ViewGene
Locus Name:
GeneID:
Location:

GeneID:4264
TrivialName: PA14_41390
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_41390
PAO1 Ortholog Locus:PA1793
Sequence Length:498
Protein Length:165
Start: 3691732
Stop: 3692229
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05182.1|AE004605_4 (AE004605) peptidyl-prolyl cis-trans isomerase B [Pseudomonas aeruginosa PAO1]
Identities = 165/165 (100%), Positives = 165/165 (100%)
Sequence:
ATGATCAAGCTGCATACCAACCATGGCGTCATCACCCTGAAGCTCGATGAAGAGAAAGCCCCGGAAACCGCG
GCGAACTTCAAGGAGTACGTGAAAAGTGGCCACTACGACAACACCGTCTTCCACCGCGTGATCAACAACTTC
ATGATCCAGGGTGGCGGTTTCGAGCCGGGCATGAAGCAGAAGCCCACTCGCGCACCGATCAAGAACGAAGCC
AACAACGGCCTGACCAACAAGGTCGGCAGCATCGCCATGGCCCGTACCATGGACCCGCATTCGGCCAGCGCG
CAGTTCTTCATCAACGTCGCCGACAACGACTTCCTCAACCACACCGCCCCCACCACCCAGGGCTGGGGCTAT
GCCGTCTTCGGCGAAGTGGTCGAGGGCATGGACGTGGTCAACAAGATCAAGGGCGTGGCCACCACCATGCGC
AGCGGCCACCAGGACGTGCCGGCCGAGGACGTGATCATCGAGAAGGCCGAAATCGTCGAAGAATGA
Translation:
MIKLHTNHGVITLKLDEEKAPETAANFKEYVKSGHYDNTVFHRVINNFMIQGGGFEPGMKQKPTRAPIKNEA
NNGLTNKVGSIAMARTMDPHSASAQFFINVADNDFLNHTAPTTQGWGYAVFGEVVEGMDVVNKIKGVATTMR
SGHQDVPAEDVIIEKAEIVEE*
AnnotationID:4270GeneID:4264
AnnotatorUID: diggins
Modification Date/Time: 2005-06-02 07:07:17
Gene Name:ppiB
Confidence Code:2
GeneProduct:peptidyl-prolyl cis-trans isomerase B
Cell Localization:(1) Cytoplasmic
Synonyms:
Cell Localization Confidence Code:2
MolecularFunction:
Functional Category:(26) Translation, post-translational modification, degradation
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0652
Secondary Functional Category(ies):chaperones & heat shock proteins
EC Number:5.2.1.8
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAD14866.1| (AL646063) PROBABLE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B (PPIASE
           B) (ROTAMASE B)(CYPB PROTEIN) [Ralstonia solanacearum]
          Length = 179

 Score =  253 bits (647), Expect = 2e-67
 Identities = 123/165 (74%), Positives = 137/165 (83%), Gaps = 2/165 (1%)

>gb|AAO57213.1| (AE016869) peptidyl-prolyl cis-trans isomerase B [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 167

 Score =  250 bits (638), Expect = 3e-66
 Identities = 122/164 (74%), Positives = 140/164 (85%), Gaps = 1/164 (0%)

>gb|AAN68511.1|AE016483_2 (AE016784) peptidyl-prolyl cis-trans isomerase B [Pseudomonas
           putida KT2440]
          Length = 166

 Score =  239 bits (610), Expect = 5e-63
 Identities = 116/163 (71%), Positives = 133/163 (81%)








 
Structural Features:
COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family 
[Posttranslational modification, protein turnover, chaperones]
CD-Length = 158 residues, 100.0% aligned
Score =  193 bits (493), Expect = 7e-51
Identities = 81/166 (48%), Positives = 100/166 (60%), Gaps = 10/166 (6%)






   
Genomic Context:






   
Comment:


















    ReferenceID:8529




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25671




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37132




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:4264_cdd.html


    		




 
URL:

















    ReferenceID:37809




  
Author/Investigator(s):
        Herrler M, Bang H, Marahiel MA.





  
Title:
        Cloning and characterization of ppiB, a Bacillus subtilis gene which encodes a cyclosporin A-sensitive peptidyl-prolyl cis-trans isomerase.




  
PubMed:
        8022278


MedLine:
        




    
Source:
Mol Microbiol. 1994 Mar;11(6):1073-83.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8022278









           
Homologs By Global Alignment 

           

       



     
Gene ID:4264
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6560
                           PA1793_tr
                           translation of PA1793
                           165
                           99.99
                           99.99
                           0
                           864.0
     

     
     
177717
                           gb|AAG05182.1|AE004605_4
                           (AE004605) peptidyl-prolyl cis-trans isomerase B [Pseudomonas aeruginosa PAO1]
                           165
                           99.99
                           99.99
                           0
                           864.0
     

     
     
177719
                           gb|AAO57213.1|
                           (AE016869) peptidyl-prolyl cis-trans isomerase B [Pseudomonas syringae pv. tomato str. DC3000]
                           168
                           72.61
                           83.33
                           4
                           639.0
     

     
     
177720
                           gb|AAQ60851.1|
                           (AE016921) probable peptidyl-prolyl cis-trans isomerase [Chromobacterium violaceum ATCC 12472]
                           165
                           70.30
                           83.03
                           2
                           618.0
     

     
     
177725
                           dbj|BAC94125.1|
                           (AP005335) peptidyl-prolyl cis-trans isomerase B [Vibrio vulnificus YJ016]
                           165
                           69.69
                           81.21
                           1
                           600.0
     

     






      

          
GC ORFID: 47266How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1793Glimmer Score: 

          
Start: 1262177Stop: 1261680

          
Length: 498


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA1793 translation of PA1793Homolog Bit Score 337.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene653 (ORF: BLASTX 258.0), t_PA3227 (ORF: BLASTX 177.0), psyr_15may02_Scaffold5_revised_gene6053 (ORF: BLASTX 166.0), t_PA1793 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGATCAAGCTGCATACCAACCATGGCGTCATCACCCTGAAGCTCGATGAAGAGAAAGCCCCGGAAACCGCG 
GCGAACTTCAAGGAGTACGTGAAAAGTGGCCACTACGACAACACCGTCTTCCACCGCGTGATCAACAACTTC 
ATGATCCAGGGTGGCGGTTTCGAGCCGGGCATGAAGCAGAAGCCCACTCGCGCACCGATCAAGAACGAAGCC 
AACAACGGCCTGACCAACAAGGTCGGCAGCATCGCCATGGCCCGTACCATGGACCCGCATTCGGCCAGCGCG 
CAGTTCTTCATCAACGTCGCCGACAACGACTTCCTCAACCACACCGCCCCCACCACCCAGGGCTGGGGCTAT 
GCCGTCTTCGGCGAAGTGGTCGAGGGCATGGACGTGGTCAACAAGATCAAGGGCGTGGCCACCACCATGCGC 
AGCGGCCACCAGGACGTGCCGGCCGAGGACGTGATCATCGAGAAGGCCGAAATCGTCGAAGAATGA