ViewGene
Locus Name:
GeneID:
Location:

GeneID:3792
TrivialName: PA14_11510
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_11510
PAO1 Ortholog Locus:PA4047
Sequence Length:618
Protein Length:205
Start: 995865
Stop: 996482
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07434.1|AE004821_7 (AE004821) GTP cyclohydrolase II [Pseudomonas aeruginosa PAO1]
Identities = 204/205 (99%), Positives = 205/205 (100%)
Sequence:
GTGTCCGTCGTGTTCGTCGCCGCCTCCAAACTGCCGACTCCCTTCGGCGAATTCACCATGCATGGTTTCCTC
GACGAGGAGAGCGGCAAGGAACATGTAGCCCTGAGCATGGGCGACATCGCCGATGGCGCGCCGGTGCTTGGT
CGCCTGCATTCCGAATGCCTGACCGGCGACGCGCTGTTCAGCCTGCGCTGCGATTGCGGTTTCCAGTTGGAA
GGCGCGCTTGCCGCCATCGCCGAGGAGGGCCGCGGCGTGCTCCTCTACCTGCGCCAGGAAGGTCGCGGCATC
GGCCTGCTGAACAAGATCCGTGCCTATGAATTGCAGGATGGCGGTGCCGACACCGTCGAGGCGAACCTGCAA
CTGGGTTTTGGCGCCGACCAGCGCGACTACGCCATGTGCCAGCCGATGCTCGCGCACCTGGGCGTCTCCTCC
CTGCGCCTGATGACCAACAATCCGCGCAAGGTCAAGGCGCTGGAAAGCTACGCCATCACCGTGGCGGAGCGC
GTGCCGCTGCAAAGGGGCCTGAACAAGCACAACAGGCGCTACCTGGCGACCAAGGCCGGCAAGCTCGGGCAC
ATGCTCGGCAGCCTGCACCAGGGCGAGGCGGAAACCACGTGA
Translation:
MSVVFVAASKLPTPFGEFTMHGFLDEESGKEHVALSMGDIADGAPVLGRLHSECLTGDALFSLRCDCGFQLE
GALAAIAEEGRGVLLYLRQEGRGIGLLNKIRAYELQDGGADTVEANLQLGFGADQRDYAMCQPMLAHLGVSS
LRLMTNNPRKVKALESYAITVAERVPLQRGLNKHNRRYLATKAGKLGHMLGSLHQGEAETT*
AnnotationID:3799GeneID:3792
AnnotatorUID: urbach
Modification Date/Time: 2004-10-06 15:03:19
Gene Name:ribA
Confidence Code:2
GeneProduct:GTP cyclohydrolase II
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(4) Biosynthesis of cofactors, prosthetic groups and carriers
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0807,pfam00925,KOG1284
Secondary Functional Category(ies):
EC Number:3.5.4.25
Status:ACTIVE
Pathway:
biosynthesis of riboflavin
Homology:
dbj|BAA14831.1| (D90766) GTP cyclohydrolase II (EC 3.5.4.25) [Escherichia coli]
Length: 205
PctIdentity: 60.00
PctSimilarity: 71.21
Gaps: 9
BitScore: 625.0
Structural Features:
gnl|CDD|10675 COG0807, RibA, GTP cyclohydrolase II [Coenzyme metabolism]
Length = 193
Score =  266 bits (682), Expect = 2e-72
Identities = 122/194 (62%), Positives = 141/194 (72%), Gaps = 1/194 (0%)
Genomic Context:






   
Comment:


















    ReferenceID:14923




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24729




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34651




  
Author/Investigator(s):
        Richter G, Ritz H, Katzenmeier G, Volk R, Kohnle A, Lottspeich F, Allendorf D, Bacher A.





  
Title:
        Biosynthesis of riboflavin: cloning, sequencing, mapping, and expression of the gene coding for GTP cyclohydrolase II in Escherichia coli.




  
PubMed:
        8320220


MedLine:
        




    
Source:
J Bacteriol. 1993 Jul;175(13):4045-51.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8320220&itool=iconpmc









           
Homologs By Global Alignment 

           

       



     
Gene ID:3792
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
6013
                           PA4047_tr
                           translation of PA4047
                           205
                           99.51
                           99.99
                           0
                           1049.0
     

     
     
167620
                           gb|AAG07434.1|AE004821_7
                           (AE004821) GTP cyclohydrolase II [Pseudomonas aeruginosa PAO1]
                           205
                           99.02
                           99.99
                           0
                           1046.0
     

     
     
167621
                           gb|AAN66149.1|AE016243_1
                           (AE016776) GTP cyclohydrolase II [Pseudomonas putida KT2440]
                           205
                           81.46
                           84.87
                           0
                           850.0
     

     
     
167622
                           gb|AAO54238.1|
                           (AE016858) GTP cyclohydrolase II [Pseudomonas syringae pv. tomato str. DC3000]
                           221
                           72.39
                           78.28
                           16
                           833.0
     

     
     
167624
                           gb|AAN55847.1|AE015721_10
                           (AE015721) GTP cyclohydrolase II [Shewanella oneidensis MR-1]
                           205
                           65.85
                           77.07
                           2
                           699.0
     

     






      

          
GC ORFID: 46794How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4047Glimmer Score: 

          
Start: 3958072Stop: 3957455

          
Length: 618


          
Start Codon: GTGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4047 translation of PA4047Homolog Bit Score 408.0

          
Other Homologs:  psyr_15may02_Scaffold4_revised_gene5268 (ORF: BLASTX 325.0), t_PA4047 (ORF: GLIMMER)

          
GC ORF Sequence

           
GTGTCCGTCGTGTTCGTCGCCGCCTCCAAACTGCCGACTCCCTTCGGCGAATTCACCATGCATGGTTTCCTC 
GACGAGGAGAGCGGCAAGGAACATGTAGCCCTGAGCATGGGCGACATCGCCGATGGCGCGCCGGTGCTTGGT 
CGCCTGCATTCCGAATGCCTGACCGGCGACGCGCTGTTCAGCCTGCGCTGCGATTGCGGTTTCCAGTTGGAA 
GGCGCGCTTGCCGCCATCGCCGAGGAGGGCCGCGGCGTGCTCCTCTACCTGCGCCAGGAAGGTCGCGGCATC 
GGCCTGCTGAACAAGATCCGTGCCTATGAATTGCAGGATGGCGGTGCCGACACCGTCGAGGCGAACCTGCAA 
CTGGGTTTTGGCGCCGACCAGCGCGACTACGCCATGTGCCAGCCGATGCTCGCGCACCTGGGCGTCTCCTCC 
CTGCGCCTGATGACCAACAATCCGCGCAAGGTCAAGGCGCTGGAAAGCTACGCCATCACCGTGGCGGAGCGC 
GTGCCGCTGCAAAGGGGCCTGAACAAGCACAACAGGCGCTACCTGGCGACCAAGGCCGGCAAGCTCGGGCAC 
ATGCTCGGCAGCCTGCACCAGGGCGAGGCGGAAACCACGTGA