ViewGene
Locus Name:
GeneID:
Location:

GeneID:486
TrivialName: PA14_30660
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_30660
PAO1 Ortholog Locus:PA2585
Sequence Length:1827
Protein Length:608
Start: 2656149
Stop: 2657975
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05973.1|AE004687_2 (AE004687) excinuclease ABC subunit C [Pseudomonas aeruginosa PAO1]
Identities = 607/608 (99%), Positives = 608/608 (100%)
Sequence:
ATGAGCGCCGTTTTCGACGCGAGCGCCTTCCTCGCTACCTGTAGCAATCGTCCGGGCGTCTACCGCATGTTC
GATGCGGACGCCAAGCTTCTCTACGTGGGCAAGGCGAAGAGCCTGAAGAAGCGCCTGGCCAGCTATTTCCGC
AAGTCCGGCCTGGCGCCGAAGACCGCTGCGCTGGTGGCGCGCATCGCCCAGGTGGAAACCACCATCACCGCC
AATGAAACCGAGGCGTTGCTGCTGGAGCAGACGCTGATCAAGGAGTGGCGGCCGCCCTACAACATCCTGCTG
CGGGACGACAAGTCCTATCCCTTCGTGTTCCTCTCCAGCGAGGATGAGTATCCGCGGCTGTCCCTGCACCGT
GGCGCGAAGAAGCGCAAGGGGCGTTACTTCGGTCCCTATCCGAGCGCGGGAGCGATCCGCGAGAGCCTCAAC
CTGCTGCAGAAGGCGTTTCTCGTCCGCCAGTGCGAGGACAGCTATTTCCGCAACCGTACGCGGCCCTGCCTG
CAATACCAGATCAAGCGCTGCAAGGGGCCCTGCGTGGGACTGGTCAGTCCTGAGGAGTACGCCGAGGACGTG
CGCCACTCGGTGATGTTCCTCGAAGGAAGGAGCAACGCGCTGGCCGACGAGCTGAACGTCGGCATGGAGCAG
GCGGCGATGCGCCTGGACTTCGAGAAGGCGGCGGAGTTGCGCGACCAGGTGGCGATCCTGCGGCGGGTCCAG
GACCAGCAGAGCATGGAAGGTGGCAACGGCGACGTCGACATCGTCGCCGCCATCGTCACCCCTGGCGGCGCT
TGCGTACACCTGATCAGCGTACGCGGCGGGCGGGTGCTGGGCAGCAAGAACTTCTTCCCGCAGGTCGCGATC
GAGGAGGAGGTGGGCGAAGTGCTGCTGGCGTTCCTTGGCCAGTACTATCTCAGCCACCAGGAGCGCGACCTG
CCGGCGGAGTTGATCGTCAACGTGACGCACGAGGATTTCCCGGTGCTGGTTTCGGCGATCGCCGAAGCGCGA
GGCCGCGAACTGGAGATCAGCTACCGGGTGCGTGGTACCCGCGCCCGCTGGCAGCAACTGGCGGTGACCAAC
GCCGAACAGGCCCTGGGCGCACGCCTGGCCAACCGCCAGCATGTGGCGGCACGCTTCGAAGCCCTTGCCGAG
GCGCTCGACCTGGCGGAGCCGCCGCAACGCCTGGAGTGCTTCGATATCAGTCACTCCAGCGGCGAGGCCACC
GTGGCTTCCTGCGTGGTGTTCGGCCCGGAAGGGCCGCTGAAGTCGGACTATCGCCGCTACAACATCGAAGGC
GTCACGGCCGGCGACGACTACGCGGCGATGCACCAGGCGCTGACCCGCCGCTTCAGTCGCCTGAAGGACGGC
GAGGGGAAGATGCCCGACATTCTCCTGGTGGATGGCGGCAAGGGGCAATTGGCCATGGCCCAGGAGGTGCTC
CAGGAACTGGCGGTCGCCGGTCTGATCCTGCTCGGCGTGGCCAAGGGCGTGACCCGCAAGCCGGGGCTGGAA
ACCCTCTACCTGAACGATGCCTCCCACGAGTTCACCCTGCCGGCCGATTCGCCGGCGCTGCACCTGATCCAG
CAGATACGTGACGAAGCGCACCGTTTCGCCATCACCGGCCACCGTGCGCGGCGCGGCAAGGCACGGCGGACG
TCGACGCTGGAGGACGTCCCTGGCGTCGGCCCGAAACGTCGGCGCGATCTGCTCAAGCATTTCGGCGGGTTG
CAGGAATTGTCGCGGGCGAGTATCGATGAACTGGCCAAAGCCCCCGGTATCAGTAAAAAGCTTGCCGAGCAG
ATTTATGCCGTCCTGCACAGCGAGTAG
Translation:
MSAVFDASAFLATCSNRPGVYRMFDADAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITA
NETEALLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAGAIRESLN
LLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVMFLEGRSNALADELNVGMEQ
AAMRLDFEKAAELRDQVAILRRVQDQQSMEGGNGDVDIVAAIVTPGGACVHLISVRGGRVLGSKNFFPQVAI
EEEVGEVLLAFLGQYYLSHQERDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTN
AEQALGARLANRQHVAARFEALAEALDLAEPPQRLECFDISHSSGEATVASCVVFGPEGPLKSDYRRYNIEG
VTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVAGLILLGVAKGVTRKPGLE
TLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARRGKARRTSTLEDVPGVGPKRRRDLLKHFGGL
QELSRASIDELAKAPGISKKLAEQIYAVLHSE*
AnnotationID:495GeneID:486
AnnotatorUID: diggins
Modification Date/Time: 2005-03-07 08:08:52
Gene Name:uvrC
Confidence Code:2
GeneProduct:excinuclease ABC subunit C
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(11) DNA replication, recombination, modification and repair
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0322
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAA98758.1| (L29642) UVR excinuclease subunit C [Pseudomonas fluorescens]
          Length = 607

 Score = 1045 bits (2703), Expect = 0.0
 Identities = 523/608 (86%), Positives = 562/608 (92%), Gaps = 1/608 (0%)

>gb|AAO56513.1| (AE016866) excinuclease ABC, C subunit [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 607

 Score = 1024 bits (2647), Expect = 0.0

>gb|AAN54913.1|AE015629_7 (AE015629) excinuclease ABC, C subunit [Shewanella oneidensis MR-1]
          Length = 609

 Score =  639 bits (1649), Expect = 0.0
 Identities = 321/609 (52%), Positives = 436/609 (71%), Gaps = 6/609 (0%)








 
Structural Features:
COG0322, UvrC, Nuclease subunit of the excinuclease complex 
[DNA replication, recombination, and repair]
CD-Length = 581 residues,  99.8% aligned
Score =  663 bits (1711), Expect = 0.0
Identities = 308/603 (51%), Positives = 406/603 (67%), Gaps = 24/603 (3%)








   
Genomic Context:






   
Comment:


















    ReferenceID:975




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:18117




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33156




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:486_cdd.html


    		




 
URL:

















    ReferenceID:34536




  
Author/Investigator(s):
        Ozawa Y, Tanimoto K, Fujimoto S, Tomita H, Ike Y.





  
Title:
        Cloning and genetic analysis of the UV resistance determinant (uvr) encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pAD1.




  
PubMed:
        9393713


MedLine:
        




    
Source:
J Bacteriol. 1997 Dec;179(23):7468-75.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=9393713

















    ReferenceID:34537




  
Author/Investigator(s):
        Gopalakrishnan AS, Chen YC, Temkin M, Dowhan W.





  
Title:
        Structure and expression of the gene locus encoding the phosphatidylglycerophosphate synthase of Escherichia coli.




  
PubMed:
        3003065


MedLine:
        




    
Source:
J Biol Chem. 1986 Jan 25;261(3):1329-38.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3003065

















    ReferenceID:34538




  
Author/Investigator(s):
        Forster JW, Strike P.





  
Title:
        Organisation and control of the Escherichia coli uvrC gene.





  
PubMed:
        2993106


MedLine:
        




    
Source:
Gene. 1985;35(1-2):71-82.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2993106

















    ReferenceID:34539




  
Author/Investigator(s):
        Sancar GB, Sancar A, Rupp WD.





  
Title:
        Sequences of the E. coli uvrC gene and protein.




  
PubMed:
        6330676


MedLine:
        




    
Source:
Nucleic Acids Res. 1984 Jun 11;12(11):4593-608.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6330676

















    ReferenceID:34540




  
Author/Investigator(s):
        Sharma S, Dowhan W, Moses RE.





  
Title:
        Molecular structure of uvrC gene of Escherichia coli: identification of DNA sequences required for transcription of the uvrC gene.




  
PubMed:
        6292835


MedLine:
        




    
Source:
Nucleic Acids Res. 1982 Sep 11;10(17):5209-21.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=6292835









           
Homologs By Global Alignment 

           

       



     
Gene ID:486
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
851
                           PA2585_tr
                           translation of PA2585
                           608
                           99.83
                           99.99
                           0
                           3081.0
     

     
     
35384
                           gb|AAG05973.1|AE004687_2
                           (AE004687) excinuclease ABC subunit C [Pseudomonas aeruginosa PAO1]
                           608
                           99.83
                           99.99
                           0
                           3081.0
     

     
     
35385
                           gb|AAA98758.1|
                           (L29642) UVR excinuclease subunit C [Pseudomonas fluorescens]
                           608
                           86.01
                           92.43
                           1
                           2705.0
     

     
     
35386
                           gb|AAO56513.1|
                           (AE016866) excinuclease ABC, C subunit [Pseudomonas syringae pv. tomato str. DC3000]
                           608
                           84.04
                           91.11
                           1
                           2649.0
     

     
     
35387
                           gb|AAN69682.1|AE016604_4
                           (AE016789) excinuclease ABC, C subunit [Pseudomonas putida KT2440]
                           608
                           83.38
                           89.80
                           1
                           2612.0
     

     






      

          
GC ORFID: 43488How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2585Glimmer Score: 

          
Start: 2297777Stop: 2295951

          
Length: 1827


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA2585 translation of PA2585Homolog Bit Score 1191.0

          
Other Homologs:  t_PA2585 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAGCGCCGTTTTCGACGCGAGCGCCTTCCTCGCTACCTGTAGCAATCGTCCGGGCGTCTACCGCATGTTC 
GATGCGGACGCCAAGCTTCTCTACGTGGGCAAGGCGAAGAGCCTGAAGAAGCGCCTGGCCAGCTATTTCCGC 
AAGTCCGGCCTGGCGCCGAAGACCGCTGCGCTGGTGGCGCGCATCGCCCAGGTGGAAACCACCATCACCGCC 
AATGAAACCGAGGCGTTGCTGCTGGAGCAGACGCTGATCAAGGAGTGGCGGCCGCCCTACAACATCCTGCTG 
CGGGACGACAAGTCCTATCCCTTCGTGTTCCTCTCCAGCGAGGATGAGTATCCGCGGCTGTCCCTGCACCGT 
GGCGCGAAGAAGCGCAAGGGGCGTTACTTCGGTCCCTATCCGAGCGCGGGAGCGATCCGCGAGAGCCTCAAC 
CTGCTGCAGAAGGCGTTTCTCGTCCGCCAGTGCGAGGACAGCTATTTCCGCAACCGTACGCGGCCCTGCCTG 
CAATACCAGATCAAGCGCTGCAAGGGGCCCTGCGTGGGACTGGTCAGTCCTGAGGAGTACGCCGAGGACGTG 
CGCCACTCGGTGATGTTCCTCGAAGGAAGGAGCAACGCGCTGGCCGACGAGCTGAACGTCGGCATGGAGCAG 
GCGGCGATGCGCCTGGACTTCGAGAAGGCGGCGGAGTTGCGCGACCAGGTGGCGATCCTGCGGCGGGTCCAG 
GACCAGCAGAGCATGGAAGGTGGCAACGGCGACGTCGACATCGTCGCCGCCATCGTCACCCCTGGCGGCGCT 
TGCGTACACCTGATCAGCGTACGCGGCGGGCGGGTGCTGGGCAGCAAGAACTTCTTCCCGCAGGTCGCGATC 
GAGGAGGAGGTGGGCGAAGTGCTGCTGGCGTTCCTTGGCCAGTACTATCTCAGCCACCAGGAGCGCGACCTG 
CCGGCGGAGTTGATCGTCAACGTGACGCACGAGGATTTCCCGGTGCTGGTTTCGGCGATCGCCGAAGCGCGA 
GGCCGCGAACTGGAGATCAGCTACCGGGTGCGTGGTACCCGCGCCCGCTGGCAGCAACTGGCGGTGACCAAC 
GCCGAACAGGCCCTGGGCGCACGCCTGGCCAACCGCCAGCATGTGGCGGCACGCTTCGAAGCCCTTGCCGAG 
GCGCTCGACCTGGCGGAGCCGCCGCAACGCCTGGAGTGCTTCGATATCAGTCACTCCAGCGGCGAGGCCACC 
GTGGCTTCCTGCGTGGTGTTCGGCCCGGAAGGGCCGCTGAAGTCGGACTATCGCCGCTACAACATCGAAGGC 
GTCACGGCCGGCGACGACTACGCGGCGATGCACCAGGCGCTGACCCGCCGCTTCAGTCGCCTGAAGGACGGC 
GAGGGGAAGATGCCCGACATTCTCCTGGTGGATGGCGGCAAGGGGCAATTGGCCATGGCCCAGGAGGTGCTC 
CAGGAACTGGCGGTCGCCGGTCTGATCCTGCTCGGCGTGGCCAAGGGCGTGACCCGCAAGCCGGGGCTGGAA 
ACCCTCTACCTGAACGATGCCTCCCACGAGTTCACCCTGCCGGCCGATTCGCCGGCGCTGCACCTGATCCAG 
CAGATACGTGACGAAGCGCACCGTTTCGCCATCACCGGCCACCGTGCGCGGCGCGGCAAGGCACGGCGGACG 
TCGACGCTGGAGGACGTCCCTGGCGTCGGCCCGAAACGTCGGCGCGATCTGCTCAAGCATTTCGGCGGGTTG 
CAGGAATTGTCGCGGGCGAGTATCGATGAACTGGCCAAAGCCCCCGGTATCAGTAAAAAGCTTGCCGAGCAG 
ATTTATGCCGTCCTGCACAGCGAGTAG