ViewGene
Locus Name:
GeneID:
Location:

GeneID:4754
TrivialName: PA14_63020
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_63020
PAO1 Ortholog Locus:PA4764
Sequence Length:405
Protein Length:134
Start: 5624008
Stop: 5623604
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08150.1|AE004890_3 (AE004890) ferric uptake regulation protein [Pseudomonas aeruginosa PAO1]
Identities = 134/134 (100%), Positives = 134/134 (100%)
Sequence:
ATGGTTGAAAATAGCGAACTTCGAAAAGCCGGCCTTAAAGTGACCCTGCCGCGGGTCAAGATCCTGCAGATG
CTCGACTCGGCCGAGCAACGCCACATGAGCGCCGAAGACGTGTACAAGGCGCTGATGGAAGCAGGCGAGGAC
GTGGGCCTGGCAACCGTCTATCGGGTGCTGACCCAGTTCGAGGCCGCCGGCCTGGTGGTGCGTCACAACTTC
GATGGCGGCCATGCCGTGTTCGAGCTCGCCGATAGCGGCCACCACGACCACATGGTCTGCGTCGATACCGGC
GAGGTGATCGAGTTCATGGATGCGGAAATCGAGAAGCGCCAGAAGGAAATCGTCCGCGAGCGCGGCTTCGAG
CTGGTCGATCACAATCTGGTGCTCTACGTGCGCAAGAAGAAGTAG
Translation:
MVENSELRKAGLKVTLPRVKILQMLDSAEQRHMSAEDVYKALMEAGEDVGLATVYRVLTQFEAAGLVVRHNF
DGGHAVFELADSGHHDHMVCVDTGEVIEFMDAEIEKRQKEIVRERGFELVDHNLVLYVRKKK*
AnnotationID:4759GeneID:4754
AnnotatorUID: diggins
Modification Date/Time: 2005-03-09 11:11:50
Gene Name:fur
Confidence Code:1
GeneProduct:ferric uptake regulation protein
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam01475,COG0735
Secondary Functional Category(ies):inorganic ion transport and metabolism
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70302.1|AE016671_3 (AE016791) transcriptional regulator Fur [Pseudomonas putida
           KT2440]
          Length = 134

 Score =  251 bits (640), Expect = 6e-67
 Identities = 127/134 (94%), Positives = 128/134 (95%)

>gb|AAC19097.1| (AF065399) ferric uptake regulator [Pseudomonas stutzeri]
          Length = 134

 Score =  243 bits (621), Expect = 1e-64
 Identities = 120/133 (90%), Positives = 127/133 (95%)

>gb|AAN79243.1|AE016757_147 (AE016757) Ferric uptake regulation protein [Escherichia coli
           CFT073]
          Length = 148

 Score =  163 bits (413), Expect = 1e-40
 Identities = 74/126 (58%), Positives = 98/126 (77%)






 
Structural Features:
pfam01475, FUR, Ferric uptake regulator family.
CD-Length = 120 residues, 100.0% aligned
Score =  150 bits (381), Expect = 4e-38
Identities = 62/121 (51%), Positives = 86/121 (71%), Gaps = 1/121 (0%)

COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins 
[Inorganic ion transport and metabolism]
CD-Length = 145 residues,  85.5% aligned
Score =  132 bits (333), Expect = 1e-32
Identities = 59/125 (47%), Positives = 84/125 (67%), Gaps = 1/125 (0%)






   
Genomic Context:






   
Comment:


















    ReferenceID:9509




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:26649




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37681




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4754_cdd.html


    		




 
URL:

















    ReferenceID:37712




  
Author/Investigator(s):
        Ochsner UA, Vasil AI, Johnson Z, Vasil ML.





  
Title:
        Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA.




  
PubMed:
        9973334


MedLine:
        




    
Source:
J Bacteriol. 1999 Feb;181(4):1099-109.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9973334

















    ReferenceID:37713




  
Author/Investigator(s):
        Prince RW, Cox CD, Vasil ML.





  
Title:
        Coordinate regulation of siderophore and exotoxin A production: molecular cloning and sequencing of the Pseudomonas aeruginosa fur gene.




  
PubMed:
        8478325


MedLine:
        




    
Source:
J Bacteriol. 1993 May;175(9):2589-98.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8478325

















    ReferenceID:37714




  
Author/Investigator(s):
        Vasil ML, Ochsner UA.





  
Title:
        The response of Pseudomonas aeruginosa to iron: genetics, biochemistry and virulence.




  
PubMed:
        10564483


MedLine:
        




    
Source:
Mol Microbiol. 1999 Nov;34(3):399-413.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10564483









           
Homologs By Global Alignment 

           

       



     
Gene ID:4754
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
7125
                           PA4764_tr
                           translation of PA4764
                           134
                           99.99
                           99.99
                           0
                           680.0
     

     
     
187109
                           gb|AAG08150.1|AE004890_3
                           (AE004890) ferric uptake regulation protein [Pseudomonas aeruginosa PAO1]
                           134
                           99.99
                           99.99
                           0
                           680.0
     

     
     
187110
                           gb|AAC05679.1|
                           (AF050676) ferric uptake regulator [Pseudomonas aeruginosa]
                           134
                           99.99
                           99.99
                           0
                           680.0
     

     
     
187111
                           gb|AAA25820.1|
                           (L00604) ferric uptake regulator [Pseudomonas aeruginosa]
                           134
                           99.99
                           99.99
                           0
                           680.0
     

     
     
187112
                           gb|AAN70302.1|AE016671_3
                           (AE016791) transcriptional regulator Fur [Pseudomonas putida KT2440]
                           134
                           94.77
                           95.52
                           0
                           640.0
     

     






      

          
GC ORFID: 47756How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4764Glimmer Score: 

          
Start: 4887688Stop: 4887284

          
Length: 405


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA4764 translation of PA4764Homolog Bit Score 266.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5473 (ORF: BLASTX 234.0), t_PA4764 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGGTTGAAAATAGCGAACTTCGAAAAGCCGGCCTTAAAGTGACCCTGCCGCGGGTCAAGATCCTGCAGATG 
CTCGACTCGGCCGAGCAACGCCACATGAGCGCCGAAGACGTGTACAAGGCGCTGATGGAAGCAGGCGAGGAC 
GTGGGCCTGGCAACCGTCTATCGGGTGCTGACCCAGTTCGAGGCCGCCGGCCTGGTGGTGCGTCACAACTTC 
GATGGCGGCCATGCCGTGTTCGAGCTCGCCGATAGCGGCCACCACGACCACATGGTCTGCGTCGATACCGGC 
GAGGTGATCGAGTTCATGGATGCGGAAATCGAGAAGCGCCAGAAGGAAATCGTCCGCGAGCGCGGCTTCGAG 
CTGGTCGATCACAATCTGGTGCTCTACGTGCGCAAGAAGAAGTAG