
Subject Sequence Name: Glimmer Score:
Start: 3642767Stop: 3642333
Length: 435
Start Codon: ATGTruncated Start:
Stop Codon: TAGTruncated Stop:
Homolog: Homolog Bit Score
Other Homologs:
GC ORF Sequence
ATGGAAAACAATTTGGAGAACCTGACCATTGGCGTTTTCGCCAAGGCGGCCGGGGTCAATGTGGAGACCATC
CGTTTCTATCAGCGCAAGGGCTTGTTGCTGGAGCCTGACAAGCCCTATGGCAGCATCCGCCGCTATGGCGAG
GCGGATGTAACGCGGGTGCGCTTCGTGAAATCAGCCCAGCGGCTGGGCTTCAGCCTGGATGAGATCGCCGAG
CTGCTGCGGCTGGAGGATGGCACCCATTGCGAGGAAGCCAGCAGTCTGGCCGAGCACAAGCTCAAGGACGTG
CGCGAGAAAATGGCTGACCTGGCGCGCATGGAGGCCGTGCTGTCTGAGTTGGTGTGCGCCTGCCATGCGCGA
AGGGGGAACGTTTCCTGCCCGCTGATCGCGTCACTACAGGGTGGAGCAAGCTTGGCAGGTTCGGCTATGCCT
TAG