ViewGene
Locus Name:
GeneID:
Location:

GeneID:3518
TrivialName: PA14_64950
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_64950
PAO1 Ortholog Locus:PA4918
Sequence Length:660
Protein Length:219
Start: 5789189
Stop: 5789848
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08303.1|AE004905_1 (AE004905) hypothetical protein [Pseudomonas aeruginosa PAO1]
Identities = 217/219 (99%), Positives = 217/219 (99%)
Sequence:
ATGAATCGCCCCAGCAAGATCGCCAGCTTCGATGTCGACGCCCAGAAAGGCTTCACCCCGCTGTGCCCGGAC
GAACTGCCGGTGCCCGGCGGCGACGCCATCGGCGCCGCCCTCAACCAACTGGCCAGCCGCGCCGCGCTGCGC
CTGGGCAGCAAGGACGCGCACAGCCCGAAGGCTGCCTGGGTAGTGGAAAGCGCCGAGCAGATGCTGCGGCCG
CTGGCCTATCCGGATGCCGACCTGACCTGGGTGAGCCACTGCGTACCGGGTACGCCGGGCTTCGAGCTGCTC
GACGAACTGCCGCGGCCGATCGACTACGACTTCTTCGTCTGGAAGGGCGTGGAGCCGGACCTGCACCCCTAC
GGCGCCTGCTACCACGATCTGGCGGAACGCCGCAGCACCGGGGTCATCGAATACCTGAGGCAGAATGGCGTG
AGCCATGTGCTGGTGGGTGGCCTGGCGCTGGACTACTGCGTGAAGAACACCGCCCTGCAACTGCGCCGCGCC
GGTTTCGAGGTGCTGCTCTACCTGCCCGCCTGCCGGGCCATCGCCGAGGACACCGCGCAGCGGGCCTGCGAC
GAGATGCGCGACGCCGGGGTGATCCTCTGCGCCGACCTGGAACGACTGGATAGCGCCCTCACCGGCGCCGAC
AAGGAGAAGTGA
Translation:
MNRPSKIASFDVDAQKGFTPLCPDELPVPGGDAIGAALNQLASRAALRLGSKDAHSPKAAWVVESAEQMLRP
LAYPDADLTWVSHCVPGTPGFELLDELPRPIDYDFFVWKGVEPDLHPYGACYHDLAERRSTGVIEYLRQNGV
SHVLVGGLALDYCVKNTALQLRRAGFEVLLYLPACRAIAEDTAQRACDEMRDAGVILCADLERLDSALTGAD
KEK*
AnnotationID:3526GeneID:3518
AnnotatorUID: diggins
Modification Date/Time: 2005-04-26 07:07:22
Gene Name:pncA
Confidence Code:2
GeneProduct:nicotinamidase
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(8) Central intermediary metabolism
Alternate Gene Product Name:pyrazinamidase
Functional Category Confidence Code:5
COGs:cd01011
Secondary Functional Category(ies):putative enzyme
EC Number:3.5.1.19
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAF42465.1| (AE002563) pyrazinamidase/nicotinamidase PncA, putative [Neisseria
           meningitidis MC58]
          Length = 211

 Score =  220 bits (561), Expect = 4e-57
 Identities = 108/204 (52%), Positives = 141/204 (69%), Gaps = 1/204 (0%)








 
Structural Features:
cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase).
CD-Length = 196 residues, 100.0% aligned
Score =  225 bits (575), Expect = 3e-60







   
Genomic Context:






   
Comment:


















    ReferenceID:7039




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:24181




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:35103




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3518_cdd.html


    		




 
URL:

















    ReferenceID:35929




  
Author/Investigator(s):
        Frothingham R, Meeker-O'Connell WA, Talbot EA, George JW, Kreuzer KN.





  
Title:
        Identification, cloning, and expression of the Escherichia coli pyrazinamidase and nicotinamidase gene, pncA.




  
PubMed:
        8726014


MedLine:
        




    
Source:
Antimicrob Agents Chemother. 1996 Jun;40(6):1426-31.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=8726014









           
Homologs By Global Alignment 

           

       



     
Gene ID:3518
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5612
                           PA4918_tr
                           translation of PA4918
                           219
                           99.08
                           99.08
                           0
                           1150.0
     

     
     
156394
                           gb|AAG08303.1|AE004905_1
                           (AE004905) hypothetical protein PA4918 [Pseudomonas aeruginosa PAO1]
                           219
                           99.08
                           99.08
                           0
                           1150.0
     

     
     
156399
                           emb|CAE43766.1|
                           (BX640421) conserved hypothetical protein [Bordetella pertussis] [Bordetella pertussis Tohama I]
                           229
                           58.07
                           65.50
                           24
                           651.0
     

     
     
156398
                           emb|CAE37808.1|
                           (BX640430) conserved hypothetical protein [Bordetella parapertussis]
                           229
                           58.07
                           65.50
                           24
                           651.0
     

     
     
156397
                           emb|CAE32456.1|
                           (BX640443) conserved hypothetical protein [Bordetella bronchiseptica] [Bordetella bronchiseptica RB50]
                           229
                           58.07
                           65.50
                           24
                           651.0
     

     






      

          
GC ORFID: 46520How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA4918Glimmer Score: 

          
Start: 5052870Stop: 5053529

          
Length: 660


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA4918 translation of PA4918Homolog Bit Score 447.0

          
Other Homologs:  t_PA4918 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAATCGCCCCAGCAAGATCGCCAGCTTCGATGTCGACGCCCAGAAAGGCTTCACCCCGCTGTGCCCGGAC 
GAACTGCCGGTGCCCGGCGGCGACGCCATCGGCGCCGCCCTCAACCAACTGGCCAGCCGCGCCGCGCTGCGC 
CTGGGCAGCAAGGACGCGCACAGCCCGAAGGCTGCCTGGGTAGTGGAAAGCGCCGAGCAGATGCTGCGGCCG 
CTGGCCTATCCGGATGCCGACCTGACCTGGGTGAGCCACTGCGTACCGGGTACGCCGGGCTTCGAGCTGCTC 
GACGAACTGCCGCGGCCGATCGACTACGACTTCTTCGTCTGGAAGGGCGTGGAGCCGGACCTGCACCCCTAC 
GGCGCCTGCTACCACGATCTGGCGGAACGCCGCAGCACCGGGGTCATCGAATACCTGAGGCAGAATGGCGTG 
AGCCATGTGCTGGTGGGTGGCCTGGCGCTGGACTACTGCGTGAAGAACACCGCCCTGCAACTGCGCCGCGCC 
GGTTTCGAGGTGCTGCTCTACCTGCCCGCCTGCCGGGCCATCGCCGAGGACACCGCGCAGCGGGCCTGCGAC 
GAGATGCGCGACGCCGGGGTGATCCTCTGCGCCGACCTGGAACGACTGGATAGCGCCCTCACCGGCGCCGAC 
AAGGAGAAGTGA