ViewGene
Locus Name:
GeneID:
Location:

GeneID:4586
TrivialName: PA14_05520
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_05520
PAO1 Ortholog Locus:PA0424
Sequence Length:444
Protein Length:147
Start: 486500
Stop: 486057
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAO40258.1| (AY190295) MexR [Pseudomonas aeruginosa]
Identities = 147/147 (100%), Positives = 147/147 (100%)
Sequence:
ATGAACTACCCCGTGAATCCCGACCTGATGCCCGCGCTGATGGCGGTCTTCCAGCATGTACGGACGCGCATC
CAGAGCGAGCTCGATTGCCAGCGACTCGACCTGACCCCGCCCGACGTCCATGTATTGAAGCTTATCGACGAA
CAACGCGGGCTGAACCTGCAGGACCTGGGACGCCAGATGTGCCGCGACAAGGCACTGATCACCCGGAAGATC
CGCGAGCTGGAGGGAAGAAACCTGGTCCGCCGCGAGCGCAACCCCAGCGACCAGCGCAGCTTCCAGCTCTTC
CTCACCGACGAGGGGCTGGCCATCCACCAGCATGCGGAAGCCATCATGTCACGCGTGCATGACGAGTTGTTT
GCCCCGCTCACCCCGGAGGAACAAGCCACCCTGGTGCATCTCCTCGACCAATGCCTGGCCGCGCAACCGCTT
GAGGATATTTAA
Translation:
MNYPVNPDLMPALMAVFQHVRTRIQSELDCQRLDLTPPDVHVLKLIDEQRGLNLQDLGRQMCRDKALITRKI
RELEGRNLVRRERNPSDQRSFQLFLTDEGLAIHQHAEAIMSRVHDELFAPLTPEEQATLVHLLDQCLAAQPL
EDI*
AnnotationID:4592GeneID:4586
AnnotatorUID: diggins
Modification Date/Time: 2005-03-25 09:09:17
Gene Name:mexR
Confidence Code:1
GeneProduct: multidrug resistance operon repressor MexR
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam01047,smart00347
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:






 
Structural Features:
pfam01047, MarR, MarR family. 
CD-Length = 104 residues, 100.0% aligned
Score = 94.5 bits (235), Expect = 4e-21
Identities = 34/104 (32%), Positives = 56/104 (53%)

smart00347, HTH_MARR, helix_turn_helix multiple antibiotic 
resistance protein
CD-Length = 101 residues,  99.0% aligned
Score = 87.6 bits (217), Expect = 5e-19
Identities = 35/100 (35%), Positives = 59/100 (59%)






   
Genomic Context:






   
Comment:


















    ReferenceID:9173




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:26314




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33749




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4586_cdd.html


    		




 
URL:

















    ReferenceID:35364




  
Author/Investigator(s):
        Poole K, Tetro K, Zhao Q, Neshat S, Heinrichs DE, Bianco N.





  
Title:
        Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression.




  
PubMed:
        8878574


MedLine:
        




    
Source:
Antimicrob Agents Chemother. 1996 Sep;40(9):2021-8.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8878574









           
Homologs By Global Alignment 

           

       



     
Gene ID:4586
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
184936
                           gb|AAO40258.1|
                           (AY190295) MexR [Pseudomonas aeruginosa]
                           147
                           99.99
                           99.99
                           0
                           758.0
     

     
     
184937
                           gb|AAO40257.1|
                           (AY190294) MexR [Pseudomonas aeruginosa]
                           147
                           99.99
                           99.99
                           0
                           758.0
     

     
     
184938
                           gb|AAO40256.1|
                           (AY190293) MexR [Pseudomonas aeruginosa]
                           147
                           99.99
                           99.99
                           0
                           758.0
     

     
     
184939
                           gb|AAO40255.1|
                           (AY190292) MexR [Pseudomonas aeruginosa]
                           147
                           99.99
                           99.99
                           0
                           758.0
     

     
     
6953
                           PA0424_tr
                           translation of PA0424
                           147
                           99.31
                           99.31
                           0
                           751.0
     

     






      

          
GC ORFID: 47588How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0424Glimmer Score: 

          
Start: 6287842Stop: 6287399

          
Length: 444


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA0424 translation of PA0424Homolog Bit Score 293.0

          
Other Homologs:  t_PA0424 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACTACCCCGTGAATCCCGACCTGATGCCCGCGCTGATGGCGGTCTTCCAGCATGTACGGACGCGCATC 
CAGAGCGAGCTCGATTGCCAGCGACTCGACCTGACCCCGCCCGACGTCCATGTATTGAAGCTTATCGACGAA 
CAACGCGGGCTGAACCTGCAGGACCTGGGACGCCAGATGTGCCGCGACAAGGCACTGATCACCCGGAAGATC 
CGCGAGCTGGAGGGAAGAAACCTGGTCCGCCGCGAGCGCAACCCCAGCGACCAGCGCAGCTTCCAGCTCTTC 
CTCACCGACGAGGGGCTGGCCATCCACCAGCATGCGGAAGCCATCATGTCACGCGTGCATGACGAGTTGTTT 
GCCCCGCTCACCCCGGAGGAACAAGCCACCCTGGTGCATCTCCTCGACCAATGCCTGGCCGCGCAACCGCTT 
GAGGATATTTAA