ViewGene
Locus Name:
GeneID:
Location:

GeneID:406
TrivialName: PA14_62860
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_62860
PAO1 Ortholog Locus:PA4751
Sequence Length:1920
Protein Length:639
Start: 5609630
Stop: 5607711
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08137.1|AE004888_12 (AE004888) cell division protein FtsH [Pseudomonas aeruginosa PAO1]
Identities = 639/639 (100%), Positives = 639/639 (100%)
Sequence:
ATGGCAAAGAATCTGATTCTGTGGCTGATCATCGCGGCGGTACTGGTGACCGTGATGAACAATTTCTCGAGC
CCGAGCGAGCCACAGACGCTGAACTACTCGGACTTCATCCAGCAGGTCAAGGATGGCAAGGTCGAGCGAGTG
ACCGTGGATGGCTATGTCATCACCGGCAAGCGTAGCGACGGCGATACCTTCAAGACCATCCGCCCGGCGATC
CAGGACAACGGCCTGATCGGCGACCTGGTCAACAACAACGTCGTGGTCGAGGGCAAGCAGCCCGAACAGCAG
AGCATCTGGACCCAGTTGCTGGTCGCCAGCTTCCCGATCCTGGTGATCATCGCCGTCTTCATGTTCTTCATG
CGCCAGATGCAGGGCGGCGGCGGCGGTCGCGGCGGCCCGATGAGCTTCGGCAAGAGCAAGGCGCGCCTGCTG
TCCGAGGACCAGGTCAAGACCACCTTCGCTGACGTCGCCGGCTGCGACGAGGCCAAGGAGGAGGTCAGCGAG
CTGGTCGAGTTCCTTCGCGATCCGGGCAAGTTCCAGCGCCTGGGCGGCCGTATCCCGCGCGGCGTGCTGATG
GTCGGCCCGCCCGGCACCGGCAAGACCCTGCTGGCCAAGGCCATCGCCGGCGAAGCCAAGGTGCCGTTCTTC
ACCATTTCCGGTTCCGACTTCGTCGAGATGTTCGTCGGCGTGGGCGCCTCCCGTGTCCGCGACATGTTCGAC
CAGGCCAAGAAGCACGCGCCGTGCATCATCTTCATCGACGAGATCGACGCCGTCGGCCGCCATCGCGGCGCC
GGCTTGGGCGGCGGTCACGACGAGCGCGAGCAGACCCTCAACCAGTTGCTGGTGGAGATGGATGGCTTCGAG
ATGAACGATGGCATCATCGTCATCGCTGCCACCAACCGTCCGGACGTTCTGGACCCGGCGCTGCTGCGTCCG
GGCCGCTTCGACCGCCAGGTGGTGGTCGGCTTGCCGGATATCCGCGGGCGCGAACAGATCCTCAAGGTGCAC
ATGCGCAAGGTGCCGCTGGGCGACCATGTCGATCCTGCCGTCATCGCCCGCGGTACGCCCGGTTTCTCCGGC
GCCGACCTGGCCAACCTGGTCAACGAGGCCTCGCTATTCGCCGCGCGCTCCAACAAGCGCATCGTCGACATG
CGCGAGTTCGAGCTGGCCAAGGACAAGATCATGATGGGCGCCGAGCGCAAGACCATGGTCATGTCCGAGAAG
GAGAAGCGCAACACCGCCTACCACGAGGCCGGCCACGCCATCGTCGGTCGCCTGGTGCCGGAGCATGACCCG
GTCTACAAGGTGTCCATCATTCCGCGCGGACGTGCCCTGGGCGTGACCATGTTCCTCCCCGAGGAAGATCGC
TACAGCCTGTCCAAGCGCGCGCTGGAAAGCCAGATCTGCTCGCTGTTCGGCGGCCGTATCGCGGAAGAGATG
ACCCTCGGCTTTGAAGGCGTCACCACTGGCGCTTCCAACGACATCATGCGTGCTACCCAGTTGGCGCGGAAC
ATGGTGACCAAGTGGGGTCTGTCCGAGAAACTCGGCCCGCTGATGTACGCGGAGGAGGAGGGCGAGGTGTTC
CTCGGCCGTAGCGCCGGCAGCCAGCACGCCAATGTGTCGGGCGAGACCGCCAAGATGATCGACCAGGAAGTC
CGGCGCATCATCGACGACTGCTACGGTACCGCCAAGCGACTGCTCGACGAGAACCGCGACAAGCTGGAGATG
ATGGCCGACGCACTGATGAAGTACGAGACCATCGACTCCGACCAGATCGACGACATCATGGCCGGTCGCGTG
CCGCGCGAGCCGCGTGACTGGCAGGGTGGTTCGGGTACCGGCACCCCGCCGGCCAACCTGGAAGAGTCGGGC
CGCCGCGAGAACACCCCTCCCATCGGTGGGCCGGCCGGCGAGCACTGA
Translation:
MAKNLILWLIIAAVLVTVMNNFSSPSEPQTLNYSDFIQQVKDGKVERVTVDGYVITGKRSDGDTFKTIRPAI
QDNGLIGDLVNNNVVVEGKQPEQQSIWTQLLVASFPILVIIAVFMFFMRQMQGGGGGRGGPMSFGKSKARLL
SEDQVKTTFADVAGCDEAKEEVSELVEFLRDPGKFQRLGGRIPRGVLMVGPPGTGKTLLAKAIAGEAKVPFF
TISGSDFVEMFVGVGASRVRDMFDQAKKHAPCIIFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFE
MNDGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDIRGREQILKVHMRKVPLGDHVDPAVIARGTPGFSG
ADLANLVNEASLFAARSNKRIVDMREFELAKDKIMMGAERKTMVMSEKEKRNTAYHEAGHAIVGRLVPEHDP
VYKVSIIPRGRALGVTMFLPEEDRYSLSKRALESQICSLFGGRIAEEMTLGFEGVTTGASNDIMRATQLARN
MVTKWGLSEKLGPLMYAEEEGEVFLGRSAGSQHANVSGETAKMIDQEVRRIIDDCYGTAKRLLDENRDKLEM
MADALMKYETIDSDQIDDIMAGRVPREPRDWQGGSGTGTPPANLEESGRRENTPPIGGPAGEH*
AnnotationID:415GeneID:406
AnnotatorUID: diggins
Modification Date/Time: 2005-04-27 07:07:00
Gene Name:ftsH
Confidence Code:2
GeneProduct:cell division protein FtsH
Cell Localization:()
Synonyms:hflB
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(6) Cell division
Alternate Gene Product Name:Zn metallo-peptidase, integral membrane cell division protein
Functional Category Confidence Code:5
COGs:COG0465,pfam01434,pfam00004,pfam06480
Secondary Functional Category(ies):posttranslational modification, protein turnover, chaperones
EC Number:3.4.24.-
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70290.1|AE016669_8 (AE016791) cell division protein FtsH [Pseudomonas putida KT2440]
          Length = 637

 Score = 1153 bits (2983), Expect = 0.0
 Identities = 583/639 (91%), Positives = 610/639 (95%), Gaps = 5/639 (0%)

>gb|AAO57945.1| (AE016872) cell division protein FtsH [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 634

 Score = 1124 bits (2907), Expect = 0.0
 Identities = 570/640 (89%), Positives = 603/640 (94%), Gaps = 7/640 (1%)

>dbj|BAB37480.1| (AP002564) cell division protein HflB/FtsH protease [Escherichia
           coli O157:H7]
          Length = 644

 Score =  840 bits (2170), Expect = 0.0
 Identities = 432/631 (68%), Positives = 518/631 (82%), Gaps = 13/631 (2%)








 
Structural Features:
COG0465, HflB, ATP-dependent Zn proteases 
[Posttranslational modification, protein turnover, chaperones]
CD-Length = 596 residues, 100.0% aligned
Score =  792 bits (2048), Expect = 0.0
Identities = 372/602 (61%), Positives = 459/602 (76%), Gaps = 9/602 (1%)

pfam01434, Peptidase_M41, Peptidase family M41.
CD-Length = 214 residues, 100.0% aligned
Score =  287 bits (736), Expect = 3e-78
Identities = 111/215 (51%), Positives = 161/215 (74%), Gaps = 2/215 (0%)

pfam00004, AAA, ATPase family associated with various 
cellular activities (AAA).
CD-Length = 186 residues, 100.0% aligned
Score =  227 bits (581), Expect = 2e-60
Identities = 112/188 (59%), Positives = 133/188 (70%), Gaps = 2/188 (1%)

pfam06480, FtsH_ext, FtsH Extracellular.
CD-Length = 138 residues, 100.0% aligned
Score =  151 bits (382), Expect = 3e-37
Identities = 62/140 (44%), Positives = 85/140 (60%), Gaps = 7/140 (5%)






   
Genomic Context:






   
Comment:


















    ReferenceID:815




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17957




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:37665




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:406_cdd.html


    		




 
URL:

















    ReferenceID:37721




  
Author/Investigator(s):
        Ogura T, Tomoyasu T, Yuki T, Morimura S, Begg KJ, Donachie WD, Mori H, Niki H, Hiraga S.





  
Title:
        Structure and function of the ftsH gene in Escherichia coli.




  
PubMed:
        1925026


MedLine:
        




    
Source:
Res Microbiol. 1991 Feb-Apr;142(2-3):279-82.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1925026

















    ReferenceID:37722




  
Author/Investigator(s):
        Tomoyasu T, Yuki T, Morimura S, Mori H, Yamanaka K, Niki H, Hiraga S, Ogura T.





  
Title:
        The Escherichia coli FtsH protein is a prokaryotic member of a protein family of putative ATPases involved in membrane functions, cell cycle control, and gene expression.




  
PubMed:
        8444796


MedLine:
        




    
Source:
J Bacteriol. 1993 Mar;175(5):1344-51.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8444796









           
Homologs By Global Alignment 

           

       



     
Gene ID:406
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
690
                           PA4751_tr
                           translation of PA4751
                           639
                           99.99
                           99.99
                           0
                           3279.0
     

     
     
31292
                           gb|AAG08137.1|AE004888_12
                           (AE004888) cell division protein FtsH [Pseudomonas aeruginosa PAO1]
                           639
                           99.99
                           99.99
                           0
                           3279.0
     

     
     
31293
                           gb|AAN70290.1|AE016669_8
                           (AE016791) cell division protein FtsH [Pseudomonas putida KT2440]
                           642
                           90.80
                           95.01
                           8
                           2988.0
     

     
     
31294
                           gb|AAO57945.1|
                           (AE016872) cell division protein FtsH [Pseudomonas syringae pv. tomato str. DC3000]
                           640
                           89.06
                           94.21
                           7
                           2916.0
     

     
     
31300
                           emb|CAD07813.1|
                           (AL627278) cell division protein [Salmonella enterica subsp. enterica serovar Typhi]
                           653
                           67.38
                           80.09
                           23
                           2194.0
     

     






      

          
GC ORFID: 43408How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4751Glimmer Score: 

          
Start: 4873310Stop: 4871391

          
Length: 1920


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4751 translation of PA4751Homolog Bit Score 1267.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5485 (ORF: BLASTX 1125.0), t_PA4751 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGGCAAAGAATCTGATTCTGTGGCTGATCATCGCGGCGGTACTGGTGACCGTGATGAACAATTTCTCGAGC 
CCGAGCGAGCCACAGACGCTGAACTACTCGGACTTCATCCAGCAGGTCAAGGATGGCAAGGTCGAGCGAGTG 
ACCGTGGATGGCTATGTCATCACCGGCAAGCGTAGCGACGGCGATACCTTCAAGACCATCCGCCCGGCGATC 
CAGGACAACGGCCTGATCGGCGACCTGGTCAACAACAACGTCGTGGTCGAGGGCAAGCAGCCCGAACAGCAG 
AGCATCTGGACCCAGTTGCTGGTCGCCAGCTTCCCGATCCTGGTGATCATCGCCGTCTTCATGTTCTTCATG 
CGCCAGATGCAGGGCGGCGGCGGCGGTCGCGGCGGCCCGATGAGCTTCGGCAAGAGCAAGGCGCGCCTGCTG 
TCCGAGGACCAGGTCAAGACCACCTTCGCTGACGTCGCCGGCTGCGACGAGGCCAAGGAGGAGGTCAGCGAG 
CTGGTCGAGTTCCTTCGCGATCCGGGCAAGTTCCAGCGCCTGGGCGGCCGTATCCCGCGCGGCGTGCTGATG 
GTCGGCCCGCCCGGCACCGGCAAGACCCTGCTGGCCAAGGCCATCGCCGGCGAAGCCAAGGTGCCGTTCTTC 
ACCATTTCCGGTTCCGACTTCGTCGAGATGTTCGTCGGCGTGGGCGCCTCCCGTGTCCGCGACATGTTCGAC 
CAGGCCAAGAAGCACGCGCCGTGCATCATCTTCATCGACGAGATCGACGCCGTCGGCCGCCATCGCGGCGCC 
GGCTTGGGCGGCGGTCACGACGAGCGCGAGCAGACCCTCAACCAGTTGCTGGTGGAGATGGATGGCTTCGAG 
ATGAACGATGGCATCATCGTCATCGCTGCCACCAACCGTCCGGACGTTCTGGACCCGGCGCTGCTGCGTCCG 
GGCCGCTTCGACCGCCAGGTGGTGGTCGGCTTGCCGGATATCCGCGGGCGCGAACAGATCCTCAAGGTGCAC 
ATGCGCAAGGTGCCGCTGGGCGACCATGTCGATCCTGCCGTCATCGCCCGCGGTACGCCCGGTTTCTCCGGC 
GCCGACCTGGCCAACCTGGTCAACGAGGCCTCGCTATTCGCCGCGCGCTCCAACAAGCGCATCGTCGACATG 
CGCGAGTTCGAGCTGGCCAAGGACAAGATCATGATGGGCGCCGAGCGCAAGACCATGGTCATGTCCGAGAAG 
GAGAAGCGCAACACCGCCTACCACGAGGCCGGCCACGCCATCGTCGGTCGCCTGGTGCCGGAGCATGACCCG 
GTCTACAAGGTGTCCATCATTCCGCGCGGACGTGCCCTGGGCGTGACCATGTTCCTCCCCGAGGAAGATCGC 
TACAGCCTGTCCAAGCGCGCGCTGGAAAGCCAGATCTGCTCGCTGTTCGGCGGCCGTATCGCGGAAGAGATG 
ACCCTCGGCTTTGAAGGCGTCACCACTGGCGCTTCCAACGACATCATGCGTGCTACCCAGTTGGCGCGGAAC 
ATGGTGACCAAGTGGGGTCTGTCCGAGAAACTCGGCCCGCTGATGTACGCGGAGGAGGAGGGCGAGGTGTTC 
CTCGGCCGTAGCGCCGGCAGCCAGCACGCCAATGTGTCGGGCGAGACCGCCAAGATGATCGACCAGGAAGTC 
CGGCGCATCATCGACGACTGCTACGGTACCGCCAAGCGACTGCTCGACGAGAACCGCGACAAGCTGGAGATG 
ATGGCCGACGCACTGATGAAGTACGAGACCATCGACTCCGACCAGATCGACGACATCATGGCCGGTCGCGTG 
CCGCGCGAGCCGCGTGACTGGCAGGGTGGTTCGGGTACCGGCACCCCGCCGGCCAACCTGGAAGAGTCGGGC 
CGCCGCGAGAACACCCCTCCCATCGGTGGGCCGGCCGGCGAGCACTGA