ViewGene
Locus Name:
GeneID:
Location:

GeneID:3809
TrivialName: PA14_57800
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_57800
PAO1 Ortholog Locus:PA4449
Sequence Length:636
Protein Length:211
Start: 5147778
Stop: 5147143
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07837.1|AE004859_6 (AE004859) ATP-phosphoribosyltransferase [Pseudomonas aeruginosa PAO1]
Identities = 210/211 (99%), Positives = 210/211 (99%)
Sequence:
ATGCTGACCATCGCCTTGTCCAAGGGCCGGATTCTCGACGATACCCTGCCGCTGCTCGCAGCGGCGGGCATC
GTGCCGTCGGAGAACCCGGACAAGAGCCGCAAGCTGATCATCCCGACGTCCCTGCCCGATGTGCGCCTGCTC
ATCGTGCGCGCCACCGACGTGCCGACCTATGTCGAGCATGGCGCCGCCGATCTCGGCGTGGCCGGCAAGGAC
GTGCTGATGGAGTACGGCGGCCAGGGACTCTACGAACCGCTGGACCTGCGTATCGCCAACTGCAAGCTGATG
ACCGCCGGCGCCATTGGCGCGCCTGAACCCAAGGGACGCCTGCGGGTGGCCACCAAGTTCGTCAATGTCGCC
AAGCGCTACTACGCCGAGCAGGGCCGCCAGGTCGACGTGATCAAGCTGTACGGCTCGATGGAGCTGGCGCCG
CTGGTCGGTCTCGCCGACAAGATCATCGACGTCGTGGATACCGGCAACACCCTGCGCGCCAACGGCCTGGAG
CCCCAGGAACTGATCGCCACGATCAGCTCGCGCCTGGTGGTCAACAAGGCCTCGATGAAGATGCAGCACGGT
CGCATCCAGTCGCTGATCGATACCCTGCGCGACGCCGTCGAGGCGCGACACCGTCACTGA
Translation:
MLTIALSKGRILDDTLPLLAAAGIVPSENPDKSRKLIIPTSLPDVRLLIVRATDVPTYVEHGAADLGVAGKD
VLMEYGGQGLYEPLDLRIANCKLMTAGAIGAPEPKGRLRVATKFVNVAKRYYAEQGRQVDVIKLYGSMELAP
LVGLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHGRIQSLIDTLRDAVEARHRH*
AnnotationID:3816GeneID:3809
AnnotatorUID: diggins
Modification Date/Time: 2005-05-03 06:06:51
Gene Name:hisG
Confidence Code:2
GeneProduct: ATP-phosphoribosyltransferase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0040,pfam01634
Secondary Functional Category(ies):
EC Number:2.4.2.17
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN66590.1|AE016287_1 (AE016777) ATP phosphoribosyltransferase [Pseudomonas putida
           KT2440]
          Length = 211

 Score =  378 bits (971), Expect = e-104
 Identities = 194/210 (92%), Positives = 201/210 (95%)

>gb|AAO57888.1| (AE016872) ATP phosphoribosyltransferase [Pseudomonas syringae pv.
           tomato str. DC3000]
          Length = 211

 Score =  377 bits (968), Expect = e-104
 Identities = 194/210 (92%), Positives = 202/210 (96%)








 
Structural Features:
COG0040, HisG, ATP phosphoribosyltransferase 
[Amino acid transport and metabolism]
CD-Length = 290 residues, only  75.2% aligned
Score =  221 bits (564), Expect = 1e-58
Identities = 107/220 (48%), Positives = 142/220 (64%), Gaps = 11/220 (5%)

pfam01634, HisG, ATP phosphoribosyltransferase.
CD-Length = 162 residues, 100.0% aligned
Score =  140 bits (355), Expect = 2e-34
Identities = 65/162 (40%), Positives = 97/162 (59%), Gaps = 6/162 (3%)






   
Genomic Context:






   
Comment:


















    ReferenceID:7621




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24763




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31487




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3809_cdd.html


    		




 
URL:

















    ReferenceID:32834




  
Author/Investigator(s):
        Thoma R, Schwander M, Liebl W, Kirschner K, Sterner R.





  
Title:
        A histidine gene cluster of the hyperthermophile Thermotoga maritima: sequence analysis and evolutionary significance.




  
PubMed:
        9827326


MedLine:
        




    
Source:
Extremophiles. 1998 Nov;2(4):379-89.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9827326

















    ReferenceID:32835




  
Author/Investigator(s):
        Hoppe I, Johnston HM, Biek D, Roth JR.





  
Title:
        A refined map of the hisG gene of Salmonella typhimurium.




  
PubMed:
        387517


MedLine:
        




    
Source:
Genetics. 1979 May;92(1):17-26.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=387517

















    ReferenceID:32836




  
Author/Investigator(s):
        Scott JF, Roth JR, Artz SW.





  
Title:
        Regulation of histidine operon does not require hisG enzyme.

Regulation of histidine operon does not require hisG enzyme.




  
PubMed:
        1108009


MedLine:
        




    
Source:
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5021-5.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1108009









           
Homologs By Global Alignment 

           

       



     
Gene ID:3809
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6030
                           PA4449_tr
                           translation of PA4449
                           211
                           99.52
                           99.52
                           0
                           1044.0
     

     
     
168051
                           gb|AAG07837.1|AE004859_6
                           (AE004859) ATP-phosphoribosyltransferase [Pseudomonas aeruginosa PAO1]
                           211
                           99.52
                           99.52
                           0
                           1044.0
     

     
     
168052
                           gb|AAN66590.1|AE016287_1
                           (AE016777) ATP phosphoribosyltransferase [Pseudomonas putida KT2440]
                           211
                           91.94
                           95.26
                           0
                           969.0
     

     
     
168053
                           gb|AAO57888.1|
                           (AE016872) ATP phosphoribosyltransferase [Pseudomonas syringae pv. tomato str. DC3000]
                           211
                           91.94
                           95.73
                           0
                           965.0
     

     
     
168054
                           gb|AAQ58286.1|
                           (AE016912) ATP phosphoribosyltransferase [Chromobacterium violaceum ATCC 12472]
                           217
                           60.36
                           76.95
                           10
                           646.0
     

     






      

          
GC ORFID: 46811How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4449Glimmer Score: 

          
Start: 4411457Stop: 4410822

          
Length: 636


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4449 translation of PA4449Homolog Bit Score 406.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5526 (ORF: BLASTX 377.0), t_PA4449 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCTGACCATCGCCTTGTCCAAGGGCCGGATTCTCGACGATACCCTGCCGCTGCTCGCAGCGGCGGGCATC 
GTGCCGTCGGAGAACCCGGACAAGAGCCGCAAGCTGATCATCCCGACGTCCCTGCCCGATGTGCGCCTGCTC 
ATCGTGCGCGCCACCGACGTGCCGACCTATGTCGAGCATGGCGCCGCCGATCTCGGCGTGGCCGGCAAGGAC 
GTGCTGATGGAGTACGGCGGCCAGGGACTCTACGAACCGCTGGACCTGCGTATCGCCAACTGCAAGCTGATG 
ACCGCCGGCGCCATTGGCGCGCCTGAACCCAAGGGACGCCTGCGGGTGGCCACCAAGTTCGTCAATGTCGCC 
AAGCGCTACTACGCCGAGCAGGGCCGCCAGGTCGACGTGATCAAGCTGTACGGCTCGATGGAGCTGGCGCCG 
CTGGTCGGTCTCGCCGACAAGATCATCGACGTCGTGGATACCGGCAACACCCTGCGCGCCAACGGCCTGGAG 
CCCCAGGAACTGATCGCCACGATCAGCTCGCGCCTGGTGGTCAACAAGGCCTCGATGAAGATGCAGCACGGT 
CGCATCCAGTCGCTGATCGATACCCTGCGCGACGCCGTCGAGGCGCGACACCGTCACTGA