Modification Date/Time: 2006-04-06 13:01:23
Missense Discrepancy: FALSE
Comments:Homology: gb|AAG07015.1| AE004782_13 (AE004782) 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Pseudomonas aeruginosa PAO1]
Identities = 156/157 (99%), Positives = 156/157 (99%)
Sequence:
ATGCGAATTGGCCATGGCTACGACGTGCATCGCTTCGGCGAGGGCGACTTCATCACCCTCGGCGGCGTGCGC
ATTCCCCACAAACATGGGCTGGTCGCCCACTCCGACGGCGACGTGCTGCTGCACGCCTTGTCCGATGCGCTG
CTCGGCGCGGCGGCGCTGGGCGACATCGGCAAGCACTTCCCGGACACCGACCCGCGGTTCAAGGGCGCCGAC
AGTCGCGCGCTGCTGCGACACGTGGTCGCCATCGTCGCCGAGAAGGGCTGGAAGGTCGGCAACGTCGACGCC
ACCATCGTCGCCCAGGCACCGAAGATGGCGCCGCACATCGAAACCATGCGCGGGTCGATCGCCGAGGACCTC
GGCGTCGCGGTCGACCAGGTCAACGTCAAGGCCACCACTACCGAGCGGCTAGGTTTCACCGGACGCGAAGAG
GGCATTGCTGTACATGCGGTCGCTTTGCTGATGGCCCGATGA
Translation:
MRIGHGYDVHRFGEGDFITLGGVRIPHKHGLVAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPRFKGAD
SRALLRHVVAIVAEKGWKVGNVDATIVAQAPKMAPHIETMRGSIAEDLGVAVDQVNVKATTTERLGFTGREE
GIAVHAVALLMAR*
AnnotationID:4433 GeneID:4427
Modification Date/Time:
2005-06-24 19:07:40
GeneProduct: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cell Localization Confidence Code: 5
Functional Category: (4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code: 5
Secondary Functional Category(ies): fatty acid and phospholipid metabolism
Pathway: Isoprenoid biosynthesis;
Isopentenyl-PP biosynthesis via DXP pathway;
Isopentenyl-PP from 1-deoxy-D-xylulose 5-phosphate: step 4.
Homology: >gb|AAN67239.1| AE016351_1 (AE016780) YgbB/YacN family protein [Pseudomonas putida KT2440]
Length = 157
Score = 281 bits (719), Expect = 9e-76
Identities = 139/155 (89%), Positives = 147/155 (94%)
>gb|AAL21809.1| (AE008833) 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase
[Salmonella typhimurium LT2]
Length = 159
Score = 219 bits (558), Expect = 4e-57
Identities = 112/155 (72%), Positives = 125/155 (80%)
>gb|AAN81762.1| AE016765_164 (AE016765) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
[Escherichia coli CFT073]
Length = 159
Score = 217 bits (552), Expect = 2e-56
Identities = 111/155 (71%), Positives = 124/155 (80%)
Structural Features: COG0245 , IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
[Lipid metabolism]
CD-Length = 159 residues, 97.5% aligned
Score = 240 bits (614), Expect = 1e-64
Identities = 109/155 (70%), Positives = 130/155 (83%)
pfam02542 , YgbB, YgbB family. The ygbB protein is a
putative enzyme of deoxy-xylulose pathway
(terpenoid biosynthesis).
CD-Length = 157 residues, 98.7% aligned
Score = 209 bits (534), Expect = 2e-55
Identities = 95/155 (61%), Positives = 117/155 (75%)