ViewGene
Locus Name:
GeneID:
Location:

GeneID:3295
TrivialName: PA14_69470
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_69470
PAO1 Ortholog Locus:PA5261
Sequence Length:747
Protein Length:248
Start: 6195504
Stop: 6194758
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG08646.1|AE004938_8 (AE004938) alginate biosynthesis regulatory protein AlgR [Pseudomonas aeruginosa PAO1]
Identities = 248/248 (100%), Positives = 248/248 (100%)
Sequence:
ATGAATGTCCTGATTGTCGATGACGAACCTCTGGCGCGAGAGCGCCTGGCCCGATTGGTAGGGCAACTGGAC
GGCTATCGCGTCCTCGAGCCCTCGGCCAGCAATGGCGAAGAAGCGCTGACGCTGATCGACAGCCTCAAGCCC
GATATCGTCCTGCTGGATATCCGCATGCCCGGTCTGGACGGCCTCCAGGTCGCGGCCAGACTCTGCGAGCGG
GAAGCGCCGCCGGCTGTGATCTTCTGCACGGCCCATGACGAATTCGCCCTGGAAGCCTTCCAGGTCAGCGCC
GTGGGCTACCTGGTCAAGCCGGTGCGCAGCGAAGACCTGGCCGAGGCGTTGAAGAAAGCCTCGCGACCGAAC
CGCGTGCAACTGGCCGCGCTGACCAAGCCCCCGGCCTCCGGCGGCAGCGGTCCGCGCAGCCACATCAGTGCG
CGGACCCGCAAGGGGATCGAGCTGATCCCGCTGGAAGAGGTGATCTTCTTCATTGCCGACCACAAGTACGTG
ACCTTGCGTCATGCGCAGGGCGAGGTGCTGCTGGACGAGCCGTTGAAGGCGCTGGAAGACGAGTTCGGCGAG
CGCTTCGTGCGCATCCACCGCAACGCGCTGGTCGCCCGCGAACGGATCGAACGCCTGCAGCGTACGCCGCTG
GGGCATTTCCAGCTCTACCTGAAAGGCCTCGACGGCGATGCACTGACCGTCAGCCGGCGGCACGTGGCCGGG
GTCAGGCGTCTGATGCATCAGCTCTGA
Translation:
MNVLIVDDEPLARERLARLVGQLDGYRVLEPSASNGEEALTLIDSLKPDIVLLDIRMPGLDGLQVAARLCER
EAPPAVIFCTAHDEFALEAFQVSAVGYLVKPVRSEDLAEALKKASRPNRVQLAALTKPPASGGSGPRSHISA
RTRKGIELIPLEEVIFFIADHKYVTLRHAQGEVLLDEPLKALEDEFGERFVRIHRNALVARERIERLQRTPL
GHFQLYLKGLDGDALTVSRRHVAGVRRLMHQL*
AnnotationID:3303GeneID:3295
AnnotatorUID: diggins
Modification Date/Time: 2005-03-16 07:07:58
Gene Name:algR
Confidence Code:1
GeneProduct:alginate biosynthesis regulatory protein AlgR
Cell Localization:()
Synonyms:
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(28) Two-component regulatory systems
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG3279,cd00156,pfam04397
Secondary Functional Category(ies):Secreted Factors (toxins, enzymes, alginate)
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAD31823.1|AF131199_2 (AF131199) alginate biosynthesis regulatory protein [Pseudomonas
           syringae pv. syringae]
          Length = 248

 Score =  430 bits (1105), Expect = e-120
 Identities = 214/248 (86%), Positives = 234/248 (94%)

>gb|AAO53681.1| (AE016856) alginate biosynthesis regulatory protein AlgR
           [Pseudomonas syringae pv. tomato str. DC3000]
          Length = 248

 Score =  416 bits (1068), Expect = e-116
 Identities = 204/248 (82%), Positives = 232/248 (93%)

>gb|AAD04864.1| (AF077237) encystment and alginate biosynthesis regulatory protein
           [Azotobacter vinelandii]
          Length = 251

 Score =  398 bits (1022), Expect = e-110
 Identities = 199/246 (80%), Positives = 221/246 (89%)






 
Structural Features:
COG3279, LytT, Response regulator of the LytR/AlgR family 
[Transcription / Signal transduction mechanisms]
CD-Length = 244 residues,  99.6% aligned
Score =  173 bits (439), Expect = 2e-44
Identities = 92/250 (36%), Positives = 147/250 (58%), Gaps = 9/250 (3%)

cd00156, REC, Signal receiver domain
CD-Length = 113 residues,  99.1% aligned
Score =   99 bits (249), Expect = 2e-22
Identities = 55/115 (47%), Positives = 74/115 (64%), Gaps = 5/115 (4%)

pfam04397, LytTR, LytTr DNA-binding domain.
CD-Length = 105 residues, 100.0% aligned
Score = 91.4 bits (227), Expect = 9e-20
Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 3/107 (2%)






   
Genomic Context:






   
Comment:


















    ReferenceID:6593




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:23735




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:34819




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3295_cdd.html


    		




 
URL:

















    ReferenceID:35731




  
Author/Investigator(s):
        Deretic V, Dikshit R, Konyecsni WM, Chakrabarty AM, Misra TK.





  
Title:
        The algR gene, which regulates mucoidy in Pseudomonas aeruginosa, belongs to a class of environmentally responsive genes.




  
PubMed:
        2493441


MedLine:
        




    
Source:
J Bacteriol. 1989 Mar;171(3):1278-83.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=2493441









           
Homologs By Global Alignment 

           

       



     
Gene ID:3295
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5291
                           PA5261_tr
                           translation of PA5261
                           248
                           99.99
                           99.99
                           0
                           1245.0
     

     
     
148285
                           gb|AAG08646.1|AE004938_8
                           (AE004938) alginate biosynthesis regulatory protein AlgR [Pseudomonas aeruginosa PAO1]
                           248
                           99.99
                           99.99
                           0
                           1245.0
     

     
     
148286
                           gb|AAA25704.1|
                           (M23230) mucoidy regulatory protein AlgR [Pseudomonas aeruginosa]
                           248
                           99.99
                           99.99
                           0
                           1245.0
     

     
     
148287
                           gb|AAD31823.1|AF131199_2
                           (AF131199) alginate biosynthesis regulatory protein [Pseudomonas syringae pv. syringae]
                           248
                           86.29
                           94.35
                           0
                           1105.0
     

     
     
148288
                           gb|AAO53681.1|
                           (AE016856) alginate biosynthesis regulatory protein AlgR [Pseudomonas syringae pv. tomato str. DC3000]
                           248
                           82.25
                           93.54
                           0
                           1068.0
     

     






      

          
GC ORFID: 46297How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA5261Glimmer Score: 

          
Start: 5459191Stop: 5458445

          
Length: 747


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA5261 translation of PA5261Homolog Bit Score 484.0

          
Other Homologs:  psyr_15may02_Scaffold2_revised_gene4065 (ORF: BLASTX 432.0), t_PA5261 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGAATGTCCTGATTGTCGATGACGAACCTCTGGCGCGAGAGCGCCTGGCCCGATTGGTAGGGCAACTGGAC 
GGCTATCGCGTCCTCGAGCCCTCGGCCAGCAATGGCGAAGAAGCGCTGACGCTGATCGACAGCCTCAAGCCC 
GATATCGTCCTGCTGGATATCCGCATGCCCGGTCTGGACGGCCTCCAGGTCGCGGCCAGACTCTGCGAGCGG 
GAAGCGCCGCCGGCTGTGATCTTCTGCACGGCCCATGACGAATTCGCCCTGGAAGCCTTCCAGGTCAGCGCC 
GTGGGCTACCTGGTCAAGCCGGTGCGCAGCGAAGACCTGGCCGAGGCGTTGAAGAAAGCCTCGCGACCGAAC 
CGCGTGCAACTGGCCGCGCTGACCAAGCCCCCGGCCTCCGGCGGCAGCGGTCCGCGCAGCCACATCAGTGCG 
CGGACCCGCAAGGGGATCGAGCTGATCCCGCTGGAAGAGGTGATCTTCTTCATTGCCGACCACAAGTACGTG 
ACCTTGCGTCATGCGCAGGGCGAGGTGCTGCTGGACGAGCCGTTGAAGGCGCTGGAAGACGAGTTCGGCGAG 
CGCTTCGTGCGCATCCACCGCAACGCGCTGGTCGCCCGCGAACGGATCGAACGCCTGCAGCGTACGCCGCTG 
GGGCATTTCCAGCTCTACCTGAAAGGCCTCGACGGCGATGCACTGACCGTCAGCCGGCGGCACGTGGCCGGG 
GTCAGGCGTCTGATGCATCAGCTCTGA