ViewGene
Locus Name:
GeneID:
Location:

GeneID:4509
TrivialName: PA14_17190
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_17190
PAO1 Ortholog Locus:PA3645
Sequence Length:441
Protein Length:146
Start: 1474612
Stop: 1475052
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07033.1|AE004784_6 (AE004784) (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Pseudomonas aeruginosa PAO1]
Identities = 146/146 (100%), Positives = 146/146 (100%)
Sequence:
ATGATGGACATCAACGAGATTCGCGAATACCTGCCTCATCGCTATCCTTTCCTGCTGGTGGATCGGGTGGTA
GAGCTGGACATCGAGGGCAAGCGCATTCGCGCCTACAAGAATGTCAGTATCAATGAGCCGTTCTTCAACGGA
CATTTCCCCGAGCACCCGATCATGCCGGGCGTGCTGATCATCGAGGCGATGGCCCAGGCGGCCGGTATCCTC
GGTTTCAAGATGCTCGACGTGAAGCCCGCCGACGGCACCCTTTACTACTTCGTCGGTTCGGACAAGCTGCGC
TTCCGCCAGCCGGTCCTGCCGGGCGACCAACTGCAACTGCACGCCAAGTTCATCAGCGTGAAGCGCAGCATC
TGGAAATTCGACTGCCACGCTACCGTCGACGACAAGCCGGTATGCTCGGCTGAAATCATCTGTGCGGAACGC
AAACTATGA
Translation:
MMDINEIREYLPHRYPFLLVDRVVELDIEGKRIRAYKNVSINEPFFNGHFPEHPIMPGVLIIEAMAQAAGIL
GFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLQLHAKFISVKRSIWKFDCHATVDDKPVCSAEIICAER
KL*
AnnotationID:4515GeneID:4509
AnnotatorUID: diggins
Modification Date/Time: 2005-04-20 21:09:00
Gene Name:fabZ
Confidence Code:2
GeneProduct:(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(13) Fatty acid and phospholipid metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0764
Secondary Functional Category(ies):
EC Number:4.2.1.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67223.1|AE016349_4 (AE016779) (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase
           [Pseudomonas putida KT2440]
          Length = 163

 Score =  260 bits (665), Expect = 1e-69
 Identities = 126/146 (86%), Positives = 130/146 (89%)

>gb|AAC73291.1| (AE000127) (3R)-hydroxymyristol acyl carrier protein dehydratase
           [Escherichia coli K12]
          Length = 151

 Score =  157 bits (397), Expect = 2e-38
 Identities = 79/144 (54%), Positives = 101/144 (70%), Gaps = 2/144 (1%)








 
Structural Features:
COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases 
[Lipid metabolism]
CD-Length = 147 residues,  95.2% aligned
Score =  183 bits (467), Expect = 1e-47
Identities = 87/143 (60%), Positives = 102/143 (71%), Gaps = 4/143 (2%)








   
Genomic Context:






   
Comment:


















    ReferenceID:9019




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:26161




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31898




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4509_cdd.html


    		




 
URL:

















    ReferenceID:34214




  
Author/Investigator(s):
        Steeghs L, Jennings MP, Poolman JT, van der Ley P.





  
Title:
        Isolation and characterization of the Neisseria meningitidis lpxD-fabZ-lpxA gene cluster involved in lipid A biosynthesis.




  
PubMed:
        9197543


MedLine:
        




    
Source:
Gene. 1997 May 6;190(2):263-70.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9197543









           
Homologs By Global Alignment 

           

       



     
Gene ID:4509
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6864
                           PA3645_tr
                           translation of PA3645
                           146
                           99.99
                           99.99
                           0
                           772.0
     

     
     
183407
                           gb|AAG07033.1|AE004784_6
                           (AE004784) (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Pseudomonas aeruginosa PAO1]
                           146
                           99.99
                           99.99
                           0
                           772.0
     

     
     
183408
                           gb|AAO55065.1|
                           (AE016861) beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Pseudomonas syringae pv. tomato str. DC3000]
                           146
                           86.30
                           90.41
                           0
                           669.0
     

     
     
183409
                           gb|AAN67223.1|AE016349_4
                           (AE016779) (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Pseudomonas putida KT2440]
                           163
                           77.30
                           79.75
                           17
                           665.0
     

     
     
183411
                           gb|AAN54695.1|AE015609_14
                           (AE015609) (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Shewanella oneidensis MR-1]
                           155
                           54.83
                           65.80
                           10
                           424.0
     

     






      

          
GC ORFID: 47511How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3645Glimmer Score: 

          
Start: 3479325Stop: 3478885

          
Length: 441


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3645 translation of PA3645Homolog Bit Score 301.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4630 (ORF: BLASTX 266.0), t_PA3645 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGATGGACATCAACGAGATTCGCGAATACCTGCCTCATCGCTATCCTTTCCTGCTGGTGGATCGGGTGGTA 
GAGCTGGACATCGAGGGCAAGCGCATTCGCGCCTACAAGAATGTCAGTATCAATGAGCCGTTCTTCAACGGA 
CATTTCCCCGAGCACCCGATCATGCCGGGCGTGCTGATCATCGAGGCGATGGCCCAGGCGGCCGGTATCCTC 
GGTTTCAAGATGCTCGACGTGAAGCCCGCCGACGGCACCCTTTACTACTTCGTCGGTTCGGACAAGCTGCGC 
TTCCGCCAGCCGGTCCTGCCGGGCGACCAACTGCAACTGCACGCCAAGTTCATCAGCGTGAAGCGCAGCATC 
TGGAAATTCGACTGCCACGCTACCGTCGACGACAAGCCGGTATGCTCGGCTGAAATCATCTGTGCGGAACGC 
AAACTATGA