ViewGene
Locus Name:
GeneID:
Location:

GeneID:431
TrivialName: PA14_11550
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_11550
PAO1 Ortholog Locus:PA4044
Sequence Length:1884
Protein Length:627
Start: 999702
Stop: 997819
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07431.1|AE004821_4 (AE004821) 1-deoxyxylulose-5-phosphate synthase [Pseudomonas aeruginosa PAO1]
Identities = 627/627 (100%), Positives = 627/627 (100%)
Sequence:
ATGCCCAAGACGCTCCATGAGATTCCCCGCGAGCGCCCCGCCACGCCCCTGCTCGACCGCGCCTCTTCGCCG
GCCGAACTGCGCCGGCTGGGCGAGGCGGACCTGGAAACCCTGGCCGACGAGCTGCGCCAGTACCTGCTGTAT
ACCGTCGGGCAGACCGGCGGTCATTTCGGCGCCGGCCTCGGCGTGGTCGAGCTGACCATCGCCCTGCACTAC
GTCTTCGACACTCCGGACGATCGCCTGGTCTGGGACGTCGGCCACCAGGCCTATCCGCACAAGATCCTCACC
GAACGCCGCGAGCTGATGGGCACCCTGCGCCAGAAGAACGGCCTGGCGGCCTTCCCGCGCCGCGCAGAGAGC
GAGTACGACACCTTCGGCGTCGGCCACTCCAGCACCTCCATCAGCGCCGCCCTGGGCATGGCCATCGCCGCC
CGCCTGCAAGGCAAGGAGCGTAAGTCGGTGGCCGTGATCGGCGACGGTGCGCTGACCGCCGGCATGGCCTTC
GAGGCACTCAACCACGCCTCGGAAGTCGACGCCGACATGCTGGTGATCCTCAACGACAACGACATGTCGATC
TCGCACAACGTCGGCGGGCTCTCCAACTACCTGGCGAAGATCCTCTCCAGCCGCACCTATAGCAGCATGCGC
GAGGGCAGCAAGAAGGTGCTCTCGCGCCTGCCCGGGGCCTGGGAGATCGCCCGGCGCACCGAGGAATACGCC
AAGGGCATGCTGGTCCCCGGCACCCTGTTCGAGGAGCTCGGCTGGAACTACATCGGCCCGATCGACGGCCAC
GACCTGCCGACCCTGGTGGCTACCCTGCGCAACATGCGCGACATGAAGGGCCCGCAGTTCCTCCATGTGGTG
ACCAAGAAAGGCAAGGGCTTCGCCCCGGCCGAACTGGATCCGATCGGCTACCACGCGATCACCAAGCTGGAA
GCTCCCGGCAGTGCGCCGAAGAAGACCGGCGGACCCAAGTATTCCAGCGTCTTCGGCCAGTGGCTGTGCGAC
ATGGCCGCCCAGGACGCGCGCCTGCTCGGCATCACCCCGGCGATGAAGGAAGGTTCCGACCTGGTGGCCTTC
AGCGAACGCTACCCGGAACGCTACTTCGACGTCGCCATCGCCGAACAGCATGCCGTGACCCTGGCCGCCGGC
ATGGCCTGCGAGGGCATGAAGCCGGTGGTGGCGATCTACTCGACCTTCCTCCAGCGCGCCTACGACCAGTTG
ATCCATGACGTCGCCGTGCAGCACCTCGACGTGCTGTTCGCCATCGACCGCGCCGGCCTGGTCGGCGAGGAC
GGCCCGACCCACGCCGGTAGCTTCGACATCTCCTACCTGCGCTGCATCCCCGGCATGCTGGTGATGACCCCC
AGCGACGAGGACGAGCTGCGCAAGCTGCTCACCACCGGCTACCTGTTCGATGGCCCGGCCGCGGTGCGCTAT
CCGCGCGGCAGCGGCCCCAACCATCCGATCGATCCGGACCTGCAACCGGTGGAGATCGGCAAGGGCGTGGTC
CGTCGGCGCGGCGGCAGGGTCGCACTGCTGGTCTTCGGCGTGCAGTTGGCGGAGGCGATGAAGGTTGCCGAA
AGCCTCGACGCCACAGTCGTCGACATGCGTTTCGTCAAACCCCTCGACGAAGCCCTGGTACGCGAATTGGCG
GGCAGCCACGAACTGCTGGTGACCATCGAGGAAAACGCCGTGATGGGCGGCGCCGGCTCGGCGGTCGGCGAG
TTCCTCGCCAGCGAGGGCCTCGAAGTCCCGCTGCTGCAACTGGGCCTGCCCGACTACTACGTCGAACACGCC
AAGCCCAGCGAGATGCTCGCCGAATGCGGCCTGGATGCCGCGGGCATcGAAAAGGCGGTACGCCAGCGTCTC
gaccGGCAGTAG
Translation:
MPKTLHEIPRERPATPLLDRASSPAELRRLGEADLETLADELRQYLLYTVGQTGGHFGAGLGVVELTIALHY
VFDTPDDRLVWDVGHQAYPHKILTERRELMGTLRQKNGLAAFPRRAESEYDTFGVGHSSTSISAALGMAIAA
RLQGKERKSVAVIGDGALTAGMAFEALNHASEVDADMLVILNDNDMSISHNVGGLSNYLAKILSSRTYSSMR
EGSKKVLSRLPGAWEIARRTEEYAKGMLVPGTLFEELGWNYIGPIDGHDLPTLVATLRNMRDMKGPQFLHVV
TKKGKGFAPAELDPIGYHAITKLEAPGSAPKKTGGPKYSSVFGQWLCDMAAQDARLLGITPAMKEGSDLVAF
SERYPERYFDVAIAEQHAVTLAAGMACEGMKPVVAIYSTFLQRAYDQLIHDVAVQHLDVLFAIDRAGLVGED
GPTHAGSFDISYLRCIPGMLVMTPSDEDELRKLLTTGYLFDGPAAVRYPRGSGPNHPIDPDLQPVEIGKGVV
RRRGGRVALLVFGVQLAEAMKVAESLDATVVDMRFVKPLDEALVRELAGSHELLVTIEENAVMGGAGSAVGE
FLASEGLEVPLLQLGLPDYYVEHAKPSEMLAECGLDAAGIEKAVRQRLDRQ*
AnnotationID:440GeneID:431
AnnotatorUID: urbach
Modification Date/Time: 2004-10-05 19:07:26
Gene Name:dxs
Confidence Code:2
GeneProduct:1-deoxyxylulose-5-phosphate synthase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:dxp synthase
Functional Category Confidence Code:5
COGs:COG1154,KOG0523,COG3958
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
gb|AAC46162.1| (AF035440) D-1-deoxyxylulose 5-phosphate synthase [Escherichia coli]
Length: 630
PctIdentity: 61.11
PctSimilarity: 77.46
Gaps: 13
BitScore: 2025.0






 
Structural Features:
gnl|CDD|10873 COG1154, Dxs, Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism/ Lipid metabolism]
Length = 627
Score =  940 bits (2432), Expect = 0.0
Identities = 384/625 (61%), Positives = 483/625 (77%), Gaps = 11/625 (1%)






   
Genomic Context:






   
Comment:


















    ReferenceID:865




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:18007




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34629




  
Author/Investigator(s):
        Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, Boronat A.





  
Title:
        Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.




  
PubMed:
        9482846


MedLine:
        




    
Source:
Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2105-10.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=98151473&dopt=Citation









           
Homologs By Global Alignment 

           

       



     
Gene ID:431
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
723
                           PA4044_tr
                           translation of PA4044
                           627
                           99.99
                           99.99
                           0
                           3219.0
     

     
     
32409
                           gb|AAG07431.1|AE004821_4
                           (AE004821) 1-deoxyxylulose-5-phosphate synthase [Pseudomonas aeruginosa PAO1]
                           627
                           99.99
                           99.99
                           0
                           3219.0
     

     
     
32410
                           gb|AAF97240.1|AF282878_1
                           (AF282878) 1-deoxy-D-xylulose 5-phosphate synthase; Dxp [Pseudomonas aeruginosa]
                           627
                           99.99
                           99.99
                           0
                           3219.0
     

     
     
32412
                           gb|AAO54240.1|
                           (AE016858) deoxyxylulose-5-phosphate synthase [Pseudomonas syringae pv. tomato str. DC3000]
                           631
                           83.99
                           90.49
                           4
                           2726.0
     

     
     
32411
                           gb|AAN66154.1|AE016243_6
                           (AE016776) deoxyxylulose-5-phosphate synthase [Pseudomonas putida KT2440]
                           655
                           83.20
                           89.46
                           28
                           2816.0
     

     






      

          
GC ORFID: 43433How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4044Glimmer Score: 

          
Start: 3954235Stop: 3956118

          
Length: 1884


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA4044 translation of PA4044Homolog Bit Score 1244.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene3641 (ORF: BLASTX 1055.0), t_PA4044 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCCCAAGACGCTCCATGAGATTCCCCGCGAGCGCCCCGCCACGCCCCTGCTCGACCGCGCCTCTTCGCCG 
GCCGAACTGCGCCGGCTGGGCGAGGCGGACCTGGAAACCCTGGCCGACGAGCTGCGCCAGTACCTGCTGTAT 
ACCGTCGGGCAGACCGGCGGTCATTTCGGCGCCGGCCTCGGCGTGGTCGAGCTGACCATCGCCCTGCACTAC 
GTCTTCGACACTCCGGACGATCGCCTGGTCTGGGACGTCGGCCACCAGGCCTATCCGCACAAGATCCTCACC 
GAACGCCGCGAGCTGATGGGCACCCTGCGCCAGAAGAACGGCCTGGCGGCCTTCCCGCGCCGCGCAGAGAGC 
GAGTACGACACCTTCGGCGTCGGCCACTCCAGCACCTCCATCAGCGCCGCCCTGGGCATGGCCATCGCCGCC 
CGCCTGCAAGGCAAGGAGCGTAAGTCGGTGGCCGTGATCGGCGACGGTGCGCTGACCGCCGGCATGGCCTTC 
GAGGCACTCAACCACGCCTCGGAAGTCGACGCCGACATGCTGGTGATCCTCAACGACAACGACATGTCGATC 
TCGCACAACGTCGGCGGGCTCTCCAACTACCTGGCGAAGATCCTCTCCAGCCGCACCTATAGCAGCATGCGC 
GAGGGCAGCAAGAAGGTGCTCTCGCGCCTGCCCGGGGCCTGGGAGATCGCCCGGCGCACCGAGGAATACGCC 
AAGGGCATGCTGGTCCCCGGCACCCTGTTCGAGGAGCTCGGCTGGAACTACATCGGCCCGATCGACGGCCAC 
GACCTGCCGACCCTGGTGGCTACCCTGCGCAACATGCGCGACATGAAGGGCCCGCAGTTCCTCCATGTGGTG 
ACCAAGAAAGGCAAGGGCTTCGCCCCGGCCGAACTGGATCCGATCGGCTACCACGCGATCACCAAGCTGGAA 
GCTCCCGGCAGTGCGCCGAAGAAGACCGGCGGACCCAAGTATTCCAGCGTCTTCGGCCAGTGGCTGTGCGAC 
ATGGCCGCCCAGGACGCGCGCCTGCTCGGCATCACCCCGGCGATGAAGGAAGGTTCCGACCTGGTGGCCTTC 
AGCGAACGCTACCCGGAACGCTACTTCGACGTCGCCATCGCCGAACAGCATGCCGTGACCCTGGCCGCCGGC 
ATGGCCTGCGAGGGCATGAAGCCGGTGGTGGCGATCTACTCGACCTTCCTCCAGCGCGCCTACGACCAGTTG 
ATCCATGACGTCGCCGTGCAGCACCTCGACGTGCTGTTCGCCATCGACCGCGCCGGCCTGGTCGGCGAGGAC 
GGCCCGACCCACGCCGGTAGCTTCGACATCTCCTACCTGCGCTGCATCCCCGGCATGCTGGTGATGACCCCC 
AGCGACGAGGACGAGCTGCGCAAGCTGCTCACCACCGGCTACCTGTTCGATGGCCCGGCCGCGGTGCGCTAT 
CCGCGCGGCAGCGGCCCCAACCATCCGATCGATCCGGACCTGCAACCGGTGGAGATCGGCAAGGGCGTGGTC 
CGTCGGCGCGGCGGCAGGGTCGCACTGCTGGTCTTCGGCGTGCAGTTGGCGGAGGCGATGAAGGTTGCCGAA 
AGCCTCGACGCCACAGTCGTCGACATGCGTTTCGTCAAACCCCTCGACGAAGCCCTGGTACGCGAATTGGCG 
GGCAGCCACGAACTGCTGGTGACCATCGAGGAAAACGCCGTGATGGGCGGCGCCGGCTCGGCGGTCGGCGAG 
TTCCTCGCCAGCGAGGGCCTCGAAGTCCCGCTGCTGCAACTGGGCCTGCCCGACTACTACGTCGAACACGCC 
AAGCCCAGCGAGATGCTCGCCGAATGCGGCCTGGATGCCGCGGGCATcGAAAAGGCGGTACGCCAGCGTCTC 
gaccGGCAGTAG