ViewGene
Locus Name:
GeneID:
Location:

GeneID:4483
TrivialName: PA14_25540
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_25540
PAO1 Ortholog Locus:PA2978
Sequence Length:465
Protein Length:154
Start: 2231636
Stop: 2232100
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06366.1|AE004723_10 (AE004723) phosphotyrosine protein phosphatase [Pseudomonas aeruginosa PAO1]
Identities = 152/154 (98%), Positives = 152/154 (98%)
Sequence:
ATGCGCGTCCTGTTCGTCTGCCTGGGCAACATCTGCCGGTCGCCCACCGCCGAAGGCGTGTTCCGGCGCAAG
GTCGAGGAGGCCGGGCTGGCCTCCCGTATCCATGTCGATTCCGCCGGCACCGCCGGCTGGCATGTCGGCAAG
GCACCTGACCAGCGCACCCGCCTGGCCGCGCAAAGGCGCGGCTACGATCTGTCGGCACTGCGTGGACGCCAG
GTCGGCATCGAGGATTTCTCCTGCCATGACCTGATCCTGGCCATGGACCTGTCCAACCTGGCCGACCTCGAG
ACCCTGCGTGCCGGGCGCGGTGCCGCCGAGCTGGATCTGTTCCTGCGTCGCTACGGATCCGAGCGGGACGAA
GTACCCGATCCCTACTATGGCGGCGAAGAAGGCTTCGAGCAGGTCCTCGACCTGATCGAACATGCCTGCGAC
CGTCTGTTGATCGAAGTCAAGGGGCGACTGTGA
Translation:
MRVLFVCLGNICRSPTAEGVFRRKVEEAGLASRIHVDSAGTAGWHVGKAPDQRTRLAAQRRGYDLSALRGRQ
VGIEDFSCHDLILAMDLSNLADLETLRAGRGAAELDLFLRRYGSERDEVPDPYYGGEEGFEQVLDLIEHACD
RLLIEVKGRL*
AnnotationID:4489GeneID:4483
AnnotatorUID: diggins
Modification Date/Time: 2005-06-14 05:05:04
Gene Name:ptpA
Confidence Code:2
GeneProduct:phosphotyrosine protein phosphatase
Cell Localization:(1) Cytoplasmic
Synonyms:
Cell Localization Confidence Code:3
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:cd00115,COG0394
Secondary Functional Category(ies):putative enzyme
EC Number:3.1.3.48
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67522.1|AE016380_10 (AE016781) protein-tyrosine-phosphatase [Pseudomonas putida KT2440]
          Length = 154

 Score =  204 bits (520), Expect = 1e-52
 Identities = 101/154 (65%), Positives = 115/154 (74%)

>emb|CAE08541.1| (BX569694) putative low molecular weight
           protein-tyrosine-phosphatase [Synechococcus sp. WH 8102]
          Length = 158

 Score =  152 bits (384), Expect = 6e-37
 Identities = 83/156 (53%), Positives = 103/156 (66%), Gaps = 9/156 (5%)

>emb|CAE32770.1| (BX640443) low molecular weight protein-tyrosine-phosphatase
           [Bordetella bronchiseptica]
          Length = 163

 Score =  151 bits (382), Expect = 1e-36
 Identities = 80/154 (51%), Positives = 105/154 (68%), Gaps = 3/154 (1%)






 
Structural Features:
cd00115, LMWPc, Low molecular weight phosphatase family
CD-Length = 141 residues,  99.3% aligned
Score =  158 bits (400), Expect = 3e-40
Identities = 71/147 (48%), Positives = 85/147 (57%), Gaps = 7/147 (4%)

COG0394, Wzb, Protein-tyrosine-phosphatase [Signal transduction mechanisms]
CD-Length = 139 residues,  95.7% aligned
Score =  137 bits (346), Expect = 7e-34
Identities = 69/147 (46%), Positives = 79/147 (53%), Gaps = 14/147 (9%)







   
Genomic Context:






   
Comment:


















    ReferenceID:8967




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:26109




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36074




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4483_cdd.html


    		




 
URL:

















    ReferenceID:36449




  
Author/Investigator(s):
        Li Y, Strohl WR.





  
Title:
        Cloning, purification, and properties of a phosphotyrosine protein phosphatase from Streptomyces coelicolor A3(2).




  
PubMed:
        8550407


MedLine:
        




    
Source:
J Bacteriol. 1996 Jan;178(1):136-42.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8550407









           
Homologs By Global Alignment 

           

       



     
Gene ID:4483
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6827
                           PA2978_tr
                           translation of PA2978
                           154
                           98.70
                           98.70
                           0
                           781.0
     

     
     
182689
                           gb|AAG06366.1|AE004723_10
                           (AE004723) phosphotyrosine protein phosphatase [Pseudomonas aeruginosa PAO1]
                           154
                           98.70
                           98.70
                           0
                           781.0
     

     
     
182690
                           gb|AAN67522.1|AE016380_10
                           (AE016781) protein-tyrosine-phosphatase [Pseudomonas putida KT2440]
                           154
                           65.58
                           74.67
                           0
                           520.0
     

     
     
182691
                           emb|CAE08541.1|
                           (BX569694) putative low molecular weight protein-tyrosine-phosphatase [Synechococcus sp. WH 8102]
                           161
                           52.79
                           64.59
                           10
                           388.0
     

     
     
182695
                           emb|CAE21863.1|
                           (BX572100) Low molecular weight phosphotyrosine protein phosphatase [Prochlorococcus marinus str. MIT 9313]
                           161
                           50.31
                           65.83
                           9
                           385.0
     

     






      

          
GC ORFID: 47485How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2978Glimmer Score: 

          
Start: 2722289Stop: 2721825

          
Length: 465


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2978 translation of PA2978Homolog Bit Score 305.0

          
Other Homologs:  t_PA2978 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGCGTCCTGTTCGTCTGCCTGGGCAACATCTGCCGGTCGCCCACCGCCGAAGGCGTGTTCCGGCGCAAG 
GTCGAGGAGGCCGGGCTGGCCTCCCGTATCCATGTCGATTCCGCCGGCACCGCCGGCTGGCATGTCGGCAAG 
GCACCTGACCAGCGCACCCGCCTGGCCGCGCAAAGGCGCGGCTACGATCTGTCGGCACTGCGTGGACGCCAG 
GTCGGCATCGAGGATTTCTCCTGCCATGACCTGATCCTGGCCATGGACCTGTCCAACCTGGCCGACCTCGAG 
ACCCTGCGTGCCGGGCGCGGTGCCGCCGAGCTGGATCTGTTCCTGCGTCGCTACGGATCCGAGCGGGACGAA 
GTACCCGATCCCTACTATGGCGGCGAAGAAGGCTTCGAGCAGGTCCTCGACCTGATCGAACATGCCTGCGAC 
CGTCTGTTGATCGAAGTCAAGGGGCGACTGTGA