ViewGene
Locus Name:
GeneID:
Location:

GeneID:3557
TrivialName: PA14_23320
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_23320
PAO1 Ortholog Locus:PA3163
Sequence Length:690
Protein Length:229
Start: 2023200
Stop: 2023889
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06551.1|AE004740_4 (AE004740) cytidylate kinase [Pseudomonas aeruginosa PAO1]
Identities = 229/229 (100%), Positives = 229/229 (100%)
Sequence:
ATGAACGGCGCTGTACCGATGCTCGCCATCGATGGCCCCAGTGGCGCCGGCAAGGGCACGGTCGCCGGGCTG
CTCGCCCGGCGCCTGGGCTGGAACCTGCTGGATTCCGGGGCGCTTTATCGGCTGTTGGCGTTCGCCGCGGTC
AACCATGGTGTCGACCTGACCAATGAAGAGGCGCTGAAGGTCCTGGCTGCGCACCTCGATGTGCAGTTCGTC
GCCGCCGATGGCAGCCATGGGCAGCGCATCATTCTCGAAGGCGAGGAAGTGACCGATGTGATCCGTACCGAG
CAGGTCGGTGCCGGCGCTTCCCAGGTCGCGGCGCTGCCGGCCGTGCGCGATGCGCTGCTGCAGCGCCAGCGG
GCGTTTCGCGAGGCTCCGGGACTGGTGGCCGACGGCCGCGACATGGGCACCGTGGTATTTCCCGATGCGCCT
CTGAAGATCTTCCTCACCGCCTCGGCGGAGGAGCGTGCGCGTCGACGCTACCTGCAGTTGAAGGCGAAGGGC
GCGGATGTCGACCAGTCTGCCTTGCTGGAAGAAATCCGCGAGCGCGACGAGCGCGACAGCCAGCGCGCGGTC
GCGCCGCTGAAACCGGCCGATGACGCGATCCTGCTGGACTCCACCGAAATGAGCATCGAGGCGGTGGTCGAG
ACGATCATCCGGCACTGCGAGCGGCAGGGCTGGGACGTCTGA
Translation:
MNGAVPMLAIDGPSGAGKGTVAGLLARRLGWNLLDSGALYRLLAFAAVNHGVDLTNEEALKVLAAHLDVQFV
AADGSHGQRIILEGEEVTDVIRTEQVGAGASQVAALPAVRDALLQRQRAFREAPGLVADGRDMGTVVFPDAP
LKIFLTASAEERARRRYLQLKAKGADVDQSALLEEIRERDERDSQRAVAPLKPADDAILLDSTEMSIEAVVE
TIIRHCERQGWDV*
AnnotationID:3565GeneID:3557
AnnotatorUID: diggins
Modification Date/Time: 2005-04-13 11:11:33
Gene Name:cmk
Confidence Code:2
GeneProduct:cytidylate kinase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(18) Nucleotide biosynthesis and metabolism
Alternate Gene Product Name: cytidine monophosphate kinase
Functional Category Confidence Code:5
COGs:pfam02224,COG0283
Secondary Functional Category(ies):
EC Number:2.7.4.14
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAO55269.1| (AE016862) cytidylate kinase [Pseudomonas syringae pv. tomato str.
           DC3000]
          Length = 229

 Score =  334 bits (857), Expect = 2e-91
 Identities = 172/214 (80%), Positives = 190/214 (88%)

>gb|AAM86334.1|AE013881_4 (AE013881) cytidylate kinase [Yersinia pestis KIM]
          Length = 230

 Score =  270 bits (689), Expect = 6e-72
 Identities = 138/224 (61%), Positives = 175/224 (78%), Gaps = 2/224 (0%)

>gb|AAL19914.1| (AE008742) cytidine monophosphate (CMP) kinase [Salmonella
           typhimurium LT2]
          Length = 227

 Score =  269 bits (688), Expect = 8e-72
 Identities = 138/225 (61%), Positives = 176/225 (78%), Gaps = 2/225 (0%)








 
Structural Features:
pfam02224, Cytidylate_kin, Cytidylate kinase.
CD-Length = 158 residues,  98.7% aligned
Score =  182 bits (462), Expect = 4e-47
Identities = 84/158 (53%), Positives = 115/158 (72%), Gaps = 2/158 (1%)

COG0283, Cmk, Cytidylate kinase [Nucleotide transport and metabolism]
CD-Length = 222 residues,  97.7% aligned
Score =  281 bits (720), Expect = 5e-77
Identities = 132/222 (59%), Positives = 170/222 (76%), Gaps = 6/222 (2%)







   
Genomic Context:






   
Comment:


















    ReferenceID:7117




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24259




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32379




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3557_cdd.html


    		




 
URL:

















    ReferenceID:33941




  
Author/Investigator(s):
        Xie G, Brettin TS, Bonner CA, Jensen RA.





  
Title:
        Mixed-function supraoperons that exhibit overall conservation, albeit shuffled gene organization, across wide intergenomic distances within eubacteria.




  
PubMed:
        10518299


MedLine:
        




    
Source:
Microb Comp Genomics. 1999;4(1):5-28.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10518299

















    ReferenceID:33942




  
Author/Investigator(s):
        Xie G, Bonner CA, Jensen RA.





  
Title:
        A probable mixed-function supraoperon in Pseudomonas exhibits gene organization features of both intergenomic conservation and gene shuffling.




  
PubMed:
        10368439


MedLine:
        




    
Source:
J Mol Evol. 1999 Jul;49(1):108-21.
Erratum in:
    * J Mol Evol 2000 Feb;50(2):202.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10368439

















    ReferenceID:33943




  
Author/Investigator(s):
        Fricke J, Neuhard J, Kelln RA, Pedersen S.





  
Title:
        The cmk gene encoding cytidine monophosphate kinase is located in the rpsA operon and is required for normal replication rate in Escherichia coli.




  
PubMed:
        7836281


MedLine:
        




    
Source:
J Bacteriol. 1995 Feb;177(3):517-23.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7836281









           
Homologs By Global Alignment 

           

       



     
Gene ID:3557
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5675
                           PA3163_tr
                           translation of PA3163
                           229
                           99.99
                           99.99
                           0
                           1138.0
     

     
     
158034
                           gb|AAG06551.1|AE004740_4
                           (AE004740) cytidylate kinase [Pseudomonas aeruginosa PAO1]
                           229
                           99.99
                           99.99
                           0
                           1138.0
     

     
     
158035
                           gb|AAO55269.1|
                           (AE016862) cytidylate kinase [Pseudomonas syringae pv. tomato str. DC3000]
                           231
                           75.32
                           83.98
                           4
                           851.0
     

     
     
158036
                           gb|AAN67391.1|AE016365_6
                           (AE016780) cytidylate kinase [Pseudomonas putida KT2440]
                           230
                           74.34
                           83.91
                           3
                           837.0
     

     
     
158041
                           emb|CAD05380.1|
                           (AL627268) cytidylate kinase [Salmonella enterica subsp. enterica serovar Typhi]
                           230
                           60.86
                           76.95
                           4
                           683.0
     

     






      

          
GC ORFID: 46559How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3163Glimmer Score: 

          
Start: 2930731Stop: 2930042

          
Length: 690


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3163 translation of PA3163Homolog Bit Score 442.0

          
Other Homologs:  psyr_15may02_Scaffold8_revised_gene7733 (ORF: BLASTX 337.0), t_PA3163 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAACGGCGCTGTACCGATGCTCGCCATCGATGGCCCCAGTGGCGCCGGCAAGGGCACGGTCGCCGGGCTG 
CTCGCCCGGCGCCTGGGCTGGAACCTGCTGGATTCCGGGGCGCTTTATCGGCTGTTGGCGTTCGCCGCGGTC 
AACCATGGTGTCGACCTGACCAATGAAGAGGCGCTGAAGGTCCTGGCTGCGCACCTCGATGTGCAGTTCGTC 
GCCGCCGATGGCAGCCATGGGCAGCGCATCATTCTCGAAGGCGAGGAAGTGACCGATGTGATCCGTACCGAG 
CAGGTCGGTGCCGGCGCTTCCCAGGTCGCGGCGCTGCCGGCCGTGCGCGATGCGCTGCTGCAGCGCCAGCGG 
GCGTTTCGCGAGGCTCCGGGACTGGTGGCCGACGGCCGCGACATGGGCACCGTGGTATTTCCCGATGCGCCT 
CTGAAGATCTTCCTCACCGCCTCGGCGGAGGAGCGTGCGCGTCGACGCTACCTGCAGTTGAAGGCGAAGGGC 
GCGGATGTCGACCAGTCTGCCTTGCTGGAAGAAATCCGCGAGCGCGACGAGCGCGACAGCCAGCGCGCGGTC 
GCGCCGCTGAAACCGGCCGATGACGCGATCCTGCTGGACTCCACCGAAATGAGCATCGAGGCGGTGGTCGAG 
ACGATCATCCGGCACTGCGAGCGGCAGGGCTGGGACGTCTGA