ViewGene

Locus Name:
GeneID:
Location:

GeneID:3953
TrivialName: PA14_01710
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_01710
PAO1 Ortholog Locus:PA0139
Sequence Length:564
Protein Length:187
Start: 156164
Stop: 156727
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG03529.1|AE004452_1 (AE004452) alkyl hydroperoxide reductase subunit C [Pseudomonas aeruginosa PAO1]
Identities = 187/187 (100%), Positives = 187/187 (100%)
Sequence:
ATGTCCCTGATCAACACTCAAGTCCAACCGTTCAAGGTCAACGCTTTCCACAACGGCAAGTTCATCGAGGTG
ACCGAGGAATCCCTGAAGGGCAAGTGGTCGGTCCTGATCTTCATGCCGGCTGCCTTCACCTTCAACTGCCCG
ACCGAGATCGAAGACGCCGCCAACAACTACGGCGAGTTCCAGAAAGCCGGTGCCGAGGTCTACATCGTGACC
ACCGACACCCACTTCTCGCACAAGGTCTGGCACGAAACCTCCCCGGCCGTCGGCAAGGCCCAGTTCCCGCTG
ATCGGCGACCCGACCCACCAGCTGACCAACGCCTTCGGCGTGCACATCCCGGAAGAAGGCCTGGCCCTGCGC
GGTACCTTCGTGATCAACCCGGAAGGCGTGATCAAGACCGTCGAGATCCACTCCAACGAGATCGCCCGTGAC
GTCGGCGAGACCGTGCGCAAGCTGAAGGCCGCCCAGTACACCGCCGCCCACCCGGGCGAAGTCTGCCCGGCC
AAGTGGAAGGAAGGCGAGAAGACCCTCGCTCCGTCCCTGGACCTGGTCGGCAAGATCTAA
Translation:
MSLINTQVQPFKVNAFHNGKFIEVTEESLKGKWSVLIFMPAAFTFNCPTEIEDAANNYGEFQKAGAEVYIVT
TDTHFSHKVWHETSPAVGKAQFPLIGDPTHQLTNAFGVHIPEEGLALRGTFVINPEGVIKTVEIHSNEIARD
VGETVRKLKAAQYTAAHPGEVCPAKWKEGEKTLAPSLDLVGKI*
AnnotationID:3960GeneID:3953
AnnotatorUID: diggins
Modification Date/Time: 2005-03-23 06:06:15
Gene Name:ahpC
Confidence Code:2
GeneProduct:alkyl hydroperoxide reductase subunit C
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(1) Adaptation, protection
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0450,pfam00578
Secondary Functional Category(ies):posttranslational modification, protein turnover, chaperones
EC Number:1.6.4.-
Status:ACTIVE
Pathway:
Homology:
>emb|CAD17396.1| (AL646077) PROBABLE ALKYL HYDROPEROXIDE REDUCTASE (SUBUNIT C)
           OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]
          Length = 187

 Score =  346 bits (888), Expect = 4e-95
 Identities = 163/187 (87%), Positives = 175/187 (93%)

>gb|AAM35795.1| (AE011722) alkyl hydroperoxide reductase subunit C [Xanthomonas
           axonopodis pv. citri str. 306]
          Length = 187

 Score =  340 bits (873), Expect = 2e-93
 Identities = 163/187 (87%), Positives = 173/187 (92%)

>gb|AAN68051.1|AE016437_8 (AE016783) alkyl hydroperoxide reductase, C subunit [Pseudomonas
           putida KT2440]
          Length = 187

 Score =  265 bits (677), Expect = 1e-70
 Identities = 122/187 (65%), Positives = 147/187 (78%)

Structural Features:
COG0450, AhpC, Peroxiredoxin 
[Posttranslational modification, protein turnover, chaperones]
CD-Length = 194 residues,  96.4% aligned
Score =  240 bits (614), Expect = 8e-65
Identities = 94/188 (50%), Positives = 118/188 (62%), Gaps = 5/188 (2%)

pfam00578, AhpC-TSA, AhpC/TSA family. 
This family contains proteins related to alkyl hydroperoxide reductase (AhpC) 
and thiol specific antioxidant (TSA).
CD-Length = 145 residues, 100.0% aligned
Score =  142 bits (359), Expect = 3e-35
Identities = 56/147 (38%), Positives = 83/147 (56%), Gaps = 2/147 (1%)

Genomic Context:
Comment:
ReferenceID:7908
Author/Investigator(s): GenNotator
Title:
PubMed:
MedLine:
Source:
Reference Type:BLASTP
Data:
URL:
ReferenceID:25051
Author/Investigator(s): GenNotator
Title: CDD Search
PubMed:
MedLine:
Source:
Reference Type:RPSBLAST
Data:
URL:
ReferenceID:33518
Author/Investigator(s):
Title: CDD Search
PubMed:
MedLine:
Source:
Reference Type:Misc (text/plain)
Data:3953_cdd.html
URL:
ReferenceID:35496
Author/Investigator(s): Antelmann H, Engelmann S, Schmid R, Hecker M.
Title: General and oxidative stress responses in Bacillus subtilis: cloning, expression, and mutation of the alkyl hydroperoxide reductase operon.
PubMed: 8932314
MedLine:
Source:
J Bacteriol. 1996 Nov;178(22):6571-8.
Reference Type:Journal
Data:
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8932314
ReferenceID:35499
Author/Investigator(s): Rocha ER, Smith CJ.
Title: Role of the alkyl hydroperoxide reductase (ahpCF) gene in oxidative stress defense of the obligate Anaerobe bacteroides fragilis.
PubMed: 10482511
MedLine:
Source:
J Bacteriol. 1999 Sep;181(18):5701-10.
Reference Type:Journal
Data:
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10482511
Homologs By Global Alignment
Gene ID:3953

Identity:

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
HomologID Accession Description Length PctIdentity PctSimilarity Gaps Score
6191 PA0139_tr translation of PA0139 187 99.99 99.99 0 988.0
171608 gb|AAG03529.1|AE004452_1 (AE004452) alkyl hydroperoxide reductase subunit C [Pseudomonas aeruginosa PAO1] 187 99.99 99.99 0 988.0
171609 emb|CAD17396.1| (AL646077) PROBABLE ALKYL HYDROPEROXIDE REDUCTASE (SUBUNIT C) OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum] 187 87.16 93.58 0 888.0
171610 gb|AAM35795.1| (AE011722) alkyl hydroperoxide reductase subunit C [Xanthomonas axonopodis pv. citri str. 306] 187 87.16 92.51 0 873.0
171611 gb|AAC45425.1| (U94336) alkyl hydroperoxide reductase subunit C [Xanthomonas campestris] 187 87.16 92.51 0 873.0
GC ORFID: 46955How Found: BLASTX
GC_TrimmedSeqID: 69Blast Result ID
Subject Sequence Name: t_PA0139Glimmer Score:
Start: 5957503Stop: 5958066
Length: 564
Start Codon: ATGTruncated Start:
Stop Codon: TAATruncated Stop:
Homolog: t_PA0139 translation of PA0139Homolog Bit Score 385.0
Other Homologs: psyr_15may02_Scaffold7_revised_gene7275 (ORF: BLASTX 260.0), t_PA0139 (ORF: GLIMMER)
GC ORF Sequence
ATGTCCCTGATCAACACTCAAGTCCAACCGTTCAAGGTCAACGCTTTCCACAACGGCAAGTTCATCGAGGTG
ACCGAGGAATCCCTGAAGGGCAAGTGGTCGGTCCTGATCTTCATGCCGGCTGCCTTCACCTTCAACTGCCCG
ACCGAGATCGAAGACGCCGCCAACAACTACGGCGAGTTCCAGAAAGCCGGTGCCGAGGTCTACATCGTGACC
ACCGACACCCACTTCTCGCACAAGGTCTGGCACGAAACCTCCCCGGCCGTCGGCAAGGCCCAGTTCCCGCTG
ATCGGCGACCCGACCCACCAGCTGACCAACGCCTTCGGCGTGCACATCCCGGAAGAAGGCCTGGCCCTGCGC
GGTACCTTCGTGATCAACCCGGAAGGCGTGATCAAGACCGTCGAGATCCACTCCAACGAGATCGCCCGTGAC
GTCGGCGAGACCGTGCGCAAGCTGAAGGCCGCCCAGTACACCGCCGCCCACCCGGGCGAAGTCTGCCCGGCC
AAGTGGAAGGAAGGCGAGAAGACCCTCGCTCCGTCCCTGGACCTGGTCGGCAAGATCTAA