ViewGene
Locus Name:
GeneID:
Location:

GeneID:64
TrivialName: PA14_31900
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_31900
PAO1 Ortholog Locus:PA2526
Sequence Length:3111
Protein Length:1036
Start: 2776460
Stop: 2779570
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05914.1|AE004680_2 (AE004680) probable RND efflux transporter [Pseudomonas aeruginosa PAO1]
Identities = 1036/1036 (100%), Positives = 1036/1036 (100%)
Sequence:
ATGAGCCTGTCCACGCCCTTCATCCGCCGCCCGGTCGCCACCACGCTGCTGACCCTGGCGTTGCTGCTGGCC
GGCACCCTGTCGTTCGGTCTGCTGCCGGTGGCGCCGCTGCCCAACGTCGATTTTCCGGCCATCGTGGTCAGC
GCCAGCCTGCCGGGCGCCAGCCCGGAAACCATGGCCTCGTCGGTGGCCACGCCGCTGGAGCGCTCGCTGGGA
CGGATCGCCGGGATCAGCGAGATGACCTCCAGCAGTTCGCTGGGCTCGACCACCGTGGTGCTCGTGTTCGAC
CTGGAGAAGGACATCGACGGCGCCGCCCGCGAGGTGCAGGCGGCGATCAACGGCGCGATGAGCCTGCTGCCC
AGCGGCATGCCGAACAATCCCAGCTACCGCAAGGCCAACCCCTCGGACATGCCGATCATGGTCCTCACCCTG
ACCTCGGAGACCCAGAGTCGCGGCGAGATGTACGACCTCGCCTCGACCGTGCTGGCGCCGAAGCTGTCGCAG
GTGCAGGGGGTAGGGCAGGTGAGCATCGGCGGCAGCTCGCTGCCGGCGGTGCGGGTCGACCTCAACCCGGAT
GCCATGAGCCAGTACGGGCTGTCCCTGGACAGCGTGCGCACGGCCATCGCCGCGGCCAACAGCAACGGCCCC
AAGGGCGCCGTCGAGAAGGACGACAAGCACTGGCAGGTGGACGCCAACGACCAGTTGCGCAAGGCCCGCGAG
TACGAGCCGCTGGTGATCCACTACAACGCCGACAACGGCGCCGCGGTGCGCCTCGGCGACGTGGCCAAGGTC
AGCGACTCGGTGGAGGACGTGCGCAACGCCGGCTTCTCCGACGACCTGCCGGCGGTGCTGCTGATCGTCACC
CGCCAGCCCGGCGCCAACATCATCGAGGCCACCGACGCCATCCACGCGCAACTGCCGGTGTTGCAGGAACTG
CTCGGGCCGCAGGTCAAGCTGAACGTGATGGATGATCGCAGCCCGTCGATCCGCGCGTCGCTGGAAGAGGCC
GAGCTGACCCTGCTGATCTCGGTGGCGCTGGTGATCCTGGTGGTCTTCCTGTTCCTGCGCAACGGCCGCGCC
ACGCTGATCCCCAGCCTGGCGGTGCCGGTCTCGCTGATCGGCACCTTCGCGGTCATGTACCTGTGCGACTTC
AGCCTGAACAACCTGTCGCTGATGGCGCTGATCATCGCCACCGGCTTCGTGGTGGACGACGCCATTGTGGTG
GTGGAAAACATCGCCCGACGCATCGAGGAGGGCGATCCGCCGATCCAGGCGGCGATCACCGGCGCCCGCCAG
GTCGGTTTCACCGTGTTGTCGATGACGCTCTCGCTGGTCGCGGTGTTCATCCCGCTGCTGCTCATGGGCGGC
CTCACCGGGCGGTTGTTCCGCGAGTTCGCGGTGACTCTCTCGGCGGCGATCCTGGTGTCCCTGGTGGTATCC
CTGACCCTCACGCCGATGCTCTGCGCGCGTCTGCTGCGTCCGCTGAAACGGCCCGAGGGCGCCTCCCTGGCG
CGGCGCAGCGATCGCTTCTTCGCCGCCTTCATGCTGCGCTACCGCGCCAGCCTGGGCTGGGCGCTGGAGCAC
TCGCGGCTGATGGTGGTGATCATGCTGGCCTGCATCGCCATGAACCTCTGGTTGTTCGTGGTGGTGCCCAAG
GGCTTCCTCCCGCAGCAGGACTCCGGGCGCCTGCGCGGCTACGCGGTgGCCGACCAGAGCATCTCGTTCCAG
TCCCTGAGCGCGAAGATGGGCGAGTACCGCAAGATCCTCTCTTCCGATCCGGCGGTGGAAAACGTGGTCGGC
TTCATCGGCGGCGGCCGCTGGCAGTCGAGCAACACCGGTTCGTTCTTCGTCACCCTCAAGCCGATCGGCGAA
CGCGACCCGGTGGAGAAGGTCCTCACCCGGCTGCGCGAGCGGATCGCCAAGGTGCCCGGCGCGGCGCTCTAT
CTCAATGCCGGCCAGGACGTGCGCCTGGGCGGCCGCGACAGCAACGCGCAGTACGAATTCACCCTGCGCAGC
GACGACCTGACCCTGCTCCGCGAATGGGCGCCGAAGGTCGAGGCGGCGATGCGCAAGCTGCCGCAGCTGGTG
GACGTCAACAGCGACTCCCAGGACAAGGGCGTGCAGACCCGCCTGGTGATCGACCGCGACCGTGCGGCGACC
CTGGGGATCAACGTGGAAATGGTCGACGCGGTGCTCAACGATTCCTTCGGCCAGCGCCAGGTGTCGACCATC
TTCAACCCGCTGAACCAGTACCGGGTGGTGATGGAGGTCGACCAGCAGTACCAGCAGAGCCCGGAGATCCTC
CGCCAGGTCCAGGTGATCGGCAACGACGGCCAGCGCGTGCCGCTGTCCGCGTTCAGCCACTACGAACCGAGC
CGGGCACCGCTGGAAGTCAACCACCAGGGCCAGTTCGCCGCCACCACGCTGTCCTTCAACCTGGCGCCGGGC
GCGCAGATCGGCCCGACCCGCGAGGCCATCATGCAGGCCCTGGAGCCGCTGCACATCCCGGTGGACGTGCAG
ACCAGCTTCGAGGGCAACGCCGGCGCGGTGCAGGACACGCAGAACCAGATGCCCTGGCTGATCCTCCTGGCG
CTGCTGGCGGTGTACATCGTCCTCGGCATCCTCTACGAGAGCTACGTGCACCCGCTGACCATCCTCTCGACC
CTGCCTTCGGCCGGGGTCGGCGCGCTGCTCGCGCTGATCCTCTGCCGCAGCGAGCTGAGCCTGATCGCGCTG
ATCGGCATCATCCTGCTGATCGGCATCGTCAAGAAGAACGCGATCATGATGATCGACTTCGCCCTGGAGGCC
GAGCGCAACCACGGCCTGAGCCCGCGCGAGGCGATCCTCGAGGCCTGCATGATGCGCTTCCGGCCGATCATG
ATGACCACCCTGGCTGCCTTGCTCGGCGCCTTGCCGCTGATCTTCGGCATCGGCGGCGACGCCGCGCTGCGC
CGGCCGCTGGGCATCACCATCGTCGGCGGGCTGATCGGCAGCCAGTTGCTGACCCTGTACACCACCCCGGTG
GTCTACCTCTATCTCGACCGCCTGCGCCACTGGGTCAACCAGAAACGCGGCGTACGCACGGACGGTGCGCTG
GAGACACCCCTATGA
Translation:
MSLSTPFIRRPVATTLLTLALLLAGTLSFGLLPVAPLPNVDFPAIVVSASLPGASPETMASSVATPLERSLG
RIAGISEMTSSSSLGSTTVVLVFDLEKDIDGAAREVQAAINGAMSLLPSGMPNNPSYRKANPSDMPIMVLTL
TSETQSRGEMYDLASTVLAPKLSQVQGVGQVSIGGSSLPAVRVDLNPDAMSQYGLSLDSVRTAIAAANSNGP
KGAVEKDDKHWQVDANDQLRKAREYEPLVIHYNADNGAAVRLGDVAKVSDSVEDVRNAGFSDDLPAVLLIVT
RQPGANIIEATDAIHAQLPVLQELLGPQVKLNVMDDRSPSIRASLEEAELTLLISVALVILVVFLFLRNGRA
TLIPSLAVPVSLIGTFAVMYLCDFSLNNLSLMALIIATGFVVDDAIVVVENIARRIEEGDPPIQAAITGARQ
VGFTVLSMTLSLVAVFIPLLLMGGLTGRLFREFAVTLSAAILVSLVVSLTLTPMLCARLLRPLKRPEGASLA
RRSDRFFAAFMLRYRASLGWALEHSRLMVVIMLACIAMNLWLFVVVPKGFLPQQDSGRLRGYAVADQSISFQ
SLSAKMGEYRKILSSDPAVENVVGFIGGGRWQSSNTGSFFVTLKPIGERDPVEKVLTRLRERIAKVPGAALY
LNAGQDVRLGGRDSNAQYEFTLRSDDLTLLREWAPKVEAAMRKLPQLVDVNSDSQDKGVQTRLVIDRDRAAT
LGINVEMVDAVLNDSFGQRQVSTIFNPLNQYRVVMEVDQQYQQSPEILRQVQVIGNDGQRVPLSAFSHYEPS
RAPLEVNHQGQFAATTLSFNLAPGAQIGPTREAIMQALEPLHIPVDVQTSFEGNAGAVQDTQNQMPWLILLA
LLAVYIVLGILYESYVHPLTILSTLPSAGVGALLALILCRSELSLIALIGIILLIGIVKKNAIMMIDFALEA
ERNHGLSPREAILEACMMRFRPIMMTTLAALLGALPLIFGIGGDAALRRPLGITIVGGLIGSQLLTLYTTPV
VYLYLDRLRHWVNQKRGVRTDGALETPL*
AnnotationID:74GeneID:64
AnnotatorUID: diggins
Modification Date/Time: 2005-03-06 18:06:30
Gene Name:
Confidence Code:3
GeneProduct:putative efflux transporter
Cell Localization:()
Synonyms:PA2526
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(27) Transport of small molecules
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0841,pfam00873,COG3696
Secondary Functional Category(ies):membrane proteins
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAD18350.1| (AL646083) PROBABLE DRUG EFFLUX TRANSMEMBRANE PROTEIN [Ralstonia
            solanacearum]
          Length = 1033

 Score = 1261 bits (3262), Expect = 0.0
 Identities = 646/1018 (63%), Positives = 808/1018 (79%), Gaps = 6/1018 (0%)

>dbj|BAC06609.1| (AB089189) multidrug transporter [Escherichia coli]
          Length = 1025

 Score = 1229 bits (3179), Expect = 0.0
 Identities = 638/1012 (63%), Positives = 785/1012 (77%), Gaps = 7/1012 (0%)

>gb|AAO68437.1| (AE016836) putative RND-family transporter protein [Salmonella
            enterica subsp. enterica serovar Typhi Ty2]
          Length = 1026

 Score = 1208 bits (3126), Expect = 0.0
 Identities = 628/1012 (62%), Positives = 773/1012 (76%), Gaps = 7/1012 (0%)






 
Structural Features:
COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms]
CD-Length = 1009 residues, 100.0% aligned
Score =  973 bits (2517), Expect = 0.0
Identities = 404/1019 (39%), Positives = 593/1019 (58%), Gaps = 14/1019 (1%)

pfam00873, ACR_tran, AcrB/AcrD/AcrF family.
CD-Length = 1017 residues,  99.6% aligned
Score =  901 bits (2330), Expect = 0.0
Identities = 390/1019 (38%), Positives = 590/1019 (57%), Gaps = 17/1019 (1%)

COG3696, COG3696, Putative silver efflux pump 
[Inorganic ion transport and metabolism]
CD-Length = 1027 residues,  99.1% aligned
Score =  439 bits (1131), Expect = 7e-124
Identities = 292/1039 (28%), Positives = 496/1039 (47%), Gaps = 45/1039 (4%)







   
Genomic Context:






   
Comment:


















    ReferenceID:131




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17273




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33087




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:64_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:64
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
127
                           PA2526_tr
                           translation of PA2526
                           1036
                           99.99
                           99.99
                           0
                           5134.0
     

     
     
13008
                           gb|AAG05914.1|AE004680_2
                           (AE004680) probable RND efflux transporter [Pseudomonas aeruginosa PAO1]
                           1036
                           99.99
                           99.99
                           0
                           5134.0
     

     
     
13009
                           emb|CAD18350.1|
                           (AL646083) PROBABLE DRUG EFFLUX TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]
                           1045
                           62.39
                           77.99
                           21
                           3273.0
     

     
     
13014
                           dbj|BAB36307.1|
                           (AP002560) hypothetical protein [Escherichia coli O157:H7]
                           1038
                           61.65
                           76.10
                           15
                           3181.0
     

     
     
13013
                           dbj|BAA15932.1|
                           (D90846) Acriflavin resistance protein F (EnvD protein). [Escherichia coli]
                           1038
                           61.65
                           76.20
                           15
                           3182.0
     

     






      

          
GC ORFID: 43066How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2526Glimmer Score: 

          
Start: 2177466Stop: 2174356

          
Length: 3111


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2526 translation of PA2526Homolog Bit Score 1982.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene1404 (ORF: BLASTX 1158.0), t_PA2527 (ORF: BLASTX 998.0), t_PA1436 (ORF: BLASTX 899.0), psyr_15may02_Scaffold3_revised_gene4945 (ORF: BLASTX 893.0), t_PA2526 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAGCCTGTCCACGCCCTTCATCCGCCGCCCGGTCGCCACCACGCTGCTGACCCTGGCGTTGCTGCTGGCC 
GGCACCCTGTCGTTCGGTCTGCTGCCGGTGGCGCCGCTGCCCAACGTCGATTTTCCGGCCATCGTGGTCAGC 
GCCAGCCTGCCGGGCGCCAGCCCGGAAACCATGGCCTCGTCGGTGGCCACGCCGCTGGAGCGCTCGCTGGGA 
CGGATCGCCGGGATCAGCGAGATGACCTCCAGCAGTTCGCTGGGCTCGACCACCGTGGTGCTCGTGTTCGAC 
CTGGAGAAGGACATCGACGGCGCCGCCCGCGAGGTGCAGGCGGCGATCAACGGCGCGATGAGCCTGCTGCCC 
AGCGGCATGCCGAACAATCCCAGCTACCGCAAGGCCAACCCCTCGGACATGCCGATCATGGTCCTCACCCTG 
ACCTCGGAGACCCAGAGTCGCGGCGAGATGTACGACCTCGCCTCGACCGTGCTGGCGCCGAAGCTGTCGCAG 
GTGCAGGGGGTAGGGCAGGTGAGCATCGGCGGCAGCTCGCTGCCGGCGGTGCGGGTCGACCTCAACCCGGAT 
GCCATGAGCCAGTACGGGCTGTCCCTGGACAGCGTGCGCACGGCCATCGCCGCGGCCAACAGCAACGGCCCC 
AAGGGCGCCGTCGAGAAGGACGACAAGCACTGGCAGGTGGACGCCAACGACCAGTTGCGCAAGGCCCGCGAG 
TACGAGCCGCTGGTGATCCACTACAACGCCGACAACGGCGCCGCGGTGCGCCTCGGCGACGTGGCCAAGGTC 
AGCGACTCGGTGGAGGACGTGCGCAACGCCGGCTTCTCCGACGACCTGCCGGCGGTGCTGCTGATCGTCACC 
CGCCAGCCCGGCGCCAACATCATCGAGGCCACCGACGCCATCCACGCGCAACTGCCGGTGTTGCAGGAACTG 
CTCGGGCCGCAGGTCAAGCTGAACGTGATGGATGATCGCAGCCCGTCGATCCGCGCGTCGCTGGAAGAGGCC 
GAGCTGACCCTGCTGATCTCGGTGGCGCTGGTGATCCTGGTGGTCTTCCTGTTCCTGCGCAACGGCCGCGCC 
ACGCTGATCCCCAGCCTGGCGGTGCCGGTCTCGCTGATCGGCACCTTCGCGGTCATGTACCTGTGCGACTTC 
AGCCTGAACAACCTGTCGCTGATGGCGCTGATCATCGCCACCGGCTTCGTGGTGGACGACGCCATTGTGGTG 
GTGGAAAACATCGCCCGACGCATCGAGGAGGGCGATCCGCCGATCCAGGCGGCGATCACCGGCGCCCGCCAG 
GTCGGTTTCACCGTGTTGTCGATGACGCTCTCGCTGGTCGCGGTGTTCATCCCGCTGCTGCTCATGGGCGGC 
CTCACCGGGCGGTTGTTCCGCGAGTTCGCGGTGACTCTCTCGGCGGCGATCCTGGTGTCCCTGGTGGTATCC 
CTGACCCTCACGCCGATGCTCTGCGCGCGTCTGCTGCGTCCGCTGAAACGGCCCGAGGGCGCCTCCCTGGCG 
CGGCGCAGCGATCGCTTCTTCGCCGCCTTCATGCTGCGCTACCGCGCCAGCCTGGGCTGGGCGCTGGAGCAC 
TCGCGGCTGATGGTGGTGATCATGCTGGCCTGCATCGCCATGAACCTCTGGTTGTTCGTGGTGGTGCCCAAG 
GGCTTCCTCCCGCAGCAGGACTCCGGGCGCCTGCGCGGCTACGCGGTgGCCGACCAGAGCATCTCGTTCCAG 
TCCCTGAGCGCGAAGATGGGCGAGTACCGCAAGATCCTCTCTTCCGATCCGGCGGTGGAAAACGTGGTCGGC 
TTCATCGGCGGCGGCCGCTGGCAGTCGAGCAACACCGGTTCGTTCTTCGTCACCCTCAAGCCGATCGGCGAA 
CGCGACCCGGTGGAGAAGGTCCTCACCCGGCTGCGCGAGCGGATCGCCAAGGTGCCCGGCGCGGCGCTCTAT 
CTCAATGCCGGCCAGGACGTGCGCCTGGGCGGCCGCGACAGCAACGCGCAGTACGAATTCACCCTGCGCAGC 
GACGACCTGACCCTGCTCCGCGAATGGGCGCCGAAGGTCGAGGCGGCGATGCGCAAGCTGCCGCAGCTGGTG 
GACGTCAACAGCGACTCCCAGGACAAGGGCGTGCAGACCCGCCTGGTGATCGACCGCGACCGTGCGGCGACC 
CTGGGGATCAACGTGGAAATGGTCGACGCGGTGCTCAACGATTCCTTCGGCCAGCGCCAGGTGTCGACCATC 
TTCAACCCGCTGAACCAGTACCGGGTGGTGATGGAGGTCGACCAGCAGTACCAGCAGAGCCCGGAGATCCTC 
CGCCAGGTCCAGGTGATCGGCAACGACGGCCAGCGCGTGCCGCTGTCCGCGTTCAGCCACTACGAACCGAGC 
CGGGCACCGCTGGAAGTCAACCACCAGGGCCAGTTCGCCGCCACCACGCTGTCCTTCAACCTGGCGCCGGGC 
GCGCAGATCGGCCCGACCCGCGAGGCCATCATGCAGGCCCTGGAGCCGCTGCACATCCCGGTGGACGTGCAG 
ACCAGCTTCGAGGGCAACGCCGGCGCGGTGCAGGACACGCAGAACCAGATGCCCTGGCTGATCCTCCTGGCG 
CTGCTGGCGGTGTACATCGTCCTCGGCATCCTCTACGAGAGCTACGTGCACCCGCTGACCATCCTCTCGACC 
CTGCCTTCGGCCGGGGTCGGCGCGCTGCTCGCGCTGATCCTCTGCCGCAGCGAGCTGAGCCTGATCGCGCTG 
ATCGGCATCATCCTGCTGATCGGCATCGTCAAGAAGAACGCGATCATGATGATCGACTTCGCCCTGGAGGCC 
GAGCGCAACCACGGCCTGAGCCCGCGCGAGGCGATCCTCGAGGCCTGCATGATGCGCTTCCGGCCGATCATG 
ATGACCACCCTGGCTGCCTTGCTCGGCGCCTTGCCGCTGATCTTCGGCATCGGCGGCGACGCCGCGCTGCGC 
CGGCCGCTGGGCATCACCATCGTCGGCGGGCTGATCGGCAGCCAGTTGCTGACCCTGTACACCACCCCGGTG 
GTCTACCTCTATCTCGACCGCCTGCGCCACTGGGTCAACCAGAAACGCGGCGTACGCACGGACGGTGCGCTG 
GAGACACCCCTATGA