ViewGene
Locus Name:
GeneID:
Location:

GeneID:3685
TrivialName: PA14_16700
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_16700
PAO1 Ortholog Locus:PA3686
Sequence Length:648
Protein Length:215
Start: 1430423
Stop: 1431070
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07074.1|AE004788_4 (AE004788) adenylate kinase [Pseudomonas aeruginosa PAO1]
Identities = 215/215 (100%), Positives = 215/215 (100%)
Sequence:
ATGCGTGTGATTCTGCTCGGGGCACCCGGTGCCGGCAAAGGCACCCAGGCACGGTTCATCACCGAGAAGTTC
GGCATTCCGCAGATCTCCACCGGCGACATGCTGCGCGCCGCAGTCAAGGCCGGCAGCCCGCTCGGCCAGCAG
GTGAAAGGCGTGATGGACAGCGGCGGCCTGGTATCCGACGACATCATCATCGCCCTGATCAAGGAACGCATC
ACCGAGGCCGATTGCGCCAAGGGCTTCCTGTTCGACGGCTTCCCGCGGACCATCCCGCAGGCCGAAGCGCTG
AAGGACGCCGGCGTGACCATCGACCATGTGGTCGAGATCGCCGTCGACGACGAGGAGATCGTGTCGCGTATC
GCCGGTCGTCGCGTGCATCCGGCCTCCGGCCGCGTGTACCACACCGAGCACAACCCGCCGAAGGTCGCCGGC
AAGGACGACGTTACCGGCGAAGAGCTGATCCAGCGCGAGGACGACAAGGAAGAGACCGTGCGTCACCGCCTG
TCGGTCTACCATTCGCAGACCAAGCCGCTGGTCGACTTCTACCAGAAGCTGTCGGCCGCCGAAGGCACCCCG
AAATACCACAGCATCGCCGGCGTCGGCTCGGTCGAGCAGATCACCGCGAAAGTGCTTTCGGCCCTGAGCTGA
Translation:
MRVILLGAPGAGKGTQARFITEKFGIPQISTGDMLRAAVKAGSPLGQQVKGVMDSGGLVSDDIIIALIKERI
TEADCAKGFLFDGFPRTIPQAEALKDAGVTIDHVVEIAVDDEEIVSRIAGRRVHPASGRVYHTEHNPPKVAG
KDDVTGEELIQREDDKEETVRHRLSVYHSQTKPLVDFYQKLSAAEGTPKYHSIAGVGSVEQITAKVLSALS*
AnnotationID:3693GeneID:3685
AnnotatorUID: diggins
Modification Date/Time: 2005-04-21 11:11:29
Gene Name:adk
Confidence Code:2
GeneProduct:adenylate kinase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:pfam00406,COG0563
Secondary Functional Category(ies):
EC Number:2.7.4.3
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN67127.1|AE016341_10 (AE016779) adenylate kinase [Pseudomonas putida KT2440]
          Length = 216

 Score =  341 bits (875), Expect = 2e-93
 Identities = 175/216 (81%), Positives = 192/216 (88%), Gaps = 1/216 (0%)

>emb|CAE32502.1| (BX640443) adenylate kinase [Bordetella bronchiseptica]
          Length = 218

 Score =  299 bits (765), Expect = 9e-81
 Identities = 142/216 (65%), Positives = 178/216 (82%), Gaps = 2/216 (0%)

>emb|CAB84301.1| (AL162754) adenylate kinase [Neisseria meningitidis Z2491]
          Length = 215

 Score =  287 bits (734), Expect = 3e-77
 Identities = 143/214 (66%), Positives = 169/214 (78%), Gaps = 1/214 (0%)







 
Structural Features:
pfam00406, ADK, Adenylate kinase.
CD-Length = 187 residues,  98.4% aligned
Score =  268 bits (686), Expect = 4e-73
Identities = 108/184 (58%), Positives = 140/184 (76%), Gaps = 4/184 (2%)

COG0563, Adk, Adenylate kinase and related kinases 
[Nucleotide transport and metabolism]
CD-Length = 178 residues, 100.0% aligned
Score =  189 bits (482), Expect = 2e-49
Identities = 90/219 (41%), Positives = 128/219 (58%), Gaps = 45/219 (20%)






   
Genomic Context:






   
Comment:


















    ReferenceID:7373




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24515




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31860




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3685_cdd.html


    		




 
URL:

















    ReferenceID:34240




  
Author/Investigator(s):
        Sinha KM, Ghosh M, Das I, Datta AK.





  
Title:
        Molecular cloning and expression of adenosine kinase from Leishmania donovani: identification of unconventional P-loop motif.




  
PubMed:
        10215606


MedLine:
        




    
Source:
Biochem J. 1999 May 1;339 ( Pt 3):667-73.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10215606

















    ReferenceID:34241




  
Author/Investigator(s):
        von Schwartzenberg K, Kruse S, Reski R, Moffatt B, Laloue M.





  
Title:
        Cloning and characterization of an adenosine kinase from Physcomitrella involved in cytokinin metabolism.




  
PubMed:
        9680981


MedLine:
        




    
Source:
Plant J. 1998 Jan;13(2):249-57.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9680981

















    ReferenceID:34242




  
Author/Investigator(s):
        Feil E, Zhou J, Maynard Smith J, Spratt BG.





  
Title:
        A comparison of the nucleotide sequences of the adk and recA genes of pathogenic and commensal Neisseria species: evidence for extensive interspecies recombination within adk.




  
PubMed:
        8995060


MedLine:
        




    
Source:
J Mol Evol. 1996 Dec;43(6):631-40.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8995060

















    ReferenceID:34243




  
Author/Investigator(s):
        Koivula T, Hemila H.





  
Title:
        Nucleotide sequence of a Lactococcus lactis gene cluster encoding adenylate kinase, initiation factor 1 and ribosomal proteins.




  
PubMed:
        1783905


MedLine:
        




    
Source:
J Gen Microbiol. 1991 Nov;137 ( Pt 11):2595-600.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1783905

















    ReferenceID:34244




  
Author/Investigator(s):
        Brune M, Schumann R, Wittinghofer F.





  
Title:
        Cloning and sequencing of the adenylate kinase gene (adk) of Escherichia coli.




  
PubMed:
        2997739


MedLine:
        




    
Source:
Nucleic Acids Res. 1985 Oct 11;13(19):7139-51.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2997739









           
Homologs By Global Alignment 

           

       



     
Gene ID:3685
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5888
                           PA3686_tr
                           translation of PA3686
                           215
                           99.99
                           99.99
                           0
                           1086.0
     

     
     
164522
                           gb|AAG07074.1|AE004788_4
                           (AE004788) adenylate kinase [Pseudomonas aeruginosa PAO1]
                           215
                           99.99
                           99.99
                           0
                           1086.0
     

     
     
164523
                           gb|AAN67127.1|AE016341_10
                           (AE016779) adenylate kinase [Pseudomonas putida KT2440]
                           216
                           81.01
                           88.88
                           1
                           877.0
     

     
     
164524
                           dbj|BAA75818.1|
                           (AB024426) adenylate kinase [Pseudomonas putida]
                           216
                           81.01
                           88.88
                           1
                           877.0
     

     
     
164525
                           gb|AAO55029.1|
                           (AE016861) adenylate kinase [Pseudomonas syringae pv. tomato str. DC3000]
                           215
                           76.27
                           83.72
                           0
                           829.0
     

     






      

          
GC ORFID: 46687How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3686Glimmer Score: 

          
Start: 3523514Stop: 3522867

          
Length: 648


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3686 translation of PA3686Homolog Bit Score 422.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4602 (ORF: BLASTX 329.0), t_PA3686 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCGTGTGATTCTGCTCGGGGCACCCGGTGCCGGCAAAGGCACCCAGGCACGGTTCATCACCGAGAAGTTC 
GGCATTCCGCAGATCTCCACCGGCGACATGCTGCGCGCCGCAGTCAAGGCCGGCAGCCCGCTCGGCCAGCAG 
GTGAAAGGCGTGATGGACAGCGGCGGCCTGGTATCCGACGACATCATCATCGCCCTGATCAAGGAACGCATC 
ACCGAGGCCGATTGCGCCAAGGGCTTCCTGTTCGACGGCTTCCCGCGGACCATCCCGCAGGCCGAAGCGCTG 
AAGGACGCCGGCGTGACCATCGACCATGTGGTCGAGATCGCCGTCGACGACGAGGAGATCGTGTCGCGTATC 
GCCGGTCGTCGCGTGCATCCGGCCTCCGGCCGCGTGTACCACACCGAGCACAACCCGCCGAAGGTCGCCGGC 
AAGGACGACGTTACCGGCGAAGAGCTGATCCAGCGCGAGGACGACAAGGAAGAGACCGTGCGTCACCGCCTG 
TCGGTCTACCATTCGCAGACCAAGCCGCTGGTCGACTTCTACCAGAAGCTGTCGGCCGCCGAAGGCACCCCG 
AAATACCACAGCATCGCCGGCGTCGGCTCGGTCGAGCAGATCACCGCGAAAGTGCTTTCGGCCCTGAGCTGA