ViewGene
Locus Name:
GeneID:
Location:

GeneID:5639
TrivialName: PA14_48450
AnnotatorUID: nikki
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_48450
PAO1 Ortholog Locus:
Sequence Length:1119
Protein Length:372
Start: 4307897
Stop: 4306779
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
>gi|23062617|ref|ZP_00087389.1| COG2957: Peptidylarginine deiminase and related enzymes[Pseudomonas fluorescens PfO-1] Length = 389 Score = 411 bits (1056), Expect = e-113 Identities = 196/342 (57%), Positives = 243/342 (71%), Gaps = 1/342 (0%) Homology: dbj|BAC70425.1| (AP005032) putative agmatine deiminase [Streptomyces avermitilis MA-4680]
Identities = 136/349 (38%), Positives = 195/349 (55%), Gaps = 20/349 (5%) Actual Start methionine may be located 106 amino acids upstream of predicted start methionine listed here. Coding sequence may overlap with GeneID 4463.
Sequence:
ATGACCCGCAGACATTTCCTCCAGCGACTCGGCGCCAGCGCCGGCCTCGGTGCCGCCCTCACGCTCGGCCTG
GAGTTCGGCTCGCCGCGTGGACAGGCGGCGGCAGCCGATCACTGGCACATGCCCGACGAGCACCTGCCGCAG
GAACGGGTGTTCCTTGCCTATGCCGCGTCCCCGTCGATCTGGAAGGACCTGGCCGAGGACGTGAACCGCAGC
GTCGCCCTGCTGGCCAGGACCATCGCCCGCTACCAGCCGGTCACGCTGCTCTGCCGGCCCACGCAGGAGGCC
GCGGCGCGCCGCGCATGCGGCGGCGCCAACATCGACTACCTGGCGTTGCCGCTGGACGATATCTGGGTCCGC
GACTACGGCGGCTGCTTCGTGCTGAACGGGGAGGGCGAAGCGGGCCTGGTGGATTTCAACTTCAACGGCTGG
GGCGGCAAGCAGCAGGCCGGCAACGATAGCCGCGTCGCCGGCGTGCTAAGCGAGCGACTGGAGGTCCGCTAC
ATCGCCAGCCAACTGACCGGCGAGGGCGGCGGCATCGAAGTGGACGGGCGTGGCACGGCGATCCTCACCGAA
AGTTGCTGGCTCAACGACAATCGCAACCCCGGCATGGACAAGGGCCAGGTCGAGGCCGAATTGAAAGCCCTG
CTCGGCCTGCGCAAGATCGTCTGGCTGCCGGGTATCCGCGGCAGGGACATCACCGATGCGCATGTCGACTTC
TATGCGCGCTTCGTCAGGCCGGGCGTGGTCATCGCCAATCTCGACAACGACCCGGACTCCTACGACTACGCC
GTGACCCGCGAACACCTGGAGATCCTGCGCACAGCCACCGACGCCGACGGTCGCGCGCTGCAGGTGCATACC
CTGTCGCCGCCCCTGAAGCCGCGCCGCGACTACTCGCGAAACAACCCGGACTTCGCCGCCGGCTACATCAAC
TACCTGCCGATCAACGGCGCGGTGATTGCCCCGCAGTTCGGCGACGCCAGCGCCGATCGCCACTGCGGGGAA
TTGCTGGGCCGCCTGTATCCGGGGCGGGACATCGTCCAGCTGAACATCGATCCCATCGCCGCCGGAGGCGGC
GGCATCCATTGCGTGACCAAGCACATGCCACGTGCCTGA
Translation:
MTRRHFLQRLGASAGLGAALTLGLEFGSPRGQAAAADHWHMPDEHLPQERVFLAYAASPSIWKDLAEDVNRS
VALLARTIARYQPVTLLCRPTQEAAARRACGGANIDYLALPLDDIWVRDYGGCFVLNGEGEAGLVDFNFNGW
GGKQQAGNDSRVAGVLSERLEVRYIASQLTGEGGGIEVDGRGTAILTESCWLNDNRNPGMDKGQVEAELKAL
LGLRKIVWLPGIRGRDITDAHVDFYARFVRPGVVIANLDNDPDSYDYAVTREHLEILRTATDADGRALQVHT
LSPPLKPRRDYSRNNPDFAAGYINYLPINGAVIAPQFGDASADRHCGELLGRLYPGRDIVQLNIDPIAAGGG
GIHCVTKHMPRA*
AnnotationID:5641GeneID:5639
AnnotatorUID: danlee
Modification Date/Time: 2005-10-08 16:04:10
Gene Name:
Confidence Code:3
GeneProduct:putative peptidyl-arginine deiminase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(20) Putative enzymes
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam04371, COG2957
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
gi|48729339|ref|ZP_00263090.1|  COG2957: Peptidylarginine deiminase and related enzymes 
[Pseudomonas fluorescens PfO-1]
     Length=372
     Score =  452 bits (1164),  Expect = 7e-126
     Identities = 217/370 (58%), Positives = 271/370 (73%), Gaps = 2/370 (0%)

gi|46312044|ref|ZP_00212644.1|  COG2957: Peptidylarginine deiminase and related enzymes 
[Burkholderia cepacia R18194]
     Length=344
     Score =  363 bits (931),  Expect = 7e-99
     Identities = 185/344 (53%), Positives = 234/344 (68%), Gaps = 7/344 (2%)








 
Structural Features:
pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. 
             CD-Length = 329 residues,  99.7% aligned
             Score =  280 bits (718), Expect = 2e-76

COG2957, Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism].
             CD-Length = 346 residues,  98.0% aligned
             Score =  252 bits (646), Expect = 4e-68






   
Genomic Context:






   
Comment:


















    ReferenceID:11238




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:16942




  
Author/Investigator(s):
        Shirai H, Blundell TL, Mizuguchi K.





  
Title:
        A novel superfamily of enzymes that catalyze the modification of guanidino groups.




  
PubMed:
        11504612


MedLine:
        




    
Source:
Trends Biochem Sci. 2001 Aug;26(8):465-8.






    
Reference Type:Journal 







    
Data:


    		




 
URL:

















    ReferenceID:16943




  
Author/Investigator(s):
        McGraw WT, Potempa J, Farley D, Travis J.





  
Title:
        Purification, characterization, and sequence analysis of a potential virulence factor from Porphyromonas gingivalis, peptidylarginine deiminase.




  
PubMed:
        10377098


MedLine:
        




    
Source:
Infect Immun. 1999 Jul;67(7):3248-56.






    
Reference Type:Journal 







    
Data:


    		




 
URL:

















    ReferenceID:28411




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:5639
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
197336
                           gb|AAQ60922.1|
                           (AE016921) conserved hypothetical protein [Chromobacterium violaceum ATCC 12472]
                           373
                           47.72
                           59.51
                           45
                           903.0
     

     






      

          
GC ORFID: 48641How Found: Glimmer

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: Glimmer Score: 

          
Start: 646011Stop: 647129

          
Length: 1119


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: Homolog Bit Score 

          
Other Homologs:  

          
GC ORF Sequence

           
ATGACCCGCAGACATTTCCTCCAGCGACTCGGCGCCAGCGCCGGCCTCGGTGCCGCCCTCACGCTCGGCCTG 
GAGTTCGGCTCGCCGCGTGGACAGGCGGCGGCAGCCGATCACTGGCACATGCCCGACGAGCACCTGCCGCAG 
GAACGGGTGTTCCTTGCCTATGCCGCGTCCCCGTCGATCTGGAAGGACCTGGCCGAGGACGTGAACCGCAGC 
GTCGCCCTGCTGGCCAGGACCATCGCCCGCTACCAGCCGGTCACGCTGCTCTGCCGGCCCACGCAGGAGGCC 
GCGGCGCGCCGCGCATGCGGCGGCGCCAACATCGACTACCTGGCGTTGCCGCTGGACGATATCTGGGTCCGC 
GACTACGGCGGCTGCTTCGTGCTGAACGGGGAGGGCGAAGCGGGCCTGGTGGATTTCAACTTCAACGGCTGG 
GGCGGCAAGCAGCAGGCCGGCAACGATAGCCGCGTCGCCGGCGTGCTAAGCGAGCGACTGGAGGTCCGCTAC 
ATCGCCAGCCAACTGACCGGCGAGGGCGGCGGCATCGAAGTGGACGGGCGTGGCACGGCGATCCTCACCGAA 
AGTTGCTGGCTCAACGACAATCGCAACCCCGGCATGGACAAGGGCCAGGTCGAGGCCGAATTGAAAGCCCTG 
CTCGGCCTGCGCAAGATCGTCTGGCTGCCGGGTATCCGCGGCAGGGACATCACCGATGCGCATGTCGACTTC 
TATGCGCGCTTCGTCAGGCCGGGCGTGGTCATCGCCAATCTCGACAACGACCCGGACTCCTACGACTACGCC 
GTGACCCGCGAACACCTGGAGATCCTGCGCACAGCCACCGACGCCGACGGTCGCGCGCTGCAGGTGCATACC 
CTGTCGCCGCCCCTGAAGCCGCGCCGCGACTACTCGCGAAACAACCCGGACTTCGCCGCCGGCTACATCAAC 
TACCTGCCGATCAACGGCGCGGTGATTGCCCCGCAGTTCGGCGACGCCAGCGCCGATCGCCACTGCGGGGAA 
TTGCTGGGCCGCCTGTATCCGGGGCGGGACATCGTCCAGCTGAACATCGATCCCATCGCCGCCGGAGGCGGC 
GGCATCCATTGCGTGACCAAGCACATGCCACGTGCCTGA