ViewGene
Locus Name:
GeneID:
Location:

GeneID:4367
TrivialName: PA14_31810
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_31810
PAO1 Ortholog Locus:PA2532
Sequence Length:498
Protein Length:165
Start: 2767072
Stop: 2767569
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05920.1|AE004681_2 (AE004681) thiol peroxidase [Pseudomonas aeruginosa PAO1]
Identities = 165/165 (100%), Positives = 165/165 (100%)
Sequence:
ATGGCTCAAGTGACTCTCAAGGGCAACCCGGTCAACGTCGATGGCCAGCTCCCGCAGAAAGGCGCCCAGGCT
CCGGCCTTCAGCCTGGTCGGCGGCGACCTCGCCGACGTGACCCTGGAAAACTTCGCCGGCAAGCGCAAGGTG
CTGAACATCTTCCCCAGCGTCGACACCCCGACCTGCGCCACCTCGGTGCGCAAGTTCAACGTCGAGGCCGGC
AAGCTGGCCAATACCGTGGTGCTGTGCATTTCCGCCGACCTGCCGTTCGCGCAGAAGCGCTTCTGCGGCGCC
GAAGGTTTGGAGAACGTAGTCAACCTGTCGACCCTGCGCGGTCGCGAGTTCCTCGAGAACTATGGCGTGGCC
ATCGCCAGCGGCCCGCTGGCCGGCCTGGCCGCGCGCGCCGTGGTGGTGCTCGACGAGCAGAACAAGGTGCTG
CACAGCGAACTGGTCGGCGAAATCGCCGACGAGCCGAACTACGCGGCGGCCCTGGCGGCTCTCTGA
Translation:
MAQVTLKGNPVNVDGQLPQKGAQAPAFSLVGGDLADVTLENFAGKRKVLNIFPSVDTPTCATSVRKFNVEAG
KLANTVVLCISADLPFAQKRFCGAEGLENVVNLSTLRGREFLENYGVAIASGPLAGLAARAVVVLDEQNKVL
HSELVGEIADEPNYAAALAAL*
AnnotationID:4373GeneID:4367
AnnotatorUID: diggins
Modification Date/Time: 2005-04-29 10:10:06
Gene Name:tpx
Confidence Code:2
GeneProduct:thiol peroxidase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(1) Adaptation, protection
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG2077
Secondary Functional Category(ies):posttranslational modification, protein turnover, chaperones
EC Number:1.11.1.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN69187.1|AE016553_2 (AE016787) thiol peroxidase [Pseudomonas putida KT2440]
          Length = 166

 Score =  276 bits (706), Expect = 3e-74
 Identities = 141/165 (85%), Positives = 150/165 (90%)

>gb|AAO56253.1| (AE016865) thiol peroxidase [Pseudomonas syringae pv. tomato str.
           DC3000]
          Length = 166

 Score =  241 bits (616), Expect = 9e-64
 Identities = 124/165 (75%), Positives = 138/165 (83%)

>gb|AAM85556.1|AE013802_1 (AE013802) thiol peroxidase [Yersinia pestis KIM]
          Length = 191

 Score =  221 bits (563), Expect = 1e-57
 Identities = 114/162 (70%), Positives = 130/162 (80%)






 
Structural Features:
COG2077, Tpx, Peroxiredoxin 
[Posttranslational modification, protein turnover, chaperones]
CD-Length = 158 residues, 100.0% aligned
Score =  243 bits (623), Expect = 6e-66
Identities = 109/158 (68%), Positives = 123/158 (77%)








   
Genomic Context:






   
Comment:


















    ReferenceID:8735




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25878




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33093




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4367_cdd.html


    		




 
URL:

















    ReferenceID:34527




  
Author/Investigator(s):
        Chae HZ, Chung SJ, Rhee SG.





  
Title:
        Thioredoxin-dependent peroxide reductase from yeast.




  
PubMed:
        7961686


MedLine:
        




    
Source:
J Biol Chem. 1994 Nov 4;269(44):27670-8.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7961686

















    ReferenceID:34528




  
Author/Investigator(s):
        Kim HK, Kim SJ, Lee JW, Lee JW, Cha MK, Kim IH.





  
Title:
        Identification of promoter in the 5'-flanking region of the E. coli thioredoxin-linked thiol peroxidase gene: evidence for the existence of oxygen-related transcriptional regulatory protein.




  
PubMed:
        8630014


MedLine:
        




    
Source:
Biochem Biophys Res Commun. 1996 Apr 25;221(3):641-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8630014

















    ReferenceID:34529




  
Author/Investigator(s):
        Klimowski L, Chandrashekar R, Tripp CA.





  
Title:
        Molecular cloning, expression and enzymatic activity of a thioredoxin peroxidase from Dirofilaria immitis.




  
PubMed:
        9497051


MedLine:
        




    
Source:
Mol Biochem Parasitol. 1997 Dec 1;90(1):297-306.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9497051









           
Homologs By Global Alignment 

           

       



     
Gene ID:4367
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6703
                           PA2532_tr
                           translation of PA2532
                           165
                           99.99
                           99.99
                           0
                           825.0
     

     
     
180077
                           gb|AAG05920.1|AE004681_2
                           (AE004681) thiol peroxidase [Pseudomonas aeruginosa PAO1]
                           165
                           99.99
                           99.99
                           0
                           825.0
     

     
     
180078
                           gb|AAN69187.1|AE016553_2
                           (AE016787) thiol peroxidase [Pseudomonas putida KT2440]
                           166
                           84.93
                           90.36
                           1
                           706.0
     

     
     
180079
                           gb|AAQ58545.1|
                           (AE016912) thiol peroxidase [Chromobacterium violaceum ATCC 12472]
                           165
                           76.36
                           86.06
                           0
                           639.0
     

     
     
180080
                           gb|AAO56253.1|
                           (AE016865) thiol peroxidase [Pseudomonas syringae pv. tomato str. DC3000]
                           166
                           74.69
                           83.13
                           1
                           616.0
     

     






      

          
GC ORFID: 47369How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2532Glimmer Score: 

          
Start: 2186854Stop: 2186357

          
Length: 498


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2532 translation of PA2532Homolog Bit Score 322.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene1336 (ORF: BLASTX 242.0), t_PA2532 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGGCTCAAGTGACTCTCAAGGGCAACCCGGTCAACGTCGATGGCCAGCTCCCGCAGAAAGGCGCCCAGGCT 
CCGGCCTTCAGCCTGGTCGGCGGCGACCTCGCCGACGTGACCCTGGAAAACTTCGCCGGCAAGCGCAAGGTG 
CTGAACATCTTCCCCAGCGTCGACACCCCGACCTGCGCCACCTCGGTGCGCAAGTTCAACGTCGAGGCCGGC 
AAGCTGGCCAATACCGTGGTGCTGTGCATTTCCGCCGACCTGCCGTTCGCGCAGAAGCGCTTCTGCGGCGCC 
GAAGGTTTGGAGAACGTAGTCAACCTGTCGACCCTGCGCGGTCGCGAGTTCCTCGAGAACTATGGCGTGGCC 
ATCGCCAGCGGCCCGCTGGCCGGCCTGGCCGCGCGCGCCGTGGTGGTGCTCGACGAGCAGAACAAGGTGCTG 
CACAGCGAACTGGTCGGCGAAATCGCCGACGAGCCGAACTACGCGGCGGCCCTGGCGGCTCTCTGA