ViewGene
Locus Name:
GeneID:
Location:

GeneID:3818
TrivialName: PA14_25740
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_25740
PAO1 Ortholog Locus:PA2962
Sequence Length:633
Protein Length:210
Start: 2247669
Stop: 2248301
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06350.1|AE004722_6 (AE004722) thymidylate kinase [Pseudomonas aeruginosa PAO1]
Identities = 206/210 (98%), Positives = 207/210 (98%)
Sequence:
GTGACCGGCCTGTTCGTCACCCTGGAGGGCCCGGAAGGGGCCGGCAAGAGCACCAACCGCGACTACCTGGCC
GAGCGTCTGCGCGAGCGCGGCATCGAGGTGCAGTTGACCCGCGAGCCTGGCGGCACGCCTCTCGCCGAGCGC
ATCCGTGAGCTGCTGCTGGCGCCCGGCGACGAGCCGATGGCCGCCGATACCGAGCTGTTGCTGATGTTCGCC
GCGCGGGCCCAGCATATCGCCGGGGTCATCCGTCCGGCACTGGCGCGCGGGGCCGTGGTGCTCTGCGATCGC
TTCACCGATGCCACCTATGCCTACCAGGGCGGCGGGCGCGGCTTGCCGGAGGTGCGCATCGCCGCGCTGGAA
AGCTTCGTCCAGGGCGACCTGCGGCCCGACCTCACGCTGGTCTTCGACCTGCCGGTGGAAATCGGCCTGGCG
CGGGCGGCGGCGCGTGGCCGGCTCGACCGTTTCGAGCAGGAGGACCGACGCTTCTTCGAGGCCGTGCGTCAG
ACCTACCTGCAGCGCGCCGCGCAGGCCCCGGAGCGTTACCAGGTGCTCGACGCCGGGTTGCCGCTGACCGAG
GTGCAGGCTGGCCTGGATCGGCTGCTGCCGAATCTGCTGGAGCGTCTGAATGGCTGA
Translation:
MTGLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPGDEPMAADTELLLMFA
ARAQHIAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEVRIAALESFVQGDLRPDLTLVFDLPVEIGLA
RAAARGRLDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLDAGLPLTEVQAGLDRLLPNLLERLNG*
AnnotationID:3825GeneID:3818
AnnotatorUID: diggins
Modification Date/Time: 2005-04-10 15:03:27
Gene Name:tmk
Confidence Code:2
GeneProduct:thymidylate kinase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0125,pfam02223
Secondary Functional Category(ies):
EC Number:2.7.4.9
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO57295.1| (AE016869) thymidylate kinase [Pseudomonas syringae pv. tomato str.
           DC3000]
          Length = 210

 Score =  328 bits (840), Expect = 2e-89
 Identities = 167/210 (79%), Positives = 182/210 (86%)

>emb|CAE33130.1| (BX640445) thymidylate kinase [Bordetella bronchiseptica]
          Length = 208

 Score =  211 bits (536), Expect = 3e-54
 Identities = 107/196 (54%), Positives = 142/196 (72%), Gaps = 3/196 (1%)

>emb|CAE36861.1| (BX640427) thymidylate kinase [Bordetella parapertussis]
          Length = 208

 Score =  211 bits (536), Expect = 3e-54
 Identities = 107/196 (54%), Positives = 142/196 (72%), Gaps = 3/196 (1%)








 
Structural Features:
COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism]
CD-Length = 208 residues,  98.6% aligned
Score =  223 bits (571), Expect = 8e-60
Identities = 109/208 (52%), Positives = 139/208 (66%), Gaps = 2/208 (0%)

pfam02223, Thymidylate_kin, Thymidylate kinase.
CD-Length = 186 residues,  98.9% aligned
Score =  159 bits (403), Expect = 3e-40
Identities = 78/188 (41%), Positives = 109/188 (57%), Gaps = 4/188 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:14935




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24781




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36086




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3818_cdd.html


    		




 
URL:

















    ReferenceID:36433




  
Author/Investigator(s):
        Reynes JP, Tiraby M, Baron M, Drocourt D, Tiraby G.





  
Title:
        Escherichia coli thymidylate kinase: molecular cloning, nucleotide sequence, and genetic organization of the corresponding tmk locus.




  
PubMed:
        8631667


MedLine:
        




    
Source:
J Bacteriol. 1996 May;178(10):2804-12.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8631667









           
Homologs By Global Alignment 

           

       



     
Gene ID:3818
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6039
                           PA2962_tr
                           translation of PA2962
                           210
                           98.09
                           98.57
                           0
                           1037.0
     

     
     
168138
                           gb|AAG06350.1|AE004722_6
                           (AE004722) thymidylate kinase [Pseudomonas aeruginosa PAO1]
                           210
                           97.61
                           98.57
                           0
                           1034.0
     

     
     
168139
                           gb|AAO57295.1|
                           (AE016869) thymidylate kinase [Pseudomonas syringae pv. tomato str. DC3000]
                           210
                           79.04
                           86.66
                           0
                           836.0
     

     
     
168143
                           gb|AAQ61385.1|
                           (AE016923) dTMP kinase [Chromobacterium violaceum ATCC 12472]
                           215
                           52.09
                           65.11
                           8
                           525.0
     

     
     
168142
                           emb|CAE36861.1|
                           (BX640427) thymidylate kinase [Bordetella parapertussis]
                           212
                           50.94
                           68.86
                           6
                           533.0
     

     






      

          
GC ORFID: 46820How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2962Glimmer Score: 

          
Start: 2706256Stop: 2705624

          
Length: 633


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2962 translation of PA2962Homolog Bit Score 404.0

          
Other Homologs:  psyr_15may02_Scaffold16_revised_gene2613 (ORF: BLASTX 326.0), t_PA2962 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGACCGGCCTGTTCGTCACCCTGGAGGGCCCGGAAGGGGCCGGCAAGAGCACCAACCGCGACTACCTGGCC 
GAGCGTCTGCGCGAGCGCGGCATCGAGGTGCAGTTGACCCGCGAGCCTGGCGGCACGCCTCTCGCCGAGCGC 
ATCCGTGAGCTGCTGCTGGCGCCCGGCGACGAGCCGATGGCCGCCGATACCGAGCTGTTGCTGATGTTCGCC 
GCGCGGGCCCAGCATATCGCCGGGGTCATCCGTCCGGCACTGGCGCGCGGGGCCGTGGTGCTCTGCGATCGC 
TTCACCGATGCCACCTATGCCTACCAGGGCGGCGGGCGCGGCTTGCCGGAGGTGCGCATCGCCGCGCTGGAA 
AGCTTCGTCCAGGGCGACCTGCGGCCCGACCTCACGCTGGTCTTCGACCTGCCGGTGGAAATCGGCCTGGCG 
CGGGCGGCGGCGCGTGGCCGGCTCGACCGTTTCGAGCAGGAGGACCGACGCTTCTTCGAGGCCGTGCGTCAG 
ACCTACCTGCAGCGCGCCGCGCAGGCCCCGGAGCGTTACCAGGTGCTCGACGCCGGGTTGCCGCTGACCGAG 
GTGCAGGCTGGCCTGGATCGGCTGCTGCCGAATCTGCTGGAGCGTCTGAATGGCTGA