ViewGene
Locus Name:
GeneID:
Location:

GeneID:3168
TrivialName: PA14_17110
AnnotatorUID:
Modification Date/Time:2006-04-06 13:01:23
LocusName:PA14_17110
PAO1 Ortholog Locus:PA3652
Sequence Length:756
Protein Length:251
Start: 1466364
Stop: 1467119
Strand: +
Type:
ChromosomeID:2
Status: ACTIVE
Frame Discrepancy: FALSE
Missense Discrepancy:FALSE
Comments:
Homology: gb|AAG07040.1|AE004785_4 (AE004785) undecaprenyl pyrophosphate synthetase [Pseudomonas aeruginosa PAO1]
Identities = 250/251 (99%), Positives = 250/251 (99%)
Sequence:
ATGGAAAAGACCCGGAAGGATGTGTGCGTGCCACGCCACGTGGCCATTATCATGGACGGTAACAATCGCTGG
GCGAAGAAGCGTCTTCTGCCCGGCGTCGCCGGCCACAAGGCCGGTGTCGATGCCGTCAGGGCGGTGATCGAG
GTCTGCGCCGAGGCAGGGGTCGAGGTCCTCACCCTGTTCGCGTTCTCCAGCGAGAACTGGCAGCGTCCGGCG
GACGAAGTCAGCGCGCTGATGGAACTGTTTCTCGTGGCCCTGCGCCGCGAGGTGCGCAAGCTCGACGAGAAC
GGCATCCGCCTGCGCATCATCGGCGATCGCACGCGTTTCCATCCGGAGTTGCAGGCGGCCATGCGCGAAGCG
GAAGCCGCCACTGCCAGCAATACCCGTTTCCTCCTCCAGGTCGCCGCCAACTACGGCGGCCAGTGGGACATC
GTCCAGGCCGCACAGCGCCTGGCGCGCGAGGTCCAGGGCGGGCACCTGGCGGCGGACGATATCTCCGCCGAG
CTGCTCCAGGGTTGCCTGGTGACCGGCGACCAGCCGCTGCCCGACCTGTGCATCCGCACCGGCGGCGAGCAT
CGCATCAGCAATTTCCTTCTCTGGCAGCTGGCCTACGCCGAGCTGTATTTCTCCGACCTGTTCTGGCCCGAC
TTCAAGCACGCGGCGATGCGGGCTGCCCTGGCGGATTTCTCCAAGCGCCAGCGCCGCTTCGGCAAGACCAGC
GAGCAAGTCGAGGCCGAGGCCCGTCCGTCATGCTGA
Translation:
MEKTRKDVCVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAGVEVLTLFAFSSENWQRPA
DEVSALMELFLVALRREVRKLDENGIRLRIIGDRTRFHPELQAAMREAEAATASNTRFLLQVAANYGGQWDI
VQAAQRLAREVQGGHLAADDISAELLQGCLVTGDQPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPD
FKHAAMRAALADFSKRQRRFGKTSEQVEAEARPSC*
AnnotationID:3176GeneID:3168
AnnotatorUID: diggins
Modification Date/Time: 2005-06-19 10:10:58
Gene Name:uppS
Confidence Code:2
GeneProduct:undecaprenyl pyrophosphate synthetase
Cell Localization:()
Synonyms:yaeS
Cell Localization Confidence Code:5
MolecularFunction:
Functional Category:(7) Cell wall / LPS / capsule
Alternate Gene Product Name:
Functional Category Confidence Code:5
COGs:COG0020,cd00475,pfam01255,KOG1602
Secondary Functional Category(ies):fatty acid and phospholipid metabolism
EC Number:2.5.1.31
Status:ACTIVE
Pathway:
Terpenoid biosynthesis
Homology:
>gb|AAN67216.1|AE016348_8 (AE016779) undecaprenyl diphosphate synthase [Pseudomonas putida
           KT2440]
          Length = 251

 Score =  419 bits (1076), Expect = e-116
 Identities = 209/250 (83%), Positives = 222/250 (88%), Gaps = 2/250 (0%)

>gb|AAN78703.1|AE016755_203 (AE016755) Undecaprenyl pyrophosphate synthetase [Escherichia coli
           CFT073]
          Length = 253

 Score =  259 bits (661), Expect = 1e-68
 Identities = 131/228 (57%), Positives = 159/228 (69%)
Structural Features:
COG0020, UppS, Undecaprenyl pyrophosphate synthase [Lipid metabolism]
CD-Length = 245 residues,  94.3% aligned
Score =  320 bits (822), Expect = 2e-88
Identities = 126/231 (54%), Positives = 168/231 (72%)

cd00475, CIS_IPPS, Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS)
CD-Length = 221 residues, 100.0% aligned
Score =  284 bits (729), Expect = 1e-77
Identities = 112/221 (50%), Positives = 151/221 (68%)

pfam01255, UPP_synthetase, Putative undecaprenyl diphosphate synthase. 
CD-Length = 222 residues, 100.0% aligned
Score =  279 bits (714), Expect = 5e-76
Identities = 113/222 (50%), Positives = 146/222 (65%)

KOG1602, Cis-prenyltransferase 
CD-Length = 271 residues,  88.2% aligned
Score =  234 bits (599), Expect = 1e-62
Identities = 99/240 (41%), Positives = 148/240 (61%), Gaps = 4/240 (1%)
Genomic Context:






   
Comment:


















    ReferenceID:6339




  
Author/Investigator(s):
        GenNotator





  
Title:
        




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:BLASTP 







    
Data:


    		




 
URL:

















    ReferenceID:23481




  
Author/Investigator(s):
        GenNotator





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:RPSBLAST 







    
Data:


    		




 
URL:

















    ReferenceID:31891




  
Author/Investigator(s):
        





  
Title:
        CDD Search




  
PubMed:
        


MedLine:
        




    
Source:






    
Reference Type:Misc (text/plain)







    
Data:3168_cdd.html


    		




 
URL:

















    ReferenceID:34219




  
Author/Investigator(s):
        Apfel CM, Takacs B, Fountoulakis M, Stieger M, Keck W.





  
Title:
        Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.




  
PubMed:
        988266


MedLine:
        




    
Source:
J Bacteriol. 1999 Jan;181(2):483-92.






    
Reference Type:Journal 







    
Data:


    		




 
URL:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9882662









           
Homologs By Global Alignment 

           

       



     
Gene ID:3168
           
Identity:

                               
                                   0%
                               
                                   10%
                               
                                   20%
                               
                                   30%
                               
                                   40%
                               
                                   50%
                               
                                   60%
                               
                                   70%
                               
                                   80%
                               
                                   90%
                               
                                   100%
                               
                             

                           

     
HomologID
                           Accession
                           Description
                           Length
                           PctIdentity
                           PctSimilarity
                           Gaps
                           Score
     

     
     
5095
                           PA3652_tr
                           translation of PA3652
                           251
                           99.60
                           99.60
                           0
                           1290.0
     

     
     
142901
                           gb|AAG07040.1|AE004785_4
                           (AE004785) undecaprenyl pyrophosphate synthetase [Pseudomonas aeruginosa PAO1]
                           251
                           99.60
                           99.60
                           0
                           1290.0
     

     
     
142902
                           gb|AAN67216.1|AE016348_8
                           (AE016779) undecaprenyl diphosphate synthase [Pseudomonas putida KT2440]
                           253
                           82.60
                           87.74
                           4
                           1077.0
     

     
     
142903
                           gb|AAO55058.1|
                           (AE016861) undecaprenyl diphosphate synthase [Pseudomonas syringae pv. tomato str. DC3000]
                           253
                           81.81
                           87.74
                           4
                           1067.0
     

     
     
142906
                           gb|AAQ59873.1|
                           (AE016917) undecaprenyl pyrophosphate synthetase [Chromobacterium violaceum ATCC 12472]
                           260
                           53.07
                           65.76
                           18
                           682.0
     

     






      

          
GC ORFID: 46170How Found: BLASTX

          
GC_TrimmedSeqID: 69Blast Result ID

          
Subject Sequence Name: t_PA3652Glimmer Score: 

          
Start: 3487573Stop: 3486818

          
Length: 756


          
Start Codon: ATGTruncated Start:

          
Stop Codon: TGATruncated Stop: 

          
Homolog: t_PA3652 translation of PA3652Homolog Bit Score 501.0

          
Other Homologs:  psyr_15may02_Scaffold3_revised_gene4623 (ORF: BLASTX 417.0), t_PA3652 (ORF: GLIMMER)

          
GC ORF Sequence

           
ATGGAAAAGACCCGGAAGGATGTGTGCGTGCCACGCCACGTGGCCATTATCATGGACGGTAACAATCGCTGG 
GCGAAGAAGCGTCTTCTGCCCGGCGTCGCCGGCCACAAGGCCGGTGTCGATGCCGTCAGGGCGGTGATCGAG 
GTCTGCGCCGAGGCAGGGGTCGAGGTCCTCACCCTGTTCGCGTTCTCCAGCGAGAACTGGCAGCGTCCGGCG 
GACGAAGTCAGCGCGCTGATGGAACTGTTTCTCGTGGCCCTGCGCCGCGAGGTGCGCAAGCTCGACGAGAAC 
GGCATCCGCCTGCGCATCATCGGCGATCGCACGCGTTTCCATCCGGAGTTGCAGGCGGCCATGCGCGAAGCG 
GAAGCCGCCACTGCCAGCAATACCCGTTTCCTCCTCCAGGTCGCCGCCAACTACGGCGGCCAGTGGGACATC 
GTCCAGGCCGCACAGCGCCTGGCGCGCGAGGTCCAGGGCGGGCACCTGGCGGCGGACGATATCTCCGCCGAG 
CTGCTCCAGGGTTGCCTGGTGACCGGCGACCAGCCGCTGCCCGACCTGTGCATCCGCACCGGCGGCGAGCAT 
CGCATCAGCAATTTCCTTCTCTGGCAGCTGGCCTACGCCGAGCTGTATTTCTCCGACCTGTTCTGGCCCGAC 
TTCAAGCACGCGGCGATGCGGGCTGCCCTGGCGGATTTCTCCAAGCGCCAGCGCCGCTTCGGCAAGACCAGC 
GAGCAAGTCGAGGCCGAGGCCCGTCCGTCATGCTGA