ViewGene
Locus Name:
GeneID:
Location:

GeneID:3180
TrivialName: PA14_26210
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_26210
PAO1 Ortholog Locus:PA2926
Sequence Length:768
Protein Length:255
Start: 2288456
Stop: 2287689
Strand: -
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG06314.1|AE004718_11 (AE004718) histidine transport protein HisP [Pseudomonas aeruginosa PAO1]
Identities = 253/255 (99%), Positives = 254/255 (99%)
Sequence:
ATGTACAGCCTGCAGGTCGAAGACATCCACAAGCGCTACGGCAGCCATGAGGTGCTCAGGGGCGTTTCGCTC
AGGGCCGGCAAGGGAGACGTGATCAGCATCATCGGCTCCTCCGGCTCGGGCAAGAGCACCTTCCTGCGCTGC
GTCAACTTCCTGGAAAAGCCCTGTGCCGGGCGCATCCGCGTCGGCGACGAGGAACTGCGCACCCGTCCCGGC
GCCCTGGGCGAGCTGCGCGCCGCCGATCCCCGGCAGTTGCAGAGGATCCGCAGCCGGCTGGCGATGGTCTTC
CAGCATTTCAACCTGTGGAGCCACCTGACGGTGCTGGAGAACGTGGTCGAGTGCCCGGTCAACGTCCTGAGA
ATGAACCGCGACGACGCCGTGGCCCGCGCGCGCCACTACCTGGCCAAGGTCGGCCTGGCGGAGAAGGTCGAA
CGGCAGTATCCCTGCGAACTCTCCGGCGGCCAGCAACAGCGCGTGGCGATCGCCCGCGCCCTGGCCATGGAG
CCGCAGGTGATGCTGTTCGACGAACCGACCTCGGCGCTCGATCCGGAACTGGTCGGCGAAGTGCTGAAAGTC
ATGCAGCAGTTGGCCGAGGAAGGTCGCACCATGGTCCTGGTCACCCACGAGATGGCCTTCGCCCGCCAGGTT
TCCAGCCATGTGATCTTCCTCCACCAGGGCGTGATCGAAGAGCAAGGGACGCCGGACCAGGTGTTCGGCGCG
CCGCGCAGCGAGCGCCTGCGCCAGTTCCTCGCCGGCAACCTGAAATGA
Translation:
MYSLQVEDIHKRYGSHEVLRGVSLRAGKGDVISIIGSSGSGKSTFLRCVNFLEKPCAGRIRVGDEELRTRPG
ALGELRAADPRQLQRIRSRLAMVFQHFNLWSHLTVLENVVECPVNVLRMNRDDAVARARHYLAKVGLAEKVE
RQYPCELSGGQQQRVAIARALAMEPQVMLFDEPTSALDPELVGEVLKVMQQLAEEGRTMVLVTHEMAFARQV
SSHVIFLHQGVIEEQGTPDQVFGAPRSERLRQFLAGNLK*
AnnotationID:3188GeneID:3180
AnnotatorUID: diggins
Modification Date/Time: 2005-04-08 10:10:51
Gene Name:hisP
Confidence Code:2
GeneProduct:ATP-binding component of histidine transport
Cell Localization:()
Synonyms:aotP
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(27) Transport of small molecules
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG4598,COG1126,COG4161
Secondary Functional Category(ies):amino acid biosynthesis and metabolims
EC Number:
Status:ACTIVE
Pathway:






 
Homology:
>gb|AAN70058.1|AE016645_4 (AE016790) basic amino acid ABC transporter, ATP-binding protein
           [Pseudomonas putida KT2440]
          Length = 254

 Score =  362 bits (930), Expect = e-100
 Identities = 177/255 (69%), Positives = 221/255 (86%), Gaps = 1/255 (0%)

>gb|AAL21252.1| (AE008805) histidine and lysine/arginine/ornithine transport
           protein [Salmonella typhimurium LT2]
          Length = 258

 Score =  350 bits (897), Expect = 6e-96
 Identities = 175/252 (69%), Positives = 207/252 (82%)

>gb|AAP17713.1| (AE016986) ATP-binding component of histidine transport [Shigella
           flexneri 2a str. 2457T]
          Length = 257

 Score =  347 bits (891), Expect = 3e-95
 Identities = 172/252 (68%), Positives = 208/252 (82%)






 
Structural Features:
COG4598, HisP, ABC-type histidine transport system, ATPase component 
[Amino acid transport and metabolism]
CD-Length = 256 residues,  97.7% aligned
Score =  435 bits (1119), Expect = 3e-123
Identities = 187/251 (74%), Positives = 216/251 (86%), Gaps = 1/251 (0%)

COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component 
[Amino acid transport and metabolism]
CD-Length = 240 residues,  97.9% aligned
Score =  349 bits (896), Expect = 3e-97
Identities = 137/248 (55%), Positives = 182/248 (73%), Gaps = 13/248 (5%)

COG4161, ArtP, ABC-type arginine transport system, ATPase component 
[Amino acid transport and metabolism]
CD-Length = 242 residues,  99.2% aligned
Score =  227 bits (580), Expect = 9e-61
Identities = 104/249 (41%), Positives = 160/249 (64%), Gaps = 9/249 (3%)







   
Genomic Context:






   
Comment:


















    ReferenceID:6363




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:23505




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:36118




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3180_cdd.html


    		




 
URL:

















    ReferenceID:36419




  
Author/Investigator(s):
        Higgins CF, Haag PD, Nikaido K, Ardeshir F, Garcia G, Ames GF.





  
Title:
        Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium.




  
PubMed:
        7050725


MedLine:
        




    
Source:
Nature. 1982 Aug 19;298(5876):723-7.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7050725









           
Homologs By Global Alignment 

           

       



     
Gene ID:3180
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5113
                           PA2926_tr
                           translation of PA2926
                           255
                           99.21
                           99.60
                           0
                           1286.0
     

     
     
143323
                           gb|AAG06314.1|AE004718_11
                           (AE004718) histidine transport protein HisP [Pseudomonas aeruginosa PAO1]
                           255
                           99.21
                           99.60
                           0
                           1286.0
     

     
     
143324
                           gb|AAQ58530.1|
                           (AE016912) ATP-binding component of histidine transport [Chromobacterium violaceum ATCC 12472]
                           255
                           70.58
                           83.52
                           0
                           930.0
     

     
     
143325
                           gb|AAN70058.1|AE016645_4
                           (AE016790) basic amino acid ABC transporter, ATP-binding protein [Pseudomonas putida KT2440]
                           255
                           69.41
                           86.66
                           1
                           932.0
     

     
     
5114
                           PA0892_tr
                           translation of PA0892
                           255
                           68.62
                           85.88
                           1
                           923.0
     

     






      

          
GC ORFID: 46182How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA2926Glimmer Score: 

          
Start: 2665469Stop: 2666236

          
Length: 768


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA2926 translation of PA2926Homolog Bit Score 499.0

          
Other Homologs:  t_PA0892 (ORF: BLASTX 359.0), psyr_15may02_Scaffold5_revised_gene6103 (ORF: BLASTX 337.0), t_PA5152 (ORF: BLASTX 310.0), psyr_15may02_Scaffold6_revised_gene6950 (ORF: BLASTX 305.0), psyr_15may02_Scaffold2_revised_gene3825 (ORF: BLASTX 254.0), psyr_15may02_Scaffold7_revised_gene7435 (ORF: BLASTX 242.0), t_PA1256 (ORF: BLASTX 233.0), psyr_15may02_Scaffold3_revised_gene4390 (ORF: BLASTX 226.0), psyr_15may02_Scaffold2_revised_gene3873 (ORF: BLASTX 219.0), t_PA1339 (ORF: BLASTX 216.0), psyr_15may02_Scaffold5_revised_gene6133 (ORF: BLASTX 215.0), psyr_15may02_Scaffold7_revised_gene7195 (ORF: BLASTX 214.0), t_PA5074 (ORF: BLASTX 213.0), t_PA4192 (ORF: BLASTX 211.0), psyr_15may02_Scaffold7_revised_gene7291 (ORF: BLASTX 201.0), psyr_15may02_Scaffold7_revised_gene7315 (ORF: BLASTX 147.0), t_PA2926 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGTACAGCCTGCAGGTCGAAGACATCCACAAGCGCTACGGCAGCCATGAGGTGCTCAGGGGCGTTTCGCTC 
AGGGCCGGCAAGGGAGACGTGATCAGCATCATCGGCTCCTCCGGCTCGGGCAAGAGCACCTTCCTGCGCTGC 
GTCAACTTCCTGGAAAAGCCCTGTGCCGGGCGCATCCGCGTCGGCGACGAGGAACTGCGCACCCGTCCCGGC 
GCCCTGGGCGAGCTGCGCGCCGCCGATCCCCGGCAGTTGCAGAGGATCCGCAGCCGGCTGGCGATGGTCTTC 
CAGCATTTCAACCTGTGGAGCCACCTGACGGTGCTGGAGAACGTGGTCGAGTGCCCGGTCAACGTCCTGAGA 
ATGAACCGCGACGACGCCGTGGCCCGCGCGCGCCACTACCTGGCCAAGGTCGGCCTGGCGGAGAAGGTCGAA 
CGGCAGTATCCCTGCGAACTCTCCGGCGGCCAGCAACAGCGCGTGGCGATCGCCCGCGCCCTGGCCATGGAG 
CCGCAGGTGATGCTGTTCGACGAACCGACCTCGGCGCTCGATCCGGAACTGGTCGGCGAAGTGCTGAAAGTC 
ATGCAGCAGTTGGCCGAGGAAGGTCGCACCATGGTCCTGGTCACCCACGAGATGGCCTTCGCCCGCCAGGTT 
TCCAGCCATGTGATCTTCCTCCACCAGGGCGTGATCGAAGAGCAAGGGACGCCGGACCAGGTGTTCGGCGCG 
CCGCGCAGCGAGCGCCTGCGCCAGTTCCTCGCCGGCAACCTGAAATGA