ViewGene
Locus Name:
GeneID:
Location:

GeneID:3693
TrivialName: PA14_23620
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23620
PAO1 Ortholog Locus:PA3131
Sequence Length:648
Protein Length:215
Start: 2055247
Stop: 2055894
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06519.1|AE004737_5 (AE004737) probable aldolase [Pseudomonas aeruginosa PAO1]
Identities = 214/215 (99%), Positives = 214/215 (99%)
Sequence:
ATGACATTGCCGCTGGATCGGGTCCTGCTGCAGGCCAGCCCGGTATTGCCGGTGCTGGTGATCGAGGACGTG
GCGCTGGCGCCCGACCTGGCGCGCGCGTTGTATGCGGGCGGCGTCACGGTGTTGGAAGTGACGCTGCGCACG
CCGCAGGCGCTGGACGCGATCGCCGCCATCCATCGCGAGGTGCCCGAGGTCCTGCTGGGGGCGGGTACCCTG
ATCCACACCGAGCAGTTTCTCGAGGCACGCGACGCGGGCGCGCAGTTCGCCGTCAGCCCCGGATGCACGCCG
CGCCTTGCCGCCGCCGCGGAGGATGCCGGCCTGCCATACCTGCCCGGGGTGATGACGCCTTCGGAAGTGTTG
CTGGCGCTGGAGTACGGTTATCGCTCGCTGAAGCTGTTCCCGGCCGATGGCACTGCCAGCGTGAAAATGCTG
AAAAGCCTGAAGGGGCCGTTCACCGGCATCCGCTTCTGCCCGACCGGCGGCGTCAACCTGGACAACCTGCTG
AATTTCCTCCGCCTGCCCAATGTCGCCTGTGTCGGCGGCACCTGGCTGGCGCCGCCGAGCTTGATCCGGGCG
CGGGCCTGGGATCAGATCACACAACTGGCCAGGGAAGCGCGCGAACTGGCCGGCAGCCTGGAGCAGCATTGA
Translation:
MTLPLDRVLLQASPVLPVLVIEDVALAPDLARALYAGGVTVLEVTLRTPQALDAIAAIHREVPEVLLGAGTL
IHTEQFLEARDAGAQFAVSPGCTPRLAAAAEDAGLPYLPGVMTPSEVLLALEYGYRSLKLFPADGTASVKML
KSLKGPFTGIRFCPTGGVNLDNLLNFLRLPNVACVGGTWLAPPSLIRARAWDQITQLAREARELAGSLEQH*
AnnotationID:3701GeneID:3693
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 08:08:57
Gene Name:kdgA
Confidence Code:3
GeneProduct:putative 2-keto-3-deoxygluconate 6-phosphate aldolase
Cell Localization:()
Synonyms:eda
Cell Localization Confidence Code:5
MolecularFunction:putative 2-dehydro-3-deoxy-phosphogluconate aldolase
Functional Category:(5) Carbon compound catabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam01081,COG0800
Secondary Functional Category(ies):central intermediary metabolism
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>emb|CAB84839.1| (AL162756) 2-keto-4-hydroxyglutarate aldolase [Neisseria
           meningitidis Z2491]
          Length = 212

 Score =  210 bits (535), Expect = 4e-54
 Identities = 102/202 (50%), Positives = 137/202 (67%)

>gb|AAP17241.1| (AE016984) 2-keto-3-deoxygluconate 6-phosphate aldolase and
           2-keto-4-hydroxyglutarate aldolase [Shigella flexneri 2a
           str. 2457T]
          Length = 213

 Score =  204 bits (518), Expect = 4e-52
 Identities = 97/199 (48%), Positives = 141/199 (70%)

>gb|AAC74920.1| (AE000279) 2-keto-3-deoxygluconate 6-phosphate aldolase and
           2-keto-4-hydroxyglutarate aldolase [Escherichia coli
           K12]
          Length = 213

 Score =  204 bits (518), Expect = 4e-52
 Identities = 97/199 (48%), Positives = 141/199 (70%)






 
Structural Features:
pfam01081, Aldolase, KDPG and KHG aldolase.
CD-Length = 196 residues,  98.0% aligned
Score =  210 bits (535), Expect = 1e-55
Identities = 98/192 (51%), Positives = 133/192 (69%)

COG0800, Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase 
[Carbohydrate transport and metabolism]
CD-Length = 211 residues,  99.5% aligned
Score =  241 bits (616), Expect = 5e-65
Identities = 107/210 (50%), Positives = 139/210 (66%)







   
Genomic Context:






   
Comment:


















    ReferenceID:7389




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24531




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32390




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3693_cdd.html


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:3693
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5896
                           PA3131_tr
                           translation of PA3131
                           215
                           99.53
                           99.53
                           0
                           1082.0
     

     
     
165219
                           gb|AAG06519.1|AE004737_5
                           (AE004737) probable aldolase [Pseudomonas aeruginosa PAO1]
                           215
                           99.53
                           99.53
                           0
                           1082.0
     

     
     
165223
                           emb|CAD18341.1|
                           (AL646083) PROBABLE BIFUNCTIONAL ALKH PROTEIN (KHG/KDPG ALDOLASE): 4-HYDROXY-2-OXOGLUTARATE ALDOLASE AND 2-DEHYDRO-3-DEOXYPHOSPHOGLUCONATE ALDOLASE [Ralstonia solanacearum]
                           216
                           49.07
                           63.88
                           9
                           525.0
     

     
     
165238
                           dbj|BAC73590.1|
                           (AP005044) putative 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase [Streptomyces avermitilis MA-4680]
                           224
                           48.66
                           61.16
                           14
                           514.0
     

     
     
165222
                           gb|AAQ57822.1|
                           (AE016910) 2-dehydro-3-deoxy-phosphogluconate aldolase [Chromobacterium violaceum ATCC 12472]
                           216
                           48.61
                           65.27
                           9
                           525.0
     

     






      

          
GC ORFID: 46695How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3131Glimmer Score: 

          
Start: 2898684Stop: 2898037

          
Length: 648


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3131 translation of PA3131Homolog Bit Score 421.0

          
Other Homologs:  t_PA3181 (ORF: BLASTX 189.0), psyr_15may02_Scaffold3_revised_gene4426 (ORF: BLASTX 171.0), t_PA3131 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACATTGCCGCTGGATCGGGTCCTGCTGCAGGCCAGCCCGGTATTGCCGGTGCTGGTGATCGAGGACGTG 
GCGCTGGCGCCCGACCTGGCGCGCGCGTTGTATGCGGGCGGCGTCACGGTGTTGGAAGTGACGCTGCGCACG 
CCGCAGGCGCTGGACGCGATCGCCGCCATCCATCGCGAGGTGCCCGAGGTCCTGCTGGGGGCGGGTACCCTG 
ATCCACACCGAGCAGTTTCTCGAGGCACGCGACGCGGGCGCGCAGTTCGCCGTCAGCCCCGGATGCACGCCG 
CGCCTTGCCGCCGCCGCGGAGGATGCCGGCCTGCCATACCTGCCCGGGGTGATGACGCCTTCGGAAGTGTTG 
CTGGCGCTGGAGTACGGTTATCGCTCGCTGAAGCTGTTCCCGGCCGATGGCACTGCCAGCGTGAAAATGCTG 
AAAAGCCTGAAGGGGCCGTTCACCGGCATCCGCTTCTGCCCGACCGGCGGCGTCAACCTGGACAACCTGCTG 
AATTTCCTCCGCCTGCCCAATGTCGCCTGTGTCGGCGGCACCTGGCTGGCGCCGCCGAGCTTGATCCGGGCG 
CGGGCCTGGGATCAGATCACACAACTGGCCAGGGAAGCGCGCGAACTGGCCGGCAGCCTGGAGCAGCATTGA