ViewGene
Locus Name:
GeneID:
Location:

GeneID:4932
TrivialName: PA14_44520
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_44520
PAO1 Ortholog Locus:PA1541
Sequence Length:369
Protein Length:122
Start: 3964572
Stop: 3964940
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04930.1|AE004582_8 (AE004582) probable drug efflux transporter [Pseudomonas aeruginosa PAO1]
Identities = 121/122 (99%), Positives = 121/122 (99%)
Sequence:
ATGCGTTCCTGGATCTATCTGTTACTGGCTATCGGCGCCGAAGTGATCGGCACCACCTCGATGAAACTGGCC
GCCACCCACGCCCCTGTCGCAGGCATGCTGCTGATGTACGGGATGATCGGCCTGTCCTATTTCTTCCTCGCC
CTGGCGGTCAAGCGTGTCCCCGTCGGAGTCGCCTACGCCCTTTGGGAAGGCATTGGCATCGTCCTGATCACG
GCGGTCAGCGTCGCCTGGCTGGGCGAAAGCATCGGCCTGTACAAGGCCGTCGGCCTCGGCGTGATGATCGCC
GGCATCCTGCTGATCAAGTCCGGCACCCGCAACGCCAGCGGCACGCCGGCGCAGCCCCGTGGGGAGGCCGTC
ACATGCTGA
Translation:
MRSWIYLLLAIGAEVIGTTSMKLAATHAPVAGMLLMYGMIGLSYFFLALAVKRVPVGVAYALWEGIGIVLIT
AVSVAWLGESIGLYKAVGLGVMIAGILLIKSGTRNASGTPAQPRGEAVTC*
AnnotationID:4937GeneID:4932
AnnotatorUID: diggins
Modification Date/Time: 2005-02-25 09:09:48
Gene Name:
Confidence Code:3
GeneProduct:putative drug efflux transporter
Cell Localization:()
Synonyms:ydgF
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(27) Transport of small molecules
Alternate Gene Product Name:putative membrane transporter of cations and cationic drugs
Functional Category Confidence Code:5
COGs:COG2076,pfam00893
Secondary Functional Category(ies):membrane protein
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAC90880.1| (AJ414151) putative integral membrane protein [Yersinia pestis
           CO92]
          Length = 154

 Score =  118 bits (295), Expect = 7e-27
 Identities = 63/112 (56%), Positives = 78/112 (69%), Gaps = 4/112 (3%)

>gb|AAP17092.1| (AE016983) possible chaperone [Shigella flexneri 2a str. 2457T]
          Length = 121

 Score =  112 bits (279), Expect = 5e-25
 Identities = 59/105 (56%), Positives = 71/105 (67%)

>gb|AAC74672.1| (AE000255) possible chaperone [Escherichia coli K12]
          Length = 121

 Score =  112 bits (279), Expect = 5e-25
 Identities = 59/105 (56%), Positives = 71/105 (67%)






 
Structural Features:
COG2076, EmrE, Membrane transporters of cations and cationic drugs 
[Inorganic ion transport and metabolism]
CD-Length = 106 residues, 100.0% aligned
Score = 89.0 bits (221), Expect = 1e-19
Identities = 49/106 (46%), Positives = 71/106 (66%)

pfam00893, Multi_Drug_Res, Small Multidrug Resistance protein. 
CD-Length = 93 residues,  98.9% aligned
Score = 72.1 bits (177), Expect = 2e-14
Identities = 36/92 (39%), Positives = 55/92 (59%)






   
Genomic Context:






   
Comment:


















    ReferenceID:9864




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:27005




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37314




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4932_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:4932
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
7335
                           PA1541_tr
                           translation of PA1541
                           122
                           99.18
                           99.18
                           0
                           601.0
     

     
     
190825
                           gb|AAG04930.1|AE004582_8
                           (AE004582) probable drug efflux transporter [Pseudomonas aeruginosa PAO1]
                           122
                           99.18
                           99.18
                           0
                           601.0
     

     
     
190839
                           emb|CAD01832.1|
                           (AL627270) putative conserved membrane protein [Salmonella enterica subsp. enterica serovar Typhi]
                           124
                           50.00
                           61.29
                           6
                           274.0
     

     
     
190838
                           gb|AAO69046.1|
                           (AE016838) putative conserved membrane protein [Salmonella enterica subsp. enterica serovar Typhi Ty2]
                           124
                           50.00
                           61.29
                           6
                           274.0
     

     
     
190837
                           gb|AAL20401.1|
                           (AE008764) putative membrane transporter of cations and cationic drugs [Salmonella typhimurium LT2]
                           124
                           50.00
                           61.29
                           6
                           274.0
     

     






      

          
GC ORFID: 47934How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1541Glimmer Score: 

          
Start: 989337Stop: 988969

          
Length: 369


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1541 translation of PA1541Homolog Bit Score 236.0

          
Other Homologs:  t_PA1541 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGTTCCTGGATCTATCTGTTACTGGCTATCGGCGCCGAAGTGATCGGCACCACCTCGATGAAACTGGCC 
GCCACCCACGCCCCTGTCGCAGGCATGCTGCTGATGTACGGGATGATCGGCCTGTCCTATTTCTTCCTCGCC 
CTGGCGGTCAAGCGTGTCCCCGTCGGAGTCGCCTACGCCCTTTGGGAAGGCATTGGCATCGTCCTGATCACG 
GCGGTCAGCGTCGCCTGGCTGGGCGAAAGCATCGGCCTGTACAAGGCCGTCGGCCTCGGCGTGATGATCGCC 
GGCATCCTGCTGATCAAGTCCGGCACCCGCAACGCCAGCGGCACGCCGGCGCAGCCCCGTGGGGAGGCCGTC 
ACATGCTGA