ViewGene
Locus Name:
GeneID:
Location:

GeneID:3530
TrivialName: PA14_37590
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_37590
PAO1 Ortholog Locus:PA2081
Sequence Length:642
Protein Length:213
Start: 3345406
Stop: 3346047
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG05469.1|AE004635_7 (AE004635) hypothetical protein [Pseudomonas aeruginosa PAO1]
Identities = 212/213 (99%), Positives = 213/213 (100%)
Sequence:
ATGACTTCGCTCCGCTACTGGGACATCAGTCCCGCCCTCGACCCGAGCACGCCGACCTGGCCCGGCGACACG
CCGTTCCAGCAGGAATGGGCGGCGCGGCTGGACGAGCAGTGCCCGGTCAACGTCGGCCGGATCACCCTTTCG
CCGCATACCGGCGCCCACGTCGACGGTCCCCTGCACTACCGCGCCGACGGCCTGCCCATCGGCCAGGTGCCG
CTGGACATCTACATGGGACCGTGCCGGGTGATCCACTGTATCGGCGCTAACCCGCTGGTGACCCCCGAACAC
CTCGCCGGCCAGCTCGACGACCTGCCCTCGCGGGTGCTGCTACGGACCTTCGAACGGGTCCCGGCGAACTGG
CCGGAAGGCTTCTGCGCTATCGCTCCGGCCACCATCGAGTGCCTCGCCGAGCGCGGCGTCAGGCTGGTCGGC
ATCGACACCCCGTCGCTCGACCCCCAGCACTCCAAGACCCTCGACGCCCACCACGCGGTGGGCCGCCACGGC
ATGGCGATCCTCGAAGGCGTGGTCCTCGACGACGTGCCCGCCGGCGACTACGAACTACTCGCCCTGCCGCTG
AAATTCACCCACCTCGATGCCAGCCCAGTGCGTGCCGTGCTGCGCGCCCTGCCTACCGCGGAGTAA
Translation:
MTSLRYWDISPALDPSTPTWPGDTPFQQEWAARLDEQCPVNVGRITLSPHTGAHVDGPLHYRADGLPIGQVP
LDIYMGPCRVIHCIGANPLVTPEHLAGQLDDLPSRVLLRTFERVPANWPEGFCAIAPATIECLAERGVRLVG
IDTPSLDPQHSKTLDAHHAVGRHGMAILEGVVLDDVPAGDYELLALPLKFTHLDASPVRAVLRALPTAE*
AnnotationID:3538GeneID:3530
AnnotatorUID: danlee
Modification Date/Time: 2006-01-27 13:01:00
Gene Name:kynB
Confidence Code:1
GeneProduct:kynurenine formamidase, KynB
Cell Localization:()
Synonyms:PA2081
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(2) Amino acid biosynthesis and metabolism
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG1878,pfam04199
Secondary Functional Category(ies):
EC Number:
Status:ACTIVE
Pathway:
aerobic degradation of L-tryptophan (kynurenine pathway)
Homology:






 
Structural Features:
COG1878, COG1878, Predicted metal-dependent hydrolase 
CD-Length = 218 residues, 100.0% aligned
Score =  193 bits (492), Expect = 1e-50
Identities = 82/219 (37%), Positives = 112/219 (51%), Gaps = 10/219 (4%)

pfam04199, Cyclase, Putative cyclase.
CD-Length = 204 residues, 100.0% aligned
Score =  165 bits (418), Expect = 5e-42
Identities = 74/204 (36%), Positives = 103/204 (50%), Gaps = 15/204 (7%)






   
Genomic Context:
kynB is next to kynA and kynU






   
Comment:


















    ReferenceID:7063




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24205




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:32626




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3530_cdd.html


    		




 
URL:

















    ReferenceID:38274




  
Author/Investigator(s):
        Kurnasov O, Jablonski L, Polanuyer B, Dorrestein P, Begley T, Osterman A.





  
Title:
        Aerobic tryptophan degradation pathway in bacteria: novel kynurenine formamidase.




  
PubMed:
        14592712


MedLine:
        




    
Source:
FEMS Microbiol Lett. 2003 Oct 24;227(2):219-27.






    
Reference Type: 







    
Data:


    		




 
URL:









           
Homologs By Global Alignment 

           

       



     
Gene ID:3530
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5633
                           PA2081_tr
                           translation of PA2081
                           213
                           99.53
                           99.99
                           0
                           1148.0
     

     
     
157052
                           gb|AAG05469.1|AE004635_7
                           (AE004635) hypothetical protein PA2081 [Pseudomonas aeruginosa PAO1]
                           213
                           99.53
                           99.99
                           0
                           1148.0
     

     
     
157053
                           emb|CAD14290.1|
                           (AL646060) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]
                           214
                           69.62
                           76.63
                           6
                           784.0
     

     
     
157054
                           gb|AAL65290.1|
                           (AY271621) QbsH [Pseudomonas fluorescens]
                           218
                           61.92
                           71.55
                           5
                           689.0
     

     
     
157055
                           emb|CAE33751.1|
                           (BX640447) conserved hypothetical protein [Bordetella bronchiseptica] [Bordetella bronchiseptica RB50]
                           214
                           56.07
                           64.95
                           6
                           621.0
     

     






      

          
GC ORFID: 46532How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2081Glimmer Score: 

          
Start: 1608508Stop: 1607867

          
Length: 642


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TAATruncated Stop: 

          
Homolog: t_PA2081 translation of PA2081Homolog Bit Score 446.0

          
Other Homologs:  t_PA2081 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGACTTCGCTCCGCTACTGGGACATCAGTCCCGCCCTCGACCCGAGCACGCCGACCTGGCCCGGCGACACG 
CCGTTCCAGCAGGAATGGGCGGCGCGGCTGGACGAGCAGTGCCCGGTCAACGTCGGCCGGATCACCCTTTCG 
CCGCATACCGGCGCCCACGTCGACGGTCCCCTGCACTACCGCGCCGACGGCCTGCCCATCGGCCAGGTGCCG 
CTGGACATCTACATGGGACCGTGCCGGGTGATCCACTGTATCGGCGCTAACCCGCTGGTGACCCCCGAACAC 
CTCGCCGGCCAGCTCGACGACCTGCCCTCGCGGGTGCTGCTACGGACCTTCGAACGGGTCCCGGCGAACTGG 
CCGGAAGGCTTCTGCGCTATCGCTCCGGCCACCATCGAGTGCCTCGCCGAGCGCGGCGTCAGGCTGGTCGGC 
ATCGACACCCCGTCGCTCGACCCCCAGCACTCCAAGACCCTCGACGCCCACCACGCGGTGGGCCGCCACGGC 
ATGGCGATCCTCGAAGGCGTGGTCCTCGACGACGTGCCCGCCGGCGACTACGAACTACTCGCCCTGCCGCTG 
AAATTCACCCACCTCGATGCCAGCCCAGTGCGTGCCGTGCTGCGCGCCCTGCCTACCGCGGAGTAA