ViewGene
Locus Name:
GeneID:
Location:

GeneID:417
TrivialName: PA14_23970
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23970
PAO1 Ortholog Locus:PA3105
Sequence Length:1977
Protein Length:658
Start: 2083936
Stop: 2081960
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06493.1|AE004734_11 (AE004734) general secretion pathway protein D [Pseudomonas aeruginosa PAO1]
Identities = 656/658 (99%), Positives = 656/658 (99%)
Sequence:
ATGTCCCAACCTTTGCTCCGCGCCCTGTTTGCCCCTTCCAGTCGTTCGTACGTTCCCGCCGTCCTTCTCAGC
CTGGCCCTCGGCATCCAGGCGGCGCACGCCGAAAACAGCGGCGGGAACGCCTTCGTCCCGGCCGGCAACCAG
CAGGAGGCGCACTGGACGATCAACCTCAAGGATGCCGACATCCGCGAATTCATCGACCAGATTTCCGAAATC
ACCGGCGAGACCTTCGTCGTCGACCCGCGGGTCAAGGGCCAGGTCAGCGTGGTCTCCAAGGCCCAGCTCTCG
TTGAGCGAGGTCTACCAGTTGTTCCTCTCGGTGATGAGCACCCACGGCTTCACCGTGGTTGCCCAGGGCGAC
CAGGCGCGCATCGTGCCCAACGCCGAGGCCAAGACCGAGGCCGGCGGCGGCCAGAGCGCGCCGGATCGCCTG
GAGACGCGGGTGATCCAGGTGCAGCAGAGCCCGGTATCGGAACTCATCCCGCTGATCCGTCCGCTGGTCCCA
CAATATGGCCACCTCGCCGCGGTGCCCTCGGCCAACGCGCTGATCATCAGCGACCGCAGCGCCAATATCGCG
CGAATCGAAGACGTGATCCGCCAGCTCGACCAGAAGGGCAGCCACGACTACAGCGTGATCAACCTGCGCTAC
GGCTGGGTGATGGACGCCGCCGAGGTGCTCAACAACGCCATGAGCCGCGGCCAGGCCAAGGGCGCGGCGGGC
GCCCAGGTGATCGCCGACGCGCGCACCAACCGCCTGATCATCCTCGGCCCGCCGCAGGCGCGCGCCAAGCTG
GTGCAACTGGCGCAGTCGCTGGACACCCCGACCGCGCGCTCGGCCAATACCCGGGTGATCCGCCTGCGCCAC
AACGACGCCAAGACCCTCGCGGAAACCCTCGGCCAGATTTCCGAAGGCATGAAGAACAACGGCGGCCAGGGC
GGCGAACAGACCGGCGGCGGCCGACCGAGCAACATCCTGATCCGTGCCGACGAAAGCACCAACGCCCTGGTC
CTGCTGGCCGACCCGGACACGGTCAACGCCCTCGAGGACATCGTTCGCCAGCTCGACGTGCCGCGTGCCCAG
GTATTGGTGGAGGCGGCCATCGTCGAGATCTCCGGCGACATCCAGGATGCCGTCGGCGTGCAATGGGCGATC
AACAAGGGCGGCATGGGCGGAACCAAGACCAACTTCGCCAATACCGGACTGTCCATCGGCACCCTGCTGCAA
TCGCTCGAGAGCAACAAGGCACCGGAATCCATCCCCGACGGCGCCATCGTCGGCATCGGCAGCAGCAGCTTC
GGCGCGCTGGTCACCGCGCTCTCGGCCAACACCAAGAGCAACCTGCTGTCGACCCCGAGCCTGTTGACCCTG
GACAACCAGAAAGCGGAGATTCTGGTCGGCCAGAACGTACCGTTCCAGACCGGCTCCTACACCACCAACAGC
GAAGGTTCGAGCAACCCGTTCACCACCGTGGAGCGCAAGGATATCGGCGTCAGCCTCAAGGTCACTCCGCAC
ATCAACGACGGCGCGGCCCTGCGCCTGGAGATCGAGCAGGAGATCTCGGCCCTGCTGCCCAACGCCCAGCAG
CGCAACAATACCGACCTGATCACCAGCAAGCGCTCGATCAAGAGCACCATCCTCGCCGAGAACGGCCAGGTG
ATCGTGATCGGCGGCCTGATCCAGGACGACGTTTCCCAAGCCGAGTCGAAGGTTCCCCTGCTCGGGGACATC
CCATTCCTCGGTCGCCTGTTCCGTTCCACCAAGGACACCCACACCAAGCGCAACCTGATGGTCTTCCTGCGT
CCTACGGTGGTCCGCGACAGCGCCGGTCTCGCCGCGCTCTCGGGCAAGAAATACAGCGACATCCGGGTCATC
GACGGCACTCGCGGCCCGGAGGGACGACCCAGCATCCTGCCGACCAACGCCAACCAGTTGTTCGATGGACAG
GCCGTCGATCTGCGCGAACTGAAGACGGAATAA
Translation:
MSQPLLRALFAPSSRSYVPAVLLSLALGIQAAHAENSGGNAFVPAGNQQEAHWTINLKDADIREFIDQISEI
TGETFVVDPRVKGQVSVVSKAQLSLSEVYQLFLSVMSTHGFTVVAQGDQARIVPNAEAKTEAGGGQSAPDRL
ETRVIQVQQSPVSELIPLIRPLVPQYGHLAAVPSANALIISDRSANIARIEDVIRQLDQKGSHDYSVINLRY
GWVMDAAEVLNNAMSRGQAKGAAGAQVIADARTNRLIILGPPQARAKLVQLAQSLDTPTARSANTRVIRLRH
NDAKTLAETLGQISEGMKNNGGQGGEQTGGGRPSNILIRADESTNALVLLADPDTVNALEDIVRQLDVPRAQ
VLVEAAIVEISGDIQDAVGVQWAINKGGMGGTKTNFANTGLSIGTLLQSLESNKAPESIPDGAIVGIGSSSF
GALVTALSANTKSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTNSEGSSNPFTTVERKDIGVSLKVTPH
INDGAALRLEIEQEISALLPNAQQRNNTDLITSKRSIKSTILAENGQVIVIGGLIQDDVSQAESKVPLLGDI
PFLGRLFRSTKDTHTKRNLMVFLRPTVVRDSAGLAALSGKKYSDIRVIDGTRGPEGRPSILPTNANQLFDGQ
AVDLRELKTE*
AnnotationID:426GeneID:417
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 06:06:49
Gene Name:xcpQ
Confidence Code:1
GeneProduct: general secretion pathway protein D
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(19) Protein secretion/export apparatus
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1450,pfam00263
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAC83352.1| (AF092918) outer membrane secretion protein Q [Pseudomonas
           alcaligenes]
          Length = 649

 Score =  808 bits (2087), Expect = 0.0
 Identities = 423/618 (68%), Positives = 514/618 (83%), Gaps = 14/618 (2%)

>gb|AAC76350.1| (AE000409) putative general protein secretion protein [Escherichia
           coli K12]
          Length = 654

 Score =  385 bits (990), Expect = e-106
 Identities = 224/602 (37%), Positives = 345/602 (57%), Gaps = 33/602 (5%)






 
Structural Features:
COG1450, PulD, Type II secretory pathway, component PulD 
[Cell motility and secretion / Intracellular trafficking and secretion]
CD-Length = 587 residues,  98.8% aligned
Score =  439 bits (1131), Expect = 4e-124
Identities = 228/632 (36%), Positives = 332/632 (52%), Gaps = 57/632 (9%)

pfam00263, Secretin_C, Bacterial type II and III secretion system protein.
CD-Length = 232 residues, 100.0% aligned
Score =  204 bits (521), Expect = 3e-53
Identities = 103/245 (42%), Positives = 139/245 (56%), Gaps = 14/245 (5%)






   
Genomic Context:






   
Comment:


















    ReferenceID:837




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17979




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32420




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:417_cdd.html


    		




 
URL:

















    ReferenceID:33476




  
Author/Investigator(s):
        Brok R, Van Gelder P, Winterhalter M, Ziese U, Koster AJ, de Cock H, Koster M, Tommassen J, Bitter W.





  
Title:
        The C-terminal domain of the Pseudomonas secretin XcpQ forms oligomeric rings with pore activity.




  
PubMed:
        10600375


MedLine:
        




    
Source:
J Mol Biol. 1999 Dec 17;294(5):1169-79.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10600375

















    ReferenceID:33477




  
Author/Investigator(s):
        Filloux A, Michel G, Bally M.





  
Title:
        GSP-dependent protein secretion in gram-negative bacteria: the Xcp system of Pseudomonas aeruginosa.




  
PubMed:
        9818381


MedLine:
        




    
Source:
FEMS Microbiol Rev. 1998 Sep;22(3):177-98.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9818381

















    ReferenceID:33478




  
Author/Investigator(s):
        Martinez A, Ostrovsky P, Nunn DN.





  
Title:
        Identification of an additional member of the secretin superfamily of proteins in Pseudomonas aeruginosa that is able to function in type II protein secretion.




  
PubMed:
        9680212


MedLine:
        




    
Source:
Mol Microbiol. 1998 Jun;28(6):1235-46.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9680212

















    ReferenceID:33479




  
Author/Investigator(s):
        Bitter W, Koster M, Latijnhouwers M, de Cock H, Tommassen J.





  
Title:
        Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa.




  
PubMed:
        9466268


MedLine:
        




    
Source:
Mol Microbiol. 1998 Jan;27(1):209-19.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9466268









           
Homologs By Global Alignment 

           

       



     
Gene ID:417
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
706
                           PA3105_tr
                           translation of PA3105
                           658
                           99.69
                           99.69
                           0
                           3248.0
     

     
     
31784
                           gb|AAG06493.1|AE004734_11
                           (AE004734) general secretion pathway protein D [Pseudomonas aeruginosa PAO1]
                           658
                           99.69
                           99.69
                           0
                           3248.0
     

     
     
31785
                           emb|CAA48582.1|
                           (X68594) XcpQ [Pseudomonas aeruginosa]
                           658
                           99.69
                           99.69
                           0
                           3248.0
     

     
     
31786
                           gb|AAC83352.1|
                           (AF092918) outer membrane secretion protein Q [Pseudomonas alcaligenes]
                           676
                           64.34
                           78.25
                           45
                           2112.0
     

     
     
31787
                           gb|AAC38777.1|
                           (AF044261) XqhA [Pseudomonas aeruginosa]
                           739
                           54.53
                           68.47
                           107
                           1963.0
     

     






      

          
GC ORFID: 43419How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3105Glimmer Score: 

          
Start: 2869995Stop: 2871971

          
Length: 1977


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA3105 translation of PA3105Homolog Bit Score 1255.0

          
Other Homologs:  t_PA3105 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCCAACCTTTGCTCCGCGCCCTGTTTGCCCCTTCCAGTCGTTCGTACGTTCCCGCCGTCCTTCTCAGC 
CTGGCCCTCGGCATCCAGGCGGCGCACGCCGAAAACAGCGGCGGGAACGCCTTCGTCCCGGCCGGCAACCAG 
CAGGAGGCGCACTGGACGATCAACCTCAAGGATGCCGACATCCGCGAATTCATCGACCAGATTTCCGAAATC 
ACCGGCGAGACCTTCGTCGTCGACCCGCGGGTCAAGGGCCAGGTCAGCGTGGTCTCCAAGGCCCAGCTCTCG 
TTGAGCGAGGTCTACCAGTTGTTCCTCTCGGTGATGAGCACCCACGGCTTCACCGTGGTTGCCCAGGGCGAC 
CAGGCGCGCATCGTGCCCAACGCCGAGGCCAAGACCGAGGCCGGCGGCGGCCAGAGCGCGCCGGATCGCCTG 
GAGACGCGGGTGATCCAGGTGCAGCAGAGCCCGGTATCGGAACTCATCCCGCTGATCCGTCCGCTGGTCCCA 
CAATATGGCCACCTCGCCGCGGTGCCCTCGGCCAACGCGCTGATCATCAGCGACCGCAGCGCCAATATCGCG 
CGAATCGAAGACGTGATCCGCCAGCTCGACCAGAAGGGCAGCCACGACTACAGCGTGATCAACCTGCGCTAC 
GGCTGGGTGATGGACGCCGCCGAGGTGCTCAACAACGCCATGAGCCGCGGCCAGGCCAAGGGCGCGGCGGGC 
GCCCAGGTGATCGCCGACGCGCGCACCAACCGCCTGATCATCCTCGGCCCGCCGCAGGCGCGCGCCAAGCTG 
GTGCAACTGGCGCAGTCGCTGGACACCCCGACCGCGCGCTCGGCCAATACCCGGGTGATCCGCCTGCGCCAC 
AACGACGCCAAGACCCTCGCGGAAACCCTCGGCCAGATTTCCGAAGGCATGAAGAACAACGGCGGCCAGGGC 
GGCGAACAGACCGGCGGCGGCCGACCGAGCAACATCCTGATCCGTGCCGACGAAAGCACCAACGCCCTGGTC 
CTGCTGGCCGACCCGGACACGGTCAACGCCCTCGAGGACATCGTTCGCCAGCTCGACGTGCCGCGTGCCCAG 
GTATTGGTGGAGGCGGCCATCGTCGAGATCTCCGGCGACATCCAGGATGCCGTCGGCGTGCAATGGGCGATC 
AACAAGGGCGGCATGGGCGGAACCAAGACCAACTTCGCCAATACCGGACTGTCCATCGGCACCCTGCTGCAA 
TCGCTCGAGAGCAACAAGGCACCGGAATCCATCCCCGACGGCGCCATCGTCGGCATCGGCAGCAGCAGCTTC 
GGCGCGCTGGTCACCGCGCTCTCGGCCAACACCAAGAGCAACCTGCTGTCGACCCCGAGCCTGTTGACCCTG 
GACAACCAGAAAGCGGAGATTCTGGTCGGCCAGAACGTACCGTTCCAGACCGGCTCCTACACCACCAACAGC 
GAAGGTTCGAGCAACCCGTTCACCACCGTGGAGCGCAAGGATATCGGCGTCAGCCTCAAGGTCACTCCGCAC 
ATCAACGACGGCGCGGCCCTGCGCCTGGAGATCGAGCAGGAGATCTCGGCCCTGCTGCCCAACGCCCAGCAG 
CGCAACAATACCGACCTGATCACCAGCAAGCGCTCGATCAAGAGCACCATCCTCGCCGAGAACGGCCAGGTG 
ATCGTGATCGGCGGCCTGATCCAGGACGACGTTTCCCAAGCCGAGTCGAAGGTTCCCCTGCTCGGGGACATC 
CCATTCCTCGGTCGCCTGTTCCGTTCCACCAAGGACACCCACACCAAGCGCAACCTGATGGTCTTCCTGCGT 
CCTACGGTGGTCCGCGACAGCGCCGGTCTCGCCGCGCTCTCGGGCAAGAAATACAGCGACATCCGGGTCATC 
GACGGCACTCGCGGCCCGGAGGGACGACCCAGCATCCTGCCGACCAACGCCAACCAGTTGTTCGATGGACAG 
GCCGTCGATCTGCGCGAACTGAAGACGGAATAA