ViewGene
Locus Name:
GeneID:
Location:

GeneID:5098
TrivialName: PA14_65990
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_65990
PAO1 Ortholog Locus:PA4990
Sequence Length:333
Protein Length:110
Start: 5877500
Stop: 5877832
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08375.1|AE004912_1 (AE004912) SMR multidrug efflux transporter [Pseudomonas aeruginosa PAO1]
Identities = 110/110 (100%), Positives = 110/110 (100%)
Sequence:
ATGACCAATTATCTCTACCTCGCCATCGCCATCGCCGCCGAAGTGGTCGCCACCACCTCGCTGAAAGCCGTC
GCCGGATTCAGCAAGCCACTGCCGCTGCTGCTGGTGGTGGGCGGCTACGTGCTCGCCTTCAGCATGCTCGTG
CTGGTCATGCGCACCCTGCCGGTCGGCGTGGTCTACGCCATCTGGTCCGGGCTCGGCATCGTCCTGGTCAGC
CTGGTGGCGATGTTCGTCTACGGCCAGCGCCTGGACCCCGCGGCCCTCCTCGGTATCGGCCTGATCATCGCC
GGCGTGCTGGTGATCCAGTTGTTCTCCCGCGCTTCGGGGCACTGA
Translation:
MTNYLYLAIAIAAEVVATTSLKAVAGFSKPLPLLLVVGGYVLAFSMLVLVMRTLPVGVVYAIWSGLGIVLVS
LVAMFVYGQRLDPAALLGIGLIIAGVLVIQLFSRASGH*
AnnotationID:5103GeneID:5098
AnnotatorUID: diggins
Modification Date/Time: 2005-03-14 08:08:00
Gene Name:qacH
Confidence Code:2
GeneProduct:putative SMR multidrug efflux transporter
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(3) Antibiotic resistance and susceptibility
Alternate Gene Product Name:putative membrane transporter of cations
Functional Category Confidence Code:5
COGs:COG2076,pfam00893
Secondary Functional Category(ies):transport of small molecules
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO58407.1| (AE016874) multidrug resistance protein [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 110

 Score =  152 bits (385), Expect = 3e-37
 Identities = 72/110 (65%), Positives = 92/110 (83%)

>gb|AAN70497.1|AE016691_5 (AE016792) multidrug efflux SMR transporter [Pseudomonas putida
           KT2440]
          Length = 110

 Score =  145 bits (367), Expect = 3e-35
 Identities = 70/110 (63%), Positives = 90/110 (81%)

>emb|CAE35887.1| (BX640448) putative mebrane transport protein [Bordetella
           bronchiseptica]
          Length = 110

 Score =  123 bits (308), Expect = 2e-28
 Identities = 56/110 (50%), Positives = 85/110 (77%)






 
Structural Features:
COG2076, EmrE, Membrane transporters of cations and cationic drugs 
[Inorganic ion transport and metabolism]
CD-Length = 106 residues, 100.0% aligned
Score = 82.0 bits (203), Expect = 1e-17
Identities = 49/106 (46%), Positives = 74/106 (69%)

pfam00893, Multi_Drug_Res, Small Multidrug Resistance protein.
CD-Length = 93 residues,  98.9% aligned
Score = 68.6 bits (168), Expect = 1e-13
Identities = 36/92 (39%), Positives = 60/92 (65%)






   
Genomic Context:






   
Comment:


















    ReferenceID:10196




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:27340




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:35072




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:5098_cdd.html


    		




 
URL:

















    ReferenceID:35878




  
Author/Investigator(s):
        Heir E, Sundheim G, Holck AL.





  
Title:
        The Staphylococcus qacH gene product: a new member of the SMR family encoding multidrug resistance.




  
PubMed:
        9631545


MedLine:
        




    
Source:
FEMS Microbiol Lett. 1998 Jun 1;163(1):49-56.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9631545









           
Homologs By Global Alignment 

           

       



     
Gene ID:5098
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
7506
                           PA4990_tr
                           translation of PA4990
                           110
                           99.99
                           99.99
                           0
                           528.0
     

     
     
193158
                           gb|AAG08375.1|AE004912_1
                           (AE004912) SMR multidrug efflux transporter [Pseudomonas aeruginosa PAO1]
                           110
                           99.99
                           99.99
                           0
                           528.0
     

     
     
193159
                           gb|AAO58407.1|
                           (AE016874) multidrug resistance protein [Pseudomonas syringae pv. tomato str. DC3000]
                           110
                           65.45
                           83.63
                           0
                           385.0
     

     
     
193160
                           gb|AAN70497.1|AE016691_5
                           (AE016792) multidrug efflux SMR transporter [Pseudomonas putida KT2440]
                           110
                           63.63
                           81.81
                           0
                           367.0
     

     
     
193161
                           emb|CAE14940.1|
                           (BX571867) unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]
                           110
                           58.18
                           77.27
                           0
                           320.0
     

     






      

          
GC ORFID: 48100How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4990Glimmer Score: 

          
Start: 5141183Stop: 5141515

          
Length: 333


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4990 translation of PA4990Homolog Bit Score 207.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene3675 (ORF: BLASTX 155.0), t_PA4990 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCAATTATCTCTACCTCGCCATCGCCATCGCCGCCGAAGTGGTCGCCACCACCTCGCTGAAAGCCGTC 
GCCGGATTCAGCAAGCCACTGCCGCTGCTGCTGGTGGTGGGCGGCTACGTGCTCGCCTTCAGCATGCTCGTG 
CTGGTCATGCGCACCCTGCCGGTCGGCGTGGTCTACGCCATCTGGTCCGGGCTCGGCATCGTCCTGGTCAGC 
CTGGTGGCGATGTTCGTCTACGGCCAGCGCCTGGACCCCGCGGCCCTCCTCGGTATCGGCCTGATCATCGCC 
GGCGTGCTGGTGATCCAGTTGTTCTCCCGCGCTTCGGGGCACTGA