ViewGene
Locus Name:
GeneID:
Location:

GeneID:4383
TrivialName: PA14_71620
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_71620
PAO1 Ortholog Locus:PA5426
Sequence Length:492
Protein Length:163
Start: 6379686
Stop: 6379195
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08811.1|AE004955_5 (AE004955) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Pseudomonas aeruginosa PAO1]
Identities = 163/163 (100%), Positives = 163/163 (100%)
Sequence:
ATGAGCGCACTGGTTGGCGTGATCATGGGTTCCAAATCGGACTGGAGCACCCTCAGTCACACCGCGGACATG
CTGGACAAGCTGGGCATCCCCTACGAAGTGAAGGTGGTTTCCGCCCACCGCACCCCGGACCTGCTCTTCCAG
TACGCCGAGGAAGCCGAAGGCCGCGGCCTCGAAGTGATCATCGCCGGCGCTGGCGGCGCCGCCCACCTGCCG
GGCATGTGCGCGGCCAAGACCCACCTGCCGGTACTCGGCGTGCCGGTACAGTCGTCGATGCTGTCGGGTGTC
GACTCGCTGCTCTCCATCGTGCAGATGCCCGCCGGCGTACCGGTCGCCACCCTGGCCATCGGCAAGGCCGGC
GCGGTCAACGCGGCGCTGCTCTCGGCGAGCATCCTCGGCGCCAAGCACCCGCAGTACCACGAGGCGCTGAAG
CAGTTCCGCGCCAACCAGACCGAAACCGTGCTGGACAATCCCGACCCGCGCGATGCGTGA
Translation:
MSALVGVIMGSKSDWSTLSHTADMLDKLGIPYEVKVVSAHRTPDLLFQYAEEAEGRGLEVIIAGAGGAAHLP
GMCAAKTHLPVLGVPVQSSMLSGVDSLLSIVQMPAGVPVATLAIGKAGAVNAALLSASILGAKHPQYHEALK
QFRANQTETVLDNPDPRDA*
AnnotationID:4389GeneID:4383
AnnotatorUID: diggins
Modification Date/Time: 2005-03-17 14:02:47
Gene Name:purE
Confidence Code:1
GeneProduct:phosphoribosylaminoimidazole carboxylase, catalytic subunit
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0041,pfam00731
Secondary Functional Category(ies):
EC Number:4.1.1.21
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70901.1|AE016734_5 (AE016794) phosphoribosylaminoimidazole carboxylase, catalytic
           subunit [Pseudomonas putida KT2440]
          Length = 163

 Score =  305 bits (780), Expect = 9e-83
 Identities = 154/163 (94%), Positives = 159/163 (97%)

>gb|AAO58913.1| (AE016876) phosphoribosylaminoimidazole carboxylase, catalytic
           subunit [Pseudomonas syringae pv. tomato str. DC3000]
          Length = 168

 Score =  300 bits (767), Expect = 3e-81
 Identities = 149/163 (91%), Positives = 159/163 (97%)

>gb|AAM41777.1| (AE012362) phosphoribosylaminoimidazole carboxylase catalytic
           subunit [Xanthomonas campestris pv. campestris str. ATCC
           33913]
          Length = 167

 Score =  223 bits (568), Expect = 3e-58
 Identities = 110/158 (69%), Positives = 129/158 (81%)








 
Structural Features:
COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase 
[Nucleotide transport and metabolism]
CD-Length = 162 residues,  98.1% aligned
Score =  235 bits (601), Expect = 2e-63
Identities = 107/161 (66%), Positives = 129/161 (80%), Gaps = 2/161 (1%)

pfam00731, AIRC, AIR carboxylase. 
CD-Length = 157 residues, 100.0% aligned
Score =  204 bits (520), Expect = 5e-54
Identities = 101/159 (63%), Positives = 121/159 (76%), Gaps = 2/159 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:8767




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25910




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34683




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4383_cdd.html


    		




 
URL:

















    ReferenceID:35637




  
Author/Investigator(s):
        Wang J, Mushegian A, Lory S, Jin S.





  
Title:
        Large-scale isolation of candidate virulence genes of Pseudomonas aeruginosa by in vivo selection.




  
PubMed:
        8816818


MedLine:
        




    
Source:
Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10434-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8816818









           
Homologs By Global Alignment 

           

       



     
Gene ID:4383
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6719
                           PA5426_tr
                           translation of PA5426
                           163
                           99.99
                           99.99
                           0
                           820.0
     

     
     
180505
                           gb|AAG08811.1|AE004955_5
                           (AE004955) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Pseudomonas aeruginosa PAO1]
                           163
                           99.99
                           99.99
                           0
                           820.0
     

     
     
180506
                           gb|AAB17257.1|
                           (U58364) PurE [Pseudomonas aeruginosa]
                           163
                           98.77
                           98.77
                           0
                           811.0
     

     
     
180507
                           gb|AAN70901.1|AE016734_5
                           (AE016794) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Pseudomonas putida KT2440]
                           163
                           94.47
                           97.54
                           0
                           780.0
     

     
     
180508
                           gb|AAO58913.1|
                           (AE016876) phosphoribosylaminoimidazole carboxylase, catalytic subunit [Pseudomonas syringae pv. tomato str. DC3000]
                           168
                           88.69
                           94.64
                           5
                           767.0
     

     






      

          
GC ORFID: 47385How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA5426Glimmer Score: 

          
Start: 5643375Stop: 5642884

          
Length: 492


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA5426 translation of PA5426Homolog Bit Score 320.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene4187 (ORF: BLASTX 300.0), t_PA5426 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAGCGCACTGGTTGGCGTGATCATGGGTTCCAAATCGGACTGGAGCACCCTCAGTCACACCGCGGACATG 
CTGGACAAGCTGGGCATCCCCTACGAAGTGAAGGTGGTTTCCGCCCACCGCACCCCGGACCTGCTCTTCCAG 
TACGCCGAGGAAGCCGAAGGCCGCGGCCTCGAAGTGATCATCGCCGGCGCTGGCGGCGCCGCCCACCTGCCG 
GGCATGTGCGCGGCCAAGACCCACCTGCCGGTACTCGGCGTGCCGGTACAGTCGTCGATGCTGTCGGGTGTC 
GACTCGCTGCTCTCCATCGTGCAGATGCCCGCCGGCGTACCGGTCGCCACCCTGGCCATCGGCAAGGCCGGC 
GCGGTCAACGCGGCGCTGCTCTCGGCGAGCATCCTCGGCGCCAAGCACCCGCAGTACCACGAGGCGCTGAAG 
CAGTTCCGCGCCAACCAGACCGAAACCGTGCTGGACAATCCCGACCCGCGCGATGCGTGA