ViewGene
Locus Name:
GeneID:
Location:

GeneID:4397
TrivialName: PA14_35100
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_35100
PAO1 Ortholog Locus:PA2279
Sequence Length:471
Protein Length:156
Start: 3124655
Stop: 3124185
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05667.1|AE004653_10 (AE004653) ArsC protein [Pseudomonas aeruginosa PAO1]
Identities = 156/156 (100%), Positives = 156/156 (100%)
Sequence:
ATGCGAGTCCTGTTCATGTGCACGGCCAACAGTTGCCGCAGCATTCTTTCCGAAGCCATGTTCAACCACCTG
GCCCCGCCGGGTTTCGAGGCATGCAGCGCCGGCAGCCAGCCCAGCGGGCGGGTGCATCCGCGCAGCCTGGCG
ACCCTCGAACAGGCCGGCATCGCCACCCACGGCCTGTACAGCAAGGGCAGCGAAGCCTTCGAAGGCGCACCG
CCGGACATCGTCATCACCGTTTGCGACGCCGCCGCGGGGGAAGCCTGCCCGCTGTATCTCGGCGCAGCGCTG
AAGGCCCATTGGGGCCTGGCCGATCCCTCCGCCCTGGATGGCGACGAAGCCCTGCGGGATGCGGCGTTCCAC
GCCACCCTGGCACGCATCGAACAGCGTTGCAGAGCCTTCCTCGGCCTGCCCTTCGCTACCCTGGATCGCGAC
CAGCTCAAGCGTGAGCTGGAGCGCATCGGCTCGCTCTGA
Translation:
MRVLFMCTANSCRSILSEAMFNHLAPPGFEACSAGSQPSGRVHPRSLATLEQAGIATHGLYSKGSEAFEGAP
PDIVITVCDAAAGEACPLYLGAALKAHWGLADPSALDGDEALRDAAFHATLARIEQRCRAFLGLPFATLDRD
QLKRELERIGSL*
AnnotationID:4403GeneID:4397
AnnotatorUID: diggins
Modification Date/Time: 2005-04-29 07:07:42
Gene Name:arsC
Confidence Code:1
GeneProduct:arsenate reductase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(1) Adaptation, protection
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam01451,COG0394,cd00115
Secondary Functional Category(ies):transport of small molecules
EC Number:1.20.4.1
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN68324.1|AE016466_9 (AE016784) arsenate reductase [Pseudomonas putida KT2440]
          Length = 156

 Score =  241 bits (616), Expect = 8e-64
 Identities = 120/156 (76%), Positives = 132/156 (84%)

>gb|AAF69239.1|AF173880_2 (AF173880) arsenate reductase [Acidithiobacillus ferrooxidans]
          Length = 163

 Score =  154 bits (389), Expect = 2e-37
 Identities = 83/157 (52%), Positives = 102/157 (64%), Gaps = 4/157 (2%)







 
Structural Features:
pfam01451, LMWPc, Low molecular weight phosphotyrosine protein phosphatase. 
CD-Length = 140 residues,  99.3% aligned
Score =  117 bits (294), Expect = 7e-28
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 6/140 (4%)

COG0394, Wzb, Protein-tyrosine-phosphatase [Signal transduction mechanisms]
CD-Length = 139 residues,  95.7% aligned
Score =  114 bits (286), Expect = 5e-27
Identities = 49/139 (35%), Positives = 67/139 (48%), Gaps = 11/139 (7%)

cd00115, LMWPc, Low molecular weight phosphatase family
CD-Length = 141 residues,  99.3% aligned
Score = 96.1 bits (239), Expect = 2e-21
Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 18/146 (12%)






   
Genomic Context:






   
Comment:


















    ReferenceID:8795




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25938




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32502




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4397_cdd.html


    		




 
URL:

















    ReferenceID:34457




  
Author/Investigator(s):
        Cai J, Salmon K, DuBow MS.





  
Title:
        A chromosomal ars operon homologue of Pseudomonas aeruginosa confers increased resistance to arsenic and antimony in Escherichia coli.




  
PubMed:
        9802012


MedLine:
        




    
Source:
Microbiology. 1998 Oct;144 ( Pt 10):2705-13.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9802012

















    ReferenceID:34458




  
Author/Investigator(s):
        Diorio C, Cai J, Marmor J, Shinder R, DuBow MS.





  
Title:
        An Escherichia coli chromosomal ars operon homolog is functional in arsenic detoxification and is conserved in gram-negative bacteria.




  
PubMed:
        7721697


MedLine:
        




    
Source:
J Bacteriol. 1995 Apr;177(8):2050-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7721697









           
Homologs By Global Alignment 

           

       



     
Gene ID:4397
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6733
                           PA2279_tr
                           translation of PA2279
                           156
                           99.99
                           99.99
                           0
                           811.0
     

     
     
180692
                           gb|AAG05667.1|AE004653_10
                           (AE004653) ArsC protein [Pseudomonas aeruginosa PAO1]
                           156
                           99.99
                           99.99
                           0
                           811.0
     

     
     
180693
                           gb|AAC69644.1|
                           (AF010234) ArsC [Pseudomonas aeruginosa]
                           156
                           99.99
                           99.99
                           0
                           811.0
     

     
     
180694
                           gb|AAN68324.1|AE016466_9
                           (AE016784) arsenate reductase [Pseudomonas putida KT2440]
                           156
                           76.92
                           84.61
                           0
                           616.0
     

     
     
180695
                           emb|CAC18654.1|
                           (AJ271973) arsenate reductase [Pseudomonas putida]
                           156
                           69.23
                           78.20
                           0
                           554.0
     

     






      

          
GC ORFID: 47399How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2279Glimmer Score: 

          
Start: 1829261Stop: 1829731

          
Length: 471


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2279 translation of PA2279Homolog Bit Score 317.0

          
Other Homologs:  psyr_15may02_Scaffold10_revised_gene1596 (ORF: BLASTX 186.0), t_PA2279 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGAGTCCTGTTCATGTGCACGGCCAACAGTTGCCGCAGCATTCTTTCCGAAGCCATGTTCAACCACCTG 
GCCCCGCCGGGTTTCGAGGCATGCAGCGCCGGCAGCCAGCCCAGCGGGCGGGTGCATCCGCGCAGCCTGGCG 
ACCCTCGAACAGGCCGGCATCGCCACCCACGGCCTGTACAGCAAGGGCAGCGAAGCCTTCGAAGGCGCACCG 
CCGGACATCGTCATCACCGTTTGCGACGCCGCCGCGGGGGAAGCCTGCCCGCTGTATCTCGGCGCAGCGCTG 
AAGGCCCATTGGGGCCTGGCCGATCCCTCCGCCCTGGATGGCGACGAAGCCCTGCGGGATGCGGCGTTCCAC 
GCCACCCTGGCACGCATCGAACAGCGTTGCAGAGCCTTCCTCGGCCTGCCCTTCGCTACCCTGGATCGCGAC 
CAGCTCAAGCGTGAGCTGGAGCGCATCGGCTCGCTCTGA