ViewGene
Locus Name:
GeneID:
Location:

GeneID:399
TrivialName: PA14_49560
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_49560
PAO1 Ortholog Locus:PA1148
Sequence Length:1908
Protein Length:635
Start: 4407441
Stop: 4409348
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG04537.1|AE004544_9 (AE004544) exotoxin A precursor [Pseudomonas aeruginosa PAO1]
Identities = 630/638 (98%), Positives = 632/638 (99%), Gaps = 3/638 (0%)
Sequence:
ATGCACCTGATACCCCATTGGATCCCCCTGGTCGCCAGCCTCGGCCTGCTCGCCGGCGGCTCGTTCGCGTCC
GCCGCCGAGGAAGCCTTCGACCTCTGGAACGAATGCGCCAAGGCCTGCGTGCTCGACCTCAAGGACGGCGTG
CGTTCCAGCCGCATGAGCGTCGACCCGGCCATCGCCGACACCAACGGCCAGGGCGTGCTGCACTACTCCATG
GTCCTGGAGGGCGGCAACGACGCGCTCAAGCTGGCCATCGACAACGCCCTCAGCATCACCAGCGACGGCCTG
ACCATCCGCCTCGAAGGCGGCGTCGAGCCGAACAAGCCGGTGCGCTACAGCTACACGCGCCAGGCGCGCGGC
AGTTGGTCGCTGAACTGGCTGGTACCGATCGGCCACGAGAAGCCCTCGAACATCAAGGTGTTCATCCACGAA
CTGAACGCCGGTAACCAGCTCAGCCACATGTCGCCGATCTACACCATCGAGATGGGCGACGAGTTGCTGGCG
AAGCTGGCGCGCGATGCCACCTTCTTCGTCAGGGCGCACGAGAGCAACGAGATGCAGCCGACGCTCGCCATC
AGCCATGCCGGGGTCAGCGTGGTCATGGCCCAGACCCAGCCGCGCCGGGAAAAGCGCTGGAGCGAATGGGCC
AGCGGCAAGGTGTTGTGCCTGCTCGACCCGCTGGACGGGGTCTACAACTACCTCGCCCAGCAACGCTGCAAC
CTCGACGATACCTGGGAAGGCAAGATCTACCGGGTGCTCGCCGGCAACCCGGCGAAGCATGACCTGGACATC
AAGCCCACGGTCATCAGTCATCGCCTGCACTTCCCCGAGGGCGGCAGCCTGGCCGCGCTGACCGCGCACCAG
GCTTGCCACCTGCCGCTGGAGACTTTCACCCGTCATCGCCAGCCGCGCGGCTGGGAACAACTGGAGCAGTGC
GGCTATCCGGTGCAGCGGCTGGTCGCCCTCTACCTGGCGGCGCGGCTGTCGTGGAACCAGGTCGACCAGGTG
ATCCGCAACGCCCTGGCCAGCCCCGGCAGCGGCGGCGACCTGGGCGAAGCGATCCGCGAGCAGCCGGAGCAG
GCCCGTCTGGCCCTGACCCTGGCCGCCGCCGAGAGCGAGCGCTTCGTCCGGCAGGGCACCGGCAACGACGAG
GCCAGCGCCGACGTGGTGAGCCTGACCTGCCCGGTCGCCGCCGGTGAATGCGCGGGCCCGGCGGACAGCGGC
GACGCCCTGCTGGAGCGCAACTATCCCACTGGCGCGGAGTTCCTCGGCGACGGCGGCGACGTCAGCTTCAGC
ACCCGCGGCACGCAGAACTGGACGGTGGAGCGGCTGCTCCAGGCGCACCGCCAACTGGAGGAGCGCGGCTAT
GTGTTCGTCGGCTACCACGGCACCTTCCTCGAAGCGGCGCAAAGCATCGTCTTCGGCGGGGTGCGCGCGCGC
AGCCAGGACCTCGACGCGATCTGGCGCGGTTTCTATATCGCCGGCGATCCGGCGCTGGCCTACGGCTACGCC
CAGGACCAGGAACCCGACGCGCGCGGCCGGATCCGCAACGGTGCCCTGCTGCGGGTCTATGTGCCGCGCTCG
AGTCTGCCGGGCTTCTACCGCACCGGCCTGACCCTGGCCGCGCCGGAGGCGGCGGGCGAGGTCGAACGGCTG
ATCGGCCATCCGCTGCCGCTGCGCCTGGACGCCATCACCGGCCCCGAGGAGGAAGGCGGGCGCCTGGAGACC
ATTCTCGGCTGGCCGCTGGCCGAGCGCACCGTGGTGATTCCCTCGGCGATCCCCACCGACCCGCGCAACGTC
GGCGGCGACCTCGACCCGTCCAGCATCCCCGACCAGGAACAGGCGATCAGCGCCCTGCCGGACTACGCCAGC
CAGCCCGGCAAACCGTCGCGCGAGGACCTGAAGTAG
Translation:
MHLIPHWIPLVASLGLLAGGSFASAAEEAFDLWNECAKACVLDLKDGVRSSRMSVDPAIADTNGQGVLHYSM
VLEGGNDALKLAIDNALSITSDGLTIRLEGGVEPNKPVRYSYTRQARGSWSLNWLVPIGHEKPSNIKVFIHE
LNAGNQLSHMSPIYTIEMGDELLAKLARDATFFVRAHESNEMQPTLAISHAGVSVVMAQTQPRREKRWSEWA
SGKVLCLLDPLDGVYNYLAQQRCNLDDTWEGKIYRVLAGNPAKHDLDIKPTVISHRLHFPEGGSLAALTAHQ
ACHLPLETFTRHRQPRGWEQLEQCGYPVQRLVALYLAARLSWNQVDQVIRNALASPGSGGDLGEAIREQPEQ
ARLALTLAAAESERFVRQGTGNDEASADVVSLTCPVAAGECAGPADSGDALLERNYPTGAEFLGDGGDVSFS
TRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYA
QDQEPDARGRIRNGALLRVYVPRSSLPGFYRTGLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLET
ILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDQEQAISALPDYASQPGKPSREDLK*
AnnotationID:408GeneID:399
AnnotatorUID: danlee
Modification Date/Time: 2004-09-13 15:03:17
Gene Name:toxA
Confidence Code:1
GeneProduct:exotoxin A precursor
Cell Localization:()
Synonyms:PA1148, eta
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(23) Secreted Factors (toxins, enzymes, alginate)
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:






 
Homology:






 
Structural Features:






   
Genomic Context:






   
Comment:


















    ReferenceID:801




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:17943




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34283




  
Author/Investigator(s):
        Gray GL, Smith DH, Baldridge JS, Harkins RN, Vasil ML, Chen EY, Heyneker HL.





  
Title:
        Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.





  
PubMed:
        84194063


MedLine:
        




    
Source:
Proc Natl Acad Sci U S A. 1984 May;81(9):2645-9.






    
Reference Type:Journal 







    
Data:


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:399
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
665
                           PA1148_tr
                           translation of PA1148
                           638
                           98.74
                           99.05
                           3
                           3295.0
     

     
     
30725
                           gb|AAG04537.1|AE004544_9
                           (AE004544) exotoxin A precursor [Pseudomonas aeruginosa PAO1]
                           638
                           98.74
                           99.05
                           3
                           3295.0
     

     
     
30726
                           gb|AAB59097.1|
                           (K01397) exotoxin type A [Pseudomonas aeruginosa]
                           638
                           98.74
                           99.05
                           3
                           3289.0
     

     
     
30729
                           gb|AAF90005.1|
                           (AF227424) exotoxin A [Pseudomonas aeruginosa]
                           635
                           35.11
                           35.27
                           409
                           1162.0
     

     
     
30727
                           gb|AAF90004.1|
                           (AF227423) exotoxin A [Pseudomonas aeruginosa]
                           635
                           34.96
                           35.43
                           409
                           1165.0
     

     






      

          
GC ORFID: 43401How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA1148Glimmer Score: 

          
Start: 546467Stop: 544560

          
Length: 1908


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAGTruncated Stop: 

          
Homolog: t_PA1148 translation of PA1148Homolog Bit Score 1272.0

          
Other Homologs:  t_PA1148 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCACCTGATACCCCATTGGATCCCCCTGGTCGCCAGCCTCGGCCTGCTCGCCGGCGGCTCGTTCGCGTCC 
GCCGCCGAGGAAGCCTTCGACCTCTGGAACGAATGCGCCAAGGCCTGCGTGCTCGACCTCAAGGACGGCGTG 
CGTTCCAGCCGCATGAGCGTCGACCCGGCCATCGCCGACACCAACGGCCAGGGCGTGCTGCACTACTCCATG 
GTCCTGGAGGGCGGCAACGACGCGCTCAAGCTGGCCATCGACAACGCCCTCAGCATCACCAGCGACGGCCTG 
ACCATCCGCCTCGAAGGCGGCGTCGAGCCGAACAAGCCGGTGCGCTACAGCTACACGCGCCAGGCGCGCGGC 
AGTTGGTCGCTGAACTGGCTGGTACCGATCGGCCACGAGAAGCCCTCGAACATCAAGGTGTTCATCCACGAA 
CTGAACGCCGGTAACCAGCTCAGCCACATGTCGCCGATCTACACCATCGAGATGGGCGACGAGTTGCTGGCG 
AAGCTGGCGCGCGATGCCACCTTCTTCGTCAGGGCGCACGAGAGCAACGAGATGCAGCCGACGCTCGCCATC 
AGCCATGCCGGGGTCAGCGTGGTCATGGCCCAGACCCAGCCGCGCCGGGAAAAGCGCTGGAGCGAATGGGCC 
AGCGGCAAGGTGTTGTGCCTGCTCGACCCGCTGGACGGGGTCTACAACTACCTCGCCCAGCAACGCTGCAAC 
CTCGACGATACCTGGGAAGGCAAGATCTACCGGGTGCTCGCCGGCAACCCGGCGAAGCATGACCTGGACATC 
AAGCCCACGGTCATCAGTCATCGCCTGCACTTCCCCGAGGGCGGCAGCCTGGCCGCGCTGACCGCGCACCAG 
GCTTGCCACCTGCCGCTGGAGACTTTCACCCGTCATCGCCAGCCGCGCGGCTGGGAACAACTGGAGCAGTGC 
GGCTATCCGGTGCAGCGGCTGGTCGCCCTCTACCTGGCGGCGCGGCTGTCGTGGAACCAGGTCGACCAGGTG 
ATCCGCAACGCCCTGGCCAGCCCCGGCAGCGGCGGCGACCTGGGCGAAGCGATCCGCGAGCAGCCGGAGCAG 
GCCCGTCTGGCCCTGACCCTGGCCGCCGCCGAGAGCGAGCGCTTCGTCCGGCAGGGCACCGGCAACGACGAG 
GCCAGCGCCGACGTGGTGAGCCTGACCTGCCCGGTCGCCGCCGGTGAATGCGCGGGCCCGGCGGACAGCGGC 
GACGCCCTGCTGGAGCGCAACTATCCCACTGGCGCGGAGTTCCTCGGCGACGGCGGCGACGTCAGCTTCAGC 
ACCCGCGGCACGCAGAACTGGACGGTGGAGCGGCTGCTCCAGGCGCACCGCCAACTGGAGGAGCGCGGCTAT 
GTGTTCGTCGGCTACCACGGCACCTTCCTCGAAGCGGCGCAAAGCATCGTCTTCGGCGGGGTGCGCGCGCGC 
AGCCAGGACCTCGACGCGATCTGGCGCGGTTTCTATATCGCCGGCGATCCGGCGCTGGCCTACGGCTACGCC 
CAGGACCAGGAACCCGACGCGCGCGGCCGGATCCGCAACGGTGCCCTGCTGCGGGTCTATGTGCCGCGCTCG 
AGTCTGCCGGGCTTCTACCGCACCGGCCTGACCCTGGCCGCGCCGGAGGCGGCGGGCGAGGTCGAACGGCTG 
ATCGGCCATCCGCTGCCGCTGCGCCTGGACGCCATCACCGGCCCCGAGGAGGAAGGCGGGCGCCTGGAGACC 
ATTCTCGGCTGGCCGCTGGCCGAGCGCACCGTGGTGATTCCCTCGGCGATCCCCACCGACCCGCGCAACGTC 
GGCGGCGACCTCGACCCGTCCAGCATCCCCGACCAGGAACAGGCGATCAGCGCCCTGCCGGACTACGCCAGC 
CAGCCCGGCAAACCGTCGCGCGAGGACCTGAAGTAG