ViewGene
Locus Name:
GeneID:
Location:

GeneID:4055
TrivialName: PA14_60860
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_60860
PAO1 Ortholog Locus:PA4600
Sequence Length:564
Protein Length:187
Start: 5428030
Stop: 5428593
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07988.1|AE004874_1 (AE004874) transcriptional regulator NfxB [Pseudomonas aeruginosa PAO1]
Identities = 185/187 (98%), Positives = 185/187 (98%)
Sequence:
ATGACCCTGATTTCCCATGACGAGCGACTCATCAAGGCGCTGGCAGTCGCCATCGTCGACCACCCGCGAGCG
ACGCTGAAAGAACTGGCCGAGGCGGCCGGCGTAAGCAAGGCCACCCTGCACCGCTTCTGCGGCACGCGGGAC
AACCTGGTGCAGATGCTCGAGGGCCACGGAGAGACCGTACTGAACCAGATCATCCAGGCCTGCGACCTGGAG
CATGCCGAGCCTCTGGAGGCGTTGCAGCGCCTGATCAAGGAACACCTCACCCACCGCGAGCTGCTGGTATTC
CTGGTATTCCAGTACCGCCCGGACTTCCTCGACCCGCACGGCGAAGGCGCACGCTGGCAGTCCTACCTGGAA
GCGCTGGACGCCTTCTTCCTGCGCGGACAGCAGAAAGGCGTGTTTCGCATCGACATCACGGCAGCCGTGTTC
ACCGAACTGTTCATCACCCTGGTCTACGGCATGGTCGATGCGGAACGTCGCGGACGGGCGGCCAGCTCCAAT
TCCGCGCATACCCTGGAGCAGATGTTCCTCCACGGCGCCTCCAATCCGGCGCGCTCCTGA
Translation:
MTLISHDERLIKALAVAIVDHPRATLKELAEAAGVSKATLHRFCGTRDNLVQMLEGHGETVLNQIIQACDLE
HAEPLEALQRLIKEHLTHRELLVFLVFQYRPDFLDPHGEGARWQSYLEALDAFFLRGQQKGVFRIDITAAVF
TELFITLVYGMVDAERRGRAASSNSAHTLEQMFLHGASNPARS*
AnnotationID:4062GeneID:4055
AnnotatorUID: diggins
Modification Date/Time: 2005-05-06 06:06:51
Gene Name:nfxB
Confidence Code:1
GeneProduct:transcriptional regulatory protein NfxB
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(25) Transcriptional regulators
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN68428.1|AE016475_7 (AE016784) transcriptional regulator NfxB [Pseudomonas putida
           KT2440]
          Length = 185

 Score =  248 bits (633), Expect = 1e-65
 Identities = 123/180 (68%), Positives = 146/180 (81%)


>gb|AAO56098.1| (AE016865) transcriptional regulatory protein NfxB [Pseudomonas
           syringae pv. tomato str. DC3000]
          Length = 184

 Score =  218 bits (556), Expect = 1e-56
 Identities = 109/179 (60%), Positives = 139/179 (77%)








 
Structural Features:
CDD Search: No hits above 0.01 threshold.






   
Genomic Context:






   
Comment:


















    ReferenceID:8112




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:25255




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33322




  
Author/Investigator(s):
        Poole K, Gotoh N, Tsujimoto H, Zhao Q, Wada A, Yamasaki T, Neshat S, Yamagishi J, Li XZ, Nishino T.





  
Title:
        Overexpression of the mexC-mexD-oprJ efflux operon in nfxB-type multidrug-resistant strains of Pseudomonas aeruginosa.




  
PubMed:
        8878035


MedLine:
        




    
Source:
Mol Microbiol. 1996 Aug;21(4):713-24.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8878035

















    ReferenceID:33323




  
Author/Investigator(s):
        Masuda N, Gotoh N, Ohya S, Nishino T.





  
Title:
        Quantitative correlation between susceptibility and OprJ production in NfxB mutants of Pseudomonas aeruginosa.




  
PubMed:
        8849250


MedLine:
        




    
Source:
Antimicrob Agents Chemother. 1996 Apr;40(4):909-13.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8849250

















    ReferenceID:33324




  
Author/Investigator(s):
        Shiba T, Ishiguro K, Takemoto N, Koibuchi H, Sugimoto K.





  
Title:
        Purification and characterization of the Pseudomonas aeruginosa NfxB protein, the negative regulator of the nfxB gene.




  
PubMed:
        7592337


MedLine:
        




    
Source:
J Bacteriol. 1995 Oct;177(20):5872-7.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7592337

















    ReferenceID:33325




  
Author/Investigator(s):
        Okazaki T, Hirai K.





  
Title:
        Cloning and nucleotide sequence of the Pseudomonas aeruginosa nfxB gene, conferring resistance to new quinolones.




  
PubMed:
        1330820


MedLine:
        




    
Source:
FEMS Microbiol Lett. 1992 Oct 1;76(1-2):197-202.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1330820









           
Homologs By Global Alignment 

           

       



     
Gene ID:4055
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6297
                           PA4600_tr
                           translation of PA4600
                           187
                           98.93
                           98.93
                           0
                           939.0
     

     
     
173327
                           gb|AAG07988.1|AE004874_1
                           (AE004874) transcriptional regulator NfxB [Pseudomonas aeruginosa PAO1]
                           187
                           98.93
                           98.93
                           0
                           939.0
     

     
     
173328
                           emb|CAA46598.1|
                           (X65646) hypothetical protein [Pseudomonas aeruginosa]
                           187
                           98.39
                           98.39
                           0
                           934.0
     

     
     
173329
                           gb|AAO47352.1|
                           (AY180395) truncated NfxB [Pseudomonas aeruginosa]
                           192
                           70.83
                           71.35
                           50
                           684.0
     

     
     
173330
                           gb|AAN68428.1|AE016475_7
                           (AE016784) transcriptional regulator NfxB [Pseudomonas putida KT2440]
                           190
                           65.26
                           77.36
                           8
                           629.0
     

     






      

          
GC ORFID: 47057How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4600Glimmer Score: 

          
Start: 4691710Stop: 4692273

          
Length: 564


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4600 translation of PA4600Homolog Bit Score 366.0

          
Other Homologs:  psyr_15may02_Scaffold1_revised_gene1250 (ORF: BLASTX 219.0), t_PA4600 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACCCTGATTTCCCATGACGAGCGACTCATCAAGGCGCTGGCAGTCGCCATCGTCGACCACCCGCGAGCG 
ACGCTGAAAGAACTGGCCGAGGCGGCCGGCGTAAGCAAGGCCACCCTGCACCGCTTCTGCGGCACGCGGGAC 
AACCTGGTGCAGATGCTCGAGGGCCACGGAGAGACCGTACTGAACCAGATCATCCAGGCCTGCGACCTGGAG 
CATGCCGAGCCTCTGGAGGCGTTGCAGCGCCTGATCAAGGAACACCTCACCCACCGCGAGCTGCTGGTATTC 
CTGGTATTCCAGTACCGCCCGGACTTCCTCGACCCGCACGGCGAAGGCGCACGCTGGCAGTCCTACCTGGAA 
GCGCTGGACGCCTTCTTCCTGCGCGGACAGCAGAAAGGCGTGTTTCGCATCGACATCACGGCAGCCGTGTTC 
ACCGAACTGTTCATCACCCTGGTCTACGGCATGGTCGATGCGGAACGTCGCGGACGGGCGGCCAGCTCCAAT 
TCCGCGCATACCCTGGAGCAGATGTTCCTCCACGGCGCCTCCAATCCGGCGCGCTCCTGA