ViewGene
Locus Name:
GeneID:
Location:

GeneID:3524
TrivialName: PA14_06060
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_06060
PAO1 Ortholog Locus:PA0463
Sequence Length:690
Protein Length:229
Start: 536068
Stop: 536757
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG03852.1|AE004484_4 (AE004484) two-component response regulator CreB [Pseudomonas aeruginosa PAO1]
Identities = 228/229 (99%), Positives = 228/229 (99%)
Sequence:
ATGCCGCATATCCTGATCGTCGAAGATGAAGCCGCGATTGCCGACACCCTGCTCTACGCCCTGCAGGCCGAA
GGCTTCGCCACCACCTGGGTGACCCTCGCCGGCGAGGCGCTGGTGTTGCAGGAGCGCCAGCCGGCGGACCTG
CTGATCCTCGACGTCGGTCTGCCGGACATCAGCGGTTTCGAGGCCTGCAAGCGCCTGCGGCGGTTCTCCGAG
GTGCCGGTGATCTTCCTCACCGCGCGCGATGCCGAGATCGACCGCGTGGTCGGCCTGGAGATCGGCGCCGAC
GACTACGTGGTCAAGCCGTTCAGCCCGCGCGAGGTGGCGGCGCGGGTCAAGGCCATCCTCAAGCGCATGGCG
CCGCGCCCGGCGGCGCTGGAAGAGGCCGCGCCGAGCGGGCCGTTCCAGGTCGACGAGGAGCGCGTGCGGATC
CACTACCGCGACACCCCGCTCAACCTCACCCGCCACGAGTTCCGCCTGTTGCAGACGCTGCTCGGGCAGCCC
GAGCGGGTATTCAGCCGCGAGCAGTTGCTCGACGCCCTCGGCGTCGCCAGCGAGGCCGGCTACGAGCGCAAC
ATCGACAGCCACATCAAGAGTCTGCGCGCCAAGCTGCGCCAGGTGAACGAACGCGGCGAAGCGATCCAGACC
CATCGCGGCCTGGGCTACAGCTACAGCCCGGACCACGCCTGA
Translation:
MPHILIVEDEAAIADTLLYALQAEGFATTWVTLAGEALVLQERQPADLLILDVGLPDISGFEACKRLRRFSE
VPVIFLTARDAEIDRVVGLEIGADDYVVKPFSPREVAARVKAILKRMAPRPAALEEAAPSGPFQVDEERVRI
HYRDTPLNLTRHEFRLLQTLLGQPERVFSREQLLDALGVASEAGYERNIDSHIKSLRAKLRQVNERGEAIQT
HRGLGYSYSPDHA*
AnnotationID:3532GeneID:3524
AnnotatorUID: diggins
Modification Date/Time: 2005-03-27 08:08:32
Gene Name:creB
Confidence Code:2
GeneProduct:two-component response regulator CreB
Cell Localization:()
Synonyms:blrA
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(28) Two-component regulatory systems
Alternate Gene Product Name:beta-lactamase response regulator
Functional Category Confidence Code:5
COGs:COG0745
Secondary Functional Category(ies):transcriptional regulator
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAC45062.1| (U67069) response regulator protein [Aeromonas jandaei]
          Length = 223

 Score =  240 bits (612), Expect = 5e-63
 Identities = 122/220 (55%), Positives = 157/220 (71%), Gaps = 6/220 (2%)

>gb|AAM41967.1| (AE012382) two-component system regulatory protein [Xanthomonas
           campestris pv. campestris str. ATCC 33913]
          Length = 231

 Score =  233 bits (594), Expect = 7e-61
 Identities = 123/221 (55%), Positives = 156/221 (70%), Gaps = 1/221 (0%)

>emb|CAD69002.1| (AJ548796) beta-lactamase response regulator [Aeromonas hydrophila]
          Length = 224

 Score =  230 bits (587), Expect = 4e-60
 Identities = 119/220 (54%), Positives = 152/220 (69%), Gaps = 5/220 (2%)








 
Structural Features:
COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain 
and a winged-helix DNA-binding domain 
[Signal transduction mechanisms / Transcription]
CD-Length = 229 residues, 100.0% aligned
Score =  208 bits (531), Expect = 3e-55
Identities = 97/230 (42%), Positives = 126/230 (54%), Gaps = 4/230 (1%)








   
Genomic Context:






   
Comment:


















    ReferenceID:7051




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24193




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:33791




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3524_cdd.html


    		




 
URL:

















    ReferenceID:35340




  
Author/Investigator(s):
        Niumsup P, Simm AM, Nurmahomed K, Walsh TR, Bennett PM, Avison MB.





  
Title:
        Genetic linkage of the penicillinase gene, amp, and blrAB, encoding the regulator of beta-lactamase expression in Aeromonas spp.




  
PubMed:
        12746371


MedLine:
        




    
Source:
J Antimicrob Chemother. 2003 Jun;51(6):1351-8. Epub 2003 May 13.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12746371

















    ReferenceID:35341




  
Author/Investigator(s):
        Nishiya Y, Toda A, Imanaka T.





  
Title:
        Gene cluster for creatinine degradation in Arthrobacter sp. TE1826.




  
PubMed:
        9563845


MedLine:
        




    
Source:
Mol Gen Genet. 1998 Mar;257(5):581-6.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9563845









           
Homologs By Global Alignment 

           

       



     
Gene ID:3524
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5618
                           PA0463_tr
                           translation of PA0463
                           229
                           99.56
                           99.56
                           0
                           1150.0
     

     
     
156533
                           gb|AAG03852.1|AE004484_4
                           (AE004484) two-component response regulator CreB [Pseudomonas aeruginosa PAO1]
                           229
                           99.56
                           99.56
                           0
                           1150.0
     

     
     
156534
                           gb|AAC45062.1|
                           (U67069) response regulator protein [Aeromonas jandaei]
                           231
                           52.81
                           67.96
                           10
                           604.0
     

     
     
156537
                           gb|AAM37700.1|
                           (AE011926) two-component system regulatory protein [Xanthomonas axonopodis pv. citri str. 306]
                           233
                           52.36
                           66.52
                           7
                           581.0
     

     
     
156535
                           gb|AAM41967.1|
                           (AE012382) two-component system regulatory protein [Xanthomonas campestris pv. campestris str. ATCC 33913]
                           237
                           52.32
                           66.66
                           14
                           591.0
     

     






      

          
GC ORFID: 46526How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA0463Glimmer Score: 

          
Start: 6337410Stop: 6338099

          
Length: 690


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA0463 translation of PA0463Homolog Bit Score 447.0

          
Other Homologs:  psyr_15may02_Scaffold7_revised_gene7114 (ORF: BLASTX 165.0), t_PA0463 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGCCGCATATCCTGATCGTCGAAGATGAAGCCGCGATTGCCGACACCCTGCTCTACGCCCTGCAGGCCGAA 
GGCTTCGCCACCACCTGGGTGACCCTCGCCGGCGAGGCGCTGGTGTTGCAGGAGCGCCAGCCGGCGGACCTG 
CTGATCCTCGACGTCGGTCTGCCGGACATCAGCGGTTTCGAGGCCTGCAAGCGCCTGCGGCGGTTCTCCGAG 
GTGCCGGTGATCTTCCTCACCGCGCGCGATGCCGAGATCGACCGCGTGGTCGGCCTGGAGATCGGCGCCGAC 
GACTACGTGGTCAAGCCGTTCAGCCCGCGCGAGGTGGCGGCGCGGGTCAAGGCCATCCTCAAGCGCATGGCG 
CCGCGCCCGGCGGCGCTGGAAGAGGCCGCGCCGAGCGGGCCGTTCCAGGTCGACGAGGAGCGCGTGCGGATC 
CACTACCGCGACACCCCGCTCAACCTCACCCGCCACGAGTTCCGCCTGTTGCAGACGCTGCTCGGGCAGCCC 
GAGCGGGTATTCAGCCGCGAGCAGTTGCTCGACGCCCTCGGCGTCGCCAGCGAGGCCGGCTACGAGCGCAAC 
ATCGACAGCCACATCAAGAGTCTGCGCGCCAAGCTGCGCCAGGTGAACGAACGCGGCGAAGCGATCCAGACC 
CATCGCGGCCTGGGCTACAGCTACAGCCCGGACCACGCCTGA