ViewGene
Locus Name:
GeneID:
Location:

GeneID:3847
TrivialName: PA14_70440
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_70440
PAO1 Ortholog Locus:PA5336
Sequence Length:612
Protein Length:203
Start: 6278118
Stop: 6278729
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08721.1|AE004946_5 (AE004946) guanylate kinase [Pseudomonas aeruginosa PAO1]
Identities = 203/203 (100%), Positives = 203/203 (100%)
Sequence:
ATGTCCGGCACCCTGTACATCGTTTCCGCTCCCTCCGGCGCCGGCAAGACCAGCCTGGTGAAGGCCCTGCTC
GACGCCGCCCCCGAGGTCCGCGTGTCCGTCTCCCATACCACCCGCGGCATGCGTCCGGGCGAGGTGGACGGG
GTCAACTACCACTTCACCAGCCGCGAGGAATTCCTCGCCATGCTCGAACGCAACGAGTTCCTCGAGCACGCC
GAAGTCTTCGGCAACCTCTACGGCACCTCGCAGCGCTGGGTCGAGAAAACCCTCGCCGAAGGCCTCGACCTG
ATCCTCGAGATCGACTGGCAGGGCGCCCAGCAGGTGCGCCGGCTGATGCCCGAGGCCCAATCGATCTTCATC
CTCCCGCCGAGCCAGGAAGCCCTGCGCCAGCGCCTGACCAACCGCGGCCAGGACAGCGACGAGGTGATCGAG
CGGCGCATGCGCGAAGCCGTCAGCGAAATGAGCCACTACGTGGAGTACGATCACCTGGTGATCAACGACGAT
TTCGCCCACGCCCTGGACGACCTCAAGGCGATCTTCCGCGCCCGCCAGTTGCGCCAGGACGCCCAGCAGCAA
CGCCACGCCGAACTGCTCGGTCGTCTGCTCGCCTAA
Translation:
MSGTLYIVSAPSGAGKTSLVKALLDAAPEVRVSVSHTTRGMRPGEVDGVNYHFTSREEFLAMLERNEFLEHA
EVFGNLYGTSQRWVEKTLAEGLDLILEIDWQGAQQVRRLMPEAQSIFILPPSQEALRQRLTNRGQDSDEVIE
RRMREAVSEMSHYVEYDHLVINDDFAHALDDLKAIFRARQLRQDAQQQRHAELLGRLLA*
AnnotationID:3854GeneID:3847
AnnotatorUID: diggins
Modification Date/Time: 2005-04-26 19:07:38
Gene Name:gmk
Confidence Code:2
GeneProduct:guanylate kinase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0194,cd00071,smart00072,pfam00625
Secondary Functional Category(ies):
EC Number:2.7.4.8
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO53629.1| (AE016856) guanylate kinase [Pseudomonas syringae pv. tomato str.
           DC3000]
          Length = 214

 Score =  294 bits (752), Expect = 3e-79
 Identities = 149/211 (70%), Positives = 177/211 (83%), Gaps = 8/211 (3%)

>gb|AAN70861.1|AE016730_7 (AE016794) guanylate kinase [Pseudomonas putida KT2440]
          Length = 206

 Score =  274 bits (700), Expect = 3e-73
 Identities = 137/201 (68%), Positives = 163/201 (81%)

>gb|AAF95848.1| (AE004336) guanylate kinase [Vibrio cholerae]
          Length = 229

 Score =  261 bits (666), Expect = 2e-69
 Identities = 128/203 (63%), Positives = 162/203 (79%), Gaps = 2/203 (0%)







 
Structural Features:
COG0194, Gmk, Guanylate kinase [Nucleotide transport and metabolism]
CD-Length = 191 residues,  97.9% aligned
Score =  267 bits (685), Expect = 6e-73
Identities = 106/188 (56%), Positives = 138/188 (73%), Gaps = 1/188 (0%)

cd00071, GuKc, Guanylate kinase homologues. 
CD-Length = 182 residues,  98.9% aligned
Score =  206 bits (526), Expect = 1e-54
Identities = 91/180 (50%), Positives = 122/180 (67%), Gaps = 2/180 (1%)

smart00072, GuKc, Guanylate kinase homologues
CD-Length = 184 residues,  99.5% aligned
Score =  165 bits (420), Expect = 3e-42
Identities = 75/183 (40%), Positives = 104/183 (56%), Gaps = 1/183 (0%)

pfam00625, Guanylate_kin, Guanylate kinase.
CD-Length = 105 residues, 100.0% aligned
Score =  115 bits (289), Expect = 4e-27
Identities = 47/105 (44%), Positives = 63/105 (60%)






   
Genomic Context:






   
Comment:


















    ReferenceID:7697




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24839




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34771




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3847_cdd.html


    		




 
URL:

















    ReferenceID:35692




  
Author/Investigator(s):
        Gentry D, Bengra C, Ikehara K, Cashel M.





  
Title:
        Guanylate kinase of Escherichia coli K-12.




  
PubMed:
        8390989


MedLine:
        




    
Source:
J Biol Chem. 1993 Jul 5;268(19):14316-21.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8390989









           
Homologs By Global Alignment 

           

       



     
Gene ID:3847
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6072
                           PA5336_tr
                           translation of PA5336
                           203
                           99.99
                           99.99
                           0
                           1028.0
     

     
     
169477
                           gb|AAG08721.1|AE004946_5
                           (AE004946) guanylate kinase [Pseudomonas aeruginosa PAO1]
                           203
                           99.99
                           99.99
                           0
                           1028.0
     

     
     
169478
                           gb|AAO53629.1|
                           (AE016856) guanylate kinase [Pseudomonas syringae pv. tomato str. DC3000]
                           214
                           69.62
                           82.71
                           11
                           757.0
     

     
     
169479
                           gb|AAN70861.1|AE016730_7
                           (AE016794) guanylate kinase [Pseudomonas putida KT2440]
                           206
                           66.50
                           79.12
                           3
                           699.0
     

     
     
169490
                           gb|AAA62001.1|
                           (L10328) 5'guanylate kinase [Escherichia coli]
                           207
                           60.86
                           76.32
                           4
                           645.0
     

     






      

          
GC ORFID: 46849How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA5336Glimmer Score: 

          
Start: 5541807Stop: 5542418

          
Length: 612


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA5336 translation of PA5336Homolog Bit Score 400.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene3940 (ORF: BLASTX 294.0), t_PA5336 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTCCGGCACCCTGTACATCGTTTCCGCTCCCTCCGGCGCCGGCAAGACCAGCCTGGTGAAGGCCCTGCTC 
GACGCCGCCCCCGAGGTCCGCGTGTCCGTCTCCCATACCACCCGCGGCATGCGTCCGGGCGAGGTGGACGGG 
GTCAACTACCACTTCACCAGCCGCGAGGAATTCCTCGCCATGCTCGAACGCAACGAGTTCCTCGAGCACGCC 
GAAGTCTTCGGCAACCTCTACGGCACCTCGCAGCGCTGGGTCGAGAAAACCCTCGCCGAAGGCCTCGACCTG 
ATCCTCGAGATCGACTGGCAGGGCGCCCAGCAGGTGCGCCGGCTGATGCCCGAGGCCCAATCGATCTTCATC 
CTCCCGCCGAGCCAGGAAGCCCTGCGCCAGCGCCTGACCAACCGCGGCCAGGACAGCGACGAGGTGATCGAG 
CGGCGCATGCGCGAAGCCGTCAGCGAAATGAGCCACTACGTGGAGTACGATCACCTGGTGATCAACGACGAT 
TTCGCCCACGCCCTGGACGACCTCAAGGCGATCTTCCGCGCCCGCCAGTTGCGCCAGGACGCCCAGCAGCAA 
CGCCACGCCGAACTGCTCGGTCGTCTGCTCGCCTAA